Computed tomographic findings in 205 dogs with clinical signs compatible with middle ear disease: a retrospective study          下载免费PDF全文

Audrey Belmudes  Charline Pressanti  Paul Y. Barthez  Eloy Castilla‐Castaño  Lionel Fabries  Marie C. Cadiergues 《Veterinary dermatology》2018,29(1):45-e20

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Psychology. Is she conscious?     

Naccache L 《Science (New York, N.Y.)》2006,313(5792):1395-1396

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Climatic significance of glacier retreat and rockglaciers re-assessed in the light of cosmogenic dating and weathering rind thickness in Clarée valley (Briançonnais,French Alps)     

Etienne Cossart  Monique Fort  Didier Bourles  Julien Carcaillet  Romain Perrier  Lionel Siame  Régis Braucher 《CATENA》2010

Recent advances in geochronology provide opportunities to identify the glacial and periglacial sequences in mountain area. In this paper, we focus on the Upper Durance catchment (Southern French Alps), in the Clarée valley, where no absolute chronological benchmark was defined. Glacial remnants and periglacial features were investigated, integrated within a chronological scenario thanks to relative (weathering rind thickness) and absolute (CRE technique) dates. We find evidence of the existence of a Late-Glacial valley glacier, that has never been reported before. Then the upper valleys became ice-free during a period corresponding to the Early-Holocene Climate Optimum, whereas two sequences of cirque glaciation are identified during the second half of the Holocene. We also show evidence of three main generations of rockglaciers, which also mainly developed during the second half of the Holocene, probably at the end of the Subboreal period. The location and the altitudes of rockglaciers are strongly dependent on the geomorphic setting (especially the location of the sediment sources), hence complicating their palaeo-climatic interpretations.  相似文献   

Acromyrmex octospinosus (Hymenoptera: Formicidae) management. Part 1: Effects of TRAMIL's insecticidal plant extracts     

Boulogne I  Germosen-Robineau L  Ozier-Lafontaine H  Jacoby-Koaly C  Aurela L  Loranger-Merciris G 《Pest management science》2012,68(2):313-320

BACKGROUND: Leaf‐cutting ants are considered to be one of the most important pest species of the New World. Until now, control strategies against these leaf‐cutting ants have mainly been synthetic chemicals. The aim of the present study was to test the action of several plant extracts quoted as an example by TRAMIL participative surveys for their insecticidal properties on adult major workers of Acromyrmex octospinosus. Three tests were used to that end: contact toxicity, repellent test and ingestion bioassay. Six traditional plant uses recommended by interviewed people in surveys were tested: (1) maceration of Mammea americana fresh crushed seeds; (2) decoction of Nerium oleander fresh leaves; (3) Nerium oleander dried leaf water juice; (4) decoction of Nicotiana tabacum dried leaves; (5) Trichillia pallida dried leaf water juice; (6) decoction of Rollinia mucosa dried seeds. RESULTS: Two plant extracts with contact toxicity (Mammea americana and Nicotiana tabacum), six plant extracts with repellent activity and four plant extracts with ingestion toxicity (Mammea americana, Nicotiana tabacum and both extracts of Nerium oleander) were found. CONCLUSION: The data presented in this study showed that plant extracts cited by TRAMIL ethnopharmacological surveys have the potential to control the leaf‐cutting ant, Acromyrmex octospinosus. In particular, the Mammea americana extract, with its natural low repellent effect and its high toxicity by ingestion, and Nerium oleander extracts, with their natural delay action, are possibly the best extracts for the control of these ants. Copyright © 2011 Society of Chemical Industry  相似文献   

Viewpoint - laboratory animal ophthalmology     

Rubin LF 《Veterinary ophthalmology》2002,5(3):142-142

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Pseudomonas sax genes overcome aliphatic isothiocyanate-mediated non-host resistance in Arabidopsis     

Fan J  Crooks C  Creissen G  Hill L  Fairhurst S  Doerner P  Lamb C 《Science (New York, N.Y.)》2011,331(6021):1185-1188

