| 纳米氧化锌对断奶仔猪生长性能和肠黏膜屏障的影响 |
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| 引用本文： | 胡彩虹,游兆彤,朱康,栾兆双.纳米氧化锌对断奶仔猪生长性能和肠黏膜屏障的影响[J].动物营养学报,2012(2):285-290. |
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| 作者姓名： | 胡彩虹 游兆彤 朱康 栾兆双 |
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| 作者单位： | 浙江大学饲料科学研究所;浙江省农业科学院病毒学与生物技术研究所 |
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| 基金项目： | 国家自然科学基金(31072039);浙江省自然科学基金(Y3100072) |
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| 摘 要： | 本文旨在研究纳米氧化锌对断奶仔猪生长性能和肠黏膜屏障的影响及其机理。选用96头平均体重为(5.7±0.2)kg的21日龄"杜×长×大"断奶仔猪,随机分成3组:1)对照组,饲喂基础饲粮;2)氧化锌组,饲喂在基础饲粮中添加3 000 mg/kg锌(氧化锌)的试验饲粮;3)纳米氧化锌组,饲喂在基础饲粮中添加300 mg/kg锌(纳米氧化锌)的试验饲粮。每组4个重复,每个重复8头仔猪,试验期14 d。结果表明:1)与对照组相比,纳米氧化锌组断奶仔猪平均日增重提高了7.26%(P<0.05),腹泻率降低了70.82%(P<0.05),但与氧化锌组差异不显著(P>0.05)。2)与对照组相比,纳米氧化锌组仔猪28和35日龄绒毛高度分别提高了12.64%和10.80%(P<0.05);28日龄隐窝深度降低了15.42%(P<0.05);28和35日龄绒毛高度/隐窝深度分别提高了33.61%和17.11%(P<0.05);28和35日龄血浆D-乳酸含量分别降低了28.97%和20.23%(P<0.05),二胺氧化酶活性分别降低了28.61%和24.92%(P<0.05)。氧化锌组和纳米氧化锌组之间各指标差异不显著(P>0.05)。结果提示,断奶仔猪饲粮中添加300 mg/kg锌(纳米氧化锌)可提高平均日增重,降低腹泻率,改善肠黏膜形态,降低肠黏膜通透性,其效果与添加3 000 mg/kg锌(氧化锌)相当。
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| 关 键 词： | 纳米氧化锌 断奶仔猪 腹泻率 肠黏膜屏障 |
Effects of Nano Zinc Oxide on Growth Performance and Intestinal Mucosal Barrier in Weaner Piglets |
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| HU Caihong,YOU Zhaotong,ZHU Kang,LUAN Zhaoshuang.Effects of Nano Zinc Oxide on Growth Performance and Intestinal Mucosal Barrier in Weaner Piglets[J].Acta Zoonutrimenta Sinica,2012(2):285-290. |
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| Authors: | HU Caihong YOU Zhaotong ZHU Kang LUAN Zhaoshuang |
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| Institution: | 1(1.Institute of Feed Science,Zhejiang University,Hangzhou 310058,China;2.Institute of Virology and Biotechnology Research,Zhejiang Academy of Agricultural Sciences,Hangzhou 310021,China) |
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| Abstract: | This experiment was conducted to study the effects of nano zinc oxide on growth performance and intestinal mucosal barrier in weaner piglets.Ninety-six ’Duroc × Landrace × Yorkshire’ crossbred piglets with an average body weight of(5.7±0.2) kg were weaned at 21 days of age and randomly allocated into control group,zinc oxide group and nano zinc oxide group(4 replicates in each group and 8 piglets per replicate).A basal diet was the diet of control group,a basal diet supplemented with 3 000 mg/kg zinc as zinc oxide was the diet of zinc oxide group,and a basal diet supplemented with 300 mg/kg zinc as nano zinc oxide was the diet of nano zinc oxide group,respectively.Feeding trial lasted for 14 days.The results showed that the diet of nano zinc oxide group improved average daily gain(P<0.05) and decreased diarrhea rate of piglets(P<0.05) compared with the diet of control group.There was no significant difference in growth performance and diarrhea rate between the piglets of nano zinc oxide group and the piglets of zinc oxide group(P>0.05).The piglets of nano zinc oxide group had higher villus height and villus height/crypt depth(P<0.05),lower plasma D-lactate content and diamine oxidase activity(P<0.05) compared with the piglets of control group.No significant difference in intestinal mucosal barrier was found between the piglets of nano zinc oxide group and the piglets of zinc oxide group(P>0.05).The results indicate that the diet supplemented with 300 mg/kg zinc as nano zinc oxide can protect intestinal mucosal barrier,decrease diarrhea rate and improve growth performance,which is comparable to the effect of the diet supplemented with 3 000 mg/kg zinc as zinc oxide. |
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| Keywords: | nano zinc oxide weaner piglets diarrhea rate intestinal mucosal barrier |
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