氟对骨组织代谢调节因子的影响   总被引：1，自引：0，他引：1  

李术  徐世文  康世良 《动物医学进展》2002,23(4):26-28

过量氟不仅对骨细胞具有直接作用，而且可通过骨代谢调节因子（甲状旁腺素、骨钙素、降钙素）的间接作用，引起骨损害。因此，认识骨代谢调节因子，对深入探讨氟病具有重要的理论意义。  相似文献   

利用自制骨炭除氟剂处理农村高氟地下水研究     

陈涛  杨晓瑛  朱宝余 《中国农村水利水电》2011,(8)

在不同实验条件下将家畜骨制成骨炭除氟剂,通过除氟效果的比较筛选出最佳除氟剂制备方法。利用所制得的骨炭进行除氟静态吸附实验,研究了骨炭对氟的吸附效果以及温度、pH和地下水中常见阴阳离子等不同影响因素对骨炭除氟效果的影响。实验结果表明温度对骨炭除氟效果影响不大;低pH条件有利于骨炭对氟的去除;地下水常见阴阳离子中,Ca2＋和Mg2＋对骨炭除氟有一定的促进作用,而阴离子则起到不同程度的抑制作用。除氟后的骨炭可以利用NaOH浸泡方法进行再生,经三次再生后其吸附容量仍可达原来的94.3%,说明骨炭除氟剂具有良好的再生能力且可反复用于水中除氟。  相似文献   

不同配比南极磷虾粉饲料对网箱养殖俄罗斯鲟生长及氟累积的影响     

龚洋洋  黄艳青  陆建学  黄洪亮  高露姣  夏永涛  张涛  庄平 《海洋渔业》2015,37(2):164-170

配制南极磷虾粉替代饲料中鱼粉比例分别为0%、10%、20%、30%的4组饲料饲喂俄罗斯鲟(Acipenser gueldenstaedtii)200 d后,分析南极磷虾粉替代部分鱼粉对网箱养殖俄罗斯鲟生长和鱼体组织氟残留的影响。结果表明:(1)随着南极磷虾粉替代比例的升高,俄罗斯鲟的末重、增重、特定生长率、蛋白质效率先上升后下降,饲料系数先降低后升高,10%组显著高于对照组和其它试验组(P0.05);(2)实验结束时,俄罗斯鲟肌肉、肝脏和鱼鳔的氟浓度低于检测限,但鳃、皮、脊骨和背骨呈现剂量浓度效应,各试验组较对照组显著升高(P0.05)。综上所述,在本实验条件下,在俄罗斯鲟饲料中加入10%比例的南极磷虾粉时获得最佳生长效果和较低的组织氟累积。  相似文献   

工业氟污染对山羊硬组织损害的研究   总被引：5，自引：1，他引：5  

王俊东  陈友发 《畜牧兽医学报》1992,23(2):141-145

40只6～10月龄本地山羊在氟重污染牧场放牧18个月,对逐月牧草水溶氟,不同时期骨氟、枯草期血钙及碱性磷酸酶作了测定。同时应用X射线及扫描电镜对下颌、肋骨与牙齿结构作了观察。结果指出,随着骨氟增加,血钙降低、碱性磷酸酶升高、骨皮质变薄、密度降低、骨表面疏松多孔,牙齿磨灭不齐、钙化不良、釉质与本质结构改变。干早气候是枯草期牧草氟升高的先决条件,枯草期牧草高氟与钙的负平衡是形成骨质疏松的主要原因,而青草或与枯草期牧草氟含量及动物缺钙程度的不同是引起牙齿磨灭不齐、缩短寿命的关键因素。  相似文献   

The Effects of Replacing Dicalcium Phosphate with Busumbu Rock Phosphate on Performance and the Mechanical Properties of Bone in Growing Chicks   总被引：1，自引：0，他引：1  

Odongo NE  Plaizier J  van Straaten P  McBride B 《Tropical animal health and production》2002,34(4):349-358

