Assessment of the potential toxicity of a poison for rabbits, pindone (2-pivalyl 1, 3 indandione), to domestic animals     

GR MARTIN  RJ SUTHERLAND†  ID ROBERTSON†  WE KIRKPATRICK  DR KING  PJ HOOD† 《Australian veterinary journal》1991,68(7):241-243

The toxicity of pindone, a rabbit poison, to horses, cattle, goats, chickens, dogs and cats was investigated, using extension of prothrombin time (PT) as an index of poisoning. The daily dose of pindone, administered for 5 days, ranged from 0.3 mg/kg for dogs to 2.5 mg/kg for chickens. This range of dose rates was considered to be indicative of the worst possible case that could arise following a campaign of baiting for rabbits. Although significant elevations in PT (more than double baseline values) were noted in all species other than horses, clinical signs of anticoagulant poisoning were not observed in any of the species tested. From the observed PT, cattle and cats appeared to be the most susceptible, and horses the least susceptible, to pindone toxicity. The half-lives of the elevated PT were calculated as 3.1 days for cattle, 2.8 days for goats and chickens, 1.9 days for horses and dogs and less than one day for cats. It is proposed that these half-lives can be used as a guide for determining the duration of treatment of pindone-affected animals.  相似文献   

Isolation of Mycobacterium avium subsp paratuberculosis from the semen of rams with clinical Johne''s disease     

J EPPLESTON  RJ WHITTINGTON 《Australian veterinary journal》2001,79(11):776-777

  相似文献   

Detection of Clostridium botulinum types C and D toxin by ELISA   总被引：3，自引：0，他引：3  

RJ THOMAS 《Australian veterinary journal》1991,68(3):111-113

An ELISA to detect Clostridium botulinum type D toxin was developed using polyclonal antibodies to a semi-purified toxic complex of the neurotoxin. Sensitivity of the ELISA for detecting type C and type D toxin compared with mouse inoculation was 70% and specificity 96% on samples from animals with botulism diagnosed on clinical signs and herd history. However, both mouse inoculation and the ELISA failed to detect toxin in many animals with a presumptive diagnosis of botulism. Some cross-reaction was seen with Clostridium novyi type A, but not with other clostridial species. While the ELISA described here cannot replace mouse inoculation for the diagnosis of botulism, it is a useful additional test.  相似文献   

Observations on the indirect transmission of virulent ovine footrot in sheep yards and its spread in sheep on unimproved pasture     

RJ WHITTINGTON 《Australian veterinary journal》1995,72(4):132-134

SUMMARY: Virulent ovine footrot was transmitted accidentally to a group of 23 adult Merino sheep (flock B) after holding for 1 hour in sheep yards, which earlier the same day had contained another flock (flock A) with < 1% prevalence of sheep with footrot lesions. Sheep in flock B were rendered susceptible to virulent footrot by grazing 600 mm high unimproved pasture dominated by paspalum ( Paspalum dilatatum ) and kangaroo grass ( Themeda australis ) during warm, humid and wet weather. In addition to moisture, interdigital abrasions caused by the pasture might have predisposed the interdigital skin to infection with Dichelobacter nodosus .  相似文献   

Restriction-endonuclease analysis of Australian isolates of Leptospira interrogans serovar hardjo from cattle with agalactia and abortion   总被引：1，自引：0，他引：1  

S. DJORDJEVIC  M. HORNITZKY  AD ROSS  RJ WHITTINGTON 《Australian veterinary journal》1993,70(3):98-100

SUMMARY Polyacrylamide gel electrophoresis and agarose gel electrophoresis were used to resolve restriction endonuclease digests of 20 Australian isolates of Leptospira interrogans cultured from urine samples of cattle with agalactia and abortion. The restriction endonuclease profiles of 19 isolates closely matched the profiles of L interrogans serovar hardjo subtype hardjobovis reference strains. The remaining isolate had a different restriction profile from subtype hardjobovis and subtype hardjoprajitno reference strains and was serologically identified as serovar pomona. Silver staining of polyacrylamide gels gave enhanced resolution of restriction fragments compared with the traditional method of ethidium bromide staining of agarose gels.  相似文献   

Investigation of a second focus of equine morbillivirus infection in coastal Queensland   总被引：6，自引：0，他引：6  

RJ ROGERS  IC DOUGLAS  FC BALDOCK  RJ GLAVILLE  KT SEPPANEN  LJ GLEESON  PN SELLECK  KJ DUNN 《Australian veterinary journal》1996,74(3):243-244

  相似文献   

Investigations into the toxicity of Echium plantagineum in sheep: 1. Field grazing experiments     

JT SEAMAN  WS TURVEY  SJ OTTAWAY  AR GILMOUR  RJ DIXON† 《Australian veterinary journal》1989,66(9):279-285

A field grazing trial was undertaken to monitor the health and production of crossbred sheep grazing pasture where Echium plantagineum constituted a considerable proportion of the available forage. The trial, conducted for 19 months over successive grazing seasons, demonstrated a significant difference in production, with sheep on the E. plantagineum pasture being lighter and growing less wool compared with sheep on Echium-free pasture. No mortalities involving pyrrolizidine alkaloid poisoning were recorded in sheep grazing E. plantagineum, although there was histological evidence of moderately severe liver damage associated with high liver copper concentrations in at least one sheep following the grazing of large quantities of the plant.  相似文献   

Comparison of immunogenicity and virulence between Babesia bigemina parasites from continuous culture and from a splenectomised calf   总被引：1，自引：0，他引：1  

WK. JORGENSEN  AJ. DE. VOS  RJ. DALGLIESH † 《Australian veterinary journal》1989,66(11):371-372

  相似文献   

An outbreak of botulism in a deer herd in Queensland     

P. CHAMBERLAIN  RJ THOMAS† 《Australian veterinary journal》1995,72(11):427-428

  相似文献   

Premature farrowings caused by feeding cottonseed meal   总被引：1，自引：0，他引：1  

RJ LOVE  AJ PEACOCK  G EVANS † 《Australian veterinary journal》1990,67(6):223-226

Increasing the level of cottonseed meal (CSM) in sow diets from less than 5% to 10% increased the incidence of premature farrowings (gestation length less than 111 days) from 1.1% to 2.7% (p less than 0.001) and reduced the mean gestation length from 114.07 +/- 1.53 to 113.70 +/- 1.59 days (p less than 0.0001). Survival of piglets born prematurely was poor. After removal of CSM from the diet there was a residual effect lasting several weeks before the gestation length returned to normal. Experimental feeding of diets containing 20% and 40% CSM to small groups of sows caused significant shortening of gestation length and 3 of 26 sows fed 40% CSM farrowed prematurely. The mechanism by which CSM causes this effect has yet to be determined.  相似文献