共查询到19条相似文献，搜索用时 218 毫秒
1.
动脉血气分析评价几种麻醉方法对马呼吸功能的影响 总被引：3，自引：0，他引：3
以动脉血气分析做为手段，对静松灵、水合氯醛、激光三种麻醉方法进行评价，激光麻醉对实验马血气及酸碱值没有显著影响；静松灵（１ｍｇ／ｋｇ体重，ｉｍ）和水合醛（１２ｇ／１００ｋｇ体重，ｉｖ）都能使ＰＯ２、Ｓａｔ．Ｏ２，Ｃ－Ｏ２等显著下降，但水合氯醛出现较早，在注射在３０至６０ｍｉｎ时最低；而静松灵出现较晚，以注射后６０－９０ｍｉｎ显著，但都未构成低氧血症，更未达呼吸衰竭。此外，静松灵对ＰＨ，Ｔ－ＣＯ２， 相似文献
2.
通过对１１匹实验马的血气、酸碱值分析，结果表明以１２ｇ／１００ｋｇ体重的水合氯醛麻醉后，实验马的Ｐｏ２、Ｓａｔ·Ｏ２、Ｃ－Ｏ２三项指标均显著降低，ＰＡ－ａＤＯ２显著增加；而ｐＨ、Ｐｃｏ２、Ｔ－ＣＯ２、ＡＢ、ＳＢ、ＢＥｂ六项指标无显著变化。说明该剂量的水合氯醛对马的呼吸功能有一定影响，且主要影响与氧有关的指标。 相似文献
3.
对３头实验性肠阻塞驴和１０匹自然肠阻塞马、骡进行了血气分析。结果表明：（１）实验性肠阻塞驴在造型后２４小时，血液ｐＨ、ＰＯ２、ＰＣＯ２、Ｏ２Ｓ比造型前略低（Ｐ＞０．０５），ＨＣＯ－３、ＴＣＯ２、ＢＥ、ＳＢＥ、ＳＢＣ比造型前明显低（Ｐ＜０．０５，Ｐ＜０．００１），治愈时血气指标趋于正常；（２）自然肠阻塞马、骡在接受治疗前，上述９项血气指标变化与实验性肠阻塞（造型后２４小时）驴大致相同，治疗后２４小时，马、骡的绝大多数血气指标呈继续下降趋势，治愈时血气指标亦趋于正常。 相似文献
4.
对３头实验性肠阻塞驴和１０匹自然肠阻塞马，骡进行上血气分析。结果表明：１．实验性肠阻塞驴在造型后２４小时，血流ｐＨ，ＰＯ２，ＰＣＯ２，Ｏ２Ｓ比造型前略低于，ＨＣＯ＾－３，ＴＣＯ２，ＢＥ，ＳＢＥ，ＳＢＣ比秸莳有明显低，治愈时血气指标趋于正常；２．自然肠阻塞马，骡在接受治疗前，上述９项血气指标变化与实验性肠阻塞驴大致相同，治疗后２４小时马骡的绝大多数血气指标呈继续下降趋势，治愈时血气指标亦趋于正常。 相似文献
5.
类固醇激素对牛输卵管上皮细胞分泌的调节及其分泌物对小鼠胚胎发育的影响 总被引：1，自引：0，他引：1
模拟发情期（０～６ｄ）母牛外周血浆雌激素和孕酮变化水平，在添加相应水平１７β－雌二醇和孕酮的ＴＣＭ－１９９液中，培养间情期牛输卵管上皮细胞（ＢＯＥＣ）。５％ＳＤＳ－ＰＡＧＥ分析ＢＯＥＣ分泌物，发现上皮细胞受类固醇激素作用分泌的２类蛋白质分子量与自然发情期（０～６ｄ）分泌的特异蛋白相似。证明类固醇激素可以调节和启动间情期ＢＯＥＣ的分泌活动。当雌二醇浓度高达１ｍｇ／Ｌ时，即使不加孕酮，ＢＯＥＣ仍能分泌这２类蛋白质。在培养小鼠原核胚的ＣＺＢ培养液内添加牛输卵管上皮细胞分泌蛋白（ＢＯＥＰ），与添加间情期牛输卵管冲洗蛋白（ＢＯＰ）和小牛输卵管冲洗蛋白（ＣＯＰ）相比，能显著提高通过２－细胞阶段胚胎的百分率和桑囊形成率，表明ＢＯＥＰ能较好地促进胚胎的分裂和发育。但ＢＯＥＰ组的桑囊形成率显著低于对照组，表明ＢＯＥＰ中可能缺少某些低于Ｍｒ１．０×１０４的蛋白因子的协调作用，以及含有Ｍｒ３．０×１０４～５．６×１０４的分泌蛋白的抑制作用而阻碍胚胎分裂与发育。 相似文献
6.
