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1.
Samira Daniali Arezo Nahavandi Zahra Madjd Ali Shahbazi Somayeh Niknazar Delavar Shahbazzadeh 《Iranian Biomedical Journal》2013,17(3):134-139
Background: Ritalin has high tendency to be abused. It has been the main indication to control attention deficit hyperactivity disorder. The college students may seek for it to improve their memory, decrease the need for sleep (especially during exams), which at least partially, can be related to serotonergic system. Therefore, it seems worthy to evaluate the effect of Ritalin intake on mature brain. There are many studies on Ritalin effect on developing brain, but only few studies on adults are available. This study was undertaken to find Ritalin effect on serotonin transporter (SERT) density in medial frontal cortex (MFC) of mature rat. Methods: Thirty male Wistar rats were used in the study. Rats were assigned into five groups (n = 6 per group): one control, two Ritalin and two vehicle groups. Twelve rats received Ritalin (20 mg/kg/twice a day) orally for eleven continuous days. After one week of withdrawal and another two weeks of rest, in order to evaluate short-term effects of Ritalin, six rats were sacrificed. Another six rats were studied to detect the long-term effects of Ritalin; therefore, they were sacrificed 12 weeks after the previous group. The immunohistochemistry was performed to evaluate the results. Results: Immunohistochemistry studies showed a higher density of SERT in both 2 and 12 weeks after withdrawal from Ritalin intake in MFC of rat and there was no significant difference between these two groups. Conclusions: Our findings demonstrated both short- and long-term effects of Ritalin on frontal serotonergic system after withdrawal period.Key Words: Ritalin, Serotonin, Rats 相似文献
2.
Somayeh Soheili-Movahhed Parisa Sheikhzadeh Bahram Alizadeh 《Journal of plant nutrition》2019,42(8):942-953
Seed yield and quality are affected by water stress occurring at the reproductive stage of crops. Foliar application of micronutrients has been introduced as an agronomic approach to cope with such conditions. This study was undertaken to evaluate the effects of born (B) and zinc (Zn) on seed quantity and quality of spring safflower under late season water deficit. The experimental design was a split factorial in an randomized complete block (RCB) with three replications. The results showed that water deficit during flowering and seed-filling significantly decreased almost all traits compared to control only in 2014. Averaged over the 2 years, seedling length and vigor index were increased by Zn in all irrigation regimes. Germination rate and seed weight were increased by B and Zn in all irrigation treatments. It was concluded that foliar application of 350?ppm B and 1000?ppm Zn can considerably enhance seed yield and quality of safflower grown under terminal drought. 相似文献
3.
Parizad Parisa Abbasi Capraro Jessica Scarafoni Alessio Bonomi Francesco Blandino Massimo Marengo Mauro Giordano Debora Carpen Aristodemo Iametti Stefania 《Plant foods for human nutrition (Dordrecht, Netherlands)》2019,74(1):128-134
This study was aimed at characterizing the anthocyanins and phenolics profile in different varieties of pigmented corn and wheat and in some of their milling fractions. Acid/ethanol extracts were used to assess total anthocyanins, overall antioxidant activity, the overall polyphenol profile, and for evaluating the inhibition of pancreatic α-amylase and of intestinal α-glucosidase. Both enzymes were inhibited in a dose-dependent manner by all extracts, but individual extracts had specific effects on each enzyme. Anti-inflammatory response was evaluated by using acid-free extracts and Caco-2 cells transiently transfected with a luciferase reporter gene responding to cytokine stimulation. The immune response of interleukin-stimulated cells decreased significantly in a dose-dependent manner in the presence of 20–50 μM/l anthocyanins from all grains extracts, again with a different efficiency. The inhibitory ability and the anti-inflammatory capability of these extracts are in most cases higher than in similar extracts from other sources, suggesting that activities in each extract may imply specific synergies between anthocyanins and other phenolics.
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5.
Ali Akbar Ghotbi-Ravandi Maryam Shahbazi Mohammad Pessarakli 《Journal of plant nutrition》2016,39(8):1174-1185
To study the effects of progressive drought stress on photosystem II behavior of wild type (Spantaneum) and cultivated barley (Morocco), different levels of soil water availability, including control, moderate, mild, and severe water stress (70%, 50%, 30%, and 10% water holding capacity of soil, respectively) and rehydration were used. Polyphasic OJIP fluorescence transient of Morocco plants exhibited a considerable increase in fluorescence intensity at O, J, and I steps under mild and severe stress relative to slight increase in wild barley. Values of fluorescence parameters and quantum efficiencies, including minimal fluorescence, relative variable fluorescence at phase J and I, maximal quantum yield of photosystem II (PSII), performance index, electron transport yield, and excitation transfer efficiency were influenced by water stress in both genotypes. These parameters were significantly less affected in wild type barley by progressive drought stress compared to Morocco. After re-watering, both genotypes were able to restore from severe drought in most of the traits. Based on our findings, highly correlated values of relative water content (RWC) and independent JIP-test parameters (P < 0.01) indicate that the chlorophyll a fluorescence induction technique is sensitive to plant water status and performance index represent an accurate and reliable indicator for early stress detection and also explore plant vitality under water stress. 相似文献
6.
