Synthesis and in-vitro antifungal activity of 6-trifluoromethyipyrazolo[3,4-6d]pyrimidin-4(5H)-thiones     

Chiara B. Vicentini  Tiziana Poli  Augusto C. Veronese  Vincenzo Brandolini  Maurizio Manfrini  Mario Guarneri  Paolo Giori 《Pest management science》1989,27(1):77-83

Twelve 6-trifluoromethylpyrazolo[3,4-d]pyrimidin-4(5H)-thiones were prepared by the reaction between 4-thiocarbamoyl-5-aminopyrazoles and trifluoroacetic anhydride. They were tested in vitro for antifungal activity against a series of phytopathogenic fungi of different taxonomic classes. The EC50 and MIC values of four compounds were comparable or inferior to those of reference commercial fungicides in controlling Sclerotinia minor, Corticium solani and Phytium ultimum.  相似文献   

Synthesis of some new ether derivatives of hydroquinone and their ovicidal activity against the two-spotted spider mite (Tetranychus urticae Koch)     

Franco Bettarini  Pietro Massardo  Paolo Piccardi  Vincenzo Caprioli 《Pest management science》1986,17(5):465-472

A new class of compounds derived from hydroquinone ethers showed high and predominantly ovicidal activity against the two-spotted spider mite, Tetranychus urticae Koch. The sequence of compounds synthesised and the factors which appeared to have contributed most to the discovery of these promising acaricides are presented.  相似文献   

Fungitoxicity of 5-aminoisoxazole-4-thiocyanate derivatives     

Chiara B. Vicentini  Vincenzo Brandolini  Tiziana Poli  Mario Guarneri  Paolo Giori 《Pest management science》1992,34(2):127-131

3-Methyl-5-(acyl/alkyl)aminoisoxazole-4-thiocyanates were prepared by rhodanation of N-acyl/alkyl-3-methyl-5-isoxazolamines. These products were tested for antifungal activity against a series of phytopathogenic fungi of different taxonomic classes. Some of the compounds showed interesting in-vitro activity. The more active compound in the in-vitro test displayed a moderate preventive activity against Plasmopara viticola, Alternaria solani and Pyricularia recondita.  相似文献   

Processing tomato quality as affected by irrigation scheduling   总被引：5，自引：0，他引：5  

Fabio Favati  Stella Lovelli  Fernanda Galgano  Vito Miccolis  Teodoro Di Tommaso  Vincenzo Candido 《Scientia Horticulturae》2009,122(4):562-571

In Southern Italy the paucity of water is a very important problem and due to the fundamental importance of the water for the processing tomato, in this study the influence of irrigation on processing tomato quality was investigated in the years 2002 and 2003. A hybrid processing tomato (Lycopersicon esculentum L. Mill cv. Ability) was treated with different water regimes obtained combining amount of water and irrigation interval. The effects of the trials were evaluated taking into account the physical and chemical characteristics of the fruits, as well as the content in antioxidants moieties. Furthermore, the relationship among all the quality parameters and the seasonal amount of irrigation water was evaluated.The results, comparing different water regimes obtained combining amount of water and irrigation interval, gave useful indications on the possibility to improve nutritional tomato quality by reducing irrigation water during tomato cropping. In particular, relatively to the Mediterranean areas of tomato cultivation and to the texture of the soil considered in this study, the best compromise between quality and quantity of the processing tomato fruit was achieved both with the extension of the irrigation interval (L40 or L60) and with the limitation of irrigation volume for the second part of the tomato crop cycle (thesis 100-50). Extending the irrigation interval and limiting irrigation volume for the second part of the tomato crop cycle, appeared to be the best management strategy to optimize the yield and nutritional quality of processing tomato.  相似文献   

Lateral caudal axial pattern flap in 13 dogs          下载免费PDF全文

Vincenzo Montinaro  Federico Massari  Luca Vezzoni  Julius M. Liptak  Rod C. Straw  Larie Allen  Ryan P. Cavanaugh  John Berg  Ronan S. Doyle  Paolo Buracco  Giorgio Romanelli 《Veterinary surgery : VS》2015,44(5):642-647

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Effect of Testosterone Administration and Spiking on Reproductive Success of Broiler Breeder Flocks          下载免费PDF全文

B Ordas  S Vahedi  A Seidavi  M Rahati  V Laudadio  V Tufarelli 《Reproduction in domestic animals》2015,50(5):820-825

Age negatively affects reproductive success of broiler breeder flocks. One of the main hormones involved in the change of fertility with the age is testosterone (TT). The introduction of young males at later production stages of broiler flocks is known as spiking and is expected to reduce the fertility decline with age. The aim of this study was to determine the effect of injection of different levels of TT and the effect of spiking on reproductive fitness of broiler breeder flocks. Two experiments were conducted on Ross 308 breeder flocks for 10 weeks (41–50 weeks of age). The experiment 1 included a control and three treatments corresponding to three doses of TT (0.1, 0.2 and 0.3 cc), while the experiment 2 included a control and one treatment corresponding to spiking. The lower dose of TT (0.1 cc) and the spiking clearly slowed down the decline in hatchability. Therefore, either the external administration of TT to the males when the natural concentration of TT starts to decline or spiking the breeder flock with young roosters could contribute to improve reproductive success in later stages of the production cycle in broiler breeder flocks.  相似文献   

Effect of different levels of dietary sweet orange (Citrus sinensis) peel extract on humoral immune system responses in broiler chickens          下载免费PDF全文

Zohreh Pourhossein  Ali Ahmad Alaw Qotbi  Alireza Seidavi  Vito Laudadio  Gerardo Centoducati  Vincenzo Tufarelli 《Animal Science Journal》2015,86(1):105-110

