Nematicidal activity of furanocoumarins from parsley against Meloidogyne spp.          下载免费PDF全文

Pierluigi Caboni  Marco Saba  Chrisostomos Oplos  Nadhem Aissani  Andrea Maxia  Urania Menkissoglu‐Spiroudi  Laura Casu  Nikoletta Ntalli 《Pest management science》2015,71(8):1099-1105

  相似文献   

Young Scientist Award essay winner. Construction of a minimal, protein-free spliceosome     

Valadkhan S 《Science (New York, N.Y.)》2005,307(5711):863-864

  相似文献   

Characterization of a low expression haplotype in canine glutathione S‐transferase (GSTT1) and its prevalence in golden retrievers          下载免费PDF全文

S. Craft  J. Ekena  B. Mayer  D. H. Thamm  C. Saba  R. Chun  L. A. Trepanier 《Veterinary and comparative oncology》2018,16(1):E61-E67

  相似文献   

Mammary gland tumors in male dogs     

Saba CF  Rogers KS  Newman SJ  Mauldin GE  Vail DM 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(5):1056-1059

BACKGROUND: Reports of mammary-gland tumors in male dogs are lacking. OBJECTIVE: To describe the clinical characteristics of mammary-gland tumors in male dogs. ANIMALS: Eight male dogs diagnosed with mammary-gland tumors. METHODS: Retrospective study. Medical databases from 3 institutions were searched. Medical records were abstracted, and owners and referring veterinarians contacted for follow-up information. Tissues were reviewed for histologic type, and immunohistochemical staining for estrogen and progesterone receptors (ER, PR) was performed. RESULTS: Eight dogs with histologically confirmed mammary-gland tumors were included in this retrospective study. Median age at diagnosis was 11.5 years. Four dogs were sexually intact; 4 were neutered. All were purebred. Mammary-gland tumors were incidental findings in 7 of 8 dogs. All dogs were treated with only surgical excision. All but 1 dog had benign epithelial tumors. The dog with the malignant tumor was the only dog to develop possible local recurrence but de novo tumor development cannot be excluded. No dog had evidence of metastatic disease at diagnosis. Based on institutional population data, it was determined that female dogs are 62 times more likely to develop mammary-gland tumors than male dogs (P < .001). Estrogen-receptor expression was strong in the majority of tumors; progesterone-receptor expression, although present in all tumors, was less intense. CONCLUSIONS/CLINICAL IMPORTANCE: This study suggests that mammary-gland tumors in male dogs are rare, usually benign, and surgery alone can provide long-term control in most dogs.  相似文献   

Cooling Bose-Einstein condensates below 500 picokelvin     

Leanhardt AE  Pasquini TA  Saba M  Schirotzek A  Shin Y  Kielpinski D  Pritchard DE  Ketterle W 《Science (New York, N.Y.)》2003,301(5639):1513-1515

Spin-polarized gaseous Bose-Einstein condensates were confined by a combination of gravitational and magnetic forces. The partially condensed atomic vapors were adiabatically decompressed by weakening the gravito-magnetic trap to a mean frequency of 1hertz, then evaporatively reduced in size to 2500 atoms. This lowered the peak condensate density to 5 x 10(10) atoms per cubic centimeter and cooled the entire cloud in all three dimensions to a kinetic temperature of 450 +/- 80 picokelvin. Such spin-polarized, dilute, and ultracold gases are important for spectroscopy, metrology, and atom optics.  相似文献   

Masitinib mesylate does not enhance sensitivity to radiation in three feline injection-site sarcoma cell lines under normal growth conditions     

M. Turek  R. Gogal Jr.  C. Saba  M.L. Vandenplas  J. Hill  B. Feldhausser  J. Lawrence 《Research in veterinary science》2014

Masitinib, a selective tyrosine kinase inhibitor, was investigated as a radiosensitizer in three primary feline injection-site sarcoma (ISS) cell lines. Sensitivity to masitinib was previously assessed via cell growth inhibition assays with mean IC₅₀ values of 5.5–8.6 μM. Clonogenic assays were performed to determine the effect of masitinib and radiation on cell survival. Single dose radiation (0–12 Gy) experiments were carried out under normal growth conditions in control ISS cells and in cells incubated with 1 or 6 μM masitinib for 72 h prior to irradiation. Radiation administered either alone or in combination with masitinib induced a dose-dependent reduction in clonogenic survival. Survival from the combined masitinib and radiation treatment was not significantly different from that of radiation alone. Results suggest that masitinib does not directly enhance ISS cell radiosensitivity under normal in vitro conditions, although this does not preclude the utility of further investigations to assess sensitization properties under altered conditions.  相似文献   

