首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献，搜索用时 15 毫秒
1.
The concentrations of IgG, IgM, IgA and the specific sow colostrum trypsin inhibitor (SCTI) were measured by radial immunodiffusion in colostrum and milk samples from sows and in serum samples from their offspring during the suckling period. A clear time dependence was found for all the measured variates in both whey and serum. Statistically significant positive correlations were found between, on the one hand, concentrations of IgG and IgA, but not IgM, in sera from 39 suckling piglets 1 and 3 days old, and, on the other hand, concentrations of the same immunoglobulins and of the trypsin inhibitor in maternal colostrum (n = 7). Multiple regression analyses showed that at day 1 and day 3 the levels of both IgG and IgA in serum samples from the suckling piglets were positively influenced by both the SCTI and the IgG or IgA contents in maternal colostrum.  相似文献   

2.
The specific trypsin inhibitor in porcine colostrum first described by Laskowski et al. (1957) is assumed to protect maternal antibodies in colostrum during absorption from the gut of the neonatal piglets (Baintner 1973). Investigations of Jensen & Pedersen have shown that the serum levels of IgG and IgA in newborn suckling piglets depend on both the immunoglobulin and the trypsin inhibitor levels in the colostrum of their mothers. Accordingly, the sow colostrum trypsin inhibitor (SCTI) is essential in order to ensure optimal systemic antibody protection to the newborn and young piglets. The secretory IgA in colostrum and milk, which gives local passive immunity to the gastro-intestinal tract of the piglets (Bourne 1973), is assumed in itself to be relatively resistant against proteolytic degradation (Tomasi & Bienenstock 1968).  相似文献   

3.
Administration of heat inactivated Escherichia coli antigens by intramuscular and intramammary routes induced elevated antibody levels in sow serum and colostrum, predominantly associated with IgG. Colostral IgG accounted for approximately 80 per cent of the total antibody activity, and there was a similar distribution in the sera of one-day-old piglets. The additional antibody activity was carried almost entirely by IgM following intramuscular injections and was evenly distributed between IgM and IgA following intramammary stimulation. The distribution of antibody activity and all three major immunoglobulin classes in colostrum and milk from individual mammary glands was remarkably uniform. A similar uniformity was inferred for the ingestion and absorption of colostrum by individual piglets as judged by the contents of their blood sera during the neonatal period.  相似文献   

4.
本试验旨在探讨母猪日粮中添加低聚壳聚糖对哺乳仔猪生长、血液生化指标、抗氧化能力及免疫功能的影响。选用24头胎次、体重和预产期相近的健康大白猪母猪，随机分为3组，每组8个重复，每个重复1头母猪。对照组饲喂基础日粮，Ⅰ、Ⅱ组饲喂分别添加50和100 g/t低聚壳聚糖的基础日粮，试验从母猪妊娠第85天开始至分娩后第21天时结束。结果显示：①Ⅱ组哺乳仔猪腹泻率显著低于对照组和Ⅰ组（P < 0.05），Ⅰ组与对照组差异不显著（P > 0.05）；与对照组相比，Ⅰ、Ⅱ组仔猪21日龄体重显著提高（P < 0.05）。②Ⅰ组仔猪血浆乳酸脱氢酶（LDH）活性和甘油三酯（TG）浓度，Ⅱ组α-淀粉酶（α-AMY）、LDH活性和低密度脂蛋白（LDL）浓度均显著低于对照组（P < 0.05）。③Ⅱ组哺乳仔猪血清超氧化物歧化酶（SOD）活性，皮质醇、白介素-10（IL-10）、白介素-1β（IL-1β）、肿瘤坏死因子α（TNF-α）和干扰素-γ（IFN-γ）含量均显著高于对照组和Ⅰ组（P < 0.05），而丙二醛（MDA）浓度显著低于对照组（P < 0.05）。④低聚壳聚糖组母猪初乳中免疫球蛋白G（IgG）、IgA和IgM含量均显著高于对照组（P < 0.05）；Ⅰ组仔猪血清IgG和IgA含量、Ⅱ组仔猪血清IgA含量均显著高于对照组（P < 0.05）。综上所述，母猪日粮中添加一定量的低聚壳聚糖能够提高哺乳仔猪的抗氧化能力、增强机体免疫能力、降低腹泻率，从而提高哺乳仔猪生长性能。  相似文献   

