Prof. Dipl. Ing. Dr. Dr. h. c. Leo Tschermak zum Gedenken     

Hannes Mayer 《European Journal of Forest Research》1969,88(1):378-379

Ohne Zusammenfassung  相似文献   

Behavioral Abnormalities in Lagotto Romagnolo Dogs with a History of Benign Familial Juvenile Epilepsy: A Long‐Term Follow‐Up Study          下载免费PDF全文

T.S. Jokinen  K. Tiira  L. Metsähonkala  E.H. Seppälä  A. Hielm‐Björkman  H. Lohi  O. Laitinen‐Vapaavuori 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2015,29(4):1081-1087

Background

Lagotto Romagnolo (LR) dogs with benign juvenile epilepsy syndrome often experience spontaneous remission of seizures. The long‐term outcome in these dogs currently is unknown. In humans, behavioral and psychiatric comorbidities have been reported in pediatric and adult‐onset epilepsies.

Hypothesis/Objectives

The objectives of this study were to investigate possible neurobehavioral comorbidities in LR with a history of benign familial juvenile epilepsy (BFJE) and to assess the occurrence of seizures after the remission of seizures in puppyhood.

Animals

A total of 25 LR with a history of BFJE and 91 control dogs of the same breed.

Methods

Owners of the LR dogs in the BFJE and control groups completed an online questionnaire about each dog''s activity, impulsivity, and inattention. Principal component analysis (PCA) served to extract behavioral factors from the data. We then compared the scores of these factors between the 2 groups in a retrospective case–control study. We also interviewed all dog owners in the BFJE group by telephone to inquire specifically about possible seizures or other neurological problems after remission of seizures as a puppy.

Results

Lagotto Romagnolo dogs with BFJE showed significantly higher scores on the factors Inattention and Excitability/Impulsivity than did the control group (P = .003; P = .021, respectively). Only 1 of the 25 BFJE LR exhibited seizures after remission of epilepsy in puppyhood.

Conclusions and Clinical Importance

Although the long‐term seizure outcome in BFJE LR seems to be good, the dogs exhibit behavioral abnormalities resembling attention deficit hyperactivity disorder (ADHD) in humans, thus suggesting neurobehavioral comorbidities with epilepsy.  相似文献   

Breed Differences in Natriuretic Peptides in Healthy Dogs     

K. Sjstrand  G. Wess  I. Ljungvall  J. Hggstrm  A‐C. Merveille  M. Wiberg  V. Gouni  J. Lundgren Willesen  S. Hans  A‐S. Lequarr  L. Mejer Srensen  J. Wolf  L. Tiret  M. Kierczak  S. Forsberg  K. McEntee  G. Battaille  E. Seppl  K. Lindblad‐Toh  M. Georges  Hannes Lohi  V. Chetboul  M. Fredholm  K. Hglund 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2014,28(2):451-457

Background

Measurement of plasma concentration of natriuretic peptides (NPs) is suggested to be of value in diagnosis of cardiac disease in dogs, but many factors other than cardiac status may influence their concentrations. Dog breed potentially is 1 such factor.

Objective

To investigate breed variation in plasma concentrations of pro‐atrial natriuretic peptide 31‐67 (proANP 31‐67) and N‐terminal B‐type natriuretic peptide (NT‐proBNP) in healthy dogs.

Animals

535 healthy, privately owned dogs of 9 breeds were examined at 5 centers as part of the European Union (EU) LUPA project.

Methods

Absence of cardiovascular disease or other clinically relevant organ‐related or systemic disease was ensured by thorough clinical investigation. Plasma concentrations of proANP 31‐67 and NT‐proBNP were measured by commercially available ELISA assays.

Results

Overall significant breed differences were found in proANP 31‐67 (P < .0001) and NT‐proBNP (P < .0001) concentrations. Pair‐wise comparisons between breeds differed in approximately 50% of comparisons for proANP 31‐67 as well as NT‐proBNP concentrations, both when including all centers and within each center. Interquartile range was large for many breeds, especially for NT‐proBNP. Among included breeds, Labrador Retrievers and Newfoundlands had highest median NT‐proBNP concentrations with concentrations 3 times as high as those of Dachshunds. German Shepherds and Cavalier King Charles Spaniels had the highest median proANP 31‐67 concentrations, twice the median concentration in Doberman Pinschers.

