Effect of the route of administration on the mucosal and systemic immune responses to Lawsonia intracellularis vaccine in pigs |
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| Authors: | MG Nogueira AM Collins RH Dunlop D Emery |
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| Institution: | 1. Farm Animal and Veterinary Public Health, University of Sydney, Camden, New South Wales, Australia;2. NSW Department of Primary Industries, Elizabeth Macarthur Agricultural Institute, Narellan, New South Wales, Australia;3. Chris Richards and Associates Pty Ltd, East Bendigo, Victoria, Australia |
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| Abstract: | In an on‐farm study, 40 weaned piglets aged 3 weeks were vaccinated with Lawsonia intracellularis vaccine orally, IM or IP while a fourth group remained unvaccinated. All vaccinated animals showed increased serum levels of L. intracellularis‐specific IgG antibodies, but significantly elevated concentrations of specific IgG, IgA and cytokines were generated in ileal mucosal secretions from the orally and IP vaccinated pigs when examined at 17 days after vaccination. |
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| Keywords: | immunity Lawsonia intracellularis pigs vaccination |
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