排序方式： 共有11条查询结果，搜索用时 31 毫秒
1.
Amin A. Nomeir Nicolas P. Hajjar Ernest Hodgson Walter C. Dauterman 《Pesticide biochemistry and physiology》1980,13(2):112-120
EPN is twice as toxic as EPNO to house flies from both the Diazinon-resistant strain and the susceptible strain. EPN and EPNO are also eight times more toxic to the susceptible than the resistant strain. This is due to the ability of the resistant strain to metabolize these compounds to a greater extent. Metabolism by the glutathione S-transferases present in the 100,000g supernatant is more extensive than that by the NADPH-dependent microsomal mixed-function oxidases. The glutathione S-transferases are the major route of metabolism for EPN and appear to be the principal mechanism conferring resistance. EPN was metabolized by the microsomal fraction via oxidative desulfuration to the oxygen analog, EPNO, and by oxidative dearylation to p-nitrophenol. EPNO was metabolized by the same system to p-nitrophenol and desethyl EPNO as well as to an unknown metabolite. The soluble fraction metabolized EPN to p-nitrophenol, S-(p-nitrophenyl)glutathione, O-ethyl phenylphosphonothioic acid, and S-(O-ethyl phenylphosphonothionyl)glutathione. The identification of the latter conjugate demonstrates a new type of metabolite of organophosphorus compounds. EPNO was metabolized by the soluble fraction to p-nitrophenol and S-(p-nitrophenyl)glutathione. 相似文献
2.
Desneux Nicolas Han Peng Mansour Ramzi Arn&#; Judit Br&#;vault Thierry Campos Mateus R. Chailleux Anais Guedes Raul N. C. Karimi Javad Konan Kouassi Arthur J. Lavoir Anne-violette Luna Mar&#;a G. Perez-Hedo Meritxell Urbaneja Alberto Verheggen Fran&#;ois J. Zappal&#; Lucia Abbes Khaled Ali Abid Bayram Yunus Cantor Fernando Cuthbertson Andrew G. S. De Vis Raf Erler Fedai Firake Dnyaneshwar M. Haddi Khalid Hajjar M. Jamal Ismoilov Khasan Jaworski Coline C. Kenis Marc Liu Hao-tian Madadi Hossein Martin Thibaud Mazih Ahmed J. Messelink Gerben Mohamed Samira A. Nofemela Robert S. Oke Abiola Ramos C&#;sar Ricupero Michele Roditakis Emmanouil Shashank Pathour R. Wan Fang-Hao Wang Ming-hui Wang Su Zhang Yi-Bo Biondi Antonio 《Journal of pest science》2022,95(1):17-39
Journal of Pest Science - The South American tomato pinworm, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae), has invaded most Afro-Eurasian countries and is threatening worldwide tomato... 相似文献
3.
Structurally homologous ligand binding of integrin Mac-1 and viral glycoprotein C receptors 总被引：3，自引：0，他引：3
D C Altieri O R Etingin D S Fair T K Brunck J E Geltosky D P Hajjar T S Edgington 《Science (New York, N.Y.)》1991,254(5035):1200-1202
Three spatially distant surface loops were found to mediate the interaction of the coagulation protein factor X with the leukocyte integrin Mac-1. This interacting region, which by computational modeling defines a three-dimensional macromotif in the catalytic domain, was also recognized by glycoprotein C (gC), a factor X receptor expressed on herpes simplex virus (HSV)-infected endothelial cells. Peptidyl mimicry of each loop inhibited factor X binding to Mac-1 and gC, blocked monocyte generation of thrombin, and prevented monocyte adhesion to HSV-infected endothelium. These data link the ligand recognition of Mac-1 to established mechanisms of receptor-mediated vascular injury. 相似文献
4.
The 1-benzoyl-3-phenylurea insecticide diflubenzuron is a potent inhibitor for the conversion of (14)C-labeled glucose to (14)C-labeled chitin in isolated abdomens of newly emerged adult milkweed bugs (Oncopeltus fasciatus Dallas). The inhibitory activity of 24 diflubenzuron analogs in this in vitro chitin-synthesizing system is in good agreement with their toxicity to fifth instar nymphs of this species. These insecticides act quickly and directly within the integument to ultimately block the terminal polymerization step in chitin formation. 相似文献
5.
Fouad Maalouf Shaaban KhalilSeid Ahmed Akinnola N. AkintundeMohammed Kharrat Khaled El Shama’aSamir Hajjar Rajinder S. Malhotra 《Field Crops Research》2011,124(3):288-294
Faba bean (Vicia faba L.) is one of the important pulse crops grown in many parts of the world. Its production and productivity are affected by different biotic and abiotic stresses. Broomrape (Orobanche and Phelipanche spp.) causes yield losses of 7- 80% in major faba bean growing countries mainly in the Mediterranean Basin and Nile Valley countries. Host plant resistance is found to be the most effective and economic method of broomrape control. Efforts made at the International Center for Agriculture Research in the Dry Areas over many years to develop advanced breeding lines with acceptable resistance and tolerance levels to broomrape have resulted in the identification of several useful breeding lines. These lines were shared with National Agricultural Research Systems (Egypt, Sudan, Tunisia and Portugal) as part of the Faba Bean Orobanche International Nursery, in order to test their stability across three seasons (2005, 2006 and 2007). The results showed that Orobanche plant number, dry weight, Orobanche index, flowering date, maturing date and grain yield were significantly different among lines and locations. AMMI analysis showed that some lines derived from hybrid bulk populations “HBP/DS0/2000” and “HBP/ES0/2000” showed acceptable levels of yield stability in the presence of Orobanche infections across all environments compared with susceptible check. In highly infested soils, the tolerant and resistant lines gave acceptable levels of yield compared with the susceptible check. However, the yield potential of resistant and tolerant lines in non-infested soils was lower than the highly susceptible check. 相似文献
6.
