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羔羊腹泻是一种复杂的多因素综合征,细菌和病毒感染是致羔羊发生腹泻的2种常见因素。常见的致腹泻细菌病原包括大肠杆菌、沙门氏菌和产气荚膜梭菌,病毒病原包括轮状病毒、牛病毒性腹泻病毒、腺病毒、星状病毒等。该文对致羔羊腹泻的主要细菌和病毒病原进行综述,旨在为羔羊腹泻疾病的防控和治疗提供参考。 相似文献
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引起腹泻的病原非常复杂,对羔羊会造成很大危害,疾病的流行没有明显的季节性和规律性,一直被相关学者、畜牧兽医工作人员以及饲养户所重视。1病因分析多种原因都会造成羔羊腹泻,除了感染致病细菌和病毒引起发病以外,传染性疾病和营养不佳,以及环境的温度和突然改变饲草饲料等,都会导致羔羊腹泻。7日龄以内羔羊特别容易感染腹泻,2~3日龄的羔羊多发,临床中表现为腹泻、下痢为主要特征,每年产羔季节会出现羔羊死亡的情况,必然会给 相似文献
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羔羊腹泻已成为羔羊疾病中引起死亡的一个重要因素,由病毒、细菌、寄生虫等病原加上不科学的饲养管理、小气候环境及应激等因素引起羔羊腹泻。本文总结了羔羊腹泻的发生原因,并提出了做好驱虫、消毒、免疫注射,预防用药,饲喂优质牧草或青贮饲草、科学配比,提高羊群自身免疫力和抗病能力等措施。 相似文献
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腹泻是羔羊的常见疾病,一年四季均可发生,本病是引起羊羔生长发育不良和死亡的主要疾病之一。引起羔羊腹泻的原因较多,微生物感染,营养不良,外界环境温度突变以及饲草饲料的变化等均可引起羔羊腹泻。笔者通过对羊场600余只羔羊培育过程的观察研究,总结出如下综合性防治措施。1羔羊腹泻的发病原因(1)病原微生物引起的原发或继发性腹泻。病原微 相似文献
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羔羊腹泻是新生羊羔所发生的一种急性腹泻,是由于肠道内细菌、病毒等病原微生物或者营养、环境性因素致使新生羔羊免疫力下降,导致羔羊发病率高,死亡率可达20%~30%,该病为养羊业造成巨大的经济损失。 相似文献
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羔羊病原性腹泻是一种肠道功能受损、排便异常且具有传染性的疾病，临床表现主要为腹泻和机体中毒等症状，不仅会对羔羊的正常生长发育造成影响，严重者还会导致死亡。目前，最好的防治方法是在生产前后对生产环境及羔羊机体的预防保护，同时选用合适的药物进行治疗，降低羔羊病原性腹泻的发病率，对促进羔羊养殖业的发展具有深远意义。本文就羔羊腹泻发病的病原性因素进行了全面的分析，并提出综合防治措施，供从业人员参考。 相似文献
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TUO Xin LIU Yong-ming HUANG Mei-zhou CUI Dong-an WANG Hui WANG Sheng-yi QI Zhi-ming 《中国畜牧兽医》2016,43(3):831-836
The etiology of lamb diarrhea disease is complex,however,bacterial and viral infection are the most critical factors and cause most serious harm.In order to explore the main pathogens of lambdiarrhea,many scholars and experts have undertaken extensive research on different aspects of viral and bacterial etiology of lamb diarrhea with various methods.Recently,the research about the etiology concentrates on the main code genes and functional proteins in the progress of pathogen invading host and molecular epidemiology.This paper reviewed the recent and main pathogens of lamb diarrhea caused by bacteria and viruses from the molecular level,and proposed some ideas about the development of etiology of lamb diarrhea in the future. 相似文献
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Denno DM Klein EJ Young VB Fox JG Wang D Tarr PI 《Animal health research reviews / Conference of Research Workers in Animal Diseases》2007,8(1):69-80
Gastrointestinal illnesses are common afflictions. However, knowledge of their etiology is often lacking. Moreover, most cases of infections with reportable enteric pathogens (Campylobacter jejuni, Escherichia coli O157:H7, Salmonella, Shigella, Yersinia, Cryptosporidia and Giardia) have sporadic modes of acquisition, yet control measures are often biased towards mitigation of risks discerned by outbreak analysis. To determine the etiology of unexplained diarrhea it is important to study populations that can be matched to appropriate controls and to couple thorough classic microbiologic evaluation on receipt of specimens with archiving and outgrowth capabilities. Research evaluations should address the potential roles of a broad panel of candidate bacterial pathogens including diarrheagenic E. coli, Listeria monocytogenes, Helicobacters and jejuni Campylobacters, and also apply novel massively parallel sequencing and nucleic acid detection technologies that allow the detection of viral pathogens. To fill voids in our knowledge regarding sources of known enteric pathogens it will be critical to extend case-control studies to assess risk factors and exposures to patients with non-epidemic illnesses and to appropriate controls. By filling these gaps in our knowledge it should be possible to formulate rational prevention mechanisms for human gastrointestinal illnesses. 相似文献