5.
本试验旨在研究母猪饲粮添加β-羟基-β-甲基丁酸(HMB)对母猪繁殖性能及仔猪生长性能和免疫功能的影响。选取20头3～6胎次、妊娠74 d的"长×大"母猪,随机分成2组,每组10个重复,每个重复1头母猪,对照组饲喂基础饲粮,试验组在对照组基础饲粮中添加2 000 mg/kg HMB。试验从母猪妊娠第74天开始,至仔猪21日龄断奶结束。结果表明:与对照组相比,试验组仔猪初生个体重显著提高14.1%(P<0.05),仔猪7、21日龄窝重分别显著提高16.6%、11.7%(P<0.05),仔猪初生至7日龄、初生至21日龄窝增重分别显著提高28.3%和12.5%(P<0.05);与对照组相比,试验组母猪在妊娠第98天和分娩当天血清免疫球蛋白G(IgG)含量分别提高35.3%(P<0.01)、13.0%(P>0.05),免疫球蛋白M(IgM)含量分别提高34.7%(P<0.05)、12.6%(P>0.05);与对照组相比,试验组母猪初乳中IgG含量显著提高19.0%(P<0.05),分娩后第14天常乳中IgM含量显著提高21.4%(P<0.05);与对照组相比,试验组仔猪7日龄血浆IgG、IgM含量分别显著提高11.4%和40.1%(P<0.05)。上述结果提示,母猪妊娠后期及哺乳期饲粮中连续添加2 000 mg/kg HMB,可显著提高仔猪初生重和哺乳期增重,改善母猪及仔猪免疫功能。  相似文献   

6.
一种复方中草药添加剂对断奶仔猪免疫机能的影响   总被引：1，自引：0，他引：1  
选用同一保育舍的87头断奶仔猪进行饲养试验及血液采集和免疫指标测定。87头断奶仔猪随机分为2组,Ⅰ组为对照组,饲喂基础日粮;Ⅱ组为中药组,在基础日粮中添加1.5%的中草药添加剂。结果表明,血清免疫球蛋白:1个阶段(30 d)后,在IgM、IgA水平上,中药组与对照组相比,无显著差异(P0.05),在IgG水平上,中药组比对照组提高11.38%(P0.05)。2个阶段(60d)后,在IgM水平上,中药组比对照组提高12.46%(P0.05),在IgG、IgA水平上,中药组比对照组分别提高41.69%和21.33%(P0.01);淋巴细胞转化率:2个阶段后,中药组比对照组提高了15.79%(P0.05);猪瘟抗体水平和猪伪狂犬抗体水平:1个阶段后,中药组合格率比对照组都提高20%,阻断率(PI)分别改善3.86%(P0.05)和11.94%(P0.05)。2个阶段后,中药组合格率比对照组分别提高20%和30%,阻断率分别改善28.02%和24.83%(P0.01)。通过本试验初步判断:该复方中草药添加剂可显著提高断奶仔猪的免疫机能,增强机体免疫力。  相似文献   