马立克氏病病毒感染雏鸡的SOD活性变化 总被引：8，自引：4，他引：4
１日龄肉用ＡＡ雏鸡被马立克氏病病毒（ＭＤＶ）强毒人工感染后，马立克氏病（ＭＤ）发病率６２％，死亡率３４％；脾脏、胸腺、法氏囊、心脏、肝脏、肾脏和性腺超氧化物歧化酶（ＳＯＤ）活性与健康雏鸡相比，Ｔ－ＳＯＤ和Ｍｎ－ＳＯＤ活性均有显著降低（Ｐ＜０．０５），而Ｃｕ，Ｚｎ－ＳＯＤ活性无显著变化（Ｐ＞０．０５）。 相似文献
7.
给ＢＡＬＢ／ｃ鼠注射南美响尾蛇毒液后１ｈ，接种人血清白蛋白（ＨＳＡ）或鸡卵白蛋白（ＯＶＡ），或者作２，４－二硝基氟苯（ＤＮＦＢ）皮肤涂捕敏感试验，发现响尾蛇毒液导致抗ＯＶＡ和抗ＨＳＡ的抗体ＩｇＧ水平显著降低。对响尾蛇毒素（毒液中一种主要的神经毒成分）的酸性无毒亚单位Ａ（ＣＡ）或碱性磷脂酶Ａ２（ＣＢ）进行研究表明，完整的响尾蛇毒素分子能导致抗ＯＶＡ和抗ＨＳＡ的抗体ＩｇＧ水平显著降低，但ＣＡ葆ＣＢ均不 相似文献
8.
采用四种方法：即①单克隆抗体检测抗原的酶联免疫吸附试验（Ａｇ－ＥＬＩＳＡ）②检测抗体的酶联免疫吸附试验（Ａｂ－ＥＵＳＡ）③表膜检查（ＢＣＥ）④小白鼠接种（ＭＩ），检查了肯尼亚１８３头骆驼锥虫的循环抗原，ＢＣＥ查出３７头阳性２０％），ＭＩ６０头阳性（３３％），Ａｇ－ＥＬＩＳＡ６３头阳性（３４％），Ａｂ－ＥＬＩＳＡ检出９０头阳性（４９％）。其中ＢＣＥ未能检出的２４头中，Ａｇ－ＥＬＩＳＡ检出１８头（７５％）。所有阳性头数中，Ａｇ－ＥＬＩＳＡ检出９３％，Ａｂ－ＥＬＩＳＡ９５％。根据５５头的结果，阳性与阴性之间Ａｇ－ＥＬＩＳＡＯＤ值差异极显著（Ｐ＜０．０００１），Ａｂ－ＥＬＩＳＡＯＤ值差异不显著。因此，用Ａｇ－ＥＬＩＳＡ或结合ＢＣＥ诊断伊氏锥虫感染比用ＡＢ－ＥＬＩＳＡ更理想。 相似文献
9.