Conclusions and Clinical Importance

Considerable interbreed variation in plasma NP concentrations was found in healthy dogs. Intrabreed variation was large in several breeds, especially for NT‐proBNP. Additional studies are needed to establish breed‐specific reference ranges.  相似文献   

Fate of heavy metals in a strongly acidic shooting‐range soil: small‐scale metal distribution and its relation to preferential water flow     

Lars A. Knechtenhofer  Irene O. Xifra  Andreas C. Scheinost  Hannes Flühler  Ruben Kretzschmar 《植物养料与土壤学杂志》2003,166(1):84-92

To assess the mobility of Pb and associated metals in a highly contaminated shooting range soil (Losone, Ticino, Switzerland), we investigated the spatial distribution of the metals and their relation to preferential water flow paths. A 2.2 m² plot located 40 m behind the stop butt was irrigated with a solution containing bromide and Brilliant Blue, a slightly sorbing dye. A soil profile 50 cm in width was sampled down to 80 cm with a spatial resolution of 2.5 cm, resulting in 626 samples. Concentrations of elements (12 ≤ Z ≤ 92) were determined by energy‐dispersive Xray fluorescence spectrometry, and Brilliant Blue concentrations were determined with a chromameter. In the acidic (pH 3), organic matter‐rich, well drained Dystric Cambisol, maximum concentrations of 80.9 g kg^‐1 Pb, 4.0 g kg^‐1 Sb, and 0.55 g kg^‐1 Cu were measured in the topsoil. Within 40 cm soil depth, however, Pb, Sb, and Cu approached background concentrations of 23 mg kg^‐1, 0.4 mg kg^‐1, and 9.4 mg kg^‐1, respectively. The even horizontal distribution and the steep gradient along soil depth indicate tight metal binding in the topsoil, and a fairly homogeneous transport front. In contrast, water flow through the profile was highly heterogeneous. In the uppermost 20 cm, preferential flow was initiated by heterogeneous infiltration at the soil surface, but had no influence on metal distribution. Below 20 cm, however, preferential flow originated from larger tree roots, and metal concentrations were significantly elevated along these macropores. Spatial distributions of Pb, Sb, and Cu were similar, suggesting that all three metals are strongly retained in the topsoil and transported along preferential water flow paths in the subsoil.  相似文献   

Identifying, understanding, and describing spatial processes in agricultural landscapes — four case studies     

Ole Wendroth  Peter Jürschik  K. Christian Kersebaum  Hannes Reuter  Chris van Kessel  Donald R. Nielsen 《Soil & Tillage Research》2001,58(3-4):113-127

To evaluate the quality of the ecosystem and for making resources and land management decisions landscapes have to be assessed quantitatively. For a better understanding of landscape processes and their characterization, the analysis of the inherent variability is a major factor. Four case studies in which problems associated with landscape analysis are discussed. Spatial processes remain a main focus, as their analysis provides information on the relation between relevant state variables in agricultural landscapes. Variogram analysis showed that mineral soil nitrogen (N_min) sampled in a field at different scales, domains, and times is an instationary spatial process. Spatial association of grain yield, soil index and remotely sensed vegetation index may not be identifiable from kriged contour maps as local coincidence may be obscured behind classified areas. Crop yield in subsequent years and remotely sensed information are not related if a unique response is assumed. An alternative data stratification procedure is described here for the identification of different response functions in agricultural ecosystems. Processes of crop yield and underlying variables are described in autoregressive state-space models. This technique incorporates both deterministic and stochastic relations between different variables and is based on relative changes in space.  相似文献   

A C. elegans CLIC-like protein required for intracellular tube formation and maintenance     

Berry KL  Bülow HE  Hall DH  Hobert O 《Science (New York, N.Y.)》2003,302(5653):2134-2137

