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禽白血病(avian leukosis,AL)是由反转录病毒科甲型反转录病毒属禽反转录病毒(avian leukosis virus,ALV)引起的以禽类造血组织中某些细胞成分增生为主的各种可传染的肿瘤疾病.根据病毒中和试验宿主范围和囊膜糖蛋白的特性及其它一系列标准,将禽白血病/肉瘤群病毒划分为A到J 10个亚群,其中分离自鸡的有6个亚群(A、B、C、D、E、J).鸡J亚群白血病病毒(ALV-J)是1988年Payne等[1,2]首次从商品代肉用鸡中分离到并鉴定出的鸡白血病病毒的一个新亚群. 相似文献
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有关禽白血病 (LL)危害的报道可以追溯到十七世纪后期 (Payne等 ,1 997)。尽管养鸡者已经意识到了白血病的危害。但由于这种病的流行所造成的经济损失很小 ,所以常被人们忽视。 1 988年 ,Payne等从肉用仔鸡中分离出一种新型的禽白血病病毒亚群 (ALV- J亚群 ) ,推翻了禽白血病病毒只存在于重型鸡体内的理论 (Payne等 ,1 991 )。直到发现被此病毒感染后的鸡表现出新的临床症状 ,禽白血病病毒 J亚群才得到肉用仔鸡养殖业的重视。1 997年人们发现野生型禽白血病病毒 J亚群 (AL V- J)与已发现的 LL相似。病毒感染禽群在性成熟后大约 1 7周… 相似文献
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家禽血管瘤的发生与防制 总被引：2，自引：1，他引：1
近几年来,与J亚群白血病病毒相关的禽白血病在我国禽群中广泛流行,其中,与禽白血病J亚群病毒(ALV-J)密切相关的血管瘤性疾病在我国蛋鸡群中呈蔓延趋势.本文就血管瘤的病原及发病机理、流行病学、临床症状、病理变化及防制的相关知识作一系统介绍. 相似文献
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Similarity between arthritis virus and Fahey-Crawley virus 总被引：1，自引：0，他引：1
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Response of cattle persistently infected with bovine virus diarrhoea virus to bovine leukosis virus 总被引：1，自引：0，他引：1
Six cattle persistently infected with bovine virus diarrhoea virus (BVDV) and seronegative, and two control, virus negative seropositive cattle were inoculated with lymphocytes infected with bovine leukosis virus (BLV). The two controls produced a normal immune response to BLV, developing antibodies at four and five weeks after inoculation. Two of the six cattle persistently infected with BVDV developed a strong antibody response by six weeks after inoculation with BLV. Four developed a depressed response to BLV, characterised in three by a 'hooking' reaction in the immunodiffusion test which persisted in successive bleedings but was interspersed occasionally by a weak positive reaction. In one of these animals, a series of 'hooking' reactions was followed by a number of negative results. The fourth animal remained serologically negative until 16 weeks after inoculation when a 'hooking' reaction was observed followed by a series of negative results. BLV was isolated from all the cattle persistently infected with BVDV at 42 or 58 weeks after inoculation regardless of whether the serum samples gave negative, 'hooking', weak positive or positive reactions in the immunodiffusion test. BLV was consistently isolated from the nasal secretions of a steer which was BVDV negative but seropositive. The possibility of decreased immune responsiveness to BLV in animals persistently infected with BVDV should be considered when formulating regulations governing the testing of animals for freedom from BLV. 相似文献
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A M Willis 《Veterinary Clinics of North America: Small Animal Practice》2000,30(5):971-986
Ophthalmic manifestations of FeLV or FIV infection can occur in all ocular tissues and may be manifestations of direct viral effects or secondary to viral-related malignant transformation. Additionally, the manifestations of common feline ophthalmic pathogens may be more severe and poorly responsive to therapy because of the immunosuppressive effects of FeLV or FIV infection. Prompt diagnosis of underlying viral infection in cats with ophthalmic disease is paramount for accurate diagnosis and prognosis and is required for appropriate therapeutic decision making. 相似文献
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Bovine virus diarrhoea-mucosal disease virus and border disease 总被引：1，自引：0，他引：1
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Schmallenberg virus (SBV), an arthropod borne pathogen, spread rapidly throughout the majority of Europe since 2011. It can cause a febrile disease, milk drop, diarrhea, and fetal malformation in ruminants. SBV, a member of the Simbu serogroup within the genus Orthobunyavirus, is closely related to Akabane virus (AKAV) and Aino virus (AINOV) among others. In the present study, 4 Holstein-Friesian calves were immunized twice four weeks apart with a multivalent, inactivated vaccine against AKAV and AINOV. Another 4 calves were kept as unvaccinated controls. All animals were clinically, serologically and virologically examined before and after challenge infection with SBV. AKAV- and AINOV-specific neutralizing antibodies were detected one week before challenge infection, while SBV-specific antibodies were detectable only thereafter. SBV genome was detected in all vaccinated animals and 3 out of 4 controls in serum samples taken after challenge infection. In conclusion, the investigated vaccine was not able to prevent an SBV-infection. Thus, vaccines for other related Simbu serogroup viruses can not substitute SBV-specific vaccines as an instrument for disease control. 相似文献
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In February 1999, 12 Dutch herds were vaccinated with a live bovine herpesvirus 1 vaccine from which bovine virus diarrhea virus (BVDV) could be isolated. All vaccine batches that were on the Dutch market and that had not yet reached the expiry date were tested for BVDV. In total, seven of 82 batches tested were found positive. Batch numbers TX3607, VB3914, VB3915, VB4046, TW3391, and TV3294 were positive for BVDV type 1, and batch number WG4622 was positive for BVDV type 2. This latter batch induced clinical signs of BVDV in an animal experiment with susceptible animals. 相似文献
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Persistent bovine virus diarrhoea virus infection in a bull 总被引：2，自引：0，他引：2
R M Barlow P F Nettleton A C Gardiner A Greig J R Campbell J M Bonn 《The Veterinary record》1986,118(12):321-324
Investigation of a sight defect in a pedigree bull, born as a result of artificial insemination and ovum transplantation, led to the finding that the animal was persistently infected with bovine virus diarrhoea virus. Virus was cultured from blood and from nasal and ocular swabs and was present in semen in high titre. At necropsy, virus was cultured from a wide range of tissues. The pathological findings are described and discussed as are the potential hazards of such infections. 相似文献