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1.
铬在增强畜禽抗应激与免疫机能中的作用 总被引:3,自引:0,他引:3
铬是动物所必需的一种微量元素,在动物体内碳水化合物,蛋白质,脂肪的代谢起重要作用。近年来研究发现铬的抗应激和提高免疫机能上有特殊的作用。本文就这一热点问题进行综述。 相似文献
2.
Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs 总被引:9,自引:0,他引:9
K. KÜNG J.-L. RIOND M. WANNER 《Journal of veterinary pharmacology and therapeutics》1993,16(4):462-468
Rung, K., Riond, J.-L. & Wanner, M. Pharmacokinetics of enrofloxacin and its metabolite ciprofloxacin after intravenous and oral administration of enrofloxacin in dogs. J. vet
Four dogs were given 5 mg/kg body weight enrofloxacin intravenously (i.v.) and orally (p.o.) in a cross-over study. Plasma concentrations of the active ingredient enrofloxacin and its main metabolite ciprofloxacin were determined by a reversed phase liquid chromatographic method. Pharmacokinetic parameters of both substances were calculated by use of statistical moments and were compared to those of enrofloxacin described in the veterinary literature. Mean enrofloxacin t½λZ was 2.4 h, mean Cls was 27.1 ml/min-kg, and mean Vss was 7.0 1/kg. After i.v. and p.o. administration, concentrations of ciprofloxacin exceeding minimal inhibitory concentrations of several microorganisms were reached (Cmax = 0.2 ng/ml, max = 2.2 h after intravenous administration; Cmax = 0.2 (ig/ml, t max = 3.6 h after oral administration). A considerable part of the antimicrobial activity is due to ciprofloxacin, the main metabolite of enrofloxacin. 相似文献
Four dogs were given 5 mg/kg body weight enrofloxacin intravenously (i.v.) and orally (p.o.) in a cross-over study. Plasma concentrations of the active ingredient enrofloxacin and its main metabolite ciprofloxacin were determined by a reversed phase liquid chromatographic method. Pharmacokinetic parameters of both substances were calculated by use of statistical moments and were compared to those of enrofloxacin described in the veterinary literature. Mean enrofloxacin t
3.
P.C. MILLS J.C. NG A.A. SEAWRIGHT D.E. AUER† 《Journal of veterinary pharmacology and therapeutics》1995,18(3):204-209
Vascular leakage induced by intradermal injection of endotoxin, zymosan-activated plasma (ZAP) and platelet-activating factor (PAF) was measured in nine Thoroughbreds using 125-iodine human serum albumin (125 I-HSA) as a marker in the blood. ZAP and PAF produced dose-dependent increases in vascular permeability with the maximum occurring within the first 15 min after injection. The vascular leakage induced by endotoxin was also dose-dependent, but the maximum occurred 2 h after intradermal injection. Intradermal sites previously injected with endotoxin were refractory to a second injection of endotoxin for up to 5 days. However, sites injected with endotoxin and re-injected with either ZAP or PAF remained responsive with increased vascular leakage compared to saline injected control sites re-injected with either ZAP or PAF. Diminished response to endotoxin challenge may contribute to the poor prognosis of endotoxaemia in the horse. 相似文献
4.
5.
Kaldrymidou E Papaioannou N Poutahidis T Karayannopoulou M Gruys E Toliou T Tsangaris T 《Journal of veterinary medicine. A, Physiology, pathology, clinical medicine》2000,47(8):457-462
A case of a canine large cell type T-cell lymphoma, with features of high-grade malignancy is described. The tumour was found confined in the nasal cavity and the paranasal sinuses of a crossbred German Shepherd dog. Histological examination revealed the features of a highly malignant large cell lymphoma. Ultrastructurally, the lymphoid tumour cells bore cytoplasmic protrusions that interdigitated tightly. From a panel of tumour markers used, the neoplastic cells were stained only for vimentin. Immunophenotyping of the tumour cells by means of CD3, CD79, kappa-light chains and lambda-light chains detection was undertaken. The tumour stained only for CD3 and was classified as T-cell lymphoma. 相似文献
6.
