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61.
A 2-year-old intact miniature pinscher bitch that had been on a bones and raw foods diet since birth showed no signs of estrus despite a 40-day course of cabergoline. Elevated levels of thyroxine were detected in the serum (51 nmol/L) and in the juice of the meat (183 nmol/L) fed to the dog. Change in diet and treatment with oral cabergoline resulted in signs of proestrus in 13 d, pregnancy, and normal birth of 5 puppies.  相似文献   
62.
Accurate definition of respiratory health in pigs is an important problem for swine producers and veterinarians. In an approach to identify potential biomarkers, two-dimensional gel electrophoresis and mass spectrometry on bronchoalveolar lavage fluid (BALF)-derived proteins from pigs experimentally infected with Actinobacillus pleuropneumoniae were performed at different time points post infection. Mock-infected pigs were used as a control. It was shown that the antimicrobial peptides, prophenin-2 and PR-39, and the calcium-binding protein calgranulin C were reproducibly upregulated in BALF of pigs chronically infected with A. pleuropneumoniae. Concentrations of PR-39 were significantly (p<0.05) increased in BALF (median of 4.8 nM) but not in serum (median of 2.5 nM) on day 21 after infection. A Receiver Operating Characteristics (ROC) plot showed that PR-39 in BALF is an accurate and easily accessible marker to detect clinically healthy pigs convalescent from an experimental A. pleuropneumoniae infection. These results imply that PR-39 might have a potential as a general biomarker to determine porcine respiratory health.  相似文献   
63.
Urine specific gravity (Usg) and urine osmolality (Uosm) are used routinely to assess renal concentrating ability, but limited data on these variables are available for healthy dogs. Consequently, we studied the intra- and interindividual variations in Usg and Uosm in healthy dogs as well as the influence of age and gender on these variables. Dogs were selected for health and anestrus in female dogs through the use of a detailed questionnaire. Eighty-nine owners collected morning and evening urine samples from their dogs on 2 consecutive days. In 8 dogs in which the Uosm of different samples varied more than 50%, owners collected urine for 24 hours at 2-hour intervals during the day and at 4-hour intervals at night. The possible effect of changes in adrenocortical function with age was assessed by measurements of urinary corticoid/creatinine (C/C) ratios. Among all samples, Uosm ranged from 161 to 2,830 mOsm/kg and Usg from 1.006 to > 1.050. In the morning, Uosm (1,541 ± 527 mOsm/kg, range 273–2,620 mOsm/kg) and Usg (1.035 ± 0.010, range 1.009- > 1.050) were higher than in the evening (Uosm 1,400 ± 586 mOsm/kg, range 161–2,830 mOsm/kg; Usg 1.031 ± 0.012, range 1.006- > 1.050). The interindividual coefficient of variation in Uosm was 34.2% for morning urine samples and 41.9% for evening samples. In 8 dogs with large differences in urine concentration, there were 2– to 3-fold increases or decreases in Uosm during the day, and the intraindividual coefficient of variation was 33.0%. There was no relation between gender and urine concentration. Urine concentration in both the morning and evening samples decreased with age. Urinary corticoid/creatinine ratios did not change with age. It can be concluded that Uosm and Usg vary widely among healthy dogs. Urine concentration is generally lower in the evening than in the morning and is not related to gender. Urine concentration decreases with age, and this cannot be ascribed to an associated increase in endogenous corticoids. In some dogs, Uosm varies widely during the day, with an intraindividual coefficient of variation approaching the interindividual coefficient of variation. This may be regarded as a biologic variation but also could represent an early undi-agnosed clinical abnormality.  相似文献   
64.
The capercaillie Tetrao urogallus has become endangered in central Europe, most probably as a result of habitat changes. Breeding ecology was studied by following radio-tagged hens through egg-laying, incubation, and chick-rearing between 1988 and 1992. Loss of chicks rather than nests was the main determinant of reproductive success. All adult hens incubated, two-thirds of the nests hatched, and one-fifth of the chicks survived until autumn. Both nests and broods were mostly found in habitats with rich ground vegetation. Nest cover was probably a major factor for hatching success. Brood home ranges averaged 148 ha during the period from hatching to late summer. Broods preferred old forest stands with rich ground vegetation and high invertebrate abundance, which occur under moderate canopy cover. Bilberry Vaccinium myrtillus was an essential feature for brood habitat at forest stand, home range, and landscape scale, and should therefore be a major goal for capercaillie habitat management in central Europe.  相似文献   
65.
