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1.
Frida Westgren Tove Hjorth Margareta Uhlhorn Pernille E Etterlin Charles J Ley 《Acta veterinaria Scandinavica》2014,56(1):25
An eleven-year-old Chinese Crested Powder Puff dog presented with polydipsia/polyuria, inappetence, diarrhea and vomiting underwent an ultrasound-guided percutaneous liver biopsy. Two days post-biopsy the clinical condition of the dog acutely deteriorated with fever, dyspnea, ataxia and subcutaneous emphysema. Radiographs and ultrasound showed focal severe hepatic emphysema in the region of the previous liver biopsy. Post-mortem examination revealed chronic hepatitis with dissecting fibrosis, acute hepatitis with hemorrhage and in the hindlimb musculature extensive hemorrhage and necrosis. Pure cultures of the gas producing bacteria Clostridium perfringens were isolated in samples from the hind limb musculature. We propose that the hepatic emphysema in the region of the biopsy site was a result of a clostridial infection. 相似文献
2.
A. Flåøyen H. Hjorth Tønnesen H. Grønstøl J. Karlsen 《Veterinary research communications》1991,15(6):483-487
It has been suggested that saponins produced by Narthecium ossifragum (Bog asphodel) may be the direct cause of the toxicity leading to the hepatogenous photosensitivity disease alveld seen in Norwegian lambs. Lambs fed large quantities of freeze-dried N. ossifragum did not develop alveld. Chemical investigations on the freeze-dried material and fresh N. ossifragum showed no difference in their saponin content. These results indicate that alveld is not caused solely by the saponins produced by N. ossifragum. 相似文献
3.
That pesticide use in public areas in Denmark has been significantly reduced during the period 1995 to 2002 is shown when comparing three surveys carried out by the Danish Forest and Landscape Research Institute (DFLRI) with funding from the Danish Environmental Protection Agency. During that period, the total registered public use of pesticides was reduced from 28.8 tonnes active ingredients to 6.3 tonnes, corresponding to a 78% reduction. In 2002, the Danish counties and state institutions had reduced their total pesticide use by 80% and 73%, respectively, compared to 1995 figures. Similarly, the Danish municipalities reduced their use by 83% from 1995 to 2002. Surveys of municipal pesticide use carried out in 1995, 2000 and 2002 have been used as the basis for determining the factors that have influenced municipal reductions of pesticide use. The 2000 and 2002 trends can be explained partly on the basis of the figures for 1995 use. The trend for 2002 can also be partially explained by the political parties in power in the municipalities during the phase-out period. The models used account for up to 30% of the total variations, meaning that the pesticide use of individual municipalities is very much influenced by other, non-definable factors such as tradition. 相似文献
4.
Hjorth M Mondolot L Buatois B Andary C Rapior S Kudsk P Mathiassen SK Ravn HW 《Pest management science》2006,62(6):515-521
A new, easy, rapid and relatively inexpensive method using microscopy has been developed for the detection of herbicide effects in leaves of grass weed species displaying no visual signs of damage. The method has potential to be used as a tool to indicate future death of grass species due to herbicide exposure by observing phytochemical effects, i.e. early-warning effects. In the present study, Apera spica-venti (L.) Beauv., Bromus hordeaceus L., Alopecurus myosuroides Huds., Lolium perenne L. and Poa annua L. were exposed to lethal rates of four herbicides with different mode of action. The herbicides investigated were the thiocarbamate: prosulfocarb, the sulfonylurea: iodosulfuron, the aryloxyphenoxypropionate: fenoxaprop-P-ethyl and the organophosphate glyphosate. Autofluorescence of leaves was studied under a microscope using ultraviolet and blue light. The fluorescence of leaves treated to enhance flavonoids was also examined. To confirm the results, microspectrofluorometry was performed. Effects indicating future death of the grasses were observed in visually healthy leaves following treatment with prosulfocarb, glyphosate and iodosulfuron. No changes were detected following treatment with fenoxaprop-P-ethyl. After exposure to glyphosate or iodosulfuron, changes in the content of flavonoids and other compounds with a conjugation system and rigid structure and a decrease in the content of chlorophyll were detected in the leaves. Prosulfocarb treatment resulted in changes in the content of flavonoids and other compounds with a conjugation system and rigid structure and an increase in the content of chlorophyll in the leaves. The results obtained from microspectrofluorometry indicated that exposure to prosulfocarb caused a reduction in the flavonoids quercetin, naringenin and/or naringin. 相似文献
5.
