| 空肠弯曲菌耐药机制研究进展 |
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| 引用本文： | 海泉,张焕容,杨发龙,岳华.空肠弯曲菌耐药机制研究进展[J].动物医学进展,2009,30(2). |
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| 作者姓名： | 海泉 张焕容 杨发龙 岳华 |
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| 作者单位： | 西南民族大学生命科学与技术学院,四川成都,610041 |
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| 基金项目： | 国家菌种平台资源项目，西南民族大学博士基金 |
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| 摘 要： | 空肠弯曲菌是一种全球关注的人兽共患病病原菌,由于滥用抗生素而造成其耐药性不断增强,成为公共卫生日益关注的问题.各类抗生素作用位点的基因突变是诱发空肠弯曲菌对各类临床常用的抗生素产生耐药的主要原因,同时细菌对药物的外排机制也在其对抗生素耐药过程中发挥了一定的作用.文章对空肠弯曲菌对各类临床常用抗生素的耐药机制做一综述.
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| 关 键 词： | 空肠弯曲菌 耐药机制 基因突变 药物外排 |
Advance in Mechanism of Antibiotic Resistance in Campylobacter jejuni |
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| HAI Quan,ZHANG Huan-rong,YANG Fa-long,YUE Hua.Advance in Mechanism of Antibiotic Resistance in Campylobacter jejuni[J].Progress In Veterinary Medicine,2009,30(2). |
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| Authors: | HAI Quan ZHANG Huan-rong YANG Fa-long YUE Hua |
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| Institution: | College of Life Science and Technology;Southwest University for Nationalities;Chengdu;Sichuan;610041;China |
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| Abstract: | Campylobacter jejuni is a zoonotic pathogen of global concern.Due to the abuse of antibiotics,antibiotic resistance to Campylobacter jejuni is increasing and becoming a serious public health problem.The gene mutation of antibiotic target sites is the major reason of antibiotic resistance in Campylobacter jejuni.Moreover,alternation of drug efflux mechanism plays an important role in formation of antibiotic resistance.This paper reviewed the mechanims of resistance to commonly used antibiotics in Campylobact... |
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| Keywords: | Campylobacter jejuni mechanism of resistance gene mutations drug efflux |
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