Zusammenfassung Es wurden 1300 Sommergersten des Sortiments Gatersleben mit 11 Rassen vonErysiphe graminis hordei geprüft.Als hochresistent gegen alle Rassen erwiesen sich 48 (4%) der Sorten (Tab. 2), als mäßig resistent weitere 24 Sorten (Tab. 4). Resistent gegen einen Teil der Rassen zeigten sich 83, gleich 6%, der geprüften Gersten (Tab. 3). In weiteren 41 Sippen lagen Gemische von resistenten und anfälligen Pflanzen vor. Als anfällig wurden 85% dieses Sortimentes bewertet.
Resistance characters in the barley and wheat collection Gatersleben
Summary A total of 1300 spring barley varieties of the Gatersleben collection was tested with 11 races ofErysiphe graminis hordei.Fourty-eight varieties (table 2) or nearly 4 per cent of the total proved to be highly and 24 varieties (table 4) to be moderately resistant to all these races. Resistance to some of the races was shown by 83 varieties or more than 6 per cent of the collection tested (table 3). Mixtures of resistant with susceptible plants were found in 41 samples. About 85 per cent of the total was classified as susceptible.

1300 11 . 48 (4%; . . 2), — 24 (. 4). 83 6% (. 3). 41 . 85% .
  相似文献   
66.
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68.
A 1‐year‐old male French Lop rabbit (Oryctolagus cuniculus) was presented with a sudden onset of hyporexia. Physical examination revealed cranial abdominal discomfort. Liver enzymes were elevated on serum biochemistry profile. Abdominal radiographs showed diffusely gas‐dilated small intestinal loops. On abdominal ultrasound, a lobe in the right aspect of the liver was hypoechoic with rounded margins and was surrounded by hyperechoic fat and anechoic fluid. Contrast‐enhanced ultrasonography showed complete lack of perfusion in the abnormal right liver lobe. Exploratory laparotomy revealed torsion of the quadrate liver lobe. Diffuse coagulation necrosis was noted on histopathologic examination. The rabbit fully recovered after surgery.  相似文献   
69.
This retrospective study was performed to investigate the diagnostic efficacy of the chemiluminometric ACTH-measurement to differentiate between pituitary and adrenal dependent hyperadrenocorticism (HAC) in dogs. 49 dogs with pituitary HAC, 10 dogs with adrenal HAC and 1 dog with a combination of both pathologies were included. Dogs with HAC like symptoms, where HAC had been ruled out, served as controls (n = 18). All dogs with adrenal HAC, as well as 9 dogs with pituitary HAC had an ACTH concentration below the detection limit of 2.2 pmol/l (10 pg/dl) plasma. Using 2.2 pmol/l as a cut-off the sensitivity and specificity to diagnose pituitary HAC was 0.82 (95 % CI 0.686 - 0.914) and 1 (95 % CI 0.692 - 1), respectively. With the help of the chemiluminometric assay, a correct classification was possible in 85 % of patients with HAC. As an ACTH-concentration below the detection limit was found in dogs with adrenal as well as pituitary HAC, additional discriminatory tests are necessary in these cases.  相似文献   
70.
Aspergillus fumigatus is a common pathogen in poultry and captive wild birds and an emerging opportunistic fungal pathogen in immunocompromised humans. Although invasive aspergillosis is frequently reported in free-ranging wild birds, the incidence and epidemiology of the disease in a natural setting is unknown. We recently reported endemic outbreaks of invasive aspergillosis at white stork nesting sites close to human habitation in Germany with significant subsequent breeding losses. Therefore, we hypothesized that A. fumigatus strains with higher virulence in birds may have evolved in this environment and performed the first epidemiological analysis of invasive aspergillosis in free-ranging wild birds. Sixty-one clinical and environmental A. fumigatus isolates from six affected nesting sites were genotyped by microsatellite analysis using the STRAf-assay. The isolates showed a remarkable high genomic diversity and, contrary to the initial hypothesis, clinical and environmental isolates did not cluster significantly. Interestingly, storks were infected with two to four different genotypes and in most cases both mating types MAT-1.1 and MAT-1.2 were present within the same specimen. The majority of selected clinical and environmental strains exhibited similar virulence in an in vivo infection model using embryonated chicken eggs. Noteworthy, virulence was not associated with one distinct fungal mating type. These results further support the assumption that the majority of A. fumigatus strains have the potential to cause disease in susceptible hosts. In white storks, immaturity of the immune system during the first three weeks of age may enhance susceptibility to invasive aspergillosis.  相似文献   
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