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排序方式: 共有273条查询结果,搜索用时 15 毫秒
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Alexandra Dixon Annie Chen John H. Rossmeisl Beverly Sturges Karen Vernau Jonathan M. Levine Arturo Otamendi Peter Early Alix Partnow Lara Curtis Stephanie Thomovsky Rebecca A. Packer Daniela A. Mauler 《Veterinary and comparative oncology》2019,17(4):472-478
Vertebral osteosarcoma (OSA) is the most common primary vertebral tumor in dogs, however studies examining the survival time after surgical decompression of these tumors are limited. There is also limited information regarding the benefit of adjunctive treatments such as radiation therapy or chemotherapy in these patients. The goal of this study was to determine survival time of dogs with primary vertebral OSA after palliative decompressive surgery alone and combined with radiation therapy and/or chemotherapy. Records from 22 client‐owned dogs diagnosed with primary vertebral OSA and treated with decompressive surgery were collected retrospectively from eight referral institutions. Survival time was assessed for dogs treated with surgery alone as well as dogs who received adjunctive radiation therapy and/or chemotherapy. Median survival time in the 12 dogs treated with surgery alone was 42 days (range: 3‐1333 days). The three dogs treated with surgery and chemotherapy had a median survival time of 82 days (range: 56‐305 days). Only one dog was treated with surgery and radiation therapy; this dog survived 101 days. Six dogs were treated with surgery, radiation therapy and chemotherapy; these dogs had a median survival time of 261 days (range: 223‐653 days). Cause of death in all cases that survived the initial postoperative period was euthanasia secondary to confirmed or suspected tumor regrowth. The results of this study suggest that definitive radiation therapy, possibly combined with concurrent chemotherapy, significantly improves survival in dogs treated with palliative decompressive surgery for vertebral OSA and should be the treatment of choice in selected cases. 相似文献
33.
Pollen donors of acorns and saplings in a stand of bur oak were identified by paternity exclusion using microsatellite genotype analysis. Here we examine the influence of several factors likely to affect reproductive success of males with wind-dispersed pollen, including distance of pollen donor from maternal tree, genetic relatedness of pollen donor to maternal tree, direction of pollen donor relative to maternal tree, and size of pollen donor (crown volume and trunk diameter). Surprisingly, none of these factors were strongly correlated with fertilization success, although weak but significant correlations with crown volume and distance were found. The slight influence of distance is actually overestimated here, because our analysis necessarily excluded a large proportion of pollinations that were effected by trees outside the stand. The pollen donors outside the stand were not identified, but were more than 150 meters away. Pollination patterns in this stand of bur oak are quite complicated. Seed parents were fertilized by multiple pollen donors within the stand from all directions and as far as 200 m away. These results caution against the use of models of pollination that are based on simple distance or directional parameters because they will not adequately predict gene flow or male reproductive success. Our results further emphasize the importance of genetically identifying successful pollen donors rather than relying on patterns of physical movement of pollen. 相似文献
34.
Two depth profiles of the osmium concentration and the 187Os/186Os isotopic ratio in the Indian Ocean showed that the osmium concentration seems to be unaltered by chemical or biological processes occuring in seawater; accordingly, osmium is conservative. These data were obtained from an experimental method that eliminated the problems related to osmium preconcentration. This method led to a new evaluation of the concentration of osmium in seawater; the mean concentration of osmium and the 187Os/186Os ratio are equal to 10.86 +/- 0.07 picograms per kilogram and 8.80 +/- 0.07, respectively. The results suggest the existence of an organocomplex that dominates the speciation of osmium in seawater. 相似文献
35.
Unconditional quantum teleportation 总被引:5,自引:0,他引:5
A Furusawa JL Sorensen SL Braunstein CA Fuchs HJ Kimble ES Polzik 《Science (New York, N.Y.)》1998,282(5389):706-709
Quantum teleportation of optical coherent states was demonstrated experimentally using squeezed-state entanglement. The quantum nature of the achieved teleportation was verified by the experimentally determined fidelity Fexp = 0.58 +/- 0.02, which describes the match between input and output states. A fidelity greater than 0.5 is not possible for coherent states without the use of entanglement. This is the first realization of unconditional quantum teleportation where every state entering the device is actually teleported. 相似文献
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RL Westemeier JD Brawn SA Simpson TL Esker RW Jansen JW Walk EL Kershner JL Bouzat KN Paige 《Science (New York, N.Y.)》1998,282(5394):1695-1698
Effects of small population size and reduced genetic variation on the viability of wild animal populations remain controversial. During a 35-year study of a remnant population of greater prairie chickens, population size decreased from 2000 individuals in 1962 to fewer than 50 by 1994. Concurrently, both fitness, as measured by fertility and hatching rates of eggs, and genetic diversity declined significantly. Conservation measures initiated in 1992 with translocations of birds from large, genetically diverse populations restored egg viability. Thus, sufficient genetic resources appear to be critical for maintaining populations of greater prairie chickens. 相似文献
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Nik G. Wiman Daniel T. Dalton Gianfranco Anfora Antonio Biondi Joanna C. Chiu Kent M. Daane Beverly Gerdeman Angela Gottardello Kelly A. Hamby Rufus Isaacs Alberto Grassi Claudio Ioriatti Jana C. Lee Betsey Miller M. Valerio Rossi Stacconi Peter W. Shearer Lynell Tanigoshi Xingeng Wang Vaughn M. Walton 《Journal of pest science》2016,89(3):653-665
40.
B Serrano F López-Gatius P Santolaria S Almería I García-Ispierto G Bech-Sabat J Sulon NM de Sousa JF Beckers JL Yániz 《Reproduction in domestic animals》2009,44(4):600-605
This study was designed to establish the factors, if any, which could affect plasma pregnancy-associated glycoprotein-1 (PAG-1) expression in a study population of 87 pregnant, high-producing dairy cows. The factors examined were: semen providing breed (Holstein-Friesian vs Limousin), outcome of gestation (male vs female newborn, and singleton vs twin pregnancies), lactation number, milk production at pregnancy diagnosis, plasma progesterone concentration, season of gestation (warm period, March–November vs cool period, December–February), and day of gestation (40, 90, 120, 150, 180 and 210). Pregnancy was diagnosed by transrectal ultrasound on day 40 post-insemination and by palpation per rectum on days 90, 120, 150, 180 and 210. Blood samples were collected from each animal immediately before each pregnancy diagnosis. The relative contributions of the different factors on PAG-1 concentrations were evaluated by GLM repeated measures analysis of variance. No significant effects of the herd, foetal sex, milk production, lactation number and plasma progesterone concentrations were observed. In contrast, twin pregnancy, the use of Limousin semen and conception during the cool period were correlated with significantly increased plasma PAG-1 concentrations throughout gestation. Our data indicate that both cow well-being during early placental development, determined in our conditions by reduced heat stress when conception occurred in the cool season, and crossbreed pregnancies lead to improved PAG-1 production throughout the gestation period. 相似文献