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1.
猪支原体肺炎(猪气喘病)是由猪肺炎支原体引起的一种严重危害全球养猪业生产的传染病之一。到目前为止,控制该病最有效的方法就是彻底的净化病原。制定一个合理的用药方案是净化成功与否的关键。本文就猪肺炎支原体敏感药物做一介绍,并列举了国外不同净化程序的不同给药方案,为国内猪气喘病净化提供依据。  相似文献   

2.
正猪支原体肺炎,又名猪气喘病,是全世界广泛存在的一种严重危害养猪业健康发展的主要猪病之一。我国是世界养猪大国,每年在猪气喘病上损失百亿元以上,目前在免疫缺陷性疾病中存在,特别是当前在蓝耳病广泛存在下,本病作为一个诱导其他疾病发生的重要因子,具有举足轻重的地位。控制和净化该病是世界养猪业面临的难题,疫苗免疫接种是控制猪气喘病的有效措施。目前国内有多家生产的猪支原体肺炎疫苗,其中猪支原体肺炎活疫苗(168株)等国内产品为活疫苗,其他进口  相似文献   

3.
猪支原体肺炎是由猪肺炎支原体引起的一种慢性接触性呼吸道传染病,又称猪地方性流行肺炎及猪气喘病等.猪支原体肺炎广泛分布于世界各地,是较难净化的猪病之一.该病可造成猪生长发育不良,导致继发感染,引发猪呼吸道综合征甚至死亡.其诊断如下. 1 材料和方法 1.1 试验动物 某养殖场35日龄左右三元杂交保育猪133头.病猪喘气、...  相似文献   

4.
《养猪》2016,(6)
正猪支原体肺炎是由猪肺炎支原体感染所引发的一种慢性接触性呼吸道疾病,又称猪地方流行性肺炎,该病一直被认为是对养猪业造成重大经济损失、最常发生、流行最广、最难净化的重要疫病之一。患病母猪通过接触能直接传染乳猪,被感染的乳猪在离乳后再感染其他的猪群,高密度的饲养能够促使本病的传播。由于猪支原体肺炎的潜伏期较长,因此很多猪群在不被发觉的情况下感染,致使本病在猪群中常年存在。该病在世界广泛流行,猪群感染率  相似文献   

5.
猪气喘病群防群治诊断   总被引:1,自引:0,他引:1  
猪气喘病又称地方流行性肺炎、支原体肺炎.是由猪肺炎支原体引起的猪的一种慢性、接触性传染病。该病多呈慢性经过,常见有其他病菌继发感染,该病也是规模化猪场常见的疾病之一,也是SPF猪场要求净化的疾病之一。其主要临床诊断症状为咳嗽和气喘。呼吸困难,肺有融合性支气管肺炎病变。  相似文献   

6.
猪支原体肺炎俗称猪气喘病,是目前乃至今后一段时间影响养猪业的重要疾病。该病的防治是控制猪场呼吸道综合征难题的关键。因此,有必要了解该病的病原特征、临床症状以及检测方法等,把有效预防和控制、净化支原体肺炎作为一项重要的工作。  相似文献   

7.
猪肺炎支原体是引起猪支原体肺炎的主要病原,严重危害着养猪业的发展。本文综合国内外猪肺炎支原体主要免疫原及疫苗的研究进展,从而为猪肺炎支原体致病机理的进一步研究及该病的防治提供新思路。  相似文献   

8.
随着我国农业的不断发展,目前生猪养殖已成为农户的第二收入来源。而猪支原体肺炎是养殖场较为常见的传染病,对生猪有较大的危害,当混合感染时疾病的诊治难度增加,给猪场和养殖户造成较大的经济损失。猪支原体肺炎又称猪地方性肺炎、猪喘气病,该病病原为猪肺炎支原体,是一种慢性、接触性呼吸道传染病,该病可引起猪只生长迟缓,料肉比上升、日增重减少等,延长了肥猪出栏时间。猪支原体肺炎可对猪造成严重免疫抑制。该病分布较广,是世界养猪业较为关注的重要疫病。  相似文献   

