共查询到20条相似文献，搜索用时 62 毫秒
1.
为了确定鸽Ⅰ型副黏病毒(S-1株)灭活疫苗的保存期，对不同温度下保存不同时间的3批鸽Ⅰ型副黏病毒(S-1株)灭活疫苗实验室制品的物理性状、安全性和免疫效力进行了检测。试验结果表明，该疫苗冷藏(2～8℃)保存12个月、室温(25℃左右)保存6个月，其物理性状、安全性和免疫效力无明显变化，均能达到《鸽Ⅰ型副黏病毒(S-1株)灭活疫苗质量标准》的要求。因此，在《鸽Ⅰ型副黏病毒(S-1株)灭活疫苗制造及检验试行规程》中规定该疫苗的保存期为：冷藏(2～8℃)保存，保存期为12个月。 相似文献
2.
3.
4.
为了弄清含硒型牛副伤寒活疫苗及其专用稀释液的最佳保存条件及保存期,将四批含硒型牛副伤寒活疫苗(批号200001、200101、200102、200201)分别置-20℃、0～4℃、15～21℃保存不同时间后,检查其活菌率及其对豚鼠的免疫效力;同时用3批含硒型牛副伤寒活疫苗专用稀释液(批号200101、200201、200202)分别置室温(15～21℃)下保存不同时间后,检查其物理性状及灭菌状态.结果显示,这四批疫苗于-20℃保存24个月、0～4℃保存12个月、15～21℃保存2个月,活菌率均在80%以上,对豚鼠的免疫效力均合格;同时这三批含硒型牛副伤寒活疫苗专用稀释液于15～21℃保存12个月外观物理性状及无菌检验均合格.因此,含硒型牛副伤寒活疫苗保存期暂定为-20℃ 24个月、0～4℃ 12个月、15～21℃ 2个月;保存专用稀释液15～21℃(室温)保存期暂定为12个月. 相似文献
5.
猪链球菌（ST171）活疫苗—15℃保存期试验 总被引：1，自引：1，他引：0
我国现行兽用生物制品规程 (以下简称《规程》) [1]规定 ,猪链球菌活疫苗在 2～ 8℃环境中 ,保存期为 1 2个月。本试验对保存于 - 1 5℃环境中 1 9～ 40个月的猪链球菌活疫苗进行活菌计数及效力、安全性测定 ,均能达到《规程》标准。1 材料和方法1 .1 猪链球菌活疫苗 用本厂 相似文献
6.
7.
规程规定新城疫苗低温保存三个月后应以鸡胚测定效力,必须达10~(-5)稀释度全死,方可出厂,去年曾进行测定两批[第七批,第批均未达到及格标准,制造单位认为10~(-5)全死似较还严要 相似文献
8.
9.
为探索冻干剂、咀嚼剂和喷剂三种剂型的rAd5-ΔE1/E3-CGS狂犬病口服疫苗在运输、保存、反复冻融及不同温度下投放时疫苗效价的消减规律，将三种剂型的疫苗经过2～8℃运输48 h,重新入库的疫苗分别-20℃保存1年和反复冻融5次，再将冻融后疫苗分别于2～8℃保存4个月、15℃放置1个月、25℃放置1周和37℃放置3 d,于不同时间点取样检测疫苗效价(lgTCID50/头份)。结果显示，三种口服疫苗经过2～8℃运输48 h后，效价分别下降至6.25、5.75和6.25,再经过-20℃保存1年和反复冻融5次后效价分别下降至5.67、5.33、5.33和5.33、5.00、5.67。在2～8℃保存4个月后，三种剂型口服疫苗效价均能达到5.00以上；在15℃放置1个月、25℃放置1周以及在37℃放置3 d后，疫苗效价最低分别为3.75、2.50和1.00。研究表明，三种剂型口服疫苗在冷链运输、冷冻保存、反复冻融和低温环境释放条件下具有良好的稳定性，常温环境对咀嚼剂的稳定性影响较小，高温环境会严重降低口服疫苗效价，建议在气温不高于15℃条件下进行rAd5-ΔE1/E3-C... 相似文献
10.
11.
Beran GW 《Preventive veterinary medicine》2008,86(3-4):198-207
When early people made their appearance, zoonotic infectious diseases were already waiting, but epidemic diseases did not appear in human history until people began to live in large numbers under conditions of close contact, mainly during the last 10,000 years. Disease has decimated urban populations, conquered armies, and disrupted society. The focus here is on (1) the plague of Athens and the Black Death; (2) smallpox, influenza, and rabies; (3) avian influenza prion diseases, and foot & mouth disease; and (4) emerging and re-emerging diseases. All have veterinary public health associations. In Athens, Greece, in 430 BC, when the Spartans ravaged the countryside, hordes crowded into Athens so that orderly movements, space in which to live, and adequate supplies of food became impossible. Crowding of any population fosters disease transmission; chaos and disorder enhance it all the more. Out of northern Egypt came a terrible plague from across the Mediterranean Sea. The identity of the plague of Athens remains unsure, but the well-considered conclusion is Rift Valley Fever, a mosquito borne, viral zoonosis. The Black Death, also called the Plague, raged in Asia for centuries. In 1347, the Black Death was brought by a ship out of Asia to Sicily. The scenes of devastation were repeated throughout Europe, with 90% or more of the people dying in city after city. Influenza, too, has been a cause of periodic human epidemics, but the great pandemic of influenza occurred in the last months of World War I. In the years of highest occurrence, more than half the world's population became clinically infected. If veterinary public health had been born earlier, it could have led to elucidating the epidemiology of influenza and the plagues of Athens, Europe, and Asia. In turn, smallpox had also caused continual tragedy. In 1796, Edward Jenner began to harvest pustules of cowpox from children or infected cows and inject them into susceptible children. In 1980, the World Health Organization declared that smallpox had been eliminated from the world. Rabies, though, still strikes terror. A number of animal diseases, broadly termed emerging and re-emerging diseases, need surveillance because they have the potential to impact human health. From late in 2003 to 2007, the highly pathogenic H5N1 influenza virus in poultry infected at least 121 people and caused 62 deaths in four countries. The prion diseases, too, all have very high numbers in concentrated contacts. To control these diseases, veterinary public health is essential, with diagnosis, epidemiological surveillance, clinical manifestations, and prevention as primary measures. 相似文献
12.
13.
Dekker A Dercksen D Snoep J van Wuyjckhuise L 《Tijdschrift voor diergeneeskunde》2007,132(18):695-701
On 26th of july 2007 a new case of bluetongue was notified in the Netherlands and on 2nd of august 2007 foot-and-mouth disease was diagnosed in Surrey, England, which raised the threat of having both infections simultaniously in one area. Bluetongue and foot-and-mouth disease have a different pathogenesis, but symptoms may resemble each other at a later stage of infection. The pathogenesis and possible clinical symptoms of both infections are discussed and illustrated with pictures. 相似文献
14.
15.
在动物的异常行为中以刻板行为最为常见,而咽气癖又是马最常见的口部刻板行为之一。作者就咽气癖在生理方面和心智方面对马体产生的影响、行为基础、诱因的研究进展及常见的防治措施进行综述。 相似文献
16.
17.
18.
近几年,世界饲用添加剂市场增长较快,预计今后将进一步增长,据世界粮农组织(FAO)首领会议的倡议,到2015年,将使世界营养不良的人口削减一半,其间,肉制品将会以每年2％的速度增长,特别是加快猪肉和禽肉增长。这将促进世界添加剂,尤其是蛋氨酸和赖氨酸需求量的增加。 相似文献
19.
20.