| DNA甲基化对早期胚胎发育的影响 |
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| 引用本文： | 申艳丽,张华林,陈世林,吴琰,杨利国.DNA甲基化对早期胚胎发育的影响[J].畜牧与饲料科学,2011(11):40-42. |
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| 作者姓名： | 申艳丽 张华林 陈世林 吴琰 杨利国 |
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| 作者单位： | 农业动物遗传育种与繁殖教育部重点实验室华中农业大学动物科技学院,湖北武汉,430070 |
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| 摘 要： | 综合分析了DNA甲基化的表观遗传特征,结合DNA甲基化在不同物种、不同发育阶段胚胎中的调控模式,以期从早期胚胎死亡角度揭示DNA甲基化作用对胚胎早期发育基因的表达调控作用,进而阐明胚胎发育过程中的表观遗传调控机制。
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| 关 键 词： | DNA甲基化 表观遗传 早期胚胎死亡 胚胎发育 |
Effect of DNA Methylation on Early Embryonic Development |
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| SHEN Yan-li,ZHANG Hua-lin,CHEN Shi-lin,WU Yan,YANG Li-guo.Effect of DNA Methylation on Early Embryonic Development[J].Animal Husbandry and Feed Science,2011(11):40-42. |
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| Authors: | SHEN Yan-li ZHANG Hua-lin CHEN Shi-lin WU Yan YANG Li-guo |
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| Institution: | (Ministry of Education Key Laboratory for Agriculture Animal Heredity and Breeding,College of Animal Science and Technology,Huazhong Agricultural University,Wuhan 430070,China) |
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| Abstract: | This paper analyzes the epigenetie inheritance characteristics of DNA methylation, and combined with the regulation pattern of DNA methylation in different species and different developmental stages of embryos, the role of DNA methylation in early development of embryos regulation of gene expression is reviewed from the perspective of early embryonic death, and thus to clarify the mechanism of epigenetic regulation during embryonic development. |
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| Keywords: | DNA methylation epigenetic inheritance early embryonic death embryonic development |
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