Differential regulation on C5 expression in goose versus mammals by glucose/palmitate provides a potential protection for goose fatty liver     

Zidi Jin  Long Liu  Cheng Xu  Chunchi Yan  Shuo Li  Tuoyu Geng  Daoqing Gong 《Animal Science Journal》2021,92(1):e13672

Goose fatty liver is a specific type of nonalcoholic fatty liver that is protected from harmful effects associated with severe steatosis. Our previous findings suggest that suppression of the complement C5 may be relevant, but the mechanism is unclear. Therefore, in this study, we first verified the expression pattern of complement genes (including C5) during goose fatty liver formation and then determined the liver fat content and fatty acid composition by high-performance liquid chromatography (HPLC), followed by selecting the differential metabolites to treat HepG2, goose and mouse primary hepatocytes, aiming to explore the mechanism of C5 and inflammation suppression in goose fatty liver. The data confirmed the suppression of complement genes (including C5) in goose fatty livers. Moreover, fat content was significantly higher in fatty liver versus normal ones, with oleic acid and palmitic acid dominantly accounting for the difference. In line with this, high concentration of palmitate led to down regulation of C5 expression in goose primary hepatocytes whereas upregulation in mouse primary hepatocytes and HepG2 cells. In conclusion, regulation on C5 expression by fatty liver related factors including high level of palmitic acid may contribute to the protection of goose liver from severe hepatic steatosis.  相似文献   

佐剂对鸡补体水平影响的研究     

马本江  王君伟 《黑龙江畜牧兽医》1993,(10):1-3

６０只未免疫的伊莎褐雄鸡雏分成４组，于２４日龄开始用试管法以５０％溶血度为标准样检测补体。３１日时Ａ，Ｂ，Ｃ三组分别皮下注射司盘－８０＋白油，氢氧化铝胶和ＢＣＧ，Ｄ组对照；４６日龄时再次注射。从３１日龄至５６日龄每隔５天检测一次。结果表明，佐剂使鸡的补体水平普遍升高。于每次注射后第５天达到高峰，第１０天左右接近正常。其中ＢＣＧ影响现大，并于５１日龄时天对照组异显著（０．０１＜Ｐ＜０．０５）．  相似文献   

行列式定义间的等价性及某些性质的证明     

周恩 《河北北方学院学报(自然科学版)》2005,21(4):11-14,23

给出行列式两种定义的等价性，并且由第二种定义证明了行列式的一些性质．  相似文献   

一类二维加权积分数值求积方法及其误差分析     

吴一刚  侯首萍 《北京农学院学报》2007,22(3):66-68

针对一类二维加权积分的数值计算方法及误差分析进行研究,参照一维广义高斯积分数值求积方法提出一种具有较高代数精度的计算方法并对其误差做分析,同时给出几个简明的结果。这些结果可用到诸如小波分解,图像处理与多分辨数字信号处理等领域。  相似文献   

Tresca与Mises屈服理论的两种简明比较法   总被引：1，自引：0，他引：1  

白英 《内蒙古农业大学学报(自然科学版)》2004,25(3):60-62

本文采用代数法和应力圆面积法对Tresca和Mises屈服理论进行了简明的定量分析比较，其结论与文献[4]、[5]和[6]相同。此方法简单明了，应用到教学中收到了良好的效果，且耗时很少。  相似文献   

反应网络的物料平衡一致性校验     

范伟云  夏璐 《广西农业生物科学》1997,(1)

通过对反应网络的物料平衡分析，提出了反应网络的物料平衡一致性校验方程，并用于反应网络的数据校正和推测  相似文献   

闭式Leontief模型为可行的一个实用的判定程序     

陈神灿 《福建农林大学学报(自然科学版)》1998,(3)

设Ｔ是某闭式Ｌｅｏｎｔｉｅｆ投入产出模型的投入矩阵，如果有正向量Ｘ使得Ｘ≥ＴＸ，则称该模型为可行的．本文给出闭式Ｌｅｏｎｔｉｅｆ模型是否可行的一个实用的判定程序．  相似文献   