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牛病毒性腹泻病毒（bovine viral diarrhea virus,BVDV）是导致牛腹泻的重要致病病毒之一,BVDV感染不仅能造成严重的临床症状,且可导致患畜的免疫力降低从而感染其他病原,致使患病动物的发病率和死亡率大大增加,给养牛业造成重大的损失。随着近年来分子生物学相关理论及技术不断发展,对于BVDV的研究逐渐深入,人们对该病毒的分子生物学方面有了一些新的了解,作者主要从BVDV的病毒粒子结构组成及功能、国内外的流行情况和BVDV基因的遗传与变异情况3个方面阐述近几年BVDV的分子生物学研究进展。 相似文献
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Bovine viral diarrhea virus (BVDV) is one of the most important pathogenic viruses which mainly causes bovine viral diarrhea disease (BVD). BVDV can not only cause serious clinical symptoms, but also lead to decrease of immunity of livestock and infect other pathogens, resulting in significant increase of morbidity and mortality of sick animals, and causes significant losses to the cattle industry. With the development of molecular biology theory and technology in recent years, the research on BVDV has been deepening, and some new understandings have been made to the molecular biology of the virus. In this paper, the progress of molecular biology of BVDV in recent years is described from three aspects of the composition and function of virus, the epidemic situation of BVDV gene and the genetic and mutation of BVDV gene. 相似文献
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牛病毒性腹泻病毒侵染细胞机制的研究进展 总被引：2，自引：0，他引：2
牛病毒性腹泻病毒(BVDV)是反刍动物和猪体内广泛存在的危害动物健康的重要病原体.BVDV感染牛后主要引起牛的持续性感染、免疫耐受、免疫抑制、繁殖障碍及急慢性黏膜病等临床症状,给养牛业造成重大的损失.其致病机理非常复杂,给该病的治疗和根除带来极大的困难.随着分子病毒学研究的发展以及对猪瘟病毒和黄病毒科其他成员的研究,人们在BVDV分子水平和细胞水平的研究方面也取得了一些进展.就此,作者从BVDV入侵细胞、在细胞内的复制以及与宿主蛋白分子相互作用等方面进行综述,有助于阐明BVDV致病和在体内持续存活的机制,为该病的防治和疫苗研发提供新的思路和对策. 相似文献
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羔羊痢疾是一种细菌性肠道疾病,此类疾病主要由大肠杆菌、魏氏梭菌、沙门氏菌、肠球菌引起。病菌通过口咽道进入动物体内,并随着粪便排泄出来,造成肠道炎症和病原体的大量排放,同时也会导致严重的腹泻和消化道不适。随着羊养殖规模的增加和养殖密度的增加,羔羊痢疾的发生频率逐渐上升,对其生命和健康造成严重损害,必须引起高度重视。 相似文献
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Jianwen Chen Kaiyuan Pan Zhen Chen Yunsheng Li Biao Ding Chunyang Han Zubing Cao Wenbin Bao Yunhai Zhang 《Animal Science Journal》2019,90(3):366-371
Porcine viral diarrhea is an acute and highly contagious enteric disease in pigs which causes huge economic losses in pig industry worldwide. Transmissible gastroenteritis virus (TGEV) is main pathogens responsible for piglets viral diarrhea. Knockout the host cellular surface receptor for TGEV may be an effective way to accelerate the breeding of resistant pigs. In this study, we applied site‐specific editing pAPN which is effective in swine testis (ST) cells. Site‐specific editing of pAPN reduced TGEV proliferation in ST cells by 96%–99% at different time periods post‐infection. Next, the site‐specific editing of pAPN porcine fetal fibroblasts were produced, and then the cell colonies were used as donor cells to generate the site‐specific editing of pAPN pigs. Our research findings will not only offer a more thorough understanding of the pathogenesis of piglet diarrhea and lay the foundation for breeding TGEV‐resistant piglets, but also understanding the molecular mechanisms involved in coronaviral infections. 相似文献
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