9.
猪支原体肺炎(Mycoplasmal pneumonia of Swine,MPS),是由猪肺炎支原体(Mycoplasma hyopneumoniae,Mhp)引起猪以咳嗽和气喘为主要症状的慢性接触性呼吸道传染病.各年龄段猪对该病均敏感,该病大多数是慢性经过,主要表现为咳嗽、呼吸困难,解剖可见肺组织病变或大理石病变.其主要危害是引起猪的生长受阻及饲料转化率大幅下降,患病猪长期生长发育不良,目前是全世界流行最广,最难净化,被认为是威胁全球养猪业的主要传染病之一.  相似文献   

10.
猪气喘病是集约化养猪场常见的疫病之一,也是SPF猪场要求净化的疫病.该病是由肺炎支原体引起的猪的一种慢性、接触性传染病.  相似文献   

11.
目的:通过对某猪场母猪实施猪瘟控制(净化)方案,研究分析能否提高该猪场的母猪分娩率。方法:采用酶联免疫吸附试验(ELISA)对龙岩市某规模化猪场的母猪进行猪瘟抗体检测,对猪瘟抗体检测不合格(阻断率小于40%)且同时满足两条及以上淘汰标准的种猪实行淘汰以达到猪瘟控制(净化)目的,并对猪瘟控制(净化)前后配种分娩结果进行收集、统计。结果:猪瘟控制(净化)后,母猪返情、流产、空胎数量减少,分娩率明显提升。结论:猪瘟控制(净化)可以提高母猪分娩率,实行猪瘟控制(净化)对规模化猪场具有重大意义。  相似文献   

12.
复方恩诺沙星注射液对人工诱发猪气喘病的治疗效果研究   总被引:2,自引:0,他引:2  
复方恩诺沙星注射液能有效控制猪气喘病感染,缓解症状,降低支原体感染猪的发病率和死亡率,并在一定程度上减少成活猪的体重下降,效果优于单方的恩诺沙星注射液和磺胺嘧啶钠注射液,在临床上有一定的实用价值。作者采用 0.04、0.08、0.12 mL/kg体重的2.5%复方恩诺沙星注射液分别对人工诱发猪气喘病进行肌肉注射治疗,结果表明,肌肉注射0.08 mL/kg体重复方恩诺沙星效果较好。  相似文献   

13.
Two herds of swine, believed to be free from mycoplasmal pneumonia of swine (MPS) based upon negative Mycoplasma hyopneumoniae microtiter complement fixation test (CFT) results, subsequently exhibited clinical signs of MPS.Lungworms (Metastrongylus spp.) were common to both herds. The possibility that lungworms could serve as a reservoir for M. hyopneumoniae was investigated. Lungworm-larvae-infected earthworms, collected from each of the farms, were fed to swine free of lungworms and MPS. This procedure resulted in lungworm infection in the recipient pigs, but failed to produce pneumonic lesions or CFT antibody titers against MPS.  相似文献   

14.
混合感染背景下的猪气喘病较难控制,介绍了猪气喘病的发病特点,常用药物的敏感度评价、疫苗效果评价和猪场猪气喘病的检查检测方法,结合作者实际经验强调了饲养管理要点,指出了种猪场净化猪气喘病的方法步骤,为混合感染下控制猪气喘病提供参考。  相似文献   

15.
Mycoplasma pneumonia of swine (MPS) is caused by Mycoplasma hyopneumoniae (M.hp) and is a common chronic respiratory disease of pigs. Recently, a genetically selected variant of the Landrace pig (Miyagino L2) has a lower incidence of pulmonary MPS lesions. We investigated the pathological and immunological characteristics of MPS resistance in these pigs (n = 24) by comparing with the normal landrace pig (control: n = 24). The pathological MPS lung lesion score in MPS‐selected landrace pigs was significantly lower than in the control. The gene expression of interleukin (IL)‐12p40, which acts as a chemoattractant and a component of the bioactive cytokines IL‐12 and IL‐23, was significantly higher at the hilar lymph nodes, lung, and spleen in MPS‐selected landrace pigs than in control landrace pigs, and these were negatively correlated with the macroscopic MPS lung lesion score. In summary, we demonstrate that resistance against MPS in Miyagino L2 pigs is associated with IL‐12p40 up‐regulation, in comparison with normal landrace pigs without the MPS vaccine. In addition, a comparative study of macroscopic MPS lung lesions and IL‐12p40 gene expression in lung and hilar lymph nodes may lead to beneficial selection traits for the genetic selection for MPS resistance in pigs.  相似文献   

