共查询到19条相似文献，搜索用时 265 毫秒
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应用害获灭注射剂按0.2 mg/kg体重剂量皮下注射,对黄牛自然感染的牛痒螨进行驱杀效果观察,并设空白对照组.结果显示,对初期感染牛痒螨的病牛,一次用药可杀灭大部分虫体;对于病期较长,严重感染牛痒螨的病牛间隔7 d～10 d进行第2次用药,其驱除率可达100%. 相似文献
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应用害获灭注射剂按0.2 mg/kg体重剂量皮下注射给药,对自然感染痒螨的病羊进行治疗效果观察,并设空白对照组.结果表明,对感染绵羊痒螨的病羊进行2次用药治疗,即第1次用药后间隔10 d进行第2次用药,可完全杀灭绵羊痒螨,治愈率达100%,对未感染羊进行预防注射,可阻止痒螨的传播. 相似文献
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应用伊维菌素片剂,对自然感染绵羊痒螨的29只病羊进行治疗效果试验,并设阳性对照组.结果:伊维菌素治疗组绵羊在用药后48～72 h,瘙痒症状明显减轻,用药后21d检查,未查到活的痒螨.试验表明,伊维菌素0.2mg/ks体重剂量对初期感染绵羊痒螨的病样一次给药即可治愈;对严重感染者间隔7～10d再次给药具有良好的杀螨效果. 相似文献
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张履忠 《青海畜牧兽医杂志》2013,43(3)
应用伊维菌素注射剂,对自然感染牛痒蜻的29头黄牛进行治疗效果试验,并设阳性对照组.结果:伊维菌素治疗组黄牛在用药后72～96h,瘙痒症状明显减轻,用药后21d检查,未查到活的牛痒螨.试验表明,伊维菌素0.2mg/kg体重剂量对初期感染牛痒螨的病牛一次给药即可治愈;对严重感染者间隔10d再次给药具有良好的杀螨效果. 相似文献
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为了研究阿维菌素长效注射液(油悬剂)对绵羊痒螨疗效,将60只自然感染痒螨绵羊随机分为3组,每组20只。第1组每千克体重颈部皮下注射1 mg的阿维菌素油悬剂,第2组注射0.2 mg的阿维菌素普通注射液,第3组为不给药对照组。在给药后第7、14、21、28、35、42、49、56、63、70天对所有绵羊进行螨虫检查和计数,每天观察病变。结果表明:给自然感染痒螨的绵羊皮下注射1 mg/kg的阿维菌素长效注射液(油悬剂)可在给药后7 d内将痒螨完全杀灭,在给药后63 d内防止绵羊被痒螨再感染,其持效期远长于阿维菌素普通注射液(约为14 d)。 相似文献
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[目的]观察吡喹酮片剂、阿苯达唑干混悬剂对高原型牦牛多头蚴病的治疗效果,确定最佳剂量和用药次数。[方法]应用吡喹酮片剂按35、70 mg/kg剂量口服、阿苯达唑干混悬剂按25、50 mg/kg剂量口服治疗牦牛多头蚴病。[结果]吡喹酮片剂两个剂量的治愈率分别为72.73%和91.67%;阿苯达唑干混悬剂两个剂量的治愈率分别为81.82%和83.33%。从吡喹酮片剂35 mg/kg的剂量组死亡的2头牛检出多头蚴8个,平均感染强度2.67个;从阿苯达唑干混悬剂25 mg/kg的剂量组死亡的1头牛检出脑多头蚴2.0个,平均感染强度2个。从阳性对照组死亡的10头牛检出脑多头蚴37个,平均感染强度3.7个。[结论]吡喹酮片剂70mg/kg剂量间隔5 d三次给药达高效,适于推广应用。 相似文献
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对自然感染寄生线虫和痒螨的绵羊用爱普瑞克制剂进行驱杀疗效观察.通过虫卵和瘁螨检查确定阳性羊,设爱普瑞克0.05、0.1、0.2 mg/kg体重3个剂量组,同时设阿维菌素0.2 mg/kg体重和空白对照组,经羊皮下注射药物.结果表明,爱普瑞克按0.2 mg/kg体重和阿维菌素0.2 mg/kg体重驱杀绵羊瘁螨杀净率均达100%,寄生线虫虫卵转阴率、卵减率都达100%.而爱普瑞克0.05 mg/kg体重,0.1 mg/kg体重驱治效果差,螨虫杀净率为53%～80%,且用药后第20天瘁螨病复发;寄生线虫虫卵转阴率、卵减率只有30%～80%.0.2 mg/kg体重为爱普瑞克驱杀绵羊寄生线虫和痒螨最低有效剂量. 相似文献
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抗应激处理对肉牛引入后发病的影响 总被引：1，自引：0，他引：1
[目的]旨在探讨肉牛启运前进行抗应激处理对降低肉牛引入后发病的效果。[方法]对两批共99头牛分别进行启运前注射牛支原体灭活疫苗（第一批）与盐酸氯丙嗪（第二批）,途中运输时间分别为36 h与48 h,运输途中不给食物与饮水。牛运抵后继续观察35 d,记录发病情况。[结果]两批对照牛的平均发病率为67%。小体重组（250－300 kg）牛的发病率显著高于大体重组（300－350 kg组和350－400 kg组）发病率（P〈0.05）。虽然接种疫苗诱导产生了抗体,但接种应激加重了牛引入后发病。牛运输前肌注盐酸氯丙嗪组较对照组发病率显著降低（P〈0.05）,且0.6 mg/kg比0.3 mg/kg效果更好（P〈0.05）。[结论]启运前采用肌注盐酸氯丙嗪的抗应激处理能显著降低牛引入后的发病率。 相似文献
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[目的]观察三种不同用药方法对高原型牦牛多头蚴病的治疗效果。[方法]采用吡喹酮增量法、阿苯达唑增量法、吡喹酮和阿苯达唑联合法治疗牦牛多头蚴病。[结果]吡喹酮增量法试验组,症状消失的平均时间为8.25 d;有效率为80.9%,治愈率为72.7%;阿苯达唑增量法试验组,症状消失的平均时间为10.6 d,有效率为100%,治愈率为90.9%;吡喹酮与阿苯达唑联合法组,症状消失的平均时间为12.43 d,有效率为80%,治愈率为60%。[结论]吡喹酮增量法疗效较其它组快;阿苯达唑增量法效果缓慢,但疗效较高;联合用药法疗效欠佳。 相似文献