下丘脑是动物食欲调节的中枢，外周食欲信号在下丘脑中经食欲调节网络整合，产生饱感或饥饿。其中，以 ５′－磷酸腺苷激活的蛋白激酶（ＡＭＰＫ）调控位点上的 ＡＭＰＫ-ＡＣＣ-ＣＰＴ１和 ＵＣＰ２-ＦＯＸＯ１-ｐＣＲＥＢ信号通路以及雷帕霉素靶蛋白（ｍＴＯＲ）调控位点上的 ＰＩ３Ｋ-Ａｋｔ-ｍＴＯＲ和 ｍＴＯＲ-４ＥＢＰ１／ｐ７０Ｓ６Ｋ-ＮＰＹ／ＡｇＲＰ信号通路尤为重要。ＡＭＰＫ和 ｍＴＯＲ在 ＡＭＰＫ-ＴＳＣ ｍＴＯＲ通路、固醇类调节因子绑定蛋白（ＳＲＥＢＰ）基因表达和吞噬启动激酶（Ｕｌｋ１）活性通路上存在互作。外周营养和能量信号传输到下丘脑后，经过这些网络的传输和分析，作用于下丘脑中的食欲相关肽，最终调控动物的采食行为。 相似文献
10.
11.
12.
Feeding practice and influence on selected blood parameters in show jumping horses competing in Switzerland 
下载免费PDF全文
下载免费PDF全文 J. Brunner A. Liesegang S. Weiss B. Wichert 《Journal of animal physiology and animal nutrition》2015,99(4):684-691
The aim of this study was to compare the nutritional management of show jumping horses in practice with recommendations from the literature. Additionally, the effects of these feeding practices on several blood metabolic parameters before and after exercise were studied. Blood samples were collected in the field from 27 different horses at 71 trials on the level M1 to S2 show jumping competitions in Switzerland and questionnaires on feeding practice of the studied horses were evaluated. The questionnaires revealed that during training and on tournament days horses received on average 3.1 kg of concentrate per day (min. 2.0 kg, max. 6.6 kg) divided into two to three meals. The horses were fed on average 6.9 kg of roughage per day (min. 4.0 kg, max. 13.0 kg). Additionally, it was observed that the horses received the last meal on average 6 h 10 min (min. 1 h 50 min, max. 12 h 30 min) before the start of the first show jumping turn, respectively, 7 h 30 min (min 1 h 50 min, max. 13 h 0 min) before the second turn. Seven horses (35%) had access to hay waiting in the trailer between two turns. The statistical analysis revealed no significant influence of the concentrate feeding time point on lactate, triglyceride and insulin levels, but a significant influence on free fatty acids (FFA) and blood glucose concentrations. Roughage feeding of the show jumping horses 2–4 h prior to exercise revealed the most remarkable changes in blood parameters during the show jumping course. These results received under field conditions should be approved in future under standardized conditions. 相似文献
13.
V. L. H. ROBERTS S. A. McKANE A. WILLIAMS D. C. KNOTTENBELT 《Equine veterinary journal》2009,41(2):165-170
Reasons for designing and reporting technique: Idiopathic headshaking has remarkable similarities to human neuropathic facial pain syndromes associated with post herpetic and trigeminal neuralgia. These derive from abnormal sensory function within the peripheral or central pathways of the trigeminal nerve (TgN). Limiting input from the TgN can be helpful in controlling the perception of pain. Rhizotomy of the infraorbital branch of the TgN as it emerges from the infraorbital canal has been reported but has a poor efficacy. A novel technique involves compression of the nerve at a more caudal location within the infraorbital canal and the technique requires validation. Hypothesis: Caudal compression of the infraorbital nerve with platinum coils, performed in horses diagnosed with idiopathic headshaking, results in a decrease in clinical signs. Methods: Caudal compression of the infraorbital nerve, using platinum embolisation coils, was performed under fluoroscopic guidance. Clinical records of 24 idiopathic headshakers that had undergone this procedure were reviewed. Follow‐up information was obtained by telephone questionnaire with the owner or referring veterinary surgeon. Results: All 24 horses had at least one surgical procedure. Median follow‐up time was 6 months. There were 2 horses which had surgery 2 weeks before follow‐up and these were excluded from the analysis of outcome. Following one surgery, 13/22 horses (59.0%) had a successful outcome. Of the 9 horses that did not improve, surgery was repeated in 6 cases. Two of these horses had a successful outcome. Overall, a successful outcome was obtained in 16/19 horses (84.2%). Conclusions: This surgical technique is likely to prevent input from the TgN at a more caudal location then the previously described infraorbital neurectomy. The technique requires refinement. 相似文献
14.
