Expression of the bovine leukemia virus transactivator protein p34 by a recombinant vaccinia virus |
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| Authors: | L Willems C Letellier M Gonze R Martin R Kettmann A Burny G Meulemans |
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| Institution: | Faculty of Agronomy, Gembloux, Belgium. |
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| Abstract: | In order to characterize the bovine leukemia virus transactivator protein, a recombinant vaccinia virus (v-LOR) containing the BLV post-envelope long open reading frame was constructed. v-LOR was shown to encode a functional protein able to transactivate the BLV long terminal repeat-directed gene expression in the infected cells. The encountered level of transactivation was about one third of that measured in BLV-infected fetal lamb kidney cell lysates. |
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