Parisa Maleki Saeed Saadat Forood Sharifi Farhad Dehghany Masomeh Salehi 《Communications in Soil Science and Plant Analysis》2018,49(15):1815-1825
Salinity is one of the major agricultural problems in arid and ?semi-arid regions. Considering the variation of plant’s ?sensitivity to salinity during growth, a greenhouse study with completely randomized design? was conducted to determine the relative salinity tolerance of Quinoa (Chenopodium quinoa Willd.) at different growth stages from seedling establishment to maturity (establishment, flowering and seed filling) by evaluating the Salinity Threshold Value (STV). Eight levels of ECi (i.e., Non-saline, 2, 4, 8, 12, 15, 20, 25 dSm?1) with four replications and five levels (i.e., Non-saline, 10, 15, 20, 25 dSm?1) with three triplications were applied at first and two last growth stages, respectively. A ?comparison was performed on some growth and yield parameters of plants irrigated by considering STV (T) and ?plants irrigated permanently by mentioned salinity levels regardless of STV (P) to choose ?which method (P or T) is better at each salinity level. The STV was ?evaluated 8, 20 and 15 dSm?1 at each growth stage, respectively. Seedling of Quinoa was more sensitive to salinity than the mature plant. Therefore, after establishment Quinoa has the ?feasibility of irrigation by high-saline waters. The (P) ?method was suitable only if the freshwater was available during all growth period of the plant; otherwise at higher salinities irrigation should be performed by considering STV (T method) to minimize the intensity of growth and yield reduction and to prevent yield loss at very high salinities. To achieve this, if high-saline water is available it’s possible to ?use plant propagation techniques or cultivating Quinoa simultaneously with seasonal rainfall.? 相似文献
7.
Journal of Plant Diseases and Protection - Black spot disease is the most common diseases of landscape roses and is caused by Diplocarpon rosae Wolf. In Rosa multiflora, the screening of black... 相似文献
8.
Parisa Koobaz Ghasem Hosseini Salekdeh Foad Moradi Hossein Hadavand 《Journal of plant nutrition》2017,40(4):574-583
Four-day-old seedlings of spring wheat (Triticum aestivum L. cv. Marvdasht) can tolerate severe dehydration and recover after re-watering. In order to clarify tolerance mechanism, in a completely randomized design, the seedlings were exposed to drought by complete water cessation for 10 and 20 days, followed by re-watering for 3 and 7 days. Upon dehydration, the activity of α-amylase increased whereas growth parameters; photosynthetic pigments; and the activities of lipoxygenase, indole acetic acid (IAA) oxidase, and ascorbate peroxidase (APX) decreased. The activity of APX and the expression of its gene, however, increased after re-watering. Prolonged dehydration was also accompanied by increase in sucrose, soluble proteins, fructans, and certain amino acids, e.g. proline, glutamine, and valine. The results indicated that during dehydration, 4-day-old wheat seedlings shifted their energy expenditure from basal metabolism to withstand water deficiency via lowering the activity of membrane-damaging enzymes and enhancing the production of osmoprotectants. 相似文献
9.
As global mercury emissions from coal fire power plants increase with the continuing rise of coal consumption, mercury capture methods are being developed to prevent mercury??s escape into the atmosphere. Titanium dioxide (TiO2) in the presence of ultra violet light (UV-A; ?? max ??360?nm) and oxygen will capture mercury as the solid product HgO(s). Testing the effects of TiO2 in the presence of other pollutants has so far been limited. We have performed kinetic and product studies of mercury adsorption in the presence of the gaseous flue co-pollutant NO2(g). We extensively studied the gas-phase reaction of NO2(g) with Hg (g) 0 . We compared the gas-phase reaction to the same reaction performed in the presence of thin TiO2 particle surfaces from 0 to 100?% relative humidity. The second-order rate constant was measured to be k?=?(3.5?±?0.5)?×?10?35?cm6 molecules?2?s?1, independent of the presence of titania or the total surface area available for adsorption. Exposure of NO2(g) to titania surfaces that were already saturated in captured mercury (HgO(s)) increased total mercury uptake onto the surface. We discuss the implications of this study to the capture of mercury emissions prior to release to the atmosphere. 相似文献
10.
Sara Sadat Aghabozorg Afjeh Behzad Boshehri Safar Hamednia Asmaolhosna Asmaolhosna Parisa Mashayekhi Mir Davood Omrani 《Iranian Biomedical Journal》2021,25(3):220
Background:Methadone therapy is a major protocol in opioid addiction cases in many health care systems. Population-based studies have shown that in addicted people, the genetic profile affects their response to methadone therapy. Therefore, this study designed to examine the frequency of two SNPs of the CYP2B6 gene (rs3745274 and rs3211371) in addicted cases in two methadone-responders and methadone non-responders groups. Methods:A total of 199 opioid-addicted individuals and 117 unaffected control subjects were genotyped for rs3745274 and rs3211371 polymorphisms of the CYP2B6 gene using the tetra-primer ARMS-PCR. Results:Results of this study revealed the significant association of rs3745274 GG (p < 0.001; OR = 0.027; 95% CI = 0.14-0.49) and GT (p < 0.001; OR = 4.04; 95% CI = 2.26-7.21) genotypes with the risk of addiction in methadone-responders. Also, a significant association between rs3745274 GG (p < 0.001; OR = 0.28; 95% CI = 0.15-0.51) and GT (p < 0.001; OR = 5.1; 95% CI = 2.8-5.28) genotypes and addiction relapse was found in methadone non-responders. Conclusion:Based on our findings, we can conclude that rs3745274 variant of CYP2B6 gene could serve as a potential biomarker, to evaluate the prognosis of addicted people fate under treatment with methadone. Key Words: Addiction, Biomarker, Methadone, Single-nucleotide polymorphism 相似文献