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豆状囊尾蚴是豆状带绦虫的中绦期幼虫,主要感染家兔等兔形目动物.豆状囊尾蚴病是家兔寄生虫病中较普遍和较严重的一种,由于无明显的临床症状,未能引起养殖户的足够重视,因而临床用药不规范,治疗效果欠佳,严重影响了中国养兔业的发展.因此,作者综述了兔豆状囊尾蚴病的病原形态、分子生物学、流行病学、致病性、诊断与免疫预防等方面的研究进展,为兔豆状囊尾蚴病的防控及相关研究提供参考. 相似文献
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《畜牧兽医学报》2019,(11)
旨在鉴别无钩豆状囊尾蚴与有钩豆状囊尾蚴的区别。用扫描电镜对自然感染的豆状囊尾蚴头节进行超微结构观察,对其18S DNA进行PCR扩增和序列分析,并与其他动物的囊尾蚴作了进化树比较。结果显示:超微结构观察无钩和有钩豆状囊尾蚴的主要区别位于顶突,而吸盘和原始体节的结构是相同的。从囊泡中取出的豆状囊尾蚴多处于相对静止状态。无钩豆状囊尾蚴的顶突如同数层圆饼叠放在一起,表面比较平坦,中央有一个较大的结节,结节的直径约为20μm,周边有数层齿轮状花纹,形成重合式齿轮状构造。有钩豆状囊尾蚴顶突的前端比较钝,通过皮肌柱与形似鸡爪样的小钩相连。小钩表面光滑,富有光泽,具有坚硬的外观,长120～150μm。通过用18S-P1和18S-P2引物对无钩和有钩豆状囊尾蚴的目的基因、感受态细胞的培养液和菌体质粒的PCR检测,均获得相同的目的基因条带。测序结果表明18S-P1引物扩增的无钩豆状囊尾蚴与有钩豆状囊尾蚴750 bp序列的差别比18S-P2引物扩增的666 bp序列的区别明显。与其他动物囊尾蚴相关序列的进化比较显示,无钩豆状囊尾蚴与牛囊尾蚴有亲缘性,而有钩豆状囊尾蚴则与猪囊尾蚴有亲缘关系。总之,无钩和有钩豆状囊尾蚴虽然同属豆状囊尾蚴,但无钩豆状囊尾蚴是一种新发现的豆状囊尾蚴。 相似文献
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为分析不同驱虫药对感染豆状囊尾蚴肌肉营养成分含量的影响,本试验采用3种抗蠕虫药（甲苯咪唑、吡喹酮、丙硫苯咪唑）对人工感染豆状囊尾蚴家兔进行驱虫试验,并对感染豆状囊尾蚴后和驱虫后家兔肌肉营养成分（水分、灰分、脂肪和蛋白质）含量变化进行分析。结果表明,3种抗蠕虫药对家兔感染豆状囊尾蚴均有不同程度的驱虫效果,家兔肌肉营养成分含量有不同程度的升高。其中,甲苯咪唑和丙硫苯咪唑对家兔肌肉中的水分、脂肪和蛋白质含量影响较大,吡喹酮驱虫后家兔肌肉中灰分含量增加较明显。 相似文献
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本研究旨在观察豆状囊尾蚴在不同状态下的超微结构。从肉联厂屠宰检验采取豆状囊尾蚴,直接剪破囊泡从中取出豆状囊尾蚴;或用含10%胆汁生理盐水培养囊尾蚴,待其从囊泡中翻出后,用扫描电镜观察和记录。位于囊泡内的头节,从其顶端观察,顶突呈伞状,皮肌柱连接小钩覆盖于头节的前端。从侧面观察,一排有鹿角样的小钩附着于顶突。4个吸盘呈洞穴状位于顶突之后分布在头节的四周。原始颈节较宽,体节较细,表面均有许多皱褶。培养后的豆状囊尾蚴可明显区分为头节、颈节、体节和囊泡区,顶突上的皮肌柱收缩,鹿角样的小钩向周围伸展,吸盘也发生环形和纵形收缩,颈节的环状收缩和体节的纵行收缩均明显可辨。豆状囊尾蚴处于不同状态时,其超微结构明显不同。 相似文献
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Cody V Shen H Shlyankevich M Tigelaar RE Brandsma JL Hanlon DJ 《Veterinary immunology and immunopathology》2005,103(3-4):163-172
The in vitro generation of dendritic cells (DCs) from either blood or bone marrow has been accomplished for humans and a number of other species. This ability has facilitated the opportunity to test the efficacy of DC vaccines in various tumor models. The cottontail rabbit papillomavirus (CRPV) model is the most clinically relevant animal model for human papillomavirus (HPV)-associated carcinogenesis. The CRPV model has been used to test various preventative and therapeutic vaccination strategies, and the availability of rabbit DCs would further expand its utility. However, to date, rabbit DCs have not been phenotypically and/or functionally characterized. Here we show that DCs can be generated in vitro from rabbit bone marrow mononuclear cells (BMMCs) cultured in the presence of the human cytokines GM-CSF and IL-4 and matured with lipopolysaccharide (LPS). These cells show upregulation of MHC class II and CD86, as well as downregulation of CD14, do not have non-specific esterase activity, are able to perform receptor-mediated endocytosis, and are potent stimulators of allogeneic T cell proliferation in mixed lymphocyte reactions. The ability to generate rabbit DCs makes it possible to test the efficacy of DC vaccination in the prevention and treatment of CRPV-induced lesions, which may provide useful preclinical data regarding the use of DC vaccines for HPV-associated lesions, including cervical cancer. 相似文献
