| 河南省部分地区猪源大肠杆菌耐药基因floR、CTX-M、mcr-1的分子流行病学调查 |
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| 引用本文： | 赵公锦,彭丽,方忠意,吴宁鹏,李金磊,李孟,吴志明.河南省部分地区猪源大肠杆菌耐药基因floR、CTX-M、mcr-1的分子流行病学调查[J].中国兽药杂志,2020,54(11):1-7. |
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| 作者姓名： | 赵公锦 彭丽 方忠意 吴宁鹏 李金磊 李孟 吴志明 |
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| 作者单位： | 河南农业大学,,,,,,河南省兽药饲料监察所 |
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| 摘 要： | 为掌握河南省猪源大肠杆菌耐药基因floR、CTX-M、mcr-1的分布和流行情况，对2013-2018年从河南省内分离的856株大肠杆菌进行floR、CTX-M、mcr-1等三种耐药基因筛查检测，调查其分布特征，并对猪源大肠杆菌耐药基因在郑州、开封、焦作、许昌四个地区的分布和流行趋势进行了分析研究。结果显示，2013-2018年floR基因的检出率一直保持在较高水平，CTX-M基因的检出率持续增长，mcr-1基因的检出率在2014年达到最高，之后逐年下降，直到2018年未检出，并且不同地区耐药基因的流行趋势有一定差异。
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| 关 键 词： | 猪源大肠杆菌 耐药基因 分子流行病学 |
| 收稿时间： | 2020/5/11 0:00:00 |
| 修稿时间： | 2020/11/2 0:00:00 |
Molecular epidemiological investigation of swine-resistant E.coli resistance genes floR, CTX-M, and mcr-1 in parts of Henan Province |
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| Institution: | Henan Agricultural University,,,,,, |
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| Abstract: | To grasp the distribution and prevalence of floR, CTX-M, mcr-1 of pig-derived E. coli resistance genes in Henan Province, 856 strains of E. coli isolated from Henan Province from 2013 to 2018 were screened and tested for three drug resistance genes including floR, CTX-M and mcr-1, and their distribution characteristics were investigated. The distribution and epidemic trends of pig-derived E. coli resistance genes in Zhengzhou, Kaifeng, Jiaozuo, and Xuchang were analyzed and studied. The results showed that the detection rate of the floR gene had been maintained at a relatively high level from 2013 to 2018. The detection rate of the CTX-M gene had continued to increase. The detection rate of the mcr-1 gene reached its highest level in 2014 and then declined year by year, not detected until 2018. And there was a certain difference in the prevalence of drug resistance genes in different regions. |
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