Salmon poisoning disease in two Malayan sun bears     

Gai JJ  Marks SL 《Journal of the American Veterinary Medical Association》2008,232(4):586-588

CASE DESCRIPTION: 2 captive sun bears (Helarctos malayanus) were evaluated because of acute onset of vomiting, mucoid diarrhea, lethargy, and anorexia 1 week after eating live trout from a northern California reservoir. CLINICAL FINDINGS: In 1 of the bears, a CBC and serum biochemical analyses revealed mild anemia, mild eosinophilia, moderate lymphopenia, moderate hypoalbuminemia, and high serum G-glutamyltransferase activity. Ultrasonographic examination of the same bear revealed ascites and mesenteric lymphadenopathy. Histologic examination of gastrointestinal tract biopsy specimens revealed moderate to severe lymphoplasmacytic and eosinophilic gastritis, enteritis, and colitis. Ova of Nanophyetus salmincola, the trematode vector of Neorickettsia helminthoeca (a rickettsial organism that causes salmon poisoning disease), were detected in fecal samples from both bears. TREATMENT AND OUTCOME: The bears were treated with oxytetracycline, doxycycline, praziquantel, and famotidine. Within 1 week after initiation of treatment, the appetite and fecal consistency of each bear were considered normal. Fecal ova shedding began 4 days after onset of clinical signs and ceased 9 days later. CLINICAL RELEVANCE: Salmon poisoning disease can be rapidly fatal in untreated animals, but if diagnosed early and treated appropriately, full recovery can be achieved. Domestic dogs and captive exotic bears are highly susceptible to clinical disease after ingestion of trematode-infected fish. Salmon poisoning disease may develop outside the geographic range in which the causative organism is endemic as a result of the transplantation of infected fish for sport fishing; veterinarians practicing in areas where infected fish may be transplanted should be aware of appropriate diagnostic and treatment protocols.  相似文献   

Prevalence,radiographic resolution and outcomes of slab fractures of the third and central tarsal bones in juvenile Thoroughbred horses     

CM Steel  VL Collins  SR Hance  AR Adkins  PL Hitchens 《Australian veterinary journal》2019,97(4):108-115

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Micromechanical "Trampoline" magnetometers for use in large pulsed magnetic fields     

V Aksyuk  FF Balakirev  GS Boebinger  PL Gammel  RC Haddon  DJ Bishop 《Science (New York, N.Y.)》1998,280(5364):720-722

A silicon micromechanical magnetometer was constructed and successfully used in 60-tesla pulsed magnetic fields of less than 100-millisecond duration. The device is small, inexpensive to fabricate, and easy to use. It features a fast mechanical response (up to 50,000 hertz) and extremely high sensitivity yet is relatively robust against electrical and mechanical noise. Quantum oscillations in the magnetization of a 1-microgram sample of an organic superconductor, kappa-[bis(ethylenedithio)tetrathiafulvalene]2Cu(NCS)2, have been observed with this device.  相似文献   

Effects of glutamine supplementation of an amino acid-based purified diet on intestinal mucosal integrity in cats with methotrexate-induced enteritis.     

S L Marks  A K Cook  R Reader  P H Kass  A P Théon  C Greve  Q R Rogers 《American journal of veterinary research》1999,60(6):755-763

OBJECTIVE: To determine effects of glutamine-supplemented and glutamine-free amino acid-based purified diets, compared with a dry expanded diet, on intestinal structure and function in a model that used cats with methotrexate-induced enteritis. ANIMALS: 18 adult specific-pathogen-free cats. PROCEDURE: 12 cats were given intragastric feedings of an amino acid-based purified diet supplemented with glutamine (7% [wt:wt]) or an isonitrogenous amount of glycine and alanine; 6 cats consumed a dry expanded diet. After 21 days, cats received methotrexate (MTX; 11 mg/kg of body weight, IV). Intestinal permeability testing was performed immediately before and 66 hours after MTX administration. Celiotomy was performed 72 hours after MTX administration for aseptic removal of mesenteric lymph nodes, collection of full-thickness intestinal biopsy specimens, determination of intestinal cellular proliferation, and collection of aortic and portal venous blood samples for determination of arteriovenous amino acid concentrations across the intestine. RESULTS: Administration of MTX was associated with severe enterotoxicosis manifested as diarrhea (8/12 cats), vomiting (12/12), and positive results for bacterial culture of mesenteric lymph nodes (12/12) in cats receiving the purified diets, independent of glutamine supplementation. Diet did not affect villus tip length and villus surface area in the small intestine or cellular proliferation. Administration of MTX was associated with significantly increased intestinal permeability, which was not attenuated by glutamine supplementation. CONCLUSIONS: Feeding of a glutamine-supplemented amino acid-based purified diet was unable to preserve intestinal function in cats with MTX-induced enteritis. CLINICAL RELEVANCE: Intestinal morphologic alterations correlate poorly with intestinal function as measured by means of bacterial translocation and intestinal permeability.  相似文献   

Sensory Descriptive Texture Analyses of Cooked Rice and Its Correlation to Instrumental Parameters Using an Extrusion Cell     

