Serum magnesium levels of ewes grazing orchardgrass topdressed with dolomite of calcite.     

R L Amos  G J Crissman  R F Keefer  D J Horvath 《Journal of animal science》1975,41(1):198-202

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Effects of the plant alkaloid thaliblastine on non-cross-resistant and sensitive human leukemia cells in relation with reversal of acquired anthracycline resistance     

Horvath LE  Konstantinov SM  Ilarionova MV  Todorov DK 《Fitoterapia》2004,75(7-8):712-717

Thaliblastine exhibits dose dependent cytotoxic effect on HL-60, HL-60/DOX, RHE and HD-MY-2 leukemia cells. Additionally, typical for apoptosis oligonucleosomal DNA fragmentation could be detected in leukemia cells treated with thaliblastine. Moreover, an MDR-phenotype reversing effect of thaliblastine was also identified.  相似文献   

Effects of racing on reticulocyte concentrations in Greyhounds     

S.J. Horvath  C.G. Couto  K. Yant  K. Kontur  L. Bohenko  M.C. Iazbik  L.M. Marín  D. Hudson  J. Chase  M. Frye  D.B. DeNicola 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2014,43(1):15-23

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Virus interference between H7N2 low pathogenic avian influenza virus and lentogenic Newcastle disease virus in experimental co-infections in chickens and turkeys     

Mar Costa-Hurtado  Claudio L Afonso  Patti J Miller  Erica Spackman  Darrell R Kapczynski  David E Swayne  Eric Shepherd  Diane Smith  Aniko Zsak  Mary Pantin-Jackwood 《Veterinary research》2014,45(1):1

Low pathogenicity avian influenza virus (LPAIV) and lentogenic Newcastle disease virus (lNDV) are commonly reported causes of respiratory disease in poultry worldwide with similar clinical and pathobiological presentation. Co-infections do occur but are not easily detected, and the impact of co-infections on pathobiology is unknown. In this study chickens and turkeys were infected with a lNDV vaccine strain (LaSota) and a H7N2 LPAIV (A/turkey/VA/SEP-67/2002) simultaneously or sequentially three days apart. No clinical signs were observed in chickens co-infected with the lNDV and LPAIV or in chickens infected with the viruses individually. However, the pattern of virus shed was different with co-infected chickens, which excreted lower titers of lNDV and LPAIV at 2 and 3 days post inoculation (dpi) and higher titers at subsequent time points. All turkeys inoculated with the LPAIV, whether or not they were exposed to lNDV, presented mild clinical signs. Co-infection effects were more pronounced in turkeys than in chickens with reduction in the number of birds shedding virus and in virus titers, especially when LPAIV was followed by lNDV. In conclusion, co-infection of chickens or turkeys with lNDV and LPAIV affected the replication dynamics of these viruses but did not affect clinical signs. The effect on virus replication was different depending on the species and on the time of infection. These results suggest that infection with a heterologous virus may result in temporary competition for cell receptors or competent cells for replication, most likely interferon-mediated, which decreases with time.  相似文献   

Suppression of ovulation in the rat by an orally active antagonist of luteinizing hormone-releasing hormone   总被引：2，自引：0，他引：2  

M B Nekola  A Horvath  L J Ge  D H Coy  A V Schally 《Science (New York, N.Y.)》1982,218(4568):160-162

A synthetic antagonist of luteinizing hormone-releasing hormone blocked ovulation in rats in a dose-dependent manner when given by gavage on the afternoon of proestrus. Ovulation was delayed for at least 1 day in all animals given 2 milligrams of antogonist and in some of the animals treated with 1 or 0.5 milligram. Oral administration of 2 milligrams also blocked the preovulatory surge of luteinizing hormone. This demonstration that antagonists of luteinizing hormone-releasing hormone can have oral antiovulatory activity clearly enhances their therapeutic potential.  相似文献   