7.
Two Bordetella bronchiseptica mutants, lacking the adenylate cyclase (Cya) or both Cya and pertactin (Prn), were compared with their parental strain NL1013 in their abilities to colonize the nose of neonate piglets and to induce local and systemic antibody responses against filamentous hemagglutinin (FHA) after intranasal (i.n.) inoculation. The number of bacteria recovered and the duration of infection in the nasal secretions were greater for the wild-type parent strain than for the Cya-deficient mutant, indicating that Cya plays an important role during B. bronchiseptica colonization of the nasal cavity. The double mutant did not colonize the nasal cavity and was less able to adhere to epithelial cells in vitro than the other two strains, supporting the hypothesis that Prn plays a major role in cell adhesion. In piglets inoculated with the wild type strain, anti-FHA IgM was found in the nasal secretions one week after inoculation, followed two weeks later by anti-FHA IgA; their presence was concomitant with decreases in bacterial counts. Anti-FHA IgG appeared at six weeks after infection in the serum. In contrast, i.n. inoculation with either mutant failed to induce a nasal secretory antibody response but did induce an earlier and higher IgM response in the serum than inoculation with the wild type strain. However, only the Cya-deficient mutant was able to prime the piglets for the development of a secondary nasal IgM and serum IgG response to FHA after intranasal inoculation with the wild type B. bronchiseptica.  相似文献   

8.
Newborn pups from 4 large litters were alloted to 6 groups to determine effect of time and route of administration on absorption of an alternate source of immunoglobulin. Selective absorption of specific classes of immunoglobulins was also investigated. The alternate source of immunoglobulin consisted of pooled serum that was administered either PO or SC. Control groups were either left with the dam (group C1) or fed milk replacer (group C2). Blood samples were collected from pups at birth and 24 hours. Immunoglobulin (IgA, IgG, IgM) concentrations were determined by use of radial immunodiffusion on samples of pooled serum, colostrum, and pups' serum (birth and 24 hours). Serum IgA concentration was less than the sensitivity of the procedure and was not included in the statistical analysis. Pups fed 8 ml of pooled serum at birth and 12 hours later (group T1) absorbed more (P less than 0.05) IgG and IgM than did group-C2 pups, but less (P less than 0.05) than did group-C1 pups. Pups fed 8 ml of pooled serum at 12 hours only had significant (P less than 0.05) increase of IgG concentration, but no absorption of IgM (P greater than 0.05) at 24 hours, compared with control pups (group C2). Pups administered 8 ml of pooled serum SC at birth (group SC1) had similar (P greater than 0.05) absorption of IgG and higher (P less than 0.05) absorption of IgM than did pups of group T1.(ABSTRACT TRUNCATED AT 250 WORDS)  相似文献   

9.
Studies were made of the immunoglobulin (Ig) in serums from umbilical cord of newborn pigs and maternal placenta. The neutralization test for porcine parvovirus and Japanese encephalitis virus was carried out with the serum of the sow and that of the umbilical cord of the newborn pig. Comparative studies of the serums from the dam and the umbilical cord were also done with gel filtration. Of 20 umbilical cord serum samples, IgG was seen in 5 samples (25%), IgA in 1 sample (5%), and IgM in 9 samples (45%). The amount of any 1 of the 3 classes of Ig in the serums was between 13.5 and 28.0 mg/dl. Among the samples examined, 1 had both IgG and IgA and 1 had IgG and IgM, but none had both IgA and IgM and none had 3 classes of immunoglobulins (i.e., IgG, IgA, and IgM). Only 7 samples (35%) did not have any class of Ig. The IgG disappeared from the blood of hysterectomy-produced colostrum-deprived pigs at 3 days of age, and IgM disappeared when pigs were 7 days of age. Neutralization antibodies of porcine parvovirus and Japanese encephalitis virus in maternal serum were not transferred to the fetus through the placenta. Results of immunohistologic surveys indicated that the sow's Ig were not transferred to the fetus through the placenta. Therefore, it is believed that the Ig in the porcine fetus might be synthesized in certain cells in the placental tissue, and the degree of production of the Ig in the placental tissues may differ in each case. The component, which seems to be Ig, was observed as the obscure band of the beta- to gamma-globulin area in serum of the umbilical cord. Comparison was made, with gel filtration, of maternal serum and serum from the umbilical cord of the newborn pig originating from the same sow. Seemingly, the IgG in the umbilical cord serum is mainly in the lower molecular weight fraction, whereas IgG in the sow's serum was distributed in the high to low molecular weight fractions.  相似文献   