D. E. AUER J. C. NG A. A. SEAWRIGHT 《Journal of veterinary pharmacology and therapeutics》1990,13(1):67-75
Topically applied copper phenylbutazone, phenylbutazone, copper salicylate, salicylate and dimethylsulfoxide glycerol (80:20) were investigated as anti-inflammatory agents in rats and horses. Dimethylsulfoxide and glycerol (80:20) or dimethylsulfoxide, ethanol and glycerol (60:20:20) were used as the drug solvents. Subcutaneously administered carrageenin was used to induce inflammatory oedema, either in the paws of rats or the alar fold of the horse. The severity of the oedema and the anti-inflammatory effect of the drugs were assessed by measuring changes in the paw or alar-fold diameters. Copper salicylate and copper phenylbutazone were effective inhibitors of the inflammatory oedema in both species, but dimethylsulfoxide:glycerol (80:20) was not. In the rat, copper salicylate and copper phenylbutazone were superior anti-inflammatory agents compared to either salicylate or phenylbutazone, respectively. Following the topical application of four times the recommended daily dose of copper phenylbutazone to the horse for 5 days, minor skin irritation occurred and trace concentrations of phenylbutazone (maximum 0.6 microgram/ml) and negligible concentrations of oxyphenbutazone and gamma-hydroxyphenylbutazone were detected in the plasma. 相似文献
7.
海南昌江县燕窝岭石灰岩山体的主要植被型为热带半落叶季雨林.初步调查中发现了两种珍稀濒危植物,它们分别是海南椴(Hainania trichrosperma)与莲桂(Dehaasia hainanensis).当地虽然仍然保留低地树林,但常被利用作采集柴薪与放牧.燕窝岭的岩洞也有被利用作采集燕窝与鸟粪.对燕窝岭自然资源构成最大威胁的是石灰岩开采.本文并对燕窝岭的自然保育与可持续利用提出了建议. 相似文献
8.
Stergios Gakis Konstantinos Mantzanas Dimitrios Alifragis Vasilios P. Papanastasis Athanasios Papaioannou Dimosthenis Seilopoulos Panagiotis Platis 《Agroforestry Systems》2004,60(2):149-157
The interaction between understorey plants and trees in a young silvopastoral system was studied in a sub-humid Mediterranean
environment with cold winters in northern Greece. The experimental design was a split-split plot with three replications and
included: three understorey treatments (grass, legume and control), two tree species (Acer pseudoplatanus and Pinus sylvestris) and two spacings (2.5×2.5 m and 3.5×3.5 m). The competition between herbaceous plants and trees resulted in significant
differentiation in tree growth while their spacing did not produce any significant differences. The influence of trees on
herbage yield either by plant species or spacing was not significant. During the early stages of establishment, a significant
positive correlation was observed between sycamore growth and soil moisture, leaf weight, leaf area and leaf number as well
as nitrogen and potassium concentration in leaves. Six years after planting the height increase of the sycamore trees was
largest in the control treatment (415%), lowest in the grass treatment (134%) and intermediate (192%) in the legume treatment.
Much higher was the increase obtained for the diameter, 161%, 207% and 536% respectively for the grass, legume and control
treatments. The Scots pine trees grew faster than sycamore over the course of the experiment. Height increased by 397%, 351%
and 400% and diameter by 518%, 443% and 683% respectively for the grass, legume and control treatments.
This revised version was published online in June 2006 with corrections to the Cover Date. 相似文献
9.
10.
Depletion of CD4+ T cells in major histocompatibility complex class II-deficient mice 总被引:32,自引:0,他引:32
M J Grusby R S Johnson V E Papaioannou L H Glimcher 《Science (New York, N.Y.)》1991,253(5026):1417-1420
The maturation of T cells in the thymus is dependent on the expression of major histocompatibility complex (MHC) molecules. By disruption of the MHC class II Ab beta gene in embryonic stem cells, mice were generated that lack cell surface expression of class II molecules. These MHC class II-deficient mice were depleted of mature CD4+ T cells and were deficient in cell-mediated immune responses. These results provide genetic evidence that class II molecules are required for the maturation and function of mature CD4+ T cells. 相似文献