FDG‐PET IN HEALTHY AND EPILEPTIC LAGOTTO ROMAGNOLO DOGS AND CHANGES IN BRAIN GLUCOSE UPTAKE WITH AGE
Tarja S. Jokinen Merja Haaparanta‐Solin Ranno Viitmaa Tove J. Grönroos Jarkko Johansson Luciana Bergamasco Marjatta Snellman Liisa Metsähonkala 《Veterinary radiology & ultrasound》2014,55(3):331-341
Regional cerebral metabolism and blood flow can be measured noninvasively with positron emission tomography (PET). 2‐[18F]fluoro‐2‐deoxy‐D‐glucose (FDG) widely serves as a PET tracer in human patients with epilepsy to identify the seizure focus. The goal of this prospective study was to determine whether juvenile or adult dogs with focal‐onset epilepsy exhibit abnormal cerebral glucose uptake interictally and whether glucose uptake changes with age. We used FDG‐PET to examine six Lagotto Romagnolo dogs with juvenile epilepsy, two dogs with adult‐onset epilepsy, and five control dogs of the same breed at different ages. Three researchers unaware of dog clinical status visually analyzed co‐registered PET and magnetic resonance imaging (MRI) images. Results of the visual PET analyses were compared with electroencephalography (EEG) results. In semiquantitative analysis, relative standard uptake values (SUV) of regions of interest (ROI) drawn to different brain regions were compared between epileptic and control dogs. Visual analysis revealed areas of hypometabolism interictally in five out of six dogs with juvenile epilepsy in the occipital, temporal, and parietal cortex. Changes in EEG occurred in three of these dogs in the same areas where PET showed cortical hypometabolism. Visual analysis showed no abnormalities in cerebral glucose uptake in dogs with adult‐onset epilepsy. Semiquantitative analysis detected no differences between epileptic and control dogs. This result emphasizes the importance of visual analysis in FDG‐PET studies of epileptic dogs. A change in glucose uptake was also detected with age. Glucose uptake values increased between dog ages of 8 and 28 weeks and then remained constant. 相似文献
6.
Castro-Tirado AJ Zapatero-Osorio MR Caon N Cairos LM Hjorth J Pedersen H Andersen MI Gorosabel J Bartolini C Guarnieri A Piccioni A Frontera F Masetti N Palazzi E Pian E Greiner J Hudec R Sagar R Pandey AK Mohan V Yadav RK Nilakshi Bjornsson G Jakobsson P Burud I et al 《Science (New York, N.Y.)》1999,283(5410):2069-2073
Broad-band (ultraviolet to near-infrared) observations of the intense gamma ray burst GRB 990123 started approximately 8.5 hours after the event and continued until 18 February 1999. When combined with other data, in particular from the Robotic Telescope and Transient Source Experiment (ROTSE) and the Hubble Space Telescope (HST), evidence emerges for a smoothly declining light curve, suggesting some color dependence that could be related to a cooling break passing the ultraviolet-optical band at about 1 day after the high-energy event. The steeper decline rate seen after 1.5 to 2 days may be evidence for a collimated jet pointing toward the observer. 相似文献
7.
Levan AJ Tanvir NR Cenko SB Perley DA Wiersema K Bloom JS Fruchter AS Postigo Ade U O'Brien PT Butler N van der Horst AJ Leloudas G Morgan AN Misra K Bower GC Farihi J Tunnicliffe RL Modjaz M Silverman JM Hjorth J Thöne C Cucchiara A Cerón JM Castro-Tirado AJ Arnold JA Bremer M Brodie JP Carroll T Cooper MC Curran PA Cutri RM Ehle J Forbes D Fynbo J Gorosabel J Graham J Hoffman DI Guziy S Jakobsson P Kamble A Kerr T Kasliwal MM Kouveliotou C Kocevski D Law NM Nugent PE Ofek EO Poznanski D 《Science (New York, N.Y.)》2011,333(6039):199-202
Variable x-ray and γ-ray emission is characteristic of the most extreme physical processes in the universe. We present multiwavelength observations of a unique γ-ray-selected transient detected by the Swift satellite, accompanied by bright emission across the electromagnetic spectrum, and whose properties are unlike any previously observed source. We pinpoint the event to the center of a small, star-forming galaxy at redshift z = 0.3534. Its high-energy emission has lasted much longer than any γ-ray burst, whereas its peak luminosity was ～100 times higher than bright active galactic nuclei. The association of the outburst with the center of its host galaxy suggests that this phenomenon has its origin in a rare mechanism involving the massive black hole in the nucleus of that galaxy. 相似文献
8.