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Extensive mineralization of the aorta, brachiocephalic trunk, and the left subclavian, both iliac, common carotid, and renal arteries were found at necropsy in a 3-year-old French Lop rabbit. The rabbit had been examined previously for seizures, at which time abdominal radiography revealed calcification of the abdominal aorta and external iliac arteries. Treatment was not initiated, and the rabbit died 4 months later of bacterial pneumonia. The rabbit also had hypercalcemia. In contrast to many species, the blood calcium concentrations of rabbits reflect dietary intake. 相似文献
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Myxoma virus (MV) is a poxvirus that evolved in Sylvilagus lagomorphs, and is the causative agent of myxomatosis in European rabbits (Oryctolagus cuniculus). This virus is not a natural pathogen of O. cuniculus, yet is able to subvert the host rabbit immune system defenses and cause a highly lethal systemic infection. The interaction of MV proteins and the rabbit immune system has been an ideal model to help elucidate host/poxvirus interactions, and has led to a greater understanding of how other poxvirus pathogens are able to cause disease in their respective hosts. This review will examine how MV causes myxomatosis, by examining a selection of the identified immunomodulatory proteins that this virus expresses to subvert the immune and inflammatory pathways of infected rabbit hosts. 相似文献
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Development of the New Zealand White Rabbit Eye: I. Pre‐ and Postnatal Development of Eye Tunics 
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下载免费PDF全文 The New Zealand white (NZW) rabbit has been and is right now regularly utilized in ophthalmic surgery evaluation. Inside NZW rabbit eye, the visibility of ocular structures throughout surgical procedure is fantastic. Younger rabbits are used in different ages for the evaluation of ophthalmic surgery. Complete studies of ocular development in the NZW rabbits have not been reported previously. The aim of the present investigation was to describe the major landmarks and the time course of the pre‐ and post‐natal development of the complete eye tunics of the NZW rabbit to give a superb model as well as a fruitful area for further ophthalmological investigations. Serial histological sections of NZW rabbit prenatal (E13–E28) and post‐natal (P1–P14) stages were examined, respectively. The eye of the NZW rabbit developed in a similar manner to that of the human and domestic animals eyes; the principal differences were at the time of occurrence of certain developmental events, absence of pigmentation which represent an exploited benefit for ophthalmic surgery, remarkable Bowman's membrane at E25, poor developed ciliary stroma and juvenile retinal layer until P9. In human, the basic morphogenetic processes of the development of eye tunics are completed towards the end of the first half of gestation period. However, the latter represents the beginning stage of the development of eye tunics in the rabbit. Thus, allowing various extensive ophthalmic researches to be performed. 相似文献