The Caenorhabditis elegans excretory canal is composed of a single elongated and branched cell that is tunneled by an inner lumen of apical character. Loss of the exc-4 gene causes a cystic enlargement of this intracellular tube. exc-4 encodes a member of the chloride intracellular channel (CLIC) family of proteins. EXC-4 protein localizes to various tubular membranes in distinct cell types, including the lumenal membrane of the excretory tubes. A conserved 55-amino acid domain enables EXC-4 translocation from the cytosol to the lumenal membrane. The tubular architecture of this membrane requires EXC-4 for both its formation and maintenance.  相似文献   

ADAMTS17 mutation associated with primary lens luxation is widespread among breeds     

Gould D  Pettitt L  McLaughlin B  Holmes N  Forman O  Thomas A  Ahonen S  Lohi H  O'Leary C  Sargan D  Mellersh C 《Veterinary ophthalmology》2011,14(6):378-384

Primary lens luxation (PLL) is a well-recognized, painful and potentially blinding inherited ocular condition in dogs. We screened PLL-affected dogs of 30 different breeds, to identify those which carried a previously described c.1473+1 G>A mutation in ADAMTS17 that is associated with PLL in Miniature Bull terriers, Lancashire Heelers, and Jack Russell terriers. This ADAMTS17 mutation was identified in PLL-affected dogs from 14 additional breeds. PLL-affected dogs from some breeds (most notably the Shar pei and the Brittany spaniel) did not carry the G1473+1A ADAMTS17 mutation, indicating they must suffer from a genetically distinct form of the condition. We also estimated the frequency of this ADAMTS17 mutation in some of the breeds. Our findings indicate the mutation segregates in a large number of different breeds of dog, many of which are terriers or breeds with terrier co-ancestry, but some of which have more diverse origins. Our results also indicate that the mutation is present at high frequency within most of the breeds in which it segregates. In the miniature bull terrier breed estimates of mutation frequency ranged from 0.27 to 0.39, corresponding to 7.3-15.2% PLL-affected dogs in this breed. We also identified an increased risk of PLL associated with heterozygosity at ADAMTS17, suggesting that carriers carry a low risk of developing PLL.  相似文献   

DIAGNOSTIC ULTRASOUND IMAGING OF SOFT TISSUES IN THE BOVINE DISTAL LIMB   总被引：4，自引：0，他引：4  

Johann  Kofler  Dr. Med. Vet  Hannes K.  Edinger  Dr. Med. Vet. 《Veterinary radiology & ultrasound》1995,36(3):246-252

In this study sonographic images of healthy flexor tendons, digital flexor tendon sheaths, metacarpophalangeal and metatarsophalangeal joints, and proximal and distal interphalangeal joints of the bovine limb were made. Then, synovial cavities in cadavers were filled with the necessary amount of fluid to make the lumina visible sonographically. After injecting 30–40 ml of saline solution into the digital flexor tendon sheath and into the metacarpophalangeal and metatarsophalangeal joints, or 8 ml in the proximal interphalangeal joint and 10 ml in the distal interphalangeal joint, the pouches of these synovial cavities were clearly demarcated. Afterwards, the sonographic image of synovial cavities distended by various inflammatory content were described. When the sonographic findings were compared to the findings in clinical patients, centesis and intraoperative procedures, there appeared to be a relationship as to the extent and location of the disorders as well as to the nature of the synovial effusion. Finally, we identified which planes on diseased bovine distal limbs were appropriate for obtaining optimal sonographic images.  相似文献   

III. Buchbesprechungen     

Hannes Mayer  J. Jung  W. Schwenke  Rehfuess  F. Bichlmaier  R. Kennel 《European Journal of Forest Research》1966,85(3-4):121-128

  相似文献   

Immune gene diversity in grey wolves (Canis lupus)     

A.K. Niskanen  L. Kennedy  I. Kojola  H. Lohi  M. Ruokonen  J. Aspi 《Journal of Veterinary Behavior: Clinical Applications and Research》2013,8(4):e33-e34

  相似文献