Spectroscopic Observation of the Formyl Cation in a Condensed Phase     

de Rege PJF  JA Gladysz  IT Horvath 《Science (New York, N.Y.)》1997,276(5313):776-779

The formyl cation, HCO+, has long been believed to be an important intermediate in the chemistry of carbon monoxide (CO) in acidic environments, but its spectroscopic observation in solution has been elusive. This species was generated by the reaction of CO with the liquid superacid hydrofluoric acid-antimony pentafluoride (HF-SbF5) under pressure and was observed by nuclear magnetic resonance and infrared spectroscopy. Equilibria between CO in the gas phase, CO dissolved in HF-SbF5, the SbF5 adduct of formyl fluoride, and HCO+ associated with several equilibrating anions of the type [SbxF5x+1]- are proposed to describe the system.  相似文献   

Montessori-method for dogs     

Birgit Horvath 《Journal of Veterinary Behavior: Clinical Applications and Research》2013,8(4):e36-e37

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Pemphigus foliaceus-like drug reaction in a 3-month-old crossbreed dog treated for juvenile cellulitis     

Horvath C  Neuber A  Litschauer B 《Veterinary dermatology》2007,18(5):353-359

Two weeks after administration of routine vaccinations, a 3-month-old, male crossbreed dog developed cutaneous lesions that were clinically and histopathologically consistent with a diagnosis of juvenile cellulitis. The patient was treated with systemic antibacterial, antibacterial ophthalmic ointment and nonsteroidal anti-inflammatory drugs. Within 1 week, new skin lesions that were clinically, histopathologically and immunohistochemically consistent with pemphigus foliaceus developed. The latter completely resolved following drug withdrawal, suggesting a pemphigus foliaceus-like drug reaction. However, the initial lesions persisted and required glucocorticoid therapy to effect resolution. To the authors' knowledge, this is the first reported case of a puppy developing juvenile cellulitis followed by a pemphigus foliaceus-like reaction shortly thereafter, in response to drug therapy.  相似文献   

Blood vitamin concentrations in privately owned dogs fed non-standardized commercial diets and after intake of diets with specified vitamin concentrations     

Tran JL  Horvath C  Krammer S  Höller U  Zentek J 《Journal of animal physiology and animal nutrition》2007,91(1-2):40-47

The objective was to investigate in a survey study the blood vitamin concentrations in healthy dogs fed non-specified commercial complete diets and in an intervention study to determine the effects of defined dietary vitamin intakes on blood vitamin levels and hair and skin condition. Sixty-four privately owned dogs, aged from 1 to 8 years, without history of skin or coat problems were included. All animals were fed commercial complete diets with uncertain vitamin concentrations before enrolment. The animals were assigned, according to weight and gender, to four groups with graded vitamin intakes. The blood vitamin levels and skin and coat quality of the dogs were investigated at days 0 and day 122. Coat and hair condition was not influenced by the experimental diets. The retinol concentrations were reduced at the end of the experiment compared with the baseline levels, retinyl esters were not influenced. 25-Hydroxycholecalciferol decreased in all groups, alpha-tocopherol was constant or tended to decrease. Ascorbic acid, thiamine pyrophosphate and riboflavin concentrations were not affected by treatment, flavin adenine dinucleotide and pyridoxal-5'-phosphate were partially reduced on day 122. Cobalamin, pantothenate and biotin concentrations increased with higher dietary intakes, folate levels in tendency. In conclusion, this study gives a survey of blood vitamin concentrations in healthy dogs and provides a data base for the evaluation of the vitamin status in health and disease.  相似文献   

Occurrence and Sources of Polycyclic Aromatic Hydrocarbons in the Tisza River and its Romanian Tributaries     

Mihail Simion Beldean-Galea  Radu Mihăiescu  Viorel Arghiuş  Adina Croitoru  Csaba Horvath  Virginia Coman 《Water, air, and soil pollution》2016,227(10):377

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