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JL FRATER 《Australian veterinary journal》2001,79(9):608-611
Chronic hypervitaminosis A can occur in many species after excessive dietary intake of Vitamin A (retinol). The most common presentation of chronic hypervitaminosis A is a polyarthropathy with hyperostosis and ankylosis of various joints. This case report describes a probable case of naturally occurring hypervitaminosis A-induced polyarthropathy in a rabbit after chronic ingestion of a diet made up almost exclusively of carrots. Carrots do not contain retinol, but are rich in provitamin A (or beta-carotene). Rabbits are unique in that they can convert 100% of dietary beta-carotene into retinol. A syndrome of naturally occurring hypervitaminosis A-induced polyarthropathy has not been described in a rabbit before. 相似文献
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通过对目前省内家兔免疫程序的调查，结果表明：大多数地区只用了兔瘟巴魏三联苗或兔瘟－巴氏杆菌病二联疫苗免疫，免疫程序不够合理。对其存在的问题，笔者作出了原因分析，并根据兔病流行的特点，提供了家兔的基础免疫程序，同时对免疫失败的原因也进行了分析总结。 相似文献
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This investigation addresses the possibility of providing mouse embryos or other foreign objects with a protective mucin coat by transferring them into the oviduct of a life rabbit doe. Mouse embryos at the 8 or 16-cell stage, rabbit oocytes and latex spheres resembling mouse embryos in size were transferred to the ligated oviducts of ovulation-induced rabbit does. The does were killed 24 h later to have their oviducts flushed. A large proportion of the latex spheres (89%) and of the ovulated oocytes of the recipient does (92%) was recovered. The recovery rates for transferred rabbit oocytes, either intact or with the zona pellucida removed, were 61% and 51%, respectively, whereas that for mouse embryos was extremely poor (20%). Rabbit oocytes with or without zona were enveloped in a thick mucin coat regardless whether they had been transferred or ovulated by the recipients. The same applied to empty rabbit zonae. Mouse embryos and latex spheres were also covered by a mucin coat, but it was four times thinner. While residing in the rabbit oviduct, the mouse embryos continued developing to a stage comparable to what would have been expected in situ . During the subsequent in vitro culture, mouse embryos continued developing to the expanded blastocyst stage. They did, yet, not hatch from the zona. It may be concluded that particles of various origins, when placed into the oviduct of ovulated rabbit does, will be provided with a mucin covering which is, however, considerably thinner than that surrounding oocytes or zonae pellucidae originating from rabbits. 相似文献
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兔胚胎体外培养液研究进展 总被引：3，自引：0，他引：3
兔胚胎体外培养研究受到广泛重视。传统的兔胚胎体外培养方法主要采用基础培养液 ,添加各种成分 ,如血清、生长因子、酶及其他营养成分促进胚胎发育。近年来 ,国内外学者对氨基酸、牛磺酸和亚牛磺酸等能源物质 ,胰岛素及胰岛素样因子 1、碱性成纤维细胞生长因子、血小板活化因子、血小板衍生生长因子和白血病抑制因子等多种生长因子 ,以及抗氧化剂如EDTA、过氧化氢酶、牛磺酸和超氧化物歧化酶等物质促进兔早期胚胎发育的作用进行了研究。此外 ,采用联合培养体系及体细胞条件培养液 ,模拟体内生长环境 ,来提供兔胚胎发育所需的物质条件也正成为研究热点 相似文献