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1.
Turnera ulmifolia is a plant popularly known in Brazil and South America as chanana. Some species of Turnera are widely used in folk medicine for different types of inflammatory diseases. In this study, the preventive intestinal antiinflammatory activity of a lyophilized infusion obtained from the aerial parts of T. ulmifolia was tested in the trinitrobenzenesulphonic acid (TNBS) model of rat colitis. The results obtained revealed that pretreatment to colitic rats with the extract, at 250 and 500 mg/kg, significantly attenuated the colonic damage induced by TNBS. This beneficial effect was associated with an improvement in the colonic oxidative status, since the infusion prevented the glutathione depletion that occurred as a consequence of the colonic inflammation. On the other hand, this antioxidant activity was confirmed in in vitro studies. In conclusion, the preventive effect exerted by the lyophilized infusion of T. ulmifolia in the TNBS model of rat colitis is probably related to its antioxidant properties, due to its flavonoids content.  相似文献   

2.
We studied the activity of urease in soils of Castanopsis cuspidata, Quercus serrata, and Chamaecyparis obtusa forests in western Japan to determine why succession of ammonia fungi takes place synchronously on soils treated simultaneously with the same level of urea among different vegetation types regardless of the time of year that the treatments are conducted. The activity was determined by the amount of urea remaining after urea addition and incubation on three soil layers, O, A, and B, on nine occasions. As a result, we found that the activity was significantly the highest in the O layer, that it did not differ according to vegetation type, and that it did not change through sampling occasions. The results indicate that the O layer is strongly implicated in generating favorable conditions for ammonia fungus proliferation by its overwhelming ability to decompose urea to ammonia. In soils treated simultaneously with urea, it appears that the ammonium-N concentration increases in similar patterns among different types of vegetation and at different times of the year.  相似文献   

3.
The methanol extract of Leucas aspera flowers, its fractions, the alkaloidal residue and the expressed flower juice, tested for antimicrobial activity, showed good antibacterial activity for methanol extract and methanol fraction with maximum activity for the alkaloidal residue.  相似文献   

4.
Antioxidant activity of Litsea cubeba   总被引:5,自引:0,他引:5  
Hwang JK  Choi EM  Lee JH 《Fitoterapia》2005,76(7-8):684-686
The antioxidant activity of Litsea cubeba was studied in terms of three different assay systems: DPPH assay, peroxidase/guaiacol assay, and TBA test. The L. cubeba methanol extract and its fractions showed remarkable antioxidant activity in comparison with alpha-tocopherol and ascorbic acid.  相似文献   

5.
Using affinity chromatography, SDS-PAGE, peroxidase activity assay and mass spectrometry data, a new extracellular peroxidase (CMP) from Chelidonium majus milky sap was isolated and characterized. The protein has a molecular weight of about 40 kDa and belongs to secretory class III plant peroxidases. The peroxidase activity is also accompanied by DN-ase activities. A novel CMP combined with other proteins is probably involved in development and differentiation of the plant and defence against different pathogens. It suggests that the biological activity of C. majus whole plants and extracts may depend not only on its alkaloidal content but also on the presence of biologically active proteins.  相似文献   

6.
Amanlou M  Fazeli MR  Arvin A  Amin HG  Farsam H 《Fitoterapia》2004,75(7-8):768-770
The methanolic extract of the aerial parts of Satureja khuzistanica was investigated for its antimicrobial activity. The maximum antibacterial and antifungal activities were observed against Staphylococcus aureus and Candida albicans.  相似文献   

7.
Khan MR  Omoloso AD 《Fitoterapia》2008,79(5):370-373
The Breynia cernua leaves, stem and root barks and heart-woods extracted with petrol, dichloromethane, ethyl acetate, butanol and methanol gave fractions with varied level of antimicrobial activity. The best activity was exhibited by the methanol extract of the root bark followed by its butanol fraction. These were the only fractions exhibiting a good level of antifungal activity as compared to the standard. The dichloromethane fraction of the stem bark also demonstrated good activity.  相似文献   

