| 一氧化氮对肉鸡肺血管重塑影响的研究进展 |
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| 引用本文： | 刘林艳,姜义宝,杨玉荣,梁宏德.一氧化氮对肉鸡肺血管重塑影响的研究进展[J].动物医学进展,2012,33(8):86-89. |
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| 作者姓名： | 刘林艳 姜义宝 杨玉荣 梁宏德 |
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| 作者单位： | 河南农业大学牧医工程学院,河南郑州,450002 |
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| 摘 要： | 肺血管重塑是肉鸡肺动脉高压综合征的重要病理学变化特征,虽然对其形成的机制尚未完全清楚,但众多细胞因子在其形成过程中起重要作用已得到共识。一氧化氮作为一种信号物质,在血管扩张、细胞增殖与凋亡、内皮素分泌与合成以及抗氧化等过程中发挥着重要的调控作用,显示了其在抑制肉鸡肺血管重塑、预防和治疗肺动脉高压发生方面有着广阔的应用前景。
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| 关 键 词： | 一氧化氮 肺动脉高压 肺血管重塑 肉鸡 |
Progress on Nitric Oxide to Pulmonary Vascular Remodeling in Broilers |
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| LIU Lin-yan
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JIANG Yi-bao
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YANG Yu-rong
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LIANG Hong-de.Progress on Nitric Oxide to Pulmonary Vascular Remodeling in Broilers[J].Progress In Veterinary Medicine,2012,33(8):86-89. |
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| Authors: | LIU Lin-yan JIANG Yi-bao YANG Yu-rong LIANG Hong-de |
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| Institution: | (College of Animal and Veterinary Engineering,Henan Agricultural University,Zhengzhou,Henan,450002,China) |
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| Abstract: | Pulmonary vascular remodeling is one of the important pathological bases of broiler pulmonary hypertension syndrome,although the mechanism of its formation has not been fully clear to us,a number of cytokines play an important role in pulmonary vascular remodeling forming process.Nitric oxide as a signal substance in vasodilation,cell proliferation and apoptosis plays an important role in secretion and synthesis of endothelin and anti-oxidant process,and nitric oxide has broad application prospects in the inhibition of pulmonary vascular remodeling,prevention and treatment of pulmonary hypertension in broilers. |
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| Keywords: | nitric oxide pulmonary hypertension pulmonary vascular remodeling broiler |
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