| Ghrelin生物学功能的研究进展 |
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| 引用本文： | 陈斌,吴天星.Ghrelin生物学功能的研究进展[J].中国畜牧杂志,2005,41(10):64-66. |
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| 作者姓名： | 陈斌 吴天星 |
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| 作者单位： | 1. 浙江大学动物科学学院,浙江,杭州,310029
2. 浙江大学理学院,浙江,杭州,310027 |
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| 摘 要： | Ghrelin是一种在大鼠和人胃内新发现的生长激素促分泌素受体(GHS-R)的内源性配基,有28个氨基酸,起促生长激素释放作用。当Ghrelin与位于垂体和下丘脑的GHS-R结合后,产生一系列生物学效应。本文从生长激素释放、机体生长发育、食欲和采食量、能量代谢、胃酸分泌等方面综述了Ghrelin的生物学功能,并初步探讨其在畜牧业上的应用前景。
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| 关 键 词： | 畜牧、兽医科学基础学科 Ghrelin 综述 生长激素 能量代谢 |
| 文章编号： | 0258-7033（2005）10-0064-03 |
| 收稿时间： | 2004-01-28 |
| 修稿时间： | 2004-05-17 |
Recent Advances in the Biological Function of Ghrelin |
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| CHEN Bin,WU Tian-xing.Recent Advances in the Biological Function of Ghrelin[J].Chinese Journal of Animal Science,2005,41(10):64-66. |
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| Authors: | CHEN Bin WU Tian-xing |
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| Abstract: | Ghrelin,a novel 28-amino-acid peptide purified from rat and human stomachs,is the endogenous ligand for the growth hormone secretagogue receptor(GHS-R) and has strong growth hormone-releasing activity.Ghrelin displays the physiological effects through the binding with GHS-R in the hypothalamus and pituitary.Functionally,ghrelin not only increases the GH release,but also is related to body growth,appetite,food intake,energy metabolism,and gastric acid secretion.This review summarized recent developments on structure,distribution,biological functions of ghrelin as well as its potential application in animal husbandry. |
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| Keywords: | basal disciplines of animal and veterinary science Ghrelin a review growth hormone energy metabolism |
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