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蛋鸡脂肪肝综合征的病因及其发病机理 总被引：4，自引：0，他引：4
蛋鸡脂肪肝综合症是一种营养代谢性疾病。它是由于鸡产蛋高峰期机体代谢旺盛 ,引起脂肪代谢紊乱 ,导致极低密度脂蛋白合成及转运受阻 ,使肝脏中合成的脂肪酸不能排出 ,造成甘油三酯在肝细胞内过度沉积。它导致青年蛋鸡不明原因的产蛋率下降和死亡率上升。本文对脂肪肝发病的症状、病因、发病机理进行综述 相似文献
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《畜牧兽医科技信息》2021,(10)
鸡蛋是我国人民常食的食品之一,因此蛋鸡的饲养也成为影响民生水平的重要产业。蛋鸡在养殖中会受到脂肪肝综合症的影响,出现蛋鸡产蛋率下降甚至死亡的问题,带来巨大经济损失。本文将介绍蛋鸡养殖存在的问题及脂肪肝综合症的危害与治疗,供参考。 相似文献
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对日粮多不饱和脂肪酸对蛋鸡体内脂肪代谢、血液中胆固醇和甘油三酯含量以及鸡蛋内胆固醇含量的影响进行了综述。机体脂肪代谢与日粮不饱和脂肪酸的种类和含量密切相关。日粮多不饱和脂肪酸参与体脂肪合成,影响体内极低密度脂蛋白和低密度脂蛋白的含量。机体血液中的甘油三酯和胆固醇含量随着日粮中多不饱和脂肪酸的种类和含量的变化而变化。鸡蛋中胆固醇的含量可以通过营养调控来减低,调节日粮中多不饱和脂肪酸的种类和含量可调控鸡蛋内胆固醇的含量。 相似文献
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产蛋鸡突然死亡的原因及预防青岛市畜牧兽医工作站栾翠香目前，仍有不少鸡场出现产蛋鸡突然死亡，从发病情况看，原因是由鸡出血性脂肪肝综合症引起。以肝脏沉积大量脂肪，引起脂肪变性为特性，这种病对蛋鸡饲养业危害很大。本病多发于高产蛋鸡群，特别是３５－６０周龄的... 相似文献
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脂肪肝综合症对蛋鸡产蛋性能、肝重、腹脂重及肝脏组织学变化的影响研究 总被引：2，自引：0，他引：2
蛋鸡脂肪肝综合症 (Fattyliversyndrome ,FLS)或脂肪肝出血性综合症 (FattyLiverHemorrhagicSyndrome ,FLHS)是产蛋鸡的一种常见病。其特征为病鸡肝肿大 ,多脂和易碎。本病常见于产蛋高峰期膘情好的蛋鸡 ,并引起蛋鸡突然死亡 ,造成很大的经济损失。该病病因较复杂 ,目前大多数研究认为 ,饲料因素是脂肪肝综合症的主要病因。本研究旨在通过不同饲料日粮诱发蛋鸡脂肪肝综合症 ,以探讨该病对蛋鸡产蛋性能、肝重、腹脂重及肝脏组织学变化的影响。1 材料与方法1 1 试验鸡选择、分组及管理 选择 1 4周龄体重 1 40 0～ 1 5 0 0g的艾维因蛋… 相似文献
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蛋鸡脂肪代谢及脂肪肝防治研究进展 总被引：3，自引：0，他引：3
蛋鸡脂肪肝综合症 (ＦＬＨＳ)是一种营养性的疾病。主要原因是产蛋高峰期机体代谢旺盛 ,引起脂肪代谢紊乱 ,导致极低密度脂蛋白 (ＶＬＤＬ)合成及转运受阻 ,使肝脏中合成的脂肪酸不能及时排出 ,甘油三酯在肝脏过度沉积。当蛋鸡出现脂肪肝时 ,肝脏合成卵黄前体物质及黄蛋白的能力下降 ,影响卵泡发育 ,影响产蛋性能下降 ,重则引起肝肿大 ,肝质地脆性增加 ,导致肝脏毛细血管出血 ,引起鸡群死亡。ＦＬＨＳ易发生于高产蛋鸡 ,产蛋率越高越易发生 ,造成的危害越大。迄今 ,国内外对蛋鸡脂肪肝的研究颇多 ,但缺乏克服ＦＬＨＳ发生的有效方法。1 家… 相似文献
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鸡蛋胆固醇的沉积机制 总被引：12，自引：0，他引：12
本文综述了鸡蛋胆固醇的沉积机制。蛋黄胆固醇主要来源于肝脏合成的蛋黄前体—极低密度脂蛋白(VLDL)和卵黄蛋白原(VTG) ,蛋黄胆固醇含量主要取决于VLDL进入卵母细胞的数量。载脂蛋白 -B、载脂蛋白 -Ⅱ(apo -B、apo -II)和卵母细胞原生质膜的受体在VLDL代谢中起着重要作用。通过降低胆固醇合成或替代蛋黄胆固醇来降低蛋黄胆固醇含量作用有限 ,并可能影响卵巢的正常功能和产蛋率等。可望通过调控apo -II和VTG的基因表达来降低蛋黄胆固醇含量。 相似文献
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A comparative study was made of biliary and liver lipid compositions during the growth and egg laying periods of the broiler bird. The liver lipids showed high concentrations of triacylglycerols at seven weeks old which increased when egg laying proceeded. At seven weeks old the lipids of the bile also showed high levels of triacylglycerols which decreased with the onset of egg laying but increased slightly as egg laying proceeded. At seven weeks old the fatty acid composition of the bile triacylglycerols differed from that of the liver which in turn was different from that of the liver at the onset of egg laying. In particular the bile triacylglycerols had lower levels of oleic but higher levels of arachidonic and docosahexaenoic acids. By the late egg laying period, the fatty acid compositions of the bile and liver triacylglycerols were similar. The unique bile lipid composition and its changes are discussed in relationship to the major features of liver lipid metabolism in the broiler bird and the mechanism of lipid deposition during egg laying. 相似文献