10.
The aim of this experiment was conducted to study the effects of fermented Atractylodes chinensis on serum immune and biochemical indexes of weaned piglets. Ninety-six Landrace ×Large White weaned piglets with weaning weight (6.0±0.5) kg were randomly allocated to 6 groups with 4 replicates per group and 4 weaned piglets per replicate. The weaned piglets were subjected to the following 6 treatments for 28 days:Control group was fed with the basal diet,groups Ⅰ and Ⅱ were fed with antibiotics and 0.2% unfermented Atractylodes chinensis in basal diet,while groups Ⅲ,Ⅳ and Ⅴ were supplemented 0.1%,0.2% and 0.3% fermentated Atractylodes chinensis in basal diet,respectively. The results showed that the immune and biochemical index of weaned piglets in fermented Atractylodes chinensis group had different degrees of improvement compared with control group and group Ⅰ.In the whole experimental stage,comparing with control group,the serum IgA,IgG,IgM,TP and ALB of weaned piglets in group Ⅳ were increased 10.5%,10.0%,7.8%,21.0% and 15.6%,respectively,and the difference were significant (P < 0.05),and serum ALT content was significantly reduced 20.4% (P < 0.05).Compared with group Ⅰ,the serum IgA,IgG,IgM and TP of weaned piglets in group Ⅳ were increased 7.1%,3.8%,3.8% and 12.6%, respectively,the difference were significant (P < 0.05),while the serum ALB, AST and BUN of group Ⅳ were increased 1.0%, 9.5% and 15.0%, and the difference were not significant (P > 0.05), and serum ALT content was reduced 9.4% compared with the antibiotics group (P > 0.05).  相似文献   

11.
试验旨在研究发酵北苍术对断奶仔猪血清免疫指标和生化指标的影响。选取96头体况相近、断奶重为（6.0±0.5）kg的长白猪×大白猪二元杂交仔猪,随机分为6组,每组4个重复,每个重复4头猪。对照组饲喂基础日粮,Ⅰ组为抗生素组,在基础日粮中添加杆菌肽锌＋硫酸黏杆菌素,Ⅱ组在基础日粮中添加0.2%未发酵北苍术,Ⅲ、Ⅳ、Ⅴ组分别在基础日粮中添加0.1%、0.2%、0.3%发酵北苍术,试验期为28 d。结果显示,日粮中添加发酵北苍术组的断奶仔猪的血清各项免疫指标和生化指标较对照组及Ⅰ组均有不同程度的改善,其中Ⅳ组的效果最好。在整个试验阶段（断奶后28 d）,与对照组相比,Ⅳ组断奶仔猪血清中IgA、IgG、IgM、TP和ALB含量分别提高了10.5%、10.0%、7.8%、21.0%和15.6%,差异均显著（P < 0.05）,血清中ALT含量与对照组相比显著降低了20.4%（P < 0.05）;与Ⅰ组相比,Ⅳ组断奶仔猪血清中IgA、IgG、IgM、TP分别提高了7.1%、3.8%、3.8%、12.6%,差异均显著（P < 0.05）,而ALB、AST和BUN含量分别提高了1.0%、9.5%和15.0%,差异均不显著（P > 0.05）,血清中ALT含量与Ⅰ组相比降低了9.4%（P > 0.05）。  相似文献   

