Effects of two different anesthetic protocols on 64‐MDCT coronary angiography in dogs          下载免费PDF全文

Randi Drees  Rebecca A. Johnson  Marie Pinkerton  Alejandro Munoz Del Rio  Jimmy H. Saunders  Christopher J. François 《Veterinary radiology & ultrasound》2015,56(1):46-54

Heart rate is a major factor influencing diagnostic image quality in computed tomographic coronary artery angiography (MDCT‐CA), with an ideal heart rate of 60–65 beats/min in humans. The purpose of this prospective study was to compare effects of two different clinically applicable anesthetic protocols on cardiovascular parameters and 64‐MDCT‐CA quality in 10 healthy dogs. Scan protocols and bolus volumes were standardized. Image evaluations were performed in random order by a board‐certified veterinary radiologist who was unaware of anesthetic protocols used. Heart rate during image acquisition did not differ between protocols (P = 1), with 80.6 ± 7.5 bpm for protocol A and 79.2 ± 14.2 bpm for protocol B. Mean blood pressure was significantly higher (P > 0.05) using protocol B (protocol A 62.9 ± 9.1 vs. protocol B 72.4 ± 15.9 mmHg). The R‐R intervals allowing for best depiction of individual coronary artery segments were found in the end diastolic period and varied between the 70% and 95% interval. Diagnostic quality was rated excellent, good, and moderate in the majority of the segments evaluated, with higher scores given for more proximal segments and lower for more distal segments, respectively. Blur was the most commonly observed artifact and mainly affected the distal segments. No significant differences were identified between the two protocols for optimal reconstruction interval, diagnostic quality and measured length individual segments, or proximal diameter of the coronary arteries (P = 1). Findings indicated that, when used with a standardized bolus volume, both of these anesthetic protocols yielded diagnostic quality coronary 64‐MDCT‐CA exams in healthy dogs.  相似文献   

Disposition,behavioural and physiological effects of escalating doses of intravenously administered fentanyl to young foals          下载免费PDF全文

H. K. Knych  E. P. Steffey  H. C. Casbeer  M. M. Mitchell 《Equine veterinary journal》2015,47(5):592-598

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Bilateral renal dysplasia,hydronephrosis, and hydroureter in a septic neonatal foal     

Rebecca A. Gilday  Chris Wojnarowicz  Kimberly A. Tryon  Katharina L. Lohmann 《The Canadian veterinary journal. La revue veterinaire canadienne》2015,56(3):257-260

A Canadian warmblood foal treated for septic polyarthritis was diagnosed with bilateral congenital renal dysplasia, hydronephrosis, and hydroureter at 2 weeks of age based on abdominal ultrasound and postmortem examination. Intermittent abdominal pain throughout the course of treatment was attributed to hydronephrosis and hydroureter.  相似文献   

Longitudinal data collection of Mycobacterium avium subspecies Paratuberculosis infections in dairy herds: the value of precise field data     

Ynte H Schukken  Robert H Whitlock  Dave Wolfgang  Yrjo Grohn  Annabelle Beaver  JoAnn VanKessel  Mike Zurakowski  Rebecca Mitchell 《Veterinary research》2015,46(1)

Longitudinal infection data on Mycobacterium avium subspecies paratuberculosis (MAP) was collected on three dairy farms in Northeastern United States during approximately 10 years. Precise data on animal characteristics and animal location within farm were collected on these farms. Cows were followed over time with regard to MAP status during biannual fecal and serum sampling and quarterly serum sampling. Approximately 13 000 serum samples, 6500 fecal samples and 2000 tissue samples were collected during these years. Prevalence of positive samples was 1.4% for serological samples, 2.2% in fecal samples and 16.7% in tissue samples. Infection dynamics of MAP was studied and resulted in a number of potential changes in our understanding of MAP infection dynamics. First, a high prevalence of MAP infection was observed in these herds due to lifetime follow up of cows, including slaughter. Second, two distinctly different infection patterns were observed, so called non-progressors and progressors. Non-progressors were characterized by intermittent and low shedding of MAP bacteria and a virtual absence of a humoral immune response. Progressors were characterized by continuous and progressive shedding and a clearly detectable and progressive humoral immune response. Strain typing of MAP isolates on the three farms identified on two of three farms a dominant strain type, indicating that some strains are more successful in terms of transmission and infection progression. Continuous high quality longitudinal data collection turned out to be an essential tool in our understanding of pathobiology and epidemiology of MAP infections in dairy herds.  相似文献   

Pneumothorax following nerve stimulator‐guided axillary brachial plexus block in a dog          下载免费PDF全文

Rebecca J. Bhalla  Elizabeth A. Leece 《Veterinary anaesthesia and analgesia》2015,42(6):658-659

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Ten-year comparison of the influence of organic and conventional crop management practices on the content of flavonoids in tomatoes     

