Pericardial lipoma in a geriatric dog with an incidentally discovered thoracic mass     

Ben-Amotz R  Ellison GW  Thompson MS  Sheppard BJ  Estrada AH  Levy JK 《The Journal of small animal practice》2007,48(10):596-599

An intrathoracic mass was discovered as an incidental finding in a 14-year-old, spayed, female Rottweiler cross during evaluation of urinary incontinence. Computed tomography suggested a pericardial or pleural location and high adipose content of the mass. The mass was removed via lateral thoracotomy with partial pericardectomy and was diagnosed as a pericardial lipoma. The dog recovered well, and there was no evidence of recurrence approximately one year later. Adipose tumours of the heart and its associated structures are rare in dogs and have been associated with both successful and fatal outcomes.  相似文献   

Clinical, humoral and IFNgamma responses of cattle to infection with Mycoplasma mycoides var. mycoides small colony and attempts to condition the pathogenesis of the infection     

Scacchia M  Sacchini F  Filipponi G  Luciani M  Lelli R  Tjipura-Zaire G  Di Provvido A  Shiningwane A  Ndiipanda F  Pini A  Caporale V  Hübschle OJ 《The Onderstepoort journal of veterinary research》2007,74(3):251-263

Contagious bovine pleuropneumonia (CBPP), caused by Mycoplasma mycoides var. mycoides small colony (MmmSC), is one of the most important diseases of cattle in Africa. The role of innate or acquired cell mediated and humoral immunity in conferring protection against MmmSC infection has not yet been elucidated. On the other hand, the pathological lesions caused by the aetiological agent have been considered indicative of an immunopathological process. In this study ten na?ve cattle were exposed to in-contact infection with animals infected by intubation with a strain of MmmSC. Clinical signs, antibody response, IFNgamma release and pathological changes at necropsy were analysed and compared with the events following in-contact infection of an equal number of animals kept under daily treatment with cyclosporine for the entire observation period of 84 days. Cyclosporine is a suppressor of the immune response related to the T-cell system. Under the conditions of the experiment, cyclosporine appeared to condition the pathogenesis of CBPP by delaying the events that follow infection, bringing further support to the possibility that the immune response may have an impact on the disease outcome.  相似文献   

A descriptive epidemiological study on canine babesiosis in the Lake Geneva region     

Porchet MJ  Sager H  Muggli L  Oppliger A  Müller N  Frey C  Gottstein B 《Schweizer Archiv für Tierheilkunde》2007,149(10):457-465

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Correlation between cytopathology and histopathology of the skin, lymph node and spleen in 500 dogs and cats     

Ovejero Braun A  Hauser B 《Schweizer Archiv für Tierheilkunde》2007,149(6):249-257

The results of 382 cytological examinations in dogs and 118 in cats were retrospectively compared with the correlating histological results.The histological diagnosis represented the gold standard. The investigation comprised skin, lymph node and spleen samples. The aim was to estimate the diagnostic value and the limits of cytological examinations in relation to the type of the changes. The cases were grouped in six categories: Corresponding diagnoses were formulated in 201 cases. In lymph node samples, they were reached almost twice as frequently than in skin and spleen samples. Round cell neoplasias (mast cell tumours, canine cutaneous histiocytomas and malignant lymphomas) were most often subclassified. Cytological diagnoses lacking subclassification were reached in 98 cases. The lesions were cytologically less precisely characterized than histologically. Provisional cytological diagnosis or differential diagnosis were formulated in 112 cases. Most commonly, the distinction between neoplastic and non-neoplastic character of a lesion was not possible (especially in mesenchymal spindle-cell proliferations). In 53 cases, the cytological diagnosis could not be established. In 22 cases, the relevant lesion was diagnosed only histologically whereas the cytological picture revealed another, usually secondary tissue reaction. Cytologically incorrect diagnoses were formulated in 14 cases.  相似文献   

Molecular characterization of stem gall disease caused by Agrobacterium tumefaciens (= Agrobacterium biovar 1) on Citrus trees as a new host,in the Eastern Mediterranean region of Turkey     

Bozkurt  İ. Adem  Soylu  Soner  Kara  Merve  Doksöz  Senem Filiz  Altan  Bülent  Çarpar  Hakan 《植物病害和植物保护杂志》2023,130(1):13-21

Journal of Plant Diseases and Protection - Citrus (Citrus spp. L.), which has high nutritional and economic value, is one of the most commonly grown fruits in Turkey. In spring 2020, large aerial...  相似文献   

Extracellular heat shock protein 70 levels in tumour-bearing dogs and cats treated with radiation therapy and hyperthermia     

K. J. Nytko  M. S. Weyland  S. Dressel-Böhm  S. Scheidegger  L. Salvermoser  C. Werner  S. Stangl  A. C. Carpinteiro  B. Alkotub  G. Multhoff  S. Bodis  C. Rohrer Bley 《Veterinary and comparative oncology》2023,21(4):605-615