Oberg J Fall T Lilliehöök I 《Veterinary clinical pathology / American Society for Veterinary Clinical Pathology》2011,40(1):66-73
Background: Measurement of canine serum insulin has relied on methods developed to measure human insulin. A species‐optimized test for measurement of serum insulin in dogs is now commercially available. Objective: The purpose of this study was to validate the canine ELISA for determination of serum insulin concentration in dogs. Methods: Precision was determined by evaluating intra‐ and interassay coefficient of variation (CV), and accuracy was determined by dilution and spike recovery studies. A method comparison study with samples from 34 clinically healthy dogs and 73 dogs examined for various illnesses and disorders (“patients”) was performed using the canine ELISA and an ELISA for human insulin. Biologic relevance of the canine assay was evaluated by measuring insulin in samples collected from 8 healthy dogs after administration of glucagon. A stability study was preformed with 6 samples stored at 20°C, 4–8°C, and ?20°C. Results: For the canine ELISA, intra‐ and interassay CVs were 4.3–7.8% and 4.4–7.7%, respectively. Mean recovery after dilution was 99% and recovery after spiking with porcine insulin was 116%. The canine and human ELISAs correlated well (r2=.94 for healthy dogs, r2=.88 for patient samples). After glucagon injection serum insulin concentrations increased significantly in 8 dogs. Insulin was stable for 30 days in 6 serum samples stored at ?20°C and in most samples for 8 days at 4–8°C. Insulin was stable for <3 days at room temperature (20°C). Conclusions: The new canine serum insulin ELISA had good precision and accuracy and correlated well with the previously used assay. 相似文献
9.
Laryngeal fistula in cattle 总被引：2，自引：0，他引：2
P Hjorth 《Nordisk veterinaermedicin》1973,25(2):88-90
10.
Diabetes mellitus in a population of 180,000 insured dogs: incidence, survival, and breed distribution 总被引：1，自引：0，他引：1
Fall T Hamlin HH Hedhammar A Kämpe O Egenvall A 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2007,21(6):1209-1216
BACKGROUND: Canine diabetes mellitus (DM) is a common endocrinopathy with an unclear etiology. For a better understanding of the underlying mechanisms, there is a need for comprehensive epidemiologic studies. Earlier studies have shown that the risk of disease is higher in certain dog breeds. HYPOTHESIS: Incidence, age of onset, survival and sex proportion of DM vary by breed. ANIMALS: Data from a cohort of 182,087 insured dogs aged 5-12 years accounting for 652,898 dog-years at risk were studied retrospectively. METHODS: Incidence rates by sex, breed, and geography were calculated with exact denominators. Age-specific incidence and survival after 1st DM claim were computed with Cox's regression and Kaplan-Meier survival function. Multivariable survival analysis was performed for the outcome diagnosis of DM with age, sex, and geography tested as fixed effects, previous endocrine or pancreatic diseases tested as time-dependent covariates, and breed tested as a random effect. RESULTS: The mean age at 1st insurance claim for the 860 DM dogs (72% females) was 8.6 years. The incidence of DM was 13 cases per 10,000 dog-years at risk. Australian Terriers, Samoyeds, Swedish Elkhounds, and Swedish Lapphunds were found to have the highest incidence. The proportion of females with DM varied significantly among breeds. Swedish Elkhounds, Beagles, Norwegian Elkhounds, and Border Collies that developed DM were almost exclusively females. The multivariable model showed that breed, previous hyperadrenocorticism, and female sex were risk factors for developing DM. Median survival time was 57 days after 1st claim. Excluding the 223 dogs that died within 1 day, the median survival time was 2 years after 1st claim of DM. CONCLUSION: The significant breed-specific sex and age differences shown in this study indicate that genetic variation could make breeds more or less susceptible to different types of DM. 相似文献