人员在岗培训在实施兽药GMP现场管理中的作用     

宋立荣  康孟佼  郑雪花  李晶 《中国兽药杂志》2007,41(9):45-47

论述了对兽药生产企业进行人员在岗培训的必要性,对实施在岗培训的基本程序和应注意的事项进行了总结,旨在为兽药企业进行GMP现场管理提供参考。  相似文献   

Comparative efficacy of crystalline and amorphous oxfendazole in sheep     

MJ CARRIGAN  P PILE  BF CHICK 《Australian veterinary journal》1990,67(5):195-196

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Alterations of wood characteristics in Abies alba Mill. due to “fir–dying” and considerations concerning its origin     

J. Bauch  P. Klein  A. Frühwald  H. Brill 《Forest Pathology》1979,9(6):321-331

In the wood of trees of Abies alba Mill., which were affected by “fir–dying”, morphological and physiological alterations were examined in order to investigate the origin of the disease. In this context also the influence on the technological wood quality was considered.  相似文献   

Symptoms of forest decline (Waldsterben) on Norway and red spruce     

H. Liedeker  P. Schütt  R. M. Klein 《Forest Pathology》1988,18(1):13-25

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Effect of Breeding Activity on the Microflora of the External Genitalia and in the Semen of Stallions,and the Relationship Between Micro‐organisms on the Skin and on the External Genitalia     

T Guimarães  C Miranda  M Pinto  E Silva  L Damásio  AL Costa  MJ Correia  JC Duarte  C Cosinha  G Lopes  G Thompson  A Rocha 《Reproduction in domestic animals》2014,49(6):926-933

A possible role of breeding activities in the composition of the microbial population in stallions' external genitalia (EG) and the relationship between micro‐organisms colonizing the skin of the abdomen and the ones colonizing the EG have not been studied. In experiment 1, EG microbiological samples were collected from 41 stallions used for both natural cover and semen collection (BST) and from 18 non‐breeding stallions (NBST). A higher (p < 0.05) frequency of isolation of potentially pathogenic species was found for BST. Age did not influence number of micro‐organism species isolated both in BST and NBST. In experiment 2, the microbial content of the EG and semen was compared in 23 BST. Most micro‐organisms isolated from the EG were present in semen, albeit with a numerically lower prevalence. In 7 stallions, six microbial species isolated from semen were absent from the EG cultures, suggesting contamination by the operator. In experiment 3, a numerically higher number of micro‐organism species was isolated from the EG of 31 stallions, than from their skin of the ventral abdomen in contact with the penis or from the skin of the thorax. With the sole exception of Escherichia coli, potentially pathogenic bacteria were only isolated from the EG but not from the skin. Results suggest that breeding activity increased the number of species colonizing the EG; most species isolated from the EG were also found in semen even if with a lower frequency, and additional semen contamination seemed to occur during its manipulation. Many micro‐organism species of the skin were also isolated from the penis, but independently of being or not in contact with the penis, skin did not seem to provide an adequate environment for the growth of potentially pathogenic bacteria that were isolated from EG, with the sole exception for E. coli.  相似文献   

Microbiological Quality Assessment of Watershed Associated with Animal-Based Agriculture in Santa Catarina, Brazil     

Gilbert C. Sigua  Julio Cesar Pascale Palhares  Jalusa Deon Kich  Magda Regina Mulinari  Rosemari Martini Mattei  Jaqueline Bianca Klein  Susana Muller  Gustavo Plieske 《Water, air, and soil pollution》2010,210(1-4):307-316