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Ten laying hens with low plasma cholesterol levels and no signs of fatty liver syndrome were examined at necropsy. Liver coloration and deposition of body fat were not abnormal in such hens. Eleven nonlaying hens had signs of fatty liver syndrome. They were out of production for 1 to 3 months and had elevate plasma cholesterol levels. At necropsy, such hens had yellow livers, heavy deposits of body fat, and several involuted egg yolks, which were dark yellow. Intimal plaques were observed by light microscopy in the abdominal aortas of hens with low plasma cholesterol levels; the plaques contained little or no lipid and were composed of three or four rows of modified smooth-muscle cells. Aortic intimal plaques of hens with high plasma cholesterol levels were composed of 16 to 18 rows of modified smooth-muscle cells when examined by light microscopy. The plaques contained intracellular and extracellular lipid, indicating aortic atherosclerosis. Electron-microscopic observations of the abdominal aortas of both groups of hens were similar to light-microscopic observations, except that lipid, including cholesterol clefts, was seen both intracellularly and extracellularly in the thickened tunica intima of hens with high plasma cholesterol values. Thus, the presence of aortic atherosclerosis was confirmed by electron microscopy. It is suggested that the endogenous hypercholesterolemia and cessation of egg production, characteristic of severe fatty liver syndrome, originated from the reabsorption of involuted egg yolks and that such reabsorption caused the development of aortic atherosclerosis and deposition of excess body fat. 相似文献
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家禽脂肪酸代谢及其在禽蛋中的沉积和营养调控 总被引：1，自引：0，他引：1
在肝脏中载脂蛋白作用下,内源合成或外源获取的脂肪酸以甘油三酯的形式同胆固醇及其他脂类组装形成极低密度脂蛋白(VLDL)。VLDL经血液循环到达卵巢,穿过卵母细胞外层屏障后,经卵母细胞受体介导的内吞作用进入卵母细胞发生沉积。而机体的营养状况或饲粮中营养成分的改变可通过影响脂肪酸的从头合成或VLDL结构直接或间接影响禽蛋中脂肪酸的最终沉积。本文阐述了家禽体内脂肪酸的来源、转运与沉积过程,并探讨了脂肪酸代谢及其在禽蛋中沉积的营养调控。 相似文献
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OVR介导大量的血浆蛋白被产蛋鸡吸收到生长的卵母细胞中,是卵黄前体进入卵母细胞的瓶颈。到目前为止发现它不仅与最丰富、最重要的卵黄前体极低密度脂蛋白(VLDL)、卵黄蛋白原(VTG)结合,还结合丛生蛋白、α2-巨球蛋白(α2-M)、受体相关蛋白(RAP)、乳铁蛋白、核黄素结合蛋白(ribBP)等,这些成分占蛋黄干物质的绝大部分。OVR发生突变的蛋鸡,不能繁殖,并且具有严重的高脂血症。它所内吞的VLDL的数量是蛋黄胆固醇含量的决定因素,因此期望通过调控OVR来控制蛋黄胆固醇的含量。 相似文献
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Influence of sumac (Rhus Coriaria L.) and ginger (Zingiber officinale) on egg yolk fatty acid,cholesterol and blood parameters in laying hens 
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下载免费PDF全文 The aim of the study was to evaluate the potential effect of different levels of sumac (Rhus coriaria L.) seed powder and ginger (Zingiber officinale) root powder on egg yolk fatty acid composition, blood/yolk cholesterol in laying hen. A total of 63 (ATAK‐S: Domestic Turkish Laying Hens) laying hens (average weight: 1470 g each hen, 25‐weeks of age) were assigned to seven treatment diets including sumac seed (S) and ginger root powder (G) at 0 g/kg (control), 10 g/kg (S1), 20 g/kg (S2), and 30 g/kg (S3); 10 g/kg (G1), 20 g/kg (G2), or 30 g/kg in rations respectively, for 8 weeks. After a two‐week adaptation period to cages, the hens were allocated to 7 groups with 9 replicates of 1 hen in per cage each. The replications were allotted equally into the upper and lower cages to minimize the effects of cage level. In this study, egg yolk cholesterol had a decrease (p <0.05) in supplemented diet( sumac seed and ginger root powder). Fatty acid content in yolk; saturated fatty acid, monounsaturated fatty acids, polyunsaturated fatty acids and rate of n6/n3 were not significant (p <0.05). However, dietary supplementation with sumac and ginger powder reduced and yolk/blood cholesterol concentrations in laying hens. Supplementation of sumac and ginger affected on HDL, there was found a significant effect (p < 0.05) in treatment groups. Moreover, LDL positively decreased in all treatment groups compared with the control group. The findings of this study suggested that feeding sumac and ginger tend to be decreasing cholesterol levels in both yolk and blood on laying hens. It can be concluded that ginger root and sumac seed powder can be used as an effective feed additive to improve fatty acid composition and yolk and blood cholesterol in ATAK‐S laying hens. 相似文献