J Schumacher J S Spano H D Moll 《Journal of the American Veterinary Medical Association》1985,186(12):1301-1303
Peritoneal fluid was collected from 15 clinically normal horses and was analyzed for nucleated cell (NC) counts and specific gravity. Six horses (controls, group 1) were subjected to abdominocentesis only, with a teat cannula, every 24 hours for 5 days. There were no marked changes in the peritoneal fluid of these horses over the 5-day period. Peritoneal fluid was collected from 6 other horses (group 2) with an 8.89-cm 18-gauge needle. The needle was then advanced until intestinal fluid was obtained. Peritoneal fluid was then collected with teat cannulas at 24-hour intervals for an additional 4 days. Peritoneal fluid NC counts from group 2 horses were significantly increased (P less than 0.05) at peak values 2 days after enterocentesis. Specific gravities of peritoneal fluid from group 2 horses were increased on days 1 and 2 after enterocentesis (P greater than 0.05). Peritoneal fluid from 3 other horses (group 3) was collected before enterocentesis (base line) and again at 4-hour intervals after enterocentesis. Peritoneal fluid NC counts of group 3 horses were markedly increased above base-line values 4 hours after enterocentesis and continued to increase for up to 12 hours after enterocentesis when the experiment was terminated. All horses that underwent enterocentesis remained clinically normal except 1 group 3 horse that had a fever (39.6 C) 24 hours after enterocentesis. 相似文献
15.
Escribano BM Agüera EI Rubio MD Santisteban R Vivo R Agüera S Tovar P 《Research in veterinary science》2011,91(3):e144-e148
We hypothesized that the information obtained from a discriminant analysis could be used to objectively discriminate horses untrained from early ages, in agreement with certain physiological characteristics.In the biopsies of 24 Spanish Pure Bred horses (1.5–3 years old) before and after a standardized exercise test (SET; 4–7 m/s with a change of velocity of 1 m/s every 2 min) muscle enzymes, substrate and metabolites were determined. Also, diverse plasma and blood parameters were considered.Three pre-exercise groups (A1: six horses; A2: seven horses and A3: eleven horses) and two post-exercise groups (B1: sixteen horses; B2: eight horses) were defined from a correspondence analysis. Forward stepwise discriminant analysis selected 11 variables which differentiated the groups between each other both pre- and post-exercise.The results of the present study suggested the utility of a discriminant analysis to categorize horses in agreement with certain physiological variables. It could be used for establishing different types of training in each group by expert trainers. 相似文献
16.
R K Schneider L R Bramlage L M Mecklenburg R M Moore A A Gabel 《Equine veterinary journal》1992,24(6):443-449
Open drainage was used to treat 26 horses with persistent or severe septic arthritis/tenosynovitis. Infected synovial structures were drained through a small (3 cm) arthrotomy incision that was left open and protected by a sterile bandage. Joint lavage was performed in all 26 horses. In addition to systemic antibiotics, 23 of these horses were also treated with intra-articular antibiotics; amikacin (17 horses), gentamycin (2 horses), cefazolin (2 horses), and 2 horses were injected at different times with gentamycin and amikacin. The infection was eliminated from the involved synovial structures in 25 of 26 horses; 24 survived and were released from the hospital. The arthrotomy incisions healed by granulation in 16 horses; in 9 horses the arthrotomy incision was sutured closed once the infection was eliminated. Seventeen horses returned to soundness and resumed athletic function. Open drainage was an effective method of achieving chronic drainage from a joint or tendon sheath. It is indicated in horses that have established intra-synovial infections or in horses that do not respond to joint lavage through needles. 相似文献
17.