16.
Five generations of Landrace pigs selected for average daily gain, backfat thickness, Mycoplasmal pneumonia of swine (MPS) lesion score, and plasma cortisol levels, was executed to decrease the MPS lesion score. Genetic parameters and correlated genetic responses for respiratory disease and peripheral blood immune traits were estimated in 1395 Landrace pigs. We estimated the negative genetic correlation of MPS lesion score with phagocytic activity (PA) at 7 weeks of age (‐0.67). The breeding values of PA at 7 weeks of age and 105 kg body weight and the correlated selection response of the ratio of granular leukocytes to lymphocytes at 105 kg body weight were significantly increased, and sheep red blood cell‐specific antibody production (AP) was significantly decreased in a selection‐dependent manner. Increasing of natural immunological indicators (e.g. PA) and decreasing of humoral immunological indicator (e.g. AP) were observed due to genetically decreasing MPS lesion score.  相似文献   

17.
猪支原体肺炎流行病学和诊断技术研究进展   总被引:5,自引:1,他引:4  
论文概述了猪支原体肺炎的病原学特性、流行病学和诊断方法的研究进展,并对猪支原体肺炎临床检测、血清学检测、分子生物学检测等检测技术的优缺点进行比较.在猪支原体肺炎预防控制方面,对上述检测技术和诊断方法的应用进行了讨论和展望,旨在为研究该病提供理论参考.  相似文献   

18.
牛病毒性腹泻病毒侵染细胞机制的研究进展   总被引:2,自引:0,他引:2  
牛病毒性腹泻病毒(BVDV)是反刍动物和猪体内广泛存在的危害动物健康的重要病原体.BVDV感染牛后主要引起牛的持续性感染、免疫耐受、免疫抑制、繁殖障碍及急慢性黏膜病等临床症状,给养牛业造成重大的损失.其致病机理非常复杂,给该病的治疗和根除带来极大的困难.随着分子病毒学研究的发展以及对猪瘟病毒和黄病毒科其他成员的研究,人们在BVDV分子水平和细胞水平的研究方面也取得了一些进展.就此,作者从BVDV入侵细胞、在细胞内的复制以及与宿主蛋白分子相互作用等方面进行综述,有助于阐明BVDV致病和在体内持续存活的机制,为该病的防治和疫苗研发提供新的思路和对策.  相似文献   

19.
Mycoplasma pneumonia of swine (MPS) is responsible for significant economic losses in the swine industry. We selected Landrace pigs for reduced MPS pulmonary lesions over five generations, and measured concentrations of the following cytokines: interleukin (IL)‐10, IL‐13, IL‐17, tumor necrosis factor (TNF)‐α and interferon (IFN)‐γ to estimate their correlation with MPS lesions. Sheep red blood cells (SRBC) were injected twice intramuscularly at 70 and 95 kg body weight. Blood serum samples were collected after 1 week of secondary SRBC inoculation and cytokine concentrations were analyzed by ELISA. Genetic parameters and breeding values were estimated. The heritability estimates of IL‐10, IL‐13, IL‐17, TNF‐α and IFN‐γ were 0.20 ± 0.06, 0.12 ± 0.06, 0.27 ± 0.07, 0.20 ± 0.10 and 0.05 ± 0.03, respectively. Genetic correlations of IL‐17 and TNF‐α with pulmonary MPS lesions were high (‐0.86 ± 0.13 and 0.69 ± 0.29, respectively) and those of IFN‐γ and IL‐13 with MPS lesions were moderately negative (‐0.45). Through selection, the breeding values of IL‐17 and IFN‐γ increased substantially and those of TNF‐α decreased. These results suggest that innate and cellular immunity are more important for the suppression of pulmonary lesions in MPS than humoral‐mediated immunity, such as antibody response.  相似文献   

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