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Lifschitz A Nava S Guglielmone AA Imperiale F Farias C Mangold AJ Lanusse C 《Veterinary parasitology》2008,156(3-4):284-292
The therapeutic efficacies of ivermectin (subcutaneous injection) and eprinomectin (topical treatment) given at two different dosage levels to goats naturally infested with Amblyomma parvum were assessed. Treatments included subcutaneous injection of ivermectin at 0.2 and 0.4mg/kg and extra-label pour-on administration of eprinomectin at 0.5 and 1mg/kgb.w. Ivermectin and eprinomectin failed to control Amblyomma parvum on goats. Treatment with ivermectin resulted in a low number of engorged female ticks in relation to untreated control goats and, at the highest dose rate (0.4mg/kg), the female engorgement weights were significantly lower and the pre-oviposition period significantly longer than those observed in ticks recovered from untreated control goats. The tick efficacy assessment was complemented in a separate group of tick-free goats with a pharmacokinetic characterization of eprinomectin (topically administered at 0.5, 1.0 and 1.5mg/kg) and ivermectin (subcutaneous treatment given at (0.2 and 0.4mg/kg) in goats. Heparinized blood samples were taken between 0 and 21 days post-treatment. Higher and more persistent drug plasma concentrations were recovered after the subcutaneous treatment with ivermectin compared to those obtained for eprinomectin topically administered. The understanding of the relationship among the pattern of drug absorption, the kinetic disposition and the resultant clinical efficacy is relevant to improve the poor performance observed for ivermectin and eprinomectin against A. parvum on goats. 相似文献
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Anthelmintics for the control of nematode infections in the brushtail possum (Trichosurus vulpecula)
AIMS: To determine the efficacy of eprinomectin, doramectin and a combination of albendazole and levamisole in suppressing or eliminating nematode infections or faecal egg counts (FEC) in possums naturally or experimentally infected with Parastrongyloides trichosuri, Paraustrostrongylus trichosuri and Trichostrongylus colubriformis. METHODS: To establish an effective dose of eprinomectin, groups of naturally infected possums were treated with 0, 0.5, 2.5, 5.0 or 7.5 mg/kg liveweight (LW) eprinomectin pour-on (n=6 possums/group) and changes in FEC and nematode worm counts at necropsy determined, 