This experiment was conducted to evaluate the effects of different levels of sweet orange (Citrus sinensis) peel extract (SOPE) on humoral immune system responses in broiler chickens. Three hundred 1‐day broilers (Ross‐308) were randomly allocated to treatments varying in supplemental SOPE added in the drinking water. The experimental groups consisted of three treatments fed for 42 days as follows: a control treatment without feed extract, a treatment containing 1000 ppm of SOPE and a treatment containing 1250 ppm of SOPE. All treatments were isocaloric and isonitrogenous. Broilers were vaccinated with Newcastle disease virus (NDV), avian influenza (AI), infectious bursal disease (IBD) and infectious bronchitis virus (IBV) vaccines. Antibody titer response to sheep red blood cells (SRBC) was higher in the group fed 1250 ppm of SOPE (P < 0.05) as well as for immunoglobulin G (IgG) and IgM. Similarly, antibody titer responses to all vaccines were constantly elevated (P < 0.05) by SOPE enrichment in a dose‐dependent manner. Relative weights of spleen and bursa of Fabricius were unaffected by treatments. Dietary SOPE supplementation may improve the immune response and diseases resistance, indicating that it can constitute a useful additive in broiler feeding. Thus, supplying SOPE in rations may help to improve relative immune response in broiler chickens.  相似文献   

Natural occurrence of ochratoxin A and antioxidant activities of green and roasted coffees and corresponding byproducts     

Napolitano A  Fogliano V  Tafuri A  Ritieni A 《Journal of agricultural and food chemistry》2007,55(25):10499-10504

Ochratoxin A is an important mycotoxin that can enter the human food chain in cereals, wine, coffee, spices, beer, cocoa, dried fruits, and pork meats. Coffee is one of the most common beverages and, consequently, it has a potential risk factor for human health related to ochratoxin A exposure. In this study, coffee and corresponding byproducts from seven different geographic regions were investigated for ochratoxin A natural occurrence by HPLC-FLD, nutritional characterization, and antioxidant activities by spectrophotometric assay. The research focused on composition changes in coffee during the processing step "from field to cup". Costa Rica and Indian green coffees were the most contaminated samples, with 13 and 11 microg/kg, respectively, while the Ethiopian coffee was the least contaminated, with 3.8 microg/kg of ochratoxin A. The reduction of ochratoxin A contamination during the roasting step was comparable for any samples that were considered under the recommended level of 4 microg/kg. Total dietary fibers ranged from 58.7% for Vietnam and 48.6% for Ivory Coast in green coffees and ranged from 58.6% for Costa Rica to 61.2% for India in roasted coffee. Coffee silverskin byproduct obtained from Ivory Coast was the highest, with 69.2 and 64.2% of insoluble dietary fibers, respectively.  相似文献   

Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration     

Cengiz Gokbulut  Hande Sultan Yalinkilinc  Dilek Aksit  Vincenzo Veneziano 《Canadian journal of veterinary research》2014,78(4):316-320

Since there is no registered anthelmintic drug available for use in goats, extra-label use of drugs is a common practice in most countries. The aim of the present study was to compare the pharmacokinetic disposition of levamisole (LVM)-oxyclozanide (OXZ) combination in sheep and goats following per os administration. Goats (n = 8) and sheep (n = 8) 12- to 16-months-old were used for this study. The animals received tablet formulation of LVM and OXZ combination orally at a dose of 7.5 mg/kg and 15 mg/kg body weight, respectively. Blood samples were collected by jugular vein at different times between 5 min and 120 h after drug administrations. The plasma concentrations of LVM and OXZ were analyzed by HPLC following liquid-liquid phase extraction procedures. The plasma concentrations and systemic availabilities of both LVM and OXZ in goats were lower and the plasma persistence of LVM was shorter compared with those observed in sheep. Terminal half-lives (t_1/2λz) of both molecules are shorter in goats compared with those in sheep. Goats treated with LVM-OXZ combination at the recommended dose for sheep may result in a reduced efficacy, because of under-dosing, which may increase the risk of drug resistance in parasites. Increased or repeated dose could be a strategy to provide higher plasma concentration and thus to improve the efficacy against the target parasites in goats compared with sheep. However, some adverse reactions may occur since LVM has relatively very narrow therapeutic index due to its nicotine-like structure and effect.  相似文献   

Long-term Electrocardiography Recording with Holter Monitoring in 15 Donkeys     

Jacopo Guccione  Diego Piantedosi  Antonio Di Loria  Vincenzo Veneziano  Paolo Ciaramella 《Journal of Equine Veterinary Science》2014

The heart rates (HR) and rhythms of 15 healthy donkeys of various ages, both sexes, and various breeds were analyzed throughout 24-hour Holter monitoring. The animals were evaluated at rest in their daily environment without the presence of investigators causing stress, using a three-channel digital Holter recorder. Analysis revealed a maximal HR range from 62.5 to 93.7 beats/min (mean, 72.50 ± 7.51 beats/min), whereas the minimal HR ranged from 29.7 to 42.2 beats/min (mean, 34.90 ± 4.22 beats/min). The daily mean HR was 47.55 ± 3.70 beats/min. The daytime mean HR was 49.39 ± 2.77 beats/min, whereas the night time rate was 46.22 ± 4.38 beats/min. Sinus bradycardia and sinus tachycardia were detected in 7 and 10 of 15 studied donkeys, respectively. Cardiac dysrhythmias due to high vagal tone such as sinoatrial heart block and second-degree atrioventricular heart block were occasionally recorded in 1 and 3 donkeys, respectively. A higher mean HR and fewer cardiac dysrhythmias were observed in donkeys than in horses and ponies at rest. These findings could be justified by differences in the autonomic nervous system tone.  相似文献