Hyperthermia is a form of a cancer treatment which is frequently applied in combination with radiotherapy (RT) to improve therapy responses and radiosensitivity. The mode of action of hyperthermia is multifactorial; the one hand by altering the amount of the blood circulation in the treated tissue, on the other hand by modulating molecular pathways involved in cell survival processes and immunogenic interactions. One of the most dominant proteins induced by hyperthermia is the major stress-inducible heat shock protein 70 (Hsp70). Hsp70 can be found in the blood either as a free-protein (free HSP70) derived from necrotic cells, or lipid-bound (liposomal Hsp70) when it is actively released in extracellular vesicles (EVs) by living cells. The aim of the study was to evaluate the levels of free and liposomal Hsp70 before and after treatment with RT alone or hyperthermia combined with radiotherapy (HTRT) in dogs and cats to evaluate therapy responses. Peripheral blood was collected from feline and canine patients before and at 2, 4, 6 and 24 h after treatment with RT or HTRT. Hsp70 enzyme-linked immunosorbent assays (ELISAs) were performed to determine the free and liposomal Hsp70 concentrations in the serum. The levels were analysed after the first fraction of radiation to study immediate effects and after all applied fractions to study cumulative effects. The levels of free and liposomal Hsp70 levels in the circulation were not affected by the first singular treatment and cumulative effects of RT in cats however, after finalizing all treatment cycles with HTRT free and liposomal Hsp70 levels significantly increased. In dogs, HTRT, but not treatment with RT alone, significantly affected liposomal Hsp70 levels during the first fraction. Free Hsp70 levels were significantly increased after RT, but not HTRT, during the first fraction in dogs. In dogs, on the other hand, RT alone resulted in a significant increase in liposomal Hsp70, but HTRT did not significantly affect the liposomal Hsp70 when cumulative effects were analysed. Free Hsp70 was significantly induced in dogs after both, RT and HTRT when cumulative effects were analysed. RT and HTRT treatments differentially affect the levels of free and liposomal Hsp70 in dogs and cats. Both forms of Hsp70 could potentially be further investigated as potential liquid biopsy markers to study responses to RT and HTRT treatment in companion animals.  相似文献   

Retrospective evaluation of indications,transfusion protocols,and acute transfusion reactions associated with the administration of lyophilized canine albumin: 53 cases (2009–2020)     

Emilia Terradas Crespo LV  MS  DACVECC  Linda G. Martin DVM  MS  DACVECC  Elizabeth B. Davidow DVM  DACVECC 《Journal of Veterinary Emergency and Critical Care》2023,33(5):567-576

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Genetic and non-genetic factors influencing KLH binding natural antibodies and specific antibody response to Newcastle disease in Kenyan chicken populations     

Sophie Miyumo  Chrilukovian B. Wasike  Evans D. Ilatsia  Jörn Bennewitz  Mizeck G. Chagunda 《Zeitschrift für Tierzüchtung und Züchtungsbiologie》2023,140(1):106-120

This study aimed at investigating the influence of genetic and non-genetic factors on immune traits to inform on possibilities of genetic improvement of disease resistance traits in local chicken of Kenya. Immune traits such as natural and specific antibodies are considered suitable indicators of an individual's health status and consequently, used as indicator traits of disease resistance. In this study, natural antibodies binding to Keyhole Limpet Hemocyanin (KLH-NAbs) was used to measure general disease resistance. Specific antibodies binding to Newcastle disease virus (NDV-IgG) post vaccination was used to measure specific disease resistance. Titers of KLH-NAbs isotypes (KLH-IgM, KLH-IgG and KLH-IgA) and NDV-IgG were measured in 1,540 chickens of different ages ranging from 12 to 56 weeks. A general linear model was fitted to determine the effect of sex, generation, population type, phylogenetic cluster, line, genotype and age on the antibody traits. A multivariate animal mixed model was fitted to estimate heritability and genetic correlations among the antibody traits. The model constituted of non-genetic factors found to have a significant influence on the antibody traits as fixed effects, and animal and residual effects as random variables. Overall mean (±SE) concentration levels for KLH-IgM, KLH-IgG, KLH-IgA and NDV-IgG were 10.33 ± 0.04, 9.08 ± 0.02, 6.00 ± 0.02 and 10.12 ± 0.03, respectively. Sex, generation and age (linear covariate) significantly (p < 0.05) influenced variation across all the antibody traits. Genotype effects (p < 0.05) were present in all antibody traits, apart from KLH-IgA. Interaction between generation and line was significant (p < 0.05) in KLH-IgM and NDV-IgG while nesting phylogenetic cluster within population significantly (p < 0.05) influenced all antibody traits, apart from KLH-IgA. Heritability estimates for KLH-IgM, KLH-IgG, KLH-IgA and NDV-IgG were 0.28 ± 0.08, 0.14 ± 0.06, 0.07 ± 0.04 and 0.31 ± 0.06, respectively. There were positive genetic correlations (0.40–0.61) among the KLH-NAbs while negative genetic correlations (−0.26 to −0.98) were observed between the KLH-NAbs and NDV-IgG. Results from this study indicate that non-genetic effects due to biological and environmental factors influence natural and specific antibodies and should be accounted for to reduce bias and improve accuracy when evaluating the traits. Subsequently, the moderate heritability estimates in KLH-IgM and NDV-IgG suggest selection possibilities for genetic improvement of general and specific immunity, respectively, and consequently disease resistance. However, the negative correlations between KLH-NAbs and NDV-IgG indicate the need to consider a suitable approach that can optimally combine both traits in a multiple trait selection strategies.  相似文献   

Clinicopathologic and gastrointestinal effects of administration of prednisone,prednisone with omeprazole,or prednisone with probiotics to dogs: A double-blind randomized trial     

Mariola B. Rak  Tamberlyn D. Moyers  Joshua M. Price  Jacqueline C. Whittemore 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(2):465-475

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Comparison of two postoperative complication grading systems after treatment of stifle and shoulder instability in 68 dogs     

Faolain M. Barrett BVM&S  Jason A. Bleedorn DVM MS  DACVS-SA  Kyle D. Hutcheson DVM  DACVS-SA  Bryan T. Torres DVM PhD  DACVS-SA  DACVSMR  Derek B. Fox DVM  PhD  DACVS 《Veterinary surgery : VS》2023,52(1):98-105

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