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101.
Galina P. Simeonova Svetozar Z. Krastev Radostin S. Simeonov 《Veterinary research communications》2016,40(3-4):107-115
Background
The pathogenic mechanism of equine recurrent uveitis (ERU) is still poorly defined and many variations between experimental animal models and spontaneous disease exist.Objectives
The aim of our study was to investigate if Th17 cell-mediated response plays role in the pathogenesis of the used experimental model in horses and to reveal its pathological findings.Methods
Experimental uveitis was induced in 6 healthy horses. The concentrations of retinal autoantigen CRALBP and IL-17 were measured using ELISA in aqueous humor and vitreous body of the 12 inflamed eyes as well as in 12 control non-inflamed eyes taken from 6 horses in slaughter house. After centrifugation of the two eye media, smears were prepared and cytological investigation was performed. Tissue specimens were taken from all eye globes and were submitted to histopathological investigation.Results
CRALBP and IL-17 concentrations were significantly elevated in eye media of horses with experimental uveitis in comparison with controls. Cytological and histopathological findings corresponded to the changes characteristic of chronic immune-mediated inflammation with mononuclear cell infiltration of uvea, choroid, retina, and eye media as well as severe retinal destruction.Conclusions
Our study demonstrated the involvement of the retinal autoantigen CRALBP as well as IL-17 in the pathogenesis of experimental uveitis in horses. These findings suggests that this experimental uveitis in horses may serve as a suitable animal model for investigation of IL-17- mediated immune response during spontaneous autoimmune uveitis in horses as well as in humans.102.
Symmetrical alopecia, scaling and hepatitis in a rabbit 总被引：2，自引：1，他引：1
A 5-year-old rabbit with inappetence, symmetrical alopecia and skin lesions was examined. No mites or Malassezia were found in skin scrapings and tape impressions and dermatophyte culture was negative. Trial therapy with ivermectin did not reduce skin lesion severity, and euthanasia was performed because of anorexia after 1 month. Histopathology of the skin showed hyperkeratosis, lymphocytic exocytosis, cell-poor interface dermatitis (lymphocytic infiltration and apoptotic cells in basal layer of epidermis), absence of sebaceous glands and lymphocytic mural folliculitis comparable to sebaceous adenitis and thymoma-associated exfoliative dermatitis previously described in rabbits. The liver exhibited an interface hepatitis, comparable to autoimmune hepatitis in man. The occurrence of morphological similarities to exfoliative dermatitis and sebaceous adenitis in rabbits, in association with an autoimmune hepatitis, has not been described before. 相似文献
103.
Changyao Shan Baishu Li Li Li Xin Du Yonglin Ren Simon J. McKirdy Tao Liu 《Pest management science》2023,79(12):4942-4951
104.
丁元翠方素庭徐廉竹张锋燕胡倩倩李升和任曼 《动物营养学报》2023,(4):2336-2348
本试验旨在研究苏氨酸和异亮氨酸对皖西白鹅屠宰性能、器官指数及肠道形态结构、消化酶活性、抗氧化和免疫指标的影响。选取30日龄体重相近的皖西白鹅180只,随机分为3组,每组3个重复,每个重复20只。对照组饲喂基础饲粮,苏氨酸组在基础饲粮中添加2.0 g/kg的L-苏氨酸,异亮氨酸组在基础饲粮中添加2.5 g/kg的L-异亮氨酸。试验期60 d。结果表明：1）各组之间90日龄屠宰性能和器官指数无显著差异（P>0.05）。2）异亮氨酸组60日龄十二指肠和空肠绒毛高度、隐窝深度显著或极显著高于对照组（P<0.05或P<0.01）,苏氨酸组60日龄十二指肠、空肠和回肠隐窝深度及90日龄十二指肠和回肠绒毛高度显著或极显著高于对照组（P<0.05或P<0.01）。3）苏氨酸组和异亮氨酸组60、90日龄十二指肠胰蛋白酶活性极显著高于对照组（P<0.01）,苏氨酸组60、90日龄十二指肠麦芽糖酶活性及90日龄空肠淀粉酶、乳糖酶活性显著或极显著高于对照组（P<0.05或P<0.01）。4）异亮氨酸组60日龄空肠总抗氧化能力显著高于对照组和苏氨酸组（P<0... 相似文献
105.
小麦红吸浆虫在土内有4种虫态,其分布以中层(7～13厘米)最多,下层(13～20厘米)次之,上层(0～7厘米)最少,20～38厘米仍有虫口分布.幼虫以上层为最多,中层次之、下层最少;圆茧以中,下层最多,上层很少;长茧及蛹以上层为最多,中、下层较少.成虫发生迟早及持续时间长短的关键因素是3～5月的降雨量,其中以4月下旬降雨最为重要.4月下旬降雨多,则成虫发生早,持续时间长,成虫发生盛期与小麦抽穗期相吻合的机会多,小麦受害重.在小麦抽穗前施一次长效农药封闭地面,可杀死不断上升地面的幼虫和蛹,阻止成虫羽化. 相似文献
106.
Ran Li Ren Zhen Huang Wenying 《保鲜与加工》1993,(6):21-26
A new Monte Carlo Method for system reliability evaluation is proposed in this paper. The repeated sampling of system states with relatively great probabilities is avoided in the simulation,thus the sampling efficiency is significantly improved. Besides,the negative correlations used in different trials can further reduce the estimated varinaces. The sparse matrix technique is employed to reduce the memory requirement and to save the computer time. Comparative studies show that the method proposed is of great value and the application to the IEEE reliability test system (power system) is successful. 相似文献
107.
Zhang Wei Ren Zhen Qin Yihong Liao Qing 《保鲜与加工》1990,(1):56-62
A flexible mathematical model used for dynamic simulation studies of HVDC systems which is based on the stale variable method is presented, and the correspongding computer program has been implemented. Generality, easy to use, and suitable to run on microcomputers are the main features of the model and the computer program. Therefore the model is easy to be extended for application. An example is given in the paper to verily the coneclness of the model and the program. 相似文献
108.
109.
Ren Yuanzhi 《保鲜与加工》1994,(1)
The condition when forces are applied to load mechnical mornent limiter of tow-er cranes is analysed and disctissed in this paper.A lifting performance curve adapted for the me-chanical load moment limiter is also obtained.And finally,the curve drawing method is explainedthrough the practical example. 相似文献
110.