18 days later. Efficacy of the 7.5 mg/kg dose was re-examined in a second group of naturally infected possums (n=12) by monitoring FEC weekly for 28 days post-treatment. Persistence of the anthelmintic effect of doramectin injection was tested using nematode-free possums treated with 0, 0.2, 0.4, 0.6 or 0.8 mg/kg LW (n=3 possums/ group), which were experimentally infected 14 days later with T. colubriformis, Paraustrostrongylus trichosuri and Parastrongyloides trichosuri infective larvae. Response to treatment was assessed by FEC and nematode worm counts at necropsy, 42 days posttreatment. Efficacy of a 1.0 mg/kg dose of doramectin was subsequently examined using naturally infected possums (n=11) by monitoring FEC weekly for 28 days post-treatment. To determine the efficacy of a levamisole-albendazole combination drench, possums with naturally acquired nematode infections (n=6) were treated orally with 37.5 mg/kg LW levamisole plus 23.75 mg/kg LW albendazole on 2 occasions, 7 days apart, and response to treatment was assessed by monitoring FEC for 57 days. RESULTS: Eprinomectin 7.5 mg/kg LW reduced Paraustrostrongylus trichosuri worm counts by 98 % (p<0.05). Doramectin 0.6 mg/kg LW reduced Parastrongyloides trichosuri and Trichostrongylus spp worm counts by 99% (p<0.05) and 0.8 mg/kg LW reduced Paraustrostrongylus trichosuri by 100% (p<0.05), in possums challenged with larvae 14 days after treatment. Treating possums with a levamisole-albendazole combination orally, twice, 7-days apart, reduced FEC by 99%. CONCLUSIONS: The doses of anthelmintics required to effectively control nematodes in possums were higher than those recommended for animals for which they are currently registered. Possums tolerate the high dose rates of anthelmintics used in this study without apparent adverse effects. 相似文献
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不同剂量的伊维菌素注射剂和浇泼剂对天祝牦牛牛皮蝇防制效果观察 总被引：1，自引：0，他引：1
通过对天祝县感染了牛皮蝇的牦牛的药物实验,确定了伊维菌素注射剂与浇泼剂在防治该病时的最低剂量。将280头牦牛随机分成7组,1~3组分别在颈部皮下注射0.1%伊维菌素注射液1μg/kg,5μg/kg和10μg/kg,4~6组分别沿背中线浇泼0.5%伊维菌素浇泼剂25μg/kg、50μg/kg和250μg/kg,将第7组设为空白对照。对前6组在11月份统一治疗。在第2年的3月份和5月份检查试验牦牛的背部瘤包,在治疗组牛的背部未发现瘤包,但在对照组牛的背部发现了三期幼虫。结果表明：1μg/kg伊维菌素注射剂和25μg/kg的浇泼剂对自然感染的牛皮蝇幼虫有较好的防治效果。 相似文献