8.
The essential oil of fresh leaves of Lippia aff. gracillis was analyzed by GC/MS and evaluated for its antibacterial effects. The results showed a moderate antibacterial activity and confirm the traditional uses of L. aff. gracillis.  相似文献   

9.
Liu H  Yang X  Ren T  Feng Y  Xu H 《Fitoterapia》2005,76(7-8):666-670
Antioxidant activity of the ethanol extract of Erigeron breviscapus (EEEB) were studied by using neuron oxidative injury model induced by superoxide radical. EEEB at the dose of 10-140 mug/ml reduced significantly the lipid peroxidation levels and lactic dehydrogenase (LDH) release from neuron exposed to superoxide radical (generated by xanthine and xanthine oxidase). These results suggest that neuroprotective actions of EEEB may be due to its antioxidant or radical scavenging activity.  相似文献   

10.
Naik SR  Panda VS 《Fitoterapia》2008,79(6):439-445
The protective effects of Ginkgoselect Phytosome((R)) (GBP) on Rifampicin (RMP) induced hepatotoxicity and the probable mechanism(s) involved in this protection were investigated in rats. Liver damage was induced in Wistar rats by administering rifampicin (500 mg/kg, p.o.) daily for 30 days. Simultaneously, GBP at 25 mg/kg and 50 mg/kg, and the reference drug silymarin (100 mg/kg) were administered orally for 30 days/daily to RMP treated rats. Levels of marker enzymes (SGOT, SGPT and SALP), albaumin (Alb) and total proteins (TP) were assessed in serum. The effects of GBP on lipid peroxidation (LPO), reduced glutathione (GSH), superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPX) and glutathione reductase (GR) were assayed in liver homogenates to evaluate antioxidant activity. GBP (25 and 50 mg/kg) and silymarin elicited a significant hepatoprotective activity by lowering the levels of serum marker enzymes and lipid peroxidation and elevated the levels of GSH, SOD, CAT, GPX, GR, Alb and TP in a dose dependant manner. The present findings suggest that the hepatoprotective effect of GBP in RMP induced oxidative damage may be related to its antioxidant and free radical scavenging activity.  相似文献   

11.
The essential oil of Achillea clavennae was investigated for its antibacterial activity against some respiratory tract pathogens. Maximum activity was observed against Klebsiella pneumoniae and penicillin-susceptible and penicillin-resistant Streptococcus pneumoniae. The oil also exhibited strong activity against Gram (-) Haemophilus influenzae and Pseudomonas aeruginosa. Gram (+) Streptococcus pyogenes was the most resistant to the oil.  相似文献   

12.
Bose A  Mondal S  Gupta JK  Ghosh T  Dash GK  Si S 《Fitoterapia》2007,78(7-8):515-520
Oral administration of the ethanolic extract (200 and 400 mg/kg, p.o) and its fractions (200 mg/kg each) of the aerial parts of Cleome rutidosperma produced significant analgesic activity in acetic acid-induced writhing and tail immersion tests, anti-inflammatory effect against carrageenin induced inflammation and adjuvant induced polyarthritis and antipyretic activity against yeast-induced pyrexia. Fractionation of the ethanolic extract potentiated the activities.  相似文献   

13.
The insecticidal activity of crude essential oil extracted from Cymbopogon schoenanthus and of its main constituent, piperitone, was assessed on different developmental stages of Callosobruchus maculatus. Piperitone was more toxic to adults with a LC(50) value of 1.6 microl/l vs. 2.7 microl/l obtained with the crude extract. Piperitone inhibited the development of newly laid eggs and of neonate larvae, but was less toxic than the crude extract to individuals developing inside the seeds.  相似文献   

14.
The essential oil of Oliveria decumbens was investigated for its components and antimicrobial activity against six bacteria and two fungal strains. The essential oil was characterized by a high amount of oxygenated monoterpene components of which thymol (47.06%) and carvacrol (23.31%) were the major components. The oil exhibited high antimicrobial activity against all tested Gram+ and Gram- bacteria and fungal strains.  相似文献   