Environmental problems many times could evolve when manure-containing pathogens are distributed into an open environment with no effort made to reduce the content of pathogens or limit their movement in the environment. Wind, surface flow, and subsurface flow can all carry enough pathogens to receiving waters to exceed water quality standards. This study was conducted to assess the microbiological quality of water associated with animal-based agriculture in the sub-basin of Pinhal River located in the rural area of Concordia, Santa Catarina, Brazil. Six sampling points representing different agricultural land uses (LU1—dairy cattle; LU2—without animals; LU3—dairy + pigs + poultry + crops; LU4—pigs + poultry + crops; LU5—dairy + pigs + poultry + crops + human; and LU6—dairy+pigs+crops) along the Pinhal River sub-basin (north to south) were sampled biweekly from August 2006 to December 2008. Concentrations of fecal coliforms and Escherichia coli varied significantly (p?≤?0.05) with land use (LU), but there was no interaction effect of LU, season, and time. Water samples from the catchment area of LU1 had the highest concentration of fecal coliforms (4,479?±?597 CFU ml^?1) when compared with other catchment areas. Catchment area associated with LU2 (no animal) had the lowest concentrations of fecal coliforms (39.2?±?5.2 CFU ml^?1). With the exception of LU2 (control site), all the maximum concentrations of E. coli exceeded the single maximum allowable concentration for E. coli (100 CFU ml^?1). When LU1 was compared with other catchment areas (LU3, 50%; LU4, 67%; LU5, 58%; and LU6, 44%), it had the lowest counts (39%) of Salmonella sp. Our results suggest that spatial pattern of bacterial water quality is evident, which can be linked to the different land uses and associated practices (present or absent of animal activities). Therefore, varying responses associated with the different land uses would be critical in identifying the importance of different sources of bacteria in the catchment area and the mechanisms transferring them.  相似文献   

Effect of the nutrition level and sex on the energy maintenance requirement of broilers and rats     

M Klein  L Hoffmann  R Schiemann 《Archives of Animal Nutrition》1990,40(9):773-791

In 3 experiments young broiler chickens were supplied on various feeding levels in the growth range between 200 and 2500 g live weight (2.8 and 2.0 in experiment 1, 2.8, 2.3 and 1.8 in experiments 2 and 4, maintenance = feeding level 1.0). In experiments 1 and 2 short-time measurings (30 min) of heat production by means of gas exchange were made at 500, 1000, 1500 and 2000 g live weight in the post-absorptive state and on the maintenance level of feeding. In experiment 1 the heat production of the restrictively fed chickens was in 3 out of the 4 stages of development studied significantly lower by 10-14% than that of the intensively fed ones. In experiment 2 such an effect could not be observed. Fed on the level of energy maintenance, broilers weighing approximately 2000 g (experiment 3) did not show a significant influence of the sex on heat production as a result of 30-minute gas exchange measurings in the post-absorptive state. In experiment 4 24-hour measurings of the energy metabolism were carried out in the growth development in periods of feeding on the maintenance level by means of indirect calorimetry. In the live weight range between 0.9 and 1.3 kg there was only a low, non-significant decrease of the energy maintenance requirement of 4-6% of the highly restrictively fed chickens in comparison to the intensively fed ones. After continued feed restriction (live weight range 1.7-2.2 kg) an energy maintenance requirement reduced by 17% was measured. In an analogously arranged experiment with 24-hour energy metabolism measurings (experiment 5) male Wistar rats in the growth range between 70 and 280 g were supplied on the feeding levels 1.8 and 1.4 resp. In all three periods studied on the feeding level maintenance--beginning at 140-150 g live weight--the highly restrictively fed animals showed a slightly reduced energy maintenance requirement by 8%, 3% (non-significant) and 6% in comparison with the intensively fed animals.  相似文献   

Poxviruses: then and now     

MJ STUDDERT 《Australian veterinary journal》1991,68(5):180-181

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Toxigenic type D Pasteurella multocida and progressive atrophic rhinitis in New South Wales pig herds     

IA GARDNER  GJ EAMENS  MJ TURNER  CL HORNITZKY 《Australian veterinary journal》1991,68(11):364-365

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Diagnosis of equine herpesvirus 1 abortion using polymerase chain reaction     

JT MACKIE  GA MACLEOD  GH REUBEL  MJ STUDDERT 《Australian veterinary journal》1996,74(5):390-391

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