D W Horohov A Dimock P Guirnalda R W Folsom K H McKeever K Malinowski 《American journal of veterinary research》1999,60(5):643-647
OBJECTIVE: To compare exercise-induced immune modulation in young and older horses. ANIMALS: 6 young and 6 aged horses that were vaccinated against equine influenza virus. PROCEDURE: Venous blood samples were collected for immunologic assessment before and immediately after exercise at targeted heart rates and after exercise for determination of plasma lactate and cortisol concentrations. Mononuclear cells were assayed for lymphoproliferative responses and incubated with interleukin-2 (IL-2) to induce lymphokine-activated killer (LAK) cells. Antibodies to equine influenza virus were measured. RESULTS: Older horses had significantly lower proliferative responses to mitogens than younger horses prior to exercise. Exercise caused a significant decrease in lymphoproliferative response of younger horses, but not of older horses. Activity of LAK cells increased slightly with exercise intensity in younger horses. Cortisol concentrations increased in both groups after exercise; younger horses had higher concentrations after exercise at heart rates of 180 and 200 beats/min than those of older horses. Plasma lactate concentrations increased with exercise intensity but there were no differences between older and younger horses. Older horses had lower antibody titers to equine influenza virus than younger horses. Exercise did not affect antibody titers. CONCLUSION: Although lymphoproliferative responses and antibody titers of older horses were less than those of younger horses, older horses were more resistant to exercise-induced changes in immune function, possibly because of lower cortisol concentrations. CLINICAL RELEVANCE: Stress and aging are known to affect immune function. Older horses had reduced immune function, but were more resistant to exercise-induced immune suppression than younger horses. 相似文献
18.
Effects of furosemide on the racing times of Thoroughbreds 总被引：1，自引：0，他引：1
C R Sweeney L R Soma A D Maxson J E Thompson S J Holcombe P A Spencer 《American journal of veterinary research》1990,51(5):772-778
The effects of furosemide on the racing times of 79 horses without exercise-induced pulmonary hemorrhage (EIPH) and 52 horses with EIPH were investigated. Racing times were adjusted to 1-mile equivalent racing times by 2 speed handicapping methods, and analysis of covariance was used to adjust actual racing times by winning time and distance for each race. All 3 methods of determining racing time indicated that geldings without EIPH had significantly faster racing times (P less than 0.05) when given furosemide before racing than when furosemide was not given before racing. Females and colts without EIPH were determined to have faster racing times when furosemide was given before racing, but the difference was not significant. Geldings with EIPH had significantly faster racing times (P = 0.0231) when given furosemide before racing, as determined by one of the speed handicapping methods. There was a strong correlation (range 0.9314 to 0.9751) between the 1-mile equivalent racing times, as determined by the 2 speed handicapping methods for horses with and without EIPH. Furosemide failed to prevent the development of EIPH in many horses that were previously considered to be EIPH-negative. When given furosemide, 62 (25.3%) of 235 EIPH-negative horses were EIPH-positive after racing. Furosemide had questionable efficacy for prevention of EIPH in known EIPH-positive horses. Thirty-two (61.5%) of 52 EIPH-positive horses given furosemide before a race remained EIPH-positive after that race. 相似文献
19.
Wilke M Nixon AJ Malark J Myhre G 《Journal of the American Veterinary Medical Association》2001,219(6):801-804
OBJECTIVE: To determine clinical and radiographic findings, treatment, and outcome of horses with fractures of the palmar aspect of the radial carpal bone, with or without concurrent fractures of the palmar surfaces of the other carpal bones. DESIGN: Retrospective study. ANIMALS: 10 horses. PROCEDURE: Medical records were reviewed to obtain information on history, signalment, clinical and radiographic findings, treatment, and outcome. Follow-up information was gathered from owners and referring veterinarians. RESULTS: 7 horses became lame after recovery from general anesthesia for treatment of an unrelated problem. The remaining 3 horses developed a fore-limb lameness after falling (1 horse) or being turned out in a pasture (2 horses). Fractures involved the palmar surface of the radial carpal bone in all 10 horses; in addition, the ulnar carpal bone was affected in 2 horses, the intermediate carpal bone in 2 horses, and the distal aspect of the radius in 4 horses. None of the 4 horses treated nonsurgically returned to work, and 3 were euthanatized because of recalcitrant lameness. In the other 6 horses, fragments were removed surgically. Two were euthanatized because of continued lameness, 1 was euthanatized for other reasons, 2 were sound enough for light work, and 1 returned to athletic work. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that fractures of the palmar aspect of the carpal bones are uncommon in horses. The prognosis appears to be poor for affected horses but may be better for horses that undergo arthroscopic removal of intra-articular fragments. 相似文献