15.
Chauhan AS  Negi PS  Ramteke RS 《Fitoterapia》2007,78(7-8):590-592
Seabuckthorn (Hippophae rhamnoides) seeds aqueous extract was screened for antioxidant and antibacterial activities. The antioxidant activities (reducing power, DPPH and liposome model system) showed a good antioxidant activity. The extract was also found to possess antibacterial activity with a MIC values with respect to Listeria monocytogenes and Yersinia enterocolitica found to be 750 and 1000 ppm, respectively. The antioxidant and antimicrobial effects of the extract implicate its potential for natural preservation.  相似文献   

16.
Studies assessing the characteristics of active ingredients (AIs) of toxic baits for leaf-cutting ants are still scarce, although the need for a delayed action of these compounds on adult workers has been well accepted (mortality ≤15% at 24 h and ≥90% at 21 days). Therefore, we determined the insecticidal action of two AIs used in commercial baits, diflubenzuron and dechlorane, over time in workers, and discussed the control of colonies in relation to the existing literature. Dechlorane presented excellent insecticidal activity with a delayed action at all concentrations tested, although its commercial use has been prohibited due to its organochlorine nature. In contrast, diflubenzuron did not cause significant mortality or symptoms of intoxication, indicating that the successful cases reported with the use of baits containing this AI were in fact due to an accidental contamination with dechlorane. We comment about the ineffectiveness of diflubenzuron on alternative targets, i.e., young forms and the mutualistic fungus, supporting the concept that the AI needs to a have a delayed action on adult workers.  相似文献   

17.
目的]印度黄檀叶含有多酚及类黄酮物质,研究印度黄檀叶多酚及其抗氧化活性,可为其利用提供依据。[方法]以印度黄檀叶为原料,乙醇为提取液,经单因素实验与正交试验设计,检测在不同乙醇浓度、提取时间、提取温度及超声功率120 w时3个因素进行响应面优化试验,确定印度黄檀多酚的提取工艺;同时,鉴定印度黄檀叶乙醇-水提取液对DPPH-自由基的清除能力。[结果]低浓度印度黄檀叶多酚能发挥更强的抗氧化能力,其提取液对清除DPPH自由基的半数抑制质量浓度(IC_(50))约为3.2 mg·L~(-1),略大于Vc的2.5 mg·L~(-1);不过,其还原能力略低于Vc。[结论]印度黄檀叶内富含多酚类物质,具有很强的体外抗氧化活性,可作为天然抗氧化植物资源开发利用。  相似文献   

18.
Fluconazole resistance is becoming an important clinical concern. We studied the in vitro effects of cinnamaldehyde against 18 fluconazole-resistant Candida isolates. MIC90 of cinnamaldehyde against different Candida isolates ranged 100–500 μg/ml. Growth and sensitivity of the organisms were significantly affected by cinnamaldehyde at different concentrations. The rapid irreversible action of this compound on fungal cells suggested membrane-located targets for its action. Insight studies to mechanism suggested that cinnamaldehyde exerts its antifungal activity by targeting sterol biosynthesis and plasma membrane ATPase activity. Inhibition of H+-ATPase leads to intracellular acidification and cell death. Toxicity against H9c2 rat cardiac myoblasts was studied to exclude the possibility of further associated cytotoxicity. The observed selectively fungicidal characteristics against fluconazole-resistant Candida isolates signify a promising candidature of this essential oil as an antifungal agent in treatments for candidosis.  相似文献   

19.
Sasikumar JM  Doss PA 《Fitoterapia》2006,77(7-8):605-607
Methanol extract of Rhaphidophora pertusa stem was analyzed for its antioxidant (DPPH, reducing power and Fe(3+) metal chelation methods) and antibacterial activities. The extract was found effective against the three antioxidant test models and exhibited strong and moderate antibacterial activity against the tested pathogenic bacteria.  相似文献   

20.
Casearia sylvestris methanolic extract (MCE) was screened at doses of 125–500 mg/kg for its antihyperlipidemic activity. The antihyperlipidemic effect was evaluated in olive oil-loaded mice. Acute treatment caused inhibition in the triglyceride (TG) and serum lipase elevation-induced by 5 ml/kg of olive oil.  相似文献   

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