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1.
In order to identify variables obtained at admission that could be used to predict survival in septicemic foals, medical records of 65 foals diagnosed with septicemia were reviewed. Initially, variables were analyzed independently (univariate analysis) for association with survival. Of the physical examination and historical data examined using univariate analysis, the ability to stand at admission, respiratory rate ≥ 60 breaths per minute (bpm), and normal-appearing mucous membranes were significantly associated with survival. Foals with history of induced parturition were significantly less likely to survive. The following hematologic and serum biochemical variables determined at admission were significantly associated with survival: white blood cell count a 6,000 cells/μL, neutrophil count <4,000 cells/μL, serum albumin concentration <2.2 g/dL, serum glucose concentration <120 mg/ dL, blood pH ≥ 7.35, and positive base excess. The administration of plasma at admission was significantly associated with survival. Stepwise multiple logistic regression analysis was performed to evaluate the association between survival and variables identified as significantly associated with survival in bivariate analysis. The final multivariate model selected included the variables standing, duration of clinical signs (24-hour intervals) prior to admission, respiratory rate a 60 bpm, neutropenia (> 4,000 cells/μL), and neonatal age category. The probability of survival was significantly increased for foals that were standing, had a respiratory rate a 60 bpm, and that had a neutrophil count <4,000 cells/μL at admission. Probability of survival was significantly decreased for foals that had a longer duration of clinical signs prior to admission. For each 24 hours of duration, the estimated risk of death was increased by 5.8-fold.  相似文献   
2.
An eleven-year-old Chinese Crested Powder Puff dog presented with polydipsia/polyuria, inappetence, diarrhea and vomiting underwent an ultrasound-guided percutaneous liver biopsy. Two days post-biopsy the clinical condition of the dog acutely deteriorated with fever, dyspnea, ataxia and subcutaneous emphysema. Radiographs and ultrasound showed focal severe hepatic emphysema in the region of the previous liver biopsy. Post-mortem examination revealed chronic hepatitis with dissecting fibrosis, acute hepatitis with hemorrhage and in the hindlimb musculature extensive hemorrhage and necrosis. Pure cultures of the gas producing bacteria Clostridium perfringens were isolated in samples from the hind limb musculature. We propose that the hepatic emphysema in the region of the biopsy site was a result of a clostridial infection.  相似文献   
3.
An alpaca presented for emergency evaluation of respiratory distress. Physical examination revealed weakness, pyrexia, and a grade V/VI left apical holosystolic murmur. Initial thoracic examination and radiographs were consistent with left sided congestive heart failure. Blood cultures, echocardiographic evaluation, and necropsy findings established a diagnosis of bacterial endocarditis associated with a Listeria monocytogenes infection. Left ventricular endocarditis is uncommon in ruminants, and to the authors' knowledge there are no other reports of L. monocytogenes being the causative agent in an alpaca.  相似文献   
4.
中华鳖台湾群体耶尔森氏菌病的研究   总被引:3,自引:0,他引:3  
蔡完其 《水产学报》1999,23(2):174-180
从中华鳖台湾群体病鳖的肝脏分离到菌株97-7-2C,97-9-2A‘,用这两种菌株人工感染10-15g稚鳖,发病率和死亡率均为100%,经菌体形态特征,培养特性和生理生化反应测定,鉴定97-7-2C为小肠结肠炎耶尔森氏菌,97-9-2A’为结核耶尔森氏菌,这两种菌都会引起鳖败血症。  相似文献   
5.
This report presents a clinical case of enteritis and septicemia with subsequent death of an adult horse associated with Escherichia fergusonii, in Germany. The patient died within 24 hours after onset of clinical signs, including fever and erosive stomatitis. Major pathologic findings were severe, acute, fibrinous, and necrotizing enteritis; severe, acute, fibrinous endocarditis; as well as multiple, hyaline thrombi in blood vessels. E fergusonii and Escherichia coli were isolated in moderate to high amounts from the intestine, the tricuspid valve, and the liver. This article represents the first case report of lethal enteritis and septicemia associated with E fergusonii infection in a horse.  相似文献   
6.
中华鳖脑膜炎败血性黄杆菌病的研究   总被引:6,自引:0,他引:6  
从垂死病鳖的肝脏分离到96-12-Ⅳ菌株,用该菌株人工感染健康鳖,感染率100%,由感染发病鳖的肝脏到96-12-Ⅳ‘菌株,经生理生化反应测定,与96-12-Ⅳ菌株的测定结果一致,鉴定为脑炎败血性黄杆菌。该菌通过血道传播,侵袭全身各脏器,使各脏器组织发生变质性病变,淤血,出血,呈败血症。选择14种药物以纸片扩散法对该菌进行药敏试验,证实其中4种药物抑菌作用较强,用它们配制了鳖必康Ⅲ号,临床验证效果  相似文献   
7.
Escherichia coli (E. coli) is one of the common pathogenic bacteria in veterinary clinical infection. As an opportunistic microorganism, E. coli normally does not cause diseases. However, it causes infections under certain circumstance to domesticated animal and poultry, resulting in severe diarrhea, septicemia, and respiratory infections. Although there are increasing reports regarding the infections of E. coli to domestic animals and poultry, the infection of E. coli in dogs is relatively less reported, especially on septicemia and meningoencephalitis. Here, we reported the isolation and identification of an E. coli isolate named CEC-GZL17 from dogs characterized by septicemia and sudden death, and found that CEC-GZL17 is able to cause meningoencephalitis. Exploration on the potential mechanism underlying meningoencephalitis demonstrated that CEC-GZL17 infection significantly increases TNF-α expression and inhibits ZO-1 and occludin expressions in brain tissue, indicating that the E coli likely use the mechanism to penetrate the blood-brain barrier via disrupting tight junction architecture, thus leading to the invasion to brain tissue.  相似文献   
8.
文中较详细地描述了由金色葡萄球菌和溶血性链球菌引起的非洲败血症病例的巨体剖检,显微组织学特征和微生物学诊断结果。为这一珍稀猛兽的疾病研究提供了参考。  相似文献   
9.
Background: Increased synovial fibrinolytic activity (detected by increases in synovial D‐Dimer concentrations) has been observed in different joint diseases in humans and adult horses, presumably in order to minimize fibrin deposition within the joint and thus avoid its detrimental effects. Objective: To investigate fibrinolytic pathway activation in joint sepsis in foals by measuring synovial D‐Dimer concentrations. Animals: Eighteen septic foals with septic joints, 9 septic foals without septic joints, 9 systemically healthy foals with septic joint, and 3 controls are included. Methods: Prospective observational clinical study of foals admitted for septic arthritis. Synovial D‐Dimer concentration and routine synovial fluid analysis were performed. Diagnosis of joint sepsis was made whenever synovial total nucleated cell count was >30,000 cells/μL, synovial total protein >4 g/dL, and neutrophil percentage of >80%, or synovial fluid culture resulted positive. Results were compared among groups by general lineal models. Results: Synovial D‐Dimer concentration was significantly (P < .001) higher in the foals with septic joints compared with foals without joint disease (P < .001). Conclusions and Clinical Importance: Septic joint disease is associated with a marked increase of synovial D‐Dimer concentration (marked activation of the fibrinolytic activity) within the affected joint. Although further studies are needed, the measurement of synovial D‐Dimer concentration may be considered a complementary diagnostic marker of septic joint disease.  相似文献   
10.
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