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41.
冰草提取物对桃蚜的杀虫活性及对体内两种酶活性的影响 总被引:5,自引:0,他引:5
重点介绍了冰草的不同溶剂提取物对桃蚜的杀虫活性及其对蚜虫体内蛋白酶、谷胱甘肽-S-转移酶活性的影响。结果表明,冰草氯仿和水提取物对桃蚜有较好的内吸活性,并对桃蚜体内蛋白酶、谷胱甘肽-S-转移酶活性均有明显抑制作用,而在触杀处理中,提取物对蚜虫各酶系活性的影响不明显。 相似文献
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《农业科学与技术》2013,(10):1403-1408
Advanced glycation end-products (AGEs) are products of non-enzymatic glycation of proteins, lipids or nucleic acids and other macromolecules. To be spe- cific, Nε-(carboxymethyl)-Iysine (CML) is one of the most important components of AGEs, which is wildly distributed in the body and can be formed in vivo or in food processing and heating processes. Previous studies have shown that CML is a ma- jor immunological epitope in AGEs and plays an important role in diabetes and its complications, as well as in the development and progression of aging. This review summarized recent advances in major source, toxicological hazard and control mea- sures of CML. 相似文献
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The in vivo metabolism of [14CH3S]- and [14CH3O]O,O,S-trimethyl phosphorothioate (OOS) was followed in rats after oral administration of threshold or LD50 toxic doses of 20 or 60 mg/kg. Similar metabolic studies were conducted with coadministration of 1% O,O,O-trimethyl phosphorothionate (OOO), which prevented all signs of delayed toxicity, including weight loss. When administered alone, OOS was metabolized mainly (50–60%) via removal of the CH3S moiety, which was largely converted to expired CO2. Approximately 20% of the compound was O-demethylated, presumably by conjugation with glutathione, and then further metabolized to CO2. Major urinary products were identified as O,O-dimethyl phosphoric acid (50–60%) and O,S-dimethyl phosphorothioic acid (~20%). Coadministration of OOO caused a slight decrease (~5%) in the cleavage of the CH3S moiety, indicated by a reduction in 14CO2 from [14CH3S]OOS and a quantitatively similar increase in the formation of O,S-dimethyl phosphoric acid. Limited pharmacokinetic studies indicated that OOS was rapidly absorbed and distributed throughout the body. Coadministration of 1% OOO caused a slight increase in the blood half-life of parent OOS when administered at 60 mg/kg. It was concluded that a small proportion of the cleavage of the CH3S moiety from OOS is involved in the intoxication process, and that this intoxication reaction is specifically inhibited by OOO. 相似文献
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为研究由淫羊藿、黄芪、菟丝子、牡蛎等中药配伍而成的复方中药的药效和毒性,评价其在畜牧业生产中的有效性、安全性,试验对海兰褐蛋鸡进行给药研究。选取44周龄的母鸡210只,随机分成7组,每组30只,设3个重复,每个重复10只,复方Ⅰ(A_1、B_1、C_1),复方Ⅱ(A_2、B_2、C_2),空白对照组D,试验时间为49 d,每天的下午16:00给试验动物投喂伴有受试药物的饲粮。每天的同一时间(16:00)捡蛋1次,每周对鸡蛋称重,每周称取余料量1次,记录产蛋率、料蛋比、破壳、软壳率等生产性能指标,用蛋白高度分析仪、蛋壳测定仪测定蛋壳强度、哈氏单位等蛋品质指标。结果表明:复方Ⅱ能显著提高产蛋率、降低料蛋比、降低日采食量、提高蛋壳强度(P<0.05),故将该口服液命名为益阳增蛋口服液,该口服液能显著提高母鸡产蛋性能。 相似文献
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