In vitro efficacy of doxorubicin and etoposide against a feline injection site sarcoma cell line     

Joseph Hill  Jessica Lawrence  Corey Saba  Michelle Turek  Brittany Feldhaeusser  Sheryl Coutermarsh-Ott  Jamie Barber  Jo Smith  Robert Gogal Jr 《Research in veterinary science》2014

Feline injection site sarcoma (ISS) is a locally invasive tumor, in which surgical treatment is frequently combined with radiation or chemotherapy to improve tumor control. The focus of this study was to evaluate the cytotoxic effects of doxorubicin or etoposide on a feline injection site sarcoma cell line (JB) and to assess the impact of combining these drugs on cell death and cell cycle. Both single agent and combination drug administration increased cell death and significantly reduced the number of viable cells. Cells in G0/G1 were significantly reduced while the G2/M fraction was significantly increased following treatment. Collectively, combining doxorubicin and etoposide at the lower EC yielded comparable results to the EC50 of either drug alone in degree of cytotoxicity, level of apoptosis, and % of cells in G2/M. The results of this study indicate that doxorubicin and etoposide alone and in combination differentially alter ISS cell viability and cycle.  相似文献   

Identification of 9(E),11(E)-18:2 fatty acid methyl ester at trace level in thermal stressed olive oils by GC coupled to acetonitrile CI-MS and CI-MS/MS, a possible marker for adulteration by addition of deodorized olive oil     

Saba A  Mazzini F  Raffaelli A  Mattei A  Salvadori P 《Journal of agricultural and food chemistry》2005,53(12):4867-4872

The olive oil market is suffering from sophisticated illegal treatments. One common adulteration process consists of the addition to virgin olive oil of lower quality oils, such as "lampante" oil, an inexpensive oil and with some organoleptic defects, which is then submitted to thermal deodorization under vacuum processes for removal of the undesired flavor components. Such a blending may not have a huge influence on the chemical composition and may not significantly affect the parameters usually checked as quality indicators, although the organoleptic properties may change. As a consequence, a major effort is being devoted to find reliable markers able to unmask such adulterations. We report here the complete characterization of a compound, detected at trace levels exclusively in thermal stressed oils, which could be a candidate marker for adulteration. The investigation, carried out by GC-MS and GC-MS/MS, provided its complete structure, including the stereochemistry, shown to be a 9(E),11(E)-18:2 fatty acid methyl ester. Experimental data also confirmed the influence of both temperature and heating time on formation and concentration of this compound.  相似文献   

Comparative Effect of Wastewater and Groundwater Irrigation Along with Nitrogenous Fertilizer on Growth,Photosynthesis and Productivity of Chilli (Capsicum annuum L.)     

Saba Iqbal  Hamid Iqbal Tak  Arif Inam  Akhtar Inam  Seema Sahay  Shaista Chalkoo 《Journal of plant nutrition》2015,38(7):1006-1021

A study was made in the net house of Plant Physiology, Department of Botany, Aligarh Muslim University, Aligarh to study the comparative effect of wastewater and groundwater along with three different rates of nitrogen (N) of 0, 30, and 60 kg ha^?1 on growth, physiology and yield of two varieties of chilli cv. ‘G4’ and ‘Pusa Jawala’. Wastewater irrigation resulted significant increase in shoot and root length, fresh weight, dry weight, leaf number and area, net photosynthetic rate (P_N), stomatal conductance (g_s), water use efficiency (WUE), chlorophyll content, and yield. The physio-chemical parameters of wastewater met the irrigational characteristics, being well within the permissible limit as outlined by the Food and Agriculture Organization. Among the nitrogen doses 30 kg ha^?1 N along with wastewater proved best for the growth and yield. Thus it may be concluded that wastewater reduced the demand of fertilizers and it may be used for the cultivation of chilli.  相似文献   

Consumer perceptions of healthy cereal products and production methods     

M. Dean  R. Shepherd  A. Arvola  M. Vassallo  M. Winkelmann  E. Claupein  L. Lähteenmäki  M.M. Raats  A. Saba 《Journal of Cereal Science》2007

Using a survey, this study investigated public perceptions relating to different healthy grain foods (bread, pasta and biscuits) and how these perceptions are influenced by gender, nationality, base product (staple vs. fun food), type of health claim (general vs. specific) and people's perceptions associated with different production methods. Two thousand and ninety-four (50.4% women, 49.5% men) members of the public from the UK, Italy, Finland and Germany completed the survey questionnaire. The participants were over 18 years of age and were solely or jointly responsible for the family's grocery shopping.  相似文献