Mitchell AE  Hong YJ  Koh E  Barrett DM  Bryant DE  Denison RF  Kaffka S 《Journal of agricultural and food chemistry》2007,55(15):6154-6159

Understanding how environment, crop management, and other factors, particularly soil fertility, influence the composition and quality of food crops is necessary for the production of high-quality nutritious foods. The flavonoid aglycones quercetin and kaempferol were measured in dried tomato samples (Lycopersicon esculentum L. cv. Halley 3155) that had been archived over the period from 1994 to 2004 from the Long-Term Research on Agricultural Systems project (LTRAS) at the University of California-Davis, which began in 1993. Conventional and organic processing tomato production systems are part of the set of systems compared at LTRAS. Comparisons of analyses of archived samples from conventional and organic production systems demonstrated statistically higher levels (P < 0.05) of quercetin and kaempferol aglycones in organic tomatoes. Ten-year mean levels of quercetin and kaempferol in organic tomatoes [115.5 and 63.3 mg g(-1) of dry matter (DM)] were 79 and 97% higher than those in conventional tomatoes (64.6 and 32.06 mg g(-1) of DM), respectively. The levels of flavonoids increased over time in samples from organic treatments, whereas the levels of flavonoids did not vary significantly in conventional treatments. This increase corresponds not only with increasing amounts of soil organic matter accumulating in organic plots but also with reduced manure application rates once soils in the organic systems had reached equilibrium levels of organic matter. Well-quantified changes in tomato nutrients over years in organic farming systems have not been reported previously.  相似文献   

Retrieval of Additional Epinephrine from Adrenaclick-Style Epinephrine Autoinjectors     

Arun Ganti  Rebecca Pilkerton  Erika Falsgraf  Elizabeth Vanwert  Nathan Brouwer  Alexander Beyer  Brendan Byrne 《The Forestry Chronicle》2021,32(1):55-58

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Factors leading to spatiotemporal variability of soil moisture and turfgrass quality within sand-capped golf course fairways     

Hejl  Reagan  Straw  Chase  Wherley  Benjamin  Bowling  Rebecca  McInnes  Kevin 《Precision Agriculture》2022,23(5):1908-1917

Precision irrigation utilizing soil moisture data and valve-in head sprinkler systems may be a viable solution for sustainable water management on complex turfgrass areas. There is currently no research investigating the factors that influence soil moisture and turfgrass quality variability within sand-capped golf course fairways to aid in precision irrigation-related management decisions. Therefore, the objective of this study was to measure several turfgrass and soil characteristics from two sand-capped fairways during dry down events from either rainfall or irrigation to determine their relationship and contribution to soil moisture and turfgrass quality variability. Considerable spatiotemporal variability was observed within the two fairways during the dry down periods. Factors that were found to have a significant influence on soil moisture and turfgrass quality were sand capping depth, elevation, and thatch depth, but these relationships were not consistent between rainfall versus irrigation events, days after dry down, or even the specific fairways. Also, the direction of many of the relationships were opposite of what was expected. These findings highlight the complexity of soil moisture and turfgrass quality variability on sand-capped golf course fairways. To incorporate soil moisture sensor technologies into large-scale precision irrigation practices, mapping soil moisture with an understanding of contributing factors is a necessary preliminary step. Although there are several current practical limitations, the information presented in this study provides a foundation for future research.

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Handling Alternative Dietary Requests from Pet Owners     

Jacqueline M. Parr  Rebecca L. Remillard 《Veterinary Clinics of North America: Small Animal Practice》2014

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Cytotoxic Effects of Loperamide Hydrochloride on Canine Cancer Cells     

Rebecca Cohen REGAN  Robert Michael GOGAL  Jr  James Perry BARBER  Richard Cary TUCKFIELD  Elizabeth Wynne HOWERTH  Jessica Ann LAWRENCE 《The Journal of veterinary medical science / the Japanese Society of Veterinary Science》2014,76(12):1563-1568

Loperamide is a peripheral opiate agonist that can cause apoptosis and G2/M arrest in human cancer cell lines and may sensitize cells to chemotherapy. The objectives of this study were to investigate the effects of loperamide on viability, apoptosis and cell cycle kinetics in canine cancer cells and to establish whether the drug sensitizes cells to doxorubicin. Cell viability was assessed using Alamar Blue. Cell death and cell cycle were studied using flow cytometry with 7-Aminoactinomycin-D (7-AAD) and propidium iodide (PI), respectively. Loperamide decreased cell viability in a dose-dependent fashion and was most effective against canine osteosarcoma cells. In all cell lines, it induced a dose and time dependent apoptosis and resulted in accumulation in G0/G1. When co-incubated with doxorubicin, loperamide induced a synergistic cell kill in canine carcinoma cells. Investigation is warranted into the role of loperamide in the treatment of canine cancer.  相似文献