A review of stand basal area growth models     

Sun Hong-gang Zhang Jian-guo Duan Ai-guo He Cai-yun 《中国林学(英文版)》2007,9(1):85-94

Growth and yield modeling has a long history in forestry. The methods of measuring the growth of stand basal area have evolved from those developed in the U.S.A. and Germany during the last century. Stand basal area modeling has progressed rapidly since the first widely used model was published by the U.S. Forest Service. Over the years, a variety of models have been developed for predicting the growth and yield of uneven/even-aged stands using stand-level approaches. The modeling methodology has not only moved from an empirical approach to a more ecological process-based approach but also accommodated a variety of techniques such as: 1) simultaneous equation methods, 2) difference models, 3) artificial neural network techniques, 4) linear/nonlinear regres-sion models, and 5) matrix models. Empirical models using statistical methods were developed to reproduce accurately and precisely field observations. In contrast, process models have a shorter history, developed originally as research and education tools with the aim of increasing the understanding of cause and effect relationships. Empirical and process models can be married into hybrid mod-els in which the shortcomings of both component approaches can, to some extent, be overcome. Algebraic difference forms of stand basal area models which consist of stand age, stand density and site quality can fully describe stand growth dynamics. This paper reviews the current literature regarding stand basal area models, discusses the basic types of models and their merits and outlines recent progress in modeling growth and dynamics of stand basal area. Future trends involving algebraic difference forms, good fitting variables and model types into stand basal area modeling strategies are discussed.  相似文献   

Depletion of serum alternative complement pathway activity in gilthead seabream caused by α-tocopherol and n-3 HUFA dietary deficiencies     

D. Montero  L. Tort  M.S. Izquierdo  L. Robaina  J.M. Vergara 《Fish physiology and biochemistry》1998,18(4):399-407

Studies on the alternative complement pathway (ACP) activity in fish have suggested the particular relevance of this pathway as a non-specific immune mechanism being its activation directly related with the availability of certain nutrients. In the present study ACP activity in gilthead seabream fed different dietary levels of a-tocopherol and n-3 HUFA deficiencies was studied under different stress conditions (overcrowding and repetitive chasing).A reduction in ACP activity was found when diets with deficiencies in -tocopherol and n-3 HUFA were assayed at any of the experimental conditions assayed. Levels of plasma cortisol were similar to those of fish after crowding stress subjected to dietary deficiencies at low stocking density, suggesting that dietary deficiencies produced a chronic elevation of cortisol. When fish were subjected to repetitive chasing, plasma cortisol from fish fed control diet showed a progressive increase whereas plasma cortisol levels from both dietary deficient groups showed a transitory peak 4 days after the beginning of the repetitive chasing. However, ACP activity levels of fish fed deficient diets remained lower than the control group and constant during chasing period. These results suggest that both a-tocopherol and n-3 HUFA nutritional deficiencies rather than stress are an important determinant of fish complement activity.  相似文献   

Immunostimulant effects of nucleotide isolated from yeast RNA on carp, Cyprinus carpio L.   总被引：2，自引：0，他引：2  

M Sakai  K Taniguchi  K Mamoto  H Ogawa  & M Tabata 《Journal of fish diseases》2001,24(8):433-438

Nucleotides from yeast RNA were evaluated for their ability to enhance the non-specific immune responses in carp, Cyprinus carpio . Oral administration of nucleotides to fish daily for 3 days resulted in enhanced responses of phagocytic and nitroblue tetrazolium (NBT) activities in kidney phagocytic cells. This activation of kidney cells was observed for at least 10 days post-treatment. The serum complement and lysozyme activities also increased in fish treated with nucleotides. Furthermore, the number of Aeromonas hydrophila in nucleotide-treated fish significantly decreased in the blood, kidney and liver after intraperitoneal injection. Thus yeast nucleotides appear to enhance non-specific immune responses in fish.  相似文献