Most plant-microbe interactions do not result in disease; natural products restrict non-host pathogens. We found that sulforaphane (4-methylsulfinylbutyl isothiocyanate), a natural product derived from aliphatic glucosinolates, inhibits growth in Arabidopsis of non-host Pseudomonas bacteria in planta. Multiple sax genes (saxCAB/F/D/G) were identified in Pseudomonas species virulent on Arabidopsis. These sax genes are required to overwhelm isothiocyanate-based defenses and facilitate a disease outcome, especially in the young leaves critical for plant survival. Introduction of saxCAB genes into non-host strains enabled them to overcome these Arabidopsis defenses. Our study shows that aliphatic isothiocyanates, previously shown to limit damage by herbivores, are also crucial, robust, and developmentally regulated defenses that underpin non-host resistance in the Arabidopsis-Pseudomonas pathosystem.  相似文献   

Minimizing the Treatments Required to Determine the Responses of Different Crop Genotypes to Potassium Supply     

Philip J. White  Tahei Kawachi  Jacqueline A. Thompson  Gladys Wright  Lionel X. Dupuy 《Communications in Soil Science and Plant Analysis》2016,47(22):104-111

ABSTRACT

Crop genotypes that make best use of potassium (K) fertilizers can promote agricultural sustainability. However, screening germplasm collections for responses to K fertilizers is often laborious and expensive. To reduce costs, the number of K fertilizer treatments required to identify better genotypes should be minimized. This might be achieved by exploiting the mathematical relationships between biomass, plant K content, and K supply. This study employed 14 barley (Hordeum vulgare L.) genotypes growing in a hydroponics system that allowed the K supply to roots to be controlled through the K concentration in a flowing solution. It sought to determine the minimal number of treatments required to model the relationships between (a) shoot biomass and K supply, (b) plant K content and K supply, and (c) shoot biomass and plant K content. The relationships between (a) shoot biomass and K supply and (b) plant K content and K supply for any given genotype could be fitted by Michaelis–Menten equations and each of these could be estimated from data obtained at two, appropriately-chosen, rates of K supply. The relationship between shoot biomass and plant K content could be estimated from these relationships. However, the optimum K supply required for accurate estimates differed between genotypes and whether shoot biomass or plant K content was to be estimated. It is, therefore, suggested that the relationships between shoot biomass, plant K content, and K supply might best be determined from measurements of biomass and K content at three, carefully-selected, rates of K supply.  相似文献   

Are urban forests ecological traps for understory birds? An examination using Northern cardinals     

Lionel F.V. Leston 《Biological conservation》2006,131(4):566-574

Many studies have reported increased numbers of certain synanthropic species in urbanizing landscapes, but few have evaluated if urban habitats constitute ecological traps for these species. The Northern cardinal (Cardinalis cardinalis) was used as a model species to evaluate if urban riparian forests might act as ecological traps for understory-nesting birds. Cardinals were surveyed within 2-ha riparian forest plots within rural (n = 6) and urban (n = 6) landscapes in Ohio USA during breeding and non-breeding seasons 2003-2005. Cues used by cardinals to select habitats were identified based on measurements surrounding 219 nests and in 106 randomly-located plots and 96 systematically-located plots. Productivity of 161 cardinal pairs and survival of 180 adults were monitored from late March-September, 2003-2005. Cardinals were 1.7× (in the breeding season) to nearly 4× (in non-breeding season) more abundant in urban than rural forests, and the results suggest that these differences in abundance stemmed from urban-associated changes in habitat and microclimate features used by cardinals to select habitats. Most notably, cardinals were strongly associated with dense understory vegetation and warmer minimum January temperatures, both of which were promoted as urban development increased within the landscapes surrounding riparian forests. Although other studies suggest mismatches between the habitat cues used by cardinals and how those features affect nesting success (e.g., higher nest predation in exotic shrubs), these results provide no evidence that urban forests were acting as ecological traps for cardinals. Instead, cardinals in urban and rural forests had similar numbers of nesting attempts, young fledged over the breeding season, and apparent annual survival rates. Thus, these findings do not support for the idea that urban forests in central Ohio represent ecological traps for synanthropic understory birds.  相似文献   