Three hundred, day-old broiler chicks, with an average initial weight of 41.8±1.79 g, were used in a 15-day study (10 birds per battery cage) to characterize their performance and fluorine status when dicalcium phosphate (DCP) was replaced by Busumbu rock phosphate (BRP) as the source of phosphorus in the chicks' ration. The treatments comprised a standard ration with BRP replacing 0, 25%, 50%, 75% or 100% of DCP. Replacing DCP with BRP significantly reduced the final weight of the chicks (p<0.01), feed intake (p<0.01), weight gains (p<0.01) and dry matter digestibility (p<0.05) but increased (p<0.05) the feed-to-gain ratio. True phosphorus absorption and the percentage of phosphorus in the tibia were not affected by increasing amounts of BRP in the diet. Increasing levels of BRP in the diet linearly reduced (p<0.01) the percentage bone ash, calcium, Ca:P ratio, ultimate breaking force, bending moment, stress, and modulus of elasticity. Leg stiffness, lameness, reduced feed intake, and a decline in general health were recorded in 10–40% of the chicks on 75% and 100% BRP, respectively. These results suggest that excessive ingestion of fluorine from the BRP caused the reduction in the chicks' performance.  相似文献   

Effects of sodium fluoride on hepatic toxicity in adult mice and their suckling pups     

Hanen Bouaziz  Kamel Jammoussi  Fatma Ayedi  Najiba Zeghal 《Pesticide biochemistry and physiology》2006,86(3):124-130

In this investigation, we have evaluated the effect of sodium fluoride (NaF) on hepatic function in pregnant and lactating mice and their suckling pups. Experiments were carried out on female Wistar mice given 500 ppm sodium fluoride (226 ppm fluoride ion) in their drinking water from the 15th day of pregnancy until day 14 after delivery. All mice were sacrificed on day 14 after parturition. Our results showed a significant decrease in serum levels of total protein and albumin, a marked hypoglycaemia and a significant decline in serum cholesterol and triglyceride levels in fluoride-treated mice and their pups. Whereas globulin and biluribin levels in serum were not significantly changed by NaF treatment. On the other hand, serum transaminase activities (aspartate transaminase; alanine transaminase), which well known as markers of liver function, were elevated indicating hepatic cells’ damage after treatment with fluoride. Lipid peroxidation increased in NaF-treated mice and pups, as revealed by high liver malondialdehyde levels, while serum total antioxidant status showed a significant decline. These biochemical modifications in NaF-treated mice also correspond histologically with extensive ballooning, hepatocellular necrosis and infiltration of mononuclear cells. These effects were not observed in controls.  相似文献   

不同氟水平对生长育肥猪毒性的研究     

陶新  许梓荣  汪以真 《中国兽医学报》2006,26(1):91-93

96头始重(24.14±1.12)kg的杜长大三元杂交猪,随机分为4组。第1组为对照组,饲喂基础日粮(含氟量37.39mg/kg),第2、3、4组分别饲喂含氟(以NaF形式添加)量为100、150、200mg/kg的日粮,研究日粮中不同氟水平对猪生长性能和血清某些生化指标的影响,并探讨了氟在肝、肾和肌肉中的沉积,饲料氟和粪氟、血清氟、尿氟之间的相关关系。结果表明,第3、4组猪增重与对照组相比分别降低8.86%(P<0.05)和9.81%(P<0.05),料重比分别升高7.36%(P<0.05)和8.07%(P<0.05)。第4组血清钙、镁、白蛋白含量和碱性磷酸酶的活力与对照组相比分别降低了17.33%(P<0.01)、29.91%(P<0.01)、10.75%(P<0.05)和33.71%(P<0.01)。第3、4组肝、肾和肌肉氟含量与对照组相比显著增加(P<0.05)。各试验组粪氟、血清氟、尿氟含量随饲料中氟含量的增加而升高,且各组间差异极显著(P<0.001),饲料氟与粪氟、血清氟、尿氟含量相关系数分别为0.943(P<0.01)、0.911(P<0.01)和0.959(P<0.01)。  相似文献   

Evaluation of propolis effects on some biochemical parameters in rats treated with sodium fluoride     

Gokhan Eraslan  Murat Kanbur 《Pesticide biochemistry and physiology》2007,88(3):273-283

