Suppression of ovarian progesterone production in dairy cows using an implant of GnRH-agonist (deslorelin) for the purpose of evaluating progesterone metabolism     

AR RABIEE  KL MACMILLAN  F SCHWARZENBERGER  D THALLER  MJ RATHBONE  TE TRIGG 《Australian veterinary journal》2001,79(10):690-694

OBJECTIVE: To evaluate the potential of an implant of a GnRH-agonist (deslorelin) to create a progesterone free animal suitable for studying progesterone (P4) metabolism in intact cows by measuring blood P4 and faecal P4 metabolites. METHODS: Experiment 1: Eighteen non-lactating cycling Holstein-Friesian cows, 4 to 7 years old, were allocated to one of three groups to study plasma P4 concentrations preceding an intravaginal insert. These groups comprised: i) a deslorelin group (GnRH-agonist implanted); ii) a PGF group receiving two injections of prostaglandin (PGF2alpha) 12 days apart; and, iii) an ovariectomised (OVX) group. An intravaginal device (CIDR) was inserted into the vagina of each animal and left in place for 11 days. Plasma P4 concentrations were measured during the study period. Experiment 2: Twelve non-lactating cycling Holstein-Friesian cows, 4 to 7 years old, were allocated to two groups: i) a deslorelin group (GnRH-agonist implanted); and ii) an ovariectomised group. Plasma P4 and faecal P4 metabolites (20-oxo-pregnanes, 20alpha-OH and 20beta-OH) were monitored for a period of 5 weeks. RESULTS: Experiment 1: Average plasma P4 concentration did not differ between the three groups (1.28, 1.43 and 1.55 ng/mL for deslorelin, OVX and PGF cows, respectively, P = 0.8) during the period of supplementation. Experiment 2: There was no difference in plasma P4 (mean plasma P4 < 0.02 ng/mL, P = 0.9) and faecal P4 metabolites between deslorelin and OVX cows 2 weeks after the implantation (P = 0.7). CONCLUSIONS: These data showed that a GnRH-agonist (deslorelin) implant may be used as an alternative to ovariectomy to create a progesterone free animal suitable for studying the metabolism of administered P4.  相似文献   

THE AMERICAN SOCIETY OF BACTERIOLOGISTS     

Conn HW 《Science (New York, N.Y.)》1901,13(322):321-331

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BOOK REVIEW     

KL Stafford 《Australian veterinary journal》2005,83(8):505-505

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Theileria orientalis: a review     

JG Watts  MC Playford  KL Hickey 《New Zealand veterinary journal》2016,64(1):3-9

Theileria orientalis (also known historically as T. sergenti and T. buffeli) is responsible for benign or non-transforming theileriosis, and exerts its major effect through erythrocyte destruction. The life cycle of T. orientalis is essentially similar to that of other Theileria species, except that the schizonts do not induce transformation and fatal lymphoproliferation. The pathogenesis of anaemia as a result of infection is not clearly established and may be multifaceted. Clinical signs of weakness, reluctance to walk and abortion are early but non-specific indications of disease, particularly if accompanied by a history of cattle being moved. Physical examination may reveal pallor (pale eyes, vaginal mucosa), pyrexia, and elevated heart and respiratory rates. T. orientalis is an economically important parasite of cattle in New Zealand, Australia and Japan, especially where naïve animals are introduced into an endemic area or in animals under stress. Increased awareness of the risks posed by the parasite is required to enable management practices to be implemented to minimise its impact.  相似文献   

CERTIFIED METHYLEN BLUE     

Conn HJ 《Science (New York, N.Y.)》1923,58(1490):41-42

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RELATIVE IMPORTANCE OF FUNGI AND BACTERIA IN SOIL     

Conn HJ 《Science (New York, N.Y.)》1916,44(1146):857-858

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UNIVERSITY AND EDUCATIONAL NOTES     

Conn HJ 《Science (New York, N.Y.)》1923,57(1483):638-639

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THE STANDARDIZATION OF BIOLOGICAL STAINS     

Conn HJ 《Science (New York, N.Y.)》1923,57(1462):24-25

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AN ABSTRACTING SERVICE FOR TECHNIQUE IN BIOLOGICAL MICROSCOPY     

Conn HJ 《Science (New York, N.Y.)》1935,82(2114):12-13

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Insecticidal and anti-microbial activity of bio-oil derived from fast pyrolysis of lignin,cellulose, and hemicellulose     

Hossain  Mohammad M.  Scott  Ian M.  McGarvey  Brian D.  Conn  Kenneth  Ferrante  Lorenzo  Berruti  Franco  Briens  Cedric 《Journal of pest science》2015,88(1):171-179

Journal of Pest Science - Conflicting views regarding synthetic pesticides include the successful use as pest management tools for agriculture and forestry on one hand and the threats to components...  相似文献