12.
The present results suggest that mannanoligosaccharides (MOS) included in a sow nutrition may affect its immune system and humoral antibody production in colostrum and milk, and thus increase the piglet immunity at the postnatal period. The studies involved sows of the Polish Landrace breed mated with boars (Hampshire x Duroc). In each experiment, the sows were assigned to two groups: control and experimental (MOS). Each group consisted of 16 sows managed in pens (2 animals in each) during pregnancy, whereas at farrowing and lactation period they were placed in individual pens. The basal diet during pregnancy (PR-S) and lactation (LC-S) period contained wheat (40% in experiment I--groups 1 and 2) or triticale (40% in experiment II--groups 3 and 4), as well as barley, soybean meal, soybean oil and mineral-vitamin premix. Throughout both experiments, the sows from the experimental group had a dietary supplement of mannanoligosaccharides (MOS) preparation for 4 of weeks prepartum and 4 weeks of post partum period. A level of the MOS supplementation (8 g of MOS per sow daily) based on the recommendations of the manufacturer. Blood samples were collected from the sows on days 84 (the start of trial) and 110 of pregnancy, after farrowing, and on day 21 of lactation period, while from the piglets at birth and on day 21 of age. Colostrum was collected between 1-3, 12, 24 and 48 h after farrowing. The blood samples taken from sows and piglets as well as the samples of sow colostrum and milk were evaluated for the presence of IgG, IgA and IgM antibodies. The present study has provided considerable evidence that MOS supplementation of sows feedstuff before and after farrowing (4 weeks before and 4 weeks after) exerts a positive effect on IgG content in the colostrum and plasma of sows and following this on serum IgG level in the suckling piglets. Higher level of colostral (passive) immunity influences positively body weight gain and survival rate of the piglets at weaning.  相似文献   

13.
Bronchial-associated immune development is critically important to protect neonates from respiratory infections. Herein, bronchial-associated immune development in formula-fed and sow-reared pigs is described. Colostrum-fed newborn piglets were fed medicated sow milk replacer formula beginning at 48 h of life or remained with the sow. Blood and tissues were sampled at one-week (d7) and three-weeks (d21) of age. Lymphocyte subpopulations, including T helper 2, cytotoxic T, memory T, and NK cells, in peripheral blood, mediastinal lymph nodes, and thoracic lymph nodes were identified using flow cytometry. Additionally, IL-1β, IL-6, IL-12, TNFα, TGF-β1, TGF-β2, IFNα, IFNβ, and dectin gene expression were analyzed by quantitative RT-PCR. Total IgG, IgM, and IgA concentrations in serum were analyzed. Dietary and developmental effects were observed. This set of baseline measurements provides a framework for future respiratory challenge studies where the effects of diet on the neonate's ability to resist and/or recover from infection can be tested.  相似文献   

14.
试验选用相近胎次(4-6胎)和分娩日龄(相差3d左右)的长×大二元母猪20头,随机分成4个处理组,各处理组哺乳仔猪均从5日龄开始补料,哺乳仔猪日粮中分别添加0、50、100和200 mg/kg的酵母-β1,3/1,6-葡聚糖,研究酵母β-1,3/1,6-葡聚糖对哺乳仔猪生长性能和免疫机能的影响。结果表明:哺乳仔猪日粮中添加酵母β-1,3/1,6-葡聚糖,对生产性能无显著影响,有降低仔猪腹泻率和死亡率的趋势;可显著提高外周血淋巴细胞转化率,血清IgA、IgG和IgM浓度(P<0.05),有提高血清溶菌酶活性的趋势。综合全期生长性能和免疫调节效果来看,哺乳仔猪日粮中β-1,3/1,6-葡聚糖适宜的添加剂量为50mg/kg。  相似文献   

15.
This experiment investigated the effects of supplementing the maternal diet with linseed oil (LSO) and soya bean oil (SBO) on immunoglobulins, the fatty acid composition and hepatic expression of lipid metabolism‐related genes in piglets. Multiparous sows (twenty‐four per diet) were fed on diets containing a supplement of either SBO or LSO during last week of gestation and lactation. The results indicated that supplementation of maternal diet with LSO could improve the weaning weight of piglets and average daily gain (ADG) (p < 0.05). The concentration of immunoglobulin G (IgG) and immunoglobulin A (IgA) was enhanced in sow plasma, colostrum and milk by the addition of LSO (p < 0.05). In addition, the concentration of 18: 3n‐3 fatty acids was higher in the milk of LSO sows. Meanwhile, maternal supplementation with LSO increased the levels of plasma IgG, IgA and the tissues n‐3 polyunsaturated fatty acid (PUFA) in piglets (p < 0.05). Correspondingly, the mRNA expression levels of hepatic ?5‐desaturase (D5D) and ?6‐desaturase (D6D) were higher, and fatty acid synthase (FAS) was lower in piglets from LSO‐fed sows when compared with that in the SBO group. In conclusion, LSO supplementation of the maternal diet increases immunoglobulins, modifies the fatty acid composition and affects the gene of D5D and D6D expression of piglets.  相似文献   