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Liu WM Zhang J Lu LZ Shi FX Niu D Wang DL Yu B Tao ZR Shen JD Wang DQ Tian Y 《British poultry science》2011,52(3):381-387
1. The aim of this study was to identify the effect of perilla extract, a source of polyunsaturated fatty acids, on lipid metabolism and expression of lipid-related genes in livers of Shaoxing ducks. 2. Two hundred and forty 28-week-old laying ducks received a commercial diet with perilla extract added at 0 (control) or 200 mg/kg of feed. 3. Ducks fed on a diet with perilla extract had increased laying rates compared with control ducks. 4. Serum concentrations of triglycerides were reduced by perilla extract, while high-density lipoprotein cholesterol and total serum cholesterol increased. 5. The expression of genes involved in hepatic lipogenesis, sterol regulatory element-binding protein-1, acetyl CoA carboxylase, stearoyl CoA desaturase, fatty acid synthase, apolipoprotein B, and apolipoprotein very low density lipoprotein, were decreased in the perilla group. 6. The mRNA expression of peroxisome proliferators-activated receptor alpha and acyl-coenzyme A oxidase was enhanced following treatment with perilla extract, and a similar tendency was observed in the expression of liver fatty acid-binding protein. 7. The results show that a diet with 200 mg/kg perilla extract regulated fat metabolism of Shaoxing ducks by improving egg laying, altering serum lipid profiles, stimulating lipid catabolic gene expression and inhibiting lipogenic gene expression in the liver. 相似文献
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Effect of dietary Rhodobacter capsulatus on lipid fractions and egg-yolk fatty acid composition in laying hens 总被引：1，自引：0，他引：1
Salma U Miah AG Tsujii H Schellander K Südekum KH 《Journal of animal physiology and animal nutrition》2012,96(6):1091-1100
The present study was conducted to investigate the effect of dietary Rhodobacter capsulatus on lipid fractions and egg‐yolk fatty acid composition in laying hens. Thirty‐six laying hens (30 weeks old) were randomly assigned into two dietary groups fed diets with (0.04%) or without (control) R. capsulatus for a 60‐day feeding trial. Dietary R. capsulatus decreased (p < 0.05) serum and hepatic cholesterol and increased (p < 0.05) the excreta cholesterol, and resultant lower (p < 0.05) cholesterol contents in egg yolk. The concentration of polyunsaturated fatty acids (PUFA) and ratio to saturated fatty acids in egg yolk was improved (p < 0.05) by dietary R. capsulatus. The concentration of hepatic bile acid was increased (p < 0.05) and excreta bile acid was decreased (p < 0.01) in the laying hens fed R. capsulatus diet. The incorporation of 1‐14C‐palmitic acid into hepatic lipids and lipid fractions was increased (p < 0.05) in laying hens fed R. capsulatus diet. Moreover, dietary R. capsulatus did not appear to cause any adverse effects on laying hen performances. Therefore, dietary supplementation of R. capsulatus in layer diets may be a feasible means of producing eggs with lower cholesterol and higher PUFA contents for health conscious consumers. 相似文献