Nerve growth factor in dogs: Assessment of two immunoassays and selected ocular parameters following a nicergoline challenge per os     

Lionel Sebbag  Leah M. Moody  Rachel A. Allbaugh  Jonathan P. Mochel 《Veterinary ophthalmology》2020,23(1):199-204

Impairment of corneal nerves can result in the development of ocular surface diseases such as aqueous tear deficiency and neurotrophic keratopathy. This study investigates oral nicergoline, an α‐adrenoceptor antagonist shown to enhance endogenous secretion of nerve growth factor (NGF) by the lacrimal gland, as a potential therapy for these conditions. Five female spayed Beagle dogs received a 2‐week course of oral nicergoline (10 mg twice daily). Drug safety was evaluated with ophthalmic and physical examinations, blood pressure monitoring, bloodwork, and urinalysis. The effect of nicergoline on the ocular surface was assessed with corneal esthesiometry, Schirmer tear test‐1, and tear film breakup time. Drug effect on NGF levels was assessed by collecting tears and blood at baseline and completion of therapy using a bead‐based immunoassay and an enzyme‐linked immunosorbent assay. Although nicergoline was well tolerated in all dogs, it did not have a significant impact on corneal sensitivity, tear production, or tear stability. Of note, NGF was below the limit of quantification in all tear samples and was only detected in 8/20 serum samples with no significant difference between levels at baseline (189.4 ± 145.1 pg/mL) and completion of therapy (149.4 ± 79.4 pg/mL). Further validation of NGF analytical assays is warranted before nicergoline is investigated in clinical patients.  相似文献   

Hemocyte characteristics in families of oysters, Crassostrea gigas, selected for differential survival during summer and reared in three sites     

Christophe Lambert  Philippe Soudant  Lionel Dgremont  Maryse Delaporte  Jeanne Moal  Pierre Boudry  Frdric Jean  Arnaud Huvet  Jean-Franois Samain 《Aquaculture (Amsterdam, Netherlands)》2007,270(1-4):276-288

High variability among individuals is often encountered when hemocyte characteristics are measured in bivalves. Such variability is suspected to result partly from genetic factors. In this study, hemocyte characteristics of six families of Crassostrea gigas were compared by flow cytometry at one sampling date in October 2001. These families were obtained from a nested, half-sibling cross design, and reared from July to October 2001 at three sites distributed along the French Atlantic coast from north to south: Baie des Veys (Normandy), Rivière d'Auray (Brittany) and Ronce (Marennes-oléron Basin, Poitou Charentes).

Among the 15 measured hemocyte characteristics, production of reactive oxygen species (ROS) of untreated hemocytes (maintained in filtered sterile seawater) and treated hemocytes (zymosan at 20 particles per hemocyte, and with Vibrio sp. S322 at 50 bacteria per hemocyte) was the most notable differences between families. This supports the existence of a genetic basis, at least partly, for the hemocyte characteristics of oysters, and especially for ROS production.

Among the six families analyzed, three have shown high survival during summer (named as “resistant”, mean mortality 5.2%) and three experienced high mortality during summer (named as “susceptible”, 30.6% mean mortality). Families showing high or low survival to summer mortality had similar hemocyte characteristics, regardless of the environmental conditions or reproductive state. Resistant families were observed to have higher total hemocyte counts and lower production of ROS than susceptible families. Moreover, ROS production of hemocytes from susceptible families was diminished significantly more by pathogenic Vibrio than that of resistant families. However, this study demonstrates also that rearing site strongly affected the hemocyte characteristics of all families of oysters, most notably hemocyte concentration and morphology (size and granularity), production of reactive oxygen species (ROS), and susceptibility to the cytotoxic activity of the pathogenic Vibrio sp. S322 (50 bacteria/hemocyte). Food availability and reproductive state are the most probable explanations for the site differences observed. Finally, it appeared difficult to link oyster survival during summer mortality to hemocyte profiles evaluated at one sampling date; other relevant indicators would probably help explaining oyster survival during summer mortality events.  相似文献