16.
The absorption by the neonatal gut of purified swine IgG isolated from maternal serum was studied in 91 motherless piglets raised without swine colostrum, to investigate some of the factors which influence absorption. Factors studied included the amount of IgG administered, the effect of bovine colostrum fed concurrently, the influence of starvation and the effect of lactose.Administration of iodinated IgG within 3 hours after birth resulted in the appearance of IgG in the piglet circulation in unaltered form. Immediate feeding of bovine colostrum followed by administration of iodinated IgG at 72 hours resulted in the appearance of only IgG digestion fragments in the circulation.Administration of 15 g of lactose during the first 24 hours reduced absorption of IgG by 26% compared to controls while treatment with 54 g of lactose reduced absorption by 94%. On the contrary, when bovine colostrum was administered immediately after purified IgG, the amount of swine IgG absorbed was 50–70% greater than in controls. Mature milk failed to have the same influence. Finally, in experiments in which the amount of purified swine IgG administered varied from 1.0 to 8.0 g, absorption was directly proportional to the amount administered. When these data were compared with data on naturally reared piglets, the same proportionality was seen and indicated a consistent 1:2.5 to 1:3 ratio of ingested IgG (g) to the maximal serum level of immunglobulin (mg/ml) resulting from absorption. IgA and IgM follow a similar pattern.The data are consistent with a regulated absorption mechanism, that appears to be lost very quickly after the initial ingestion of food. Heterologous protein and lactose alone can switch off this absorption mechanism, thus arguing against “gut closure” by a mechanism of receptor saturation by absorbed IgG. Bovine colostrum, when compared to mature milk, is able to augment the absorption of swine IgG by an unknown mechanism.  相似文献   

17.
本试验旨在研究给妊娠后期和哺乳期母猪补饲发酵芦笋下脚料对母猪和哺乳仔猪血清抗氧化能力、免疫功能和炎性因子含量的影响。选择15头膘情、胎次和预产期相近的妊娠母猪,随机分成3组,每组5个重复,每个重复1头猪。A(对照)、B和C组母猪每头每天分别补饲0、0.25和0.50 kg发酵芦笋下脚料。试验从母猪妊娠期的第85天开始至产后第21天结束。在母猪分娩和仔猪断奶时采集母猪耳静脉血液,在仔猪10和21日龄时采集仔猪前腔静脉血液,分别测定血清指标。结果表明:1)C组母猪在仔猪断奶时血清超氧化物歧化酶(T-SOD)活性极显著高于对照组(P0.01),在母猪分娩和仔猪断奶时血清丙二醛(MDA)含量均极显著低于对照组(P0.01)。B组哺乳仔猪10日龄时血清T-SOD活性显著高于对照组(P0.05),血清MDA含量显著低于对照组(P0.05)。2)C组母猪在母猪分娩时血清生长激素(GH)含量显著高于对照组(P0.05)。3)C组母猪在母猪分娩时血清免疫球蛋白A(IgA)和免疫球蛋白G(IgG)含量显著高于对照组(P0.05)。4)B和C组母猪血清白细胞介素-6(IL-6)含量在母猪分娩和仔猪断奶时均极显著低于对照组(P0.01)。C组母猪在仔猪断奶时血清肿瘤坏死因子-α(TNF-α)含量显著低于对照组(P0.05)。C组哺乳仔猪10日龄时血清TNF-α含量显著低于对照组(P0.05)。综上,每头母猪每天补饲0.50 kg发酵芦笋下脚料可增强其抗氧化能力和免疫功能,提高GH含量,减少炎性反应,同时可提高仔猪的抗氧化能力,减少炎性反应的发生。  相似文献   