Jean-Francois C. Meullenet  Jason Gross  Bradley P. Marks  Melissa Daniels 《Cereal Chemistry》1998,75(5):714-720

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Equine amnionitis and fetal loss: The case definition for an unrecognised cause of abortion in mares     

KH Todhunter  NR Perkins  RM Wylie  C Chicken  AJ Blishen  DJ Racklyeft  G Muscatello  MC Wilson  PL Adams  JR Gilkerson  WL Bryden  AP Begg 《Australian veterinary journal》2009,87(1-2):35-38

A series of abortions occurred in mares in New South Wales during 2004 that involved similar and unusual findings on post mortem examination of aborted fetuses and fetal membranes. The term Equine Amnionitis and Fetal Loss (EAFL) was developed to describe the condition. This form of abortion had not been previously recognised in Australia. The pathology alone is not specific for EAFL and diagnosis requires demonstration of a combination of certain pathological and bacteriological features. The purpose of this paper is to describe patterns considered consistent with EAFL cases as a working case definition for use by veterinarians and veterinary pathologists in identifying future cases of EAFL. More detailed papers are in preparation to fully describe the epidemiological, histopathological, and microbiological aspects of EAFL.  相似文献   

Parenteral nutrition in neonatal foals: clinical description, complications and outcome in 53 foals (1995-2005)     

Myers CJ  Magdesian KG  Kass PH  Madigan JE  Rhodes DM  Marks SL 《Veterinary journal (London, England : 1997)》2009,181(2):137-144

This retrospective study describes the use of and complications associated with parenteral nutrition (PN) administration to 53 equine neonates at the University of California Veterinary Medical Teaching Hospital. Medical records were examined and information obtained on signalment, physical examination, clinical diagnosis, outcome, total hospitalization time, insulin administration, microbiology culture results, other complications (i.e. thrombophlebitis) and necropsy findings. Complete blood count and serum biochemistry analytes, venous blood gas, serum electrolyte and glucose concentrations, and blood lactate concentration results were compared before and during PN administration in all foals. Seventeen foals (32%) developed hypertriglyceridemia (>200mg/dL). Triglyceride concentrations >200mg/dL were significantly (P=0.049) associated with non-survival. Forty-seven foals (89%) developed hyperglycemia (blood glucose >120mg/dL) and eight (15%) developed catheter-related complications (thrombosis or local sepsis). Packed cell volume, total protein, creatinine, blood urea nitrogen, and sorbitol dehydrogenase concentrations decreased while foals were on PN, while serum chloride concentration increased. This study highlighted that hypertriglyceridemia during the acute phase of neonatal illness may be detrimental to outcome, and that the safety of lipid-containing solutions in foals warrants further study.  相似文献   

Anesthetic effects of different volumes of lidocaine for spermatic cord block in cattle     

Ana C. Neves  Juracy CB. Santos Júnior  Rodrigo L. Marucio  Monica Midon  Stelio PL. Luna 《Veterinary anaesthesia and analgesia》2017,44(2):375-378

Objective

To evaluate three volumes of lidocaine for spermatic cord block to perform castration in cattle.

Study design

Randomized blinded clinical study.

Animals

Thirty mixed-breed Nellore cattle, aged 28–40 months and weighing 395 ± 21 (352–452) kg [mean ± standard deviation (range)].

Methods

Cattle were restrained in a chute and allowed to stand without sedation. Three milliliters of 2% lidocaine without epinephrine were infiltrated subcutaneously at each site of scrotal incision in all animals. The animals were allocated to three groups of 10 animals each. Lidocaine 2% was injected into each spermatic cord using a volume of 2, 3 or 4 mL in groups A, B, or C, respectively. The total volumes of lidocaine used were 10, 12, and 14 mL in groups A, B, and C, respectively. The duration of surgery and the retraction of the testicle (scored as positive or negative according to retraction of the testicle) during the procedure were recorded. The data were statistically analyzed by one-way anova followed by Tukey’s and chi-square tests. Differences were considered significant when p < 0.05.

Results

The mean surgical time was shorter in group C than in groups A and B (p < 0.001). In groups A, B and C, 90%, 60% and 10% of the animals showed retraction of the testicle, respectively. Fewer animals retracted the spermatic cord in group C than in group A (p = 0.002) and B (p = 0.02).

Conclusions and clinical relevance

Optimal spermatic cord block was achieved by injection of 4 mL of 2% lidocaine 5 minutes before castration and following incisional infiltration of lidocaine, in adult cattle weighing about 400 kg.  相似文献   

What is your diagnosis? Plasma cell neoplasia     

Marks AL  Gaschen L  Tully TN  Grasperge BJ  Rich GA 《Journal of the American Veterinary Medical Association》2010,237(9):1033-1034

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Postoperative analgesic effects of intravenous,intramuscular, subcutaneous or oral transmucosal buprenorphine administered to cats undergoing ovariohysterectomy     

Tatiana Giordano  Paulo VM Steagall  Tatiana H Ferreira  Bruno W Minto  Sílvia Elaine Rodolfo De Sá Lorena  Juliana Brondani  Stelio PL Luna 《Veterinary anaesthesia and analgesia》2010,37(4):357-366

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