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Mixed infections of rotaviruses and Campylobacter jejuni in Caco-2 cells
Authors:Hänel I  Elschner M  Berndt A  Otto P
Institution:Bundesinstitut für gesundheitlichen Verbraucherschutz und Veterin?rmedizin, Fachbereich 4 Bakterielle Tierseuchen und Bek?mpfung von Zoonosen, Jena. i.haenel@bgvv.de
Abstract:A mixed infection with rotavirus and 3 different Campylobacter jejuni strains was analysed in Caco-2 cells, a cell line highly susceptible to these pathogens. The results obtained showed no influence of the virus preinfection on the Campylobacter jejuni adhesion or internalisation in Caco-2 cells. Confocal laser scanning microscopy of mixed infected cells confirmed these results. The data from the present study indicate that specific rather than nonspecific mechanisms are involved in the interaction between rotavirus, campylobacter and host cells.
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