18.
The aim of the study was the determination of IgA, IgM and IgG concentrations in porcine serum and colostrum, in order to evaluate their variations in the perinatal period, as well as to clarify whether there is a correlation between colostrum intake, initial level of immunoglobulins (Ig) in piglet serum and development of their own immunity. The mean IgA, IgM and IgG concentrations in sow serum 10 days before parturition were 1.58, 6.12 and 39.56 mg/ml, respectively. Seven days later only the IgG level was insignificantly lower (34.94 mg/ml, p = 0.55), while concentrations of IgA and IgM increased to 2.25 and 7.25 mg/ml, respectively (p = 0.23 and 0.62, respectively). The mean initial IgG concentration in colostrum at farrowing was 118.5 mg/ml and differed between sows. The average value of IgA in colostrum at birth was 23.8 mg/ml and decreased to 7.85 mg/ml at 6 hours (h) and to 4.59 mg/ml at 24 h after the onset of farrowing. IgM concentration at birth was 12.1 mg/ml and decreased to 4.23 mg/ml at 24 h postpartum. Positive relationships were found between concentrations of IgM and IgA in serum of piglets at 14 and 56 days of life (r = 0.41 and 0.80, respectively, p < or = 0.05) as well as for IgG concentration in the piglets serum at 7 days and 56 days of age (r = 0.48, p < or = 0.05). The above observations suggest that there is a correlation between the level of Ig in piglet serum in the first days of life and improvement of their own immunity.  相似文献   

19.
复方中草药制剂对仔猪免疫机能和抗氧化能力的影响   总被引：10，自引：3，他引：7  
在基础日粮中添加不同剂量的复方中草药制剂,研究其对仔猪免疫机能的影响。选取9窝(共90头)体重相近的杜×长×大三元杂交仔猪,随机分为3组,每组30头,分别饲喂基础日粮、基础日粮+复方中草药制剂1%、基础日粮+复方中草药制剂2%。试验期45 d。每组随机选取10头仔猪,分别在14、24、32、45日龄进行前腔静脉采血,测定部分免疫指标。结果表明,日粮中添加复方中草药制剂,能显著提高仔猪白细胞吞噬率、T-淋巴细胞转化率、血清免疫球蛋白含量和抗氧化酶活性,提高仔猪免疫力,减轻仔猪断奶应激。  相似文献   

20.
Antibody (immunoglobulin G (IgG), IgM or IgA) levels relative to ferritin in six foal sera (three male and three female) after birth (day 0 and 2, 6, 10, 20, 28, 36, 40, 52 and 56 weeks of age) were semi‐quantitatively measured with normalization with antibody activity to ferritin in one adult horse serum. After addition of horse spleen ferritin to the serum sample, the complex formed between antibodies to ferritin in the serum and ferritin was co‐immunoprecipitated using antibody to horse spleen ferritin. Antibody classes of the co‐immnoprecipitate were detected with antibodies specific for horse IgG, IgM or IgA heavy chain. Six adult horse serum samples were found to have ferritin‐binding activities in all immunoglobulin classes examined. Although ferritin antibody activities (IgG, IgM and IgA) were scant in the foal sera before sucking colostrum (day 0), their activities increased at 2 weeks of age. IgG antibodies showed a biphasic response and IgM antibody activity increased up to 40 weeks of age. Antibody (IgG, IgM and IgA) activities to ferritin in three colostrum samples were significantly higher than in adult horse serum samples. These results demonstrate that antibody to ferritin in foal serum is derived from colostrum after birth and is produced thereafter.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号