The present study in which 42 female rats, each weighing 200−250 g, were used covered a period of 21 days. The animals were divided into six groups. The first group served as the control group, whereas Group 2 was administered propolis at a dose of 200 mg/kg/bw in drinking water for 21 days. Group 3 was first provided with normal drinking water for a period of 14 days, and was subsequently administered propolis at a dose of 200 mg/kg/bw in drinking water for 7 days. Group 4 was first given normal drinking water for 14 days, and was secondly administered 100 ppm fluoride as a sodium fluoride in drinking water for 7 days. Group 5 was first administered propolis alone at a dose of 200 mg/kg/bw in drinking water for 14 days, and was secondly administered 100 ppm fluoride in association with 200 mg/kg/bw propolis for 7 days. Finally, Group 6 was first provided with normal drinking water for 14 days, and was secondly administered 100 ppm fluoride in association 200 mg/kg/bw propolis for a period of 7 days. At the end of the 21st day, blood samples were collected from the heart of each animal into both heparinised tubes and tubes without anticoagulants. Glucose, triglyceride, cholesterol, total protein, and uric acid levels, and aspartate aminotransferase (AST), alanine aminotransferase (ALT), and alkaline phosphatase (ALP) activities in the serum, as well as malondialdehyde (MDA) levels, glutathione peroxidase (GSH-Px) in the plasma, erythrocyte superoxide dismutase (SOD) and catalase (CAT) activities were measured. When compared to the control group, statistical differences were determined to exist with respect to oxidative stress parameters which involved increase in MDA levels in Groups 4−6, decrease in SOD activity in Groups 4 and 6, increase in CAT activity in Groups 5 and 6, and decrease in GSH-Px activity in Groups 4 and 6. Furthermore, in comparison to the control group, significant differences were observed with respect to certain serum biochemical parameters, including decrease in glucose levels in Groups 5 and 6, decrease in triglyceride levels in Groups 2 and 4, decrease in cholesterol levels in Groups 2 and 5, decrease in the total protein level of Groups 4−6, decrease in the ALT activity of Groups 5 and 6, increase in the AST activity of Group 4, decrease in the ALP activity of Groups 2−6 and increase in the uric acid level of Group 2. In the groups that were administered propolis in association with fluoride, improvement was observed in some oxidative stress parameters and certain other biochemical parameters. Changes determined in the oxidative stress parameters (especially MDA and SOD) were indicative of the anti-radical activity of propolis on the free radicals generated by sodium fluoride. However, the values not drawing completely close to those of the control group can be explained with propolis not being able to completely eliminate the free radicals and the other adverse effects generated by fluoride.  相似文献   

熏蒸剂硫酰氟及熏蒸处理设备在我国的开发研究   总被引：2，自引：1，他引：1  

徐国淦 《植物检疫》1998,12(1):38-46

本文主要是介绍农业部植检所和有关研究单位与应用单位协作进行硫酰氟的应用技术方面的研究结果。具体介绍硫酰氟对植物、仓储害虫、林木蛀干害虫的毒性,对高等动物的毒理以及中毒治疗方法;硫酰氟熏蒸后的暂时残留和永久残留的分析测定结果;硫酰氟的常压和真空熏蒸技术及其在农林、植物检疫、卫生检疫、外贸、文史档案、轻纺、城建等方面大规模应用。另外简介圆筒仓循环熏蒸设备,手动式ＺＸ—３５０型、半自动式ＣＫ－ＺＸ—１５００型真空熏蒸机及有害生物处理机的开发研制及应用  相似文献   

Effect of ABA,arginine and sucrose on protein content of date palm somatic embryos     

Besma Sghaier  Walid Kriaa  Mouna Bahloul  Jesús V. Jorrín Novo  Noureddine Drira 《Scientia Horticulturae》2009

Abscisic acid (ABA), arginine and sucrose were evaluated for their effects on the morphology, germination rates and protein content of date palm somatic embryos (SE). Different concentrations of these supplements in the culture medium were used. The comparative study of SE length and thickness between treated and untreated SE revealed no differences, except for ABA (20 μM), which increased thickness. A decrease of water content (WC) in favor of an increase in dry weight (DW) was observed in all treated SE, especially with sucrose (90 g l⁻¹) and ABA (20 μM). Only ABA (20 and 4 μM) caused a proliferation rate of the cultures higher than those in the control. Although all the tested compounds increased protein content, ABA (20 μM) was more effective in protein enrichment than arginine and sucrose treatments. The SDS-PAGE protein profiles showed a significant difference between treated and untreated SE. A protein band of 22 kDa, identified as glutelin in a previous work, was accumulated after treatment with 20 μM ABA or 3 mM arginine. These findings may contribute to further understanding of the mechanisms involved in the accumulation of specific storage proteins in several plants.  相似文献