The use of wild relatives in crop improvement: a survey of developments over the last 20 years 总被引：7，自引：3，他引：7
Hypersensitive, race specific genes primarily have been deployed to control powdery mildew (Blumeria graminis (DC) EO Speer f. sp. tritici) in wheat (Triticum aestivum L.); however, recent efforts have shifted to breeding for more durable resistance. Previously, three quantitative trait loci
(QTL) for adult plant resistance (APR) to powdery mildew in the winter wheat cultivar Massey were identified in a Becker/Massey
(BM) F
2:3 population. Fourteen new simple sequence repeat (SSR) markers were added to the pre-existing BM F
2:3 linkage maps near the QTL for APR on chromosomes 1BL (QPm.vt-1BL), 2AL (QPm.vt-2AL), and 2BL (QPm.vt-2BL). Genetic linkage maps comprised of 17 previously and newly mapped SSRs from the BM population on chromosomes 1BL, 2AL, and
2BL were constructed in a USG 3209/Jaypee (UJ) F
6:7 recombinant inbred line (RIL) confirmation population, wherein the APR resistance of USG 3209 was derived from Massey. Interval
mapping analysis of mildew severity data collected in 2002 (F
5:6) and 2003 (F
6:7) field experiments with marker genotypic data obtained in 2003 (F
6:7) confirmed the presence of the three QTL governing APR to powdery mildew in the UJ RILs. The QTL QPm.vt-1BL, QPm.vt-2AL, and QPm.vt-2BL explained 12–13, 59–69, and 22–48% of the phenotypic variance for powdery mildew severity in the UJ confirmation populations,
respectively, in two field experiments. The current study verified that the elite wheat cultivar USG 3209 possesses the same
QTL for APR as its parent Massey. 相似文献
7.
Al Rawi S Louvet-Vallée S Djeddi A Sachse M Culetto E Hajjar C Boyd L Legouis R Galy V 《Science (New York, N.Y.)》2011,334(6059):1144-1147
In sexual reproduction of most animals, the spermatozoon provides DNA and centrioles, together with some cytoplasm and organelles, to the oocyte that is being fertilized. Paternal mitochondria and their genomes are generally eliminated in the embryo by an unknown degradation mechanism. We show that, upon fertilization, a Caenorhabditis elegans spermatozoon triggers the recruitment of autophagosomes within minutes and subsequent paternal mitochondria degradation. Whereas the nematode-specific sperm membranous organelles are ubiquitinated before autophagosome formation, the mitochondria are not. The degradation of both paternal structures and mitochondrial DNA requires an LC3-dependent autophagy. Analysis of fertilized mouse embryos shows the localization of autophagy markers, which suggests that this autophagy event is evolutionarily conserved to prevent both the transmission of paternal mitochondrial DNA to the offspring and the establishment of heteroplasmy. 相似文献
8.
Fibroblast growth factor receptor is a portal of cellular entry for herpes simplex virus type 1 总被引：16，自引：0，他引：16
R J Kaner A Baird A Mansukhani C Basilico B D Summers R Z Florkiewicz D P Hajjar 《Science (New York, N.Y.)》1990,248(4961):1410-1413
Herpes simplex virus type 1 (HSV-1) is a ubiquitous pathogen responsible for considerable morbidity in the general population. The results presented herein establish the basic fibroblast growth factor (FGF) receptor as a means of entry of HSV-1 into vertebrate cells. Inhibitors of basic FGF binding to its receptor and competitive polypeptide antagonists of basic FGF prevented HSV-1 uptake. Chinese hamster ovary (CHO) cells that do not express FGF receptors are resistant to HSV-1 entry; however, HSV-1 uptake is dramatically increased in CHO cells transfected with a complementary DNA encoding a basic FGF receptor. The distribution of this integral membrane protein in vivo may explain the tissue and cell tropism of HSV-1. 相似文献
9.
Kaner RJ Baird A Florklewicz RZ Mansukhani A Basilico C Hajjar DP 《Science (New York, N.Y.)》1991,253(5016):209-210
10.
Community-based Forest Operations (CFOs) have played a notable role in promoting sustainability within Cameroon??s indigenous forest-dependent communities, but they are fraught with a range of socio-economic and ecological hurdles. As a means of achieving more sustainable forest practices, one possible solution would be for CFOs to adopt forest certification, though various barriers would have to be overcome. Using a number of examples at the regional level, this paper examines the potential benefits and barriers to community forest certification in Cameroon. Specifically, the paper identifies these barriers as legislative and political, economic, and informational in nature. While adoption of forest certification hinges upon what initiatives are employed by CFOs, it is argued that there is also a need for the government of Cameroon to play a leadership role in removing hurdles and promoting the uptake of certification. 相似文献