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【目的】探究维生素A对牦牛卵母细胞体外成熟及后续胚胎发育能力的影响。【方法】以牦牛卵母细胞为研究对象，在其体外成熟培养液中分别添加0（对照组）、2、5、10和20 μmol/L维生素A，体外培养24 h统计第一极体排出率；对成熟后各组卵母细胞进行孤雌激活，在孤雌激活胚胎培养的第2和8天分别统计卵裂率和囊胚率；用实时荧光定量PCR检测各组MⅡ期卵母细胞中维生素A调控卵母细胞成熟典型信号通路中的节点基因RARα、RARβ、RARγ、RXRα、RXRβ、RXRγ、STRA8及非典型信号通路中的节点基因MEK和ERK1的相对表达量，筛选最佳维生素A处理浓度。在体外成熟培养液中添加最佳浓度维生素A，成熟6和24 h分别收集MⅠ和MⅡ期卵母细胞，将部分MⅡ期卵母细胞进行孤雌激活，收集激活8 d的囊胚，用实时荧光定量PCR检测GV、MⅠ和MⅡ期卵母细胞及孤雌激活囊胚中RARα、RXRα、STRA8基因的相对表达量。【结果】与对照组相比，2、5和10 μmol/L维生素A组第一极体排出率和卵裂率均显著提高（P<0.05），且2 μmol/L维生素A组均达到最高；2 μmol/L维生素A组囊胚率显著提高（P<0.05），20 μmol/L维生素A组第一极体排出率、卵裂率和囊胚率均显著降低（P<0.05）。实时荧光定量PCR结果表明，与对照组相比，2、5、10和20 μmol/L维生素A组RARα、RXRα和STRA8基因的相对表达量均显著增加（P<0.05），其中2 μmol/L维生素A组均达到最高，因此2 μmol/L维生素A对牦牛卵母细胞体外成熟的效果最好。与GV期卵母细胞相比，STRA8、RXRα、RARα基因的相对表达量在MⅡ期卵母细胞均极显著增加（P<0.01），在MⅠ及囊胚期差异均不显著（P>0.05）。【结论】在体外成熟过程中，添加2 μmol/L维生素A可以促进牦牛卵母细胞的成熟，能够显著提高孤雌激活胚胎的卵裂率，且维生素A主要通过典型信号通路调控牦牛卵母细胞的成熟。 相似文献
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[目的]为了验证纤维素复合酶饲喂肉牛的效果.[方法]选择临床健康的2岁～2.5岁的西门塔尔杂种公牛40头,按年龄、体重、相同或相近的原则,配对分为对照组和试验组,每组20头.试验组饲喂用0.1％纤维素复合酶制剂处理过的青贮玉米秸秆,对照组饲喂未处理的青贮玉米秸秆,经80 d饲喂.[结果]表明:试验组牛头均增重119.3... 相似文献
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Three groups of four lactating cows received a subcutaneous injection of 0 . 05, 0 . 10 and 0 . 15 mg Se/kg body weighty respectively administered as sodium selenate. A fourth group was injected with saline. In all the cows injected with sodium selenate, the concentration of Se in blood increased rapidly and was significantly higher than in control cows for two days in the group receiving the lowest dose and for 182 days (the duration of the experiment) in the two other groups. The activity of glutathione peroxidase in blood increased slowly in all cows injected with sodium selenate and was significantly greater than in control cows after 15, 22 and 29 days respectively, and remained significantly greater for 63, 91 and 182 days respectively. In a second experiment a single subcutaneous injection of 0 . 15 mg Se/kg body weight had no effect on the mean milk yield of 37 animals (19 . 1 kg/day) compared with the milk yield of a similar group of control animals (19 . 1 kg/day) during 70 days. The concentration of Se in milk was significantly higher on the first (168 microgram/litre) and second (69 microgram/litre) day after injection than in control animals (mean 26 microgram/litre). 相似文献
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试验选用70只健康小鼠随机分为7组,每组10只。试验1~7组分别为口服0 mg/kg胆囊收缩素（cholecystokinin,CCK）对照组、口服0 mg/kg空囊组、口服1 mg/kg CCK-卵黄抗体（yolk immunoglobulin,IgY）-低剂量微囊组、口服5 mg/kg CCK-IgY-高剂量微囊组、注射0 mg/kg CCK对照组、注射1 mg/kg CCK-IgY-低剂量非微囊组、注射3 mg/kg CCK-IgY-高剂量非微囊组。单笼饲养,试验期40 d。以小鼠体重、日采食量及血液中CCK抗体D值为评价指标,对CCK-IgY及其微胶囊进行促生长及免疫效果比较研究。结果表明,从试验全期来看,试验3组平均体重和平均日采食量均极显著高于试验4组（P<0.01）,但与试验1组相比差异不显著（P>0.05）;随着注射CCK-IgY剂量的增加,D值也随之升高,试验7组D值极显著高于试验5组（P<0.01）,而CCK-IgY微囊组均未达到与注射一致的效果。口服微囊化CCK-IgY和腹腔注射非微囊化CCK-IgY均可刺激机体产生相应的免疫应答反应,腹腔注射非微囊化CCK-IgY具有较明显的促生长效果,但CCK-IgY微囊饲喂效果不够明显,需进一步研究。 相似文献