共查询到19条相似文献，搜索用时 187 毫秒
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多不饱和脂肪酸的营养功能及其在家禽生产中的应用 总被引：10，自引：0，他引：10
多不饱和脂肪酸是一类具有重要生物学功能的物质，主要包括n-3和n-6系列多不饱和脂肪酸，它们对脂类的代谢，机体的免疫，血液生化特性的影响，机体的生长发育及细胞膜功能的发挥和基因表达调控等许多方面起着重要的作用，本文主要介绍了多不饱和脂肪酸的营养功能及其作用的机理，并就其在家禽生产中的应用作一综述。 相似文献
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多不饱和脂肪酸（PUFA）是一种具有独特生物功能的物质，在机体免疫、脂质代谢、基因表达、细胞膜功能等方面有着重要的作用，对人和畜禽的健康有着重要的影响。本文综述了多不饱和脂肪酸主要的生物学功能，在养猪生产上的应用以及富含多不饱和脂肪酸猪肉产品的研究进展。 相似文献
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脂肪是一类重要的营养物质，是动物体内的重要能量来源，同时也是生物膜的组成成分，在细胞生化过程中也起着重要作用。研究发现，脂肪可通过对基因表达的影响，对代谢、生长发育以及细胞分化发挥重要的调控作用。此文综述了脂肪对动物基因表达的调控，尤其是多不饱和脂肪酸对动物基因表达的调控作用。 相似文献
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脂肪酸是一类重要的营养物质,是动物体内的能量来源,同时也是生物膜的组成成分,在细胞生化过程中也同样起着重要作用。研究发现,脂肪酸可通过对基因表达的影响,对代谢、生长发育以及细胞分化发挥重要的调控作用。真核生物基因表达的调控大致可分为转录前、转录、转录后、翻译和翻译后等5个阶段的调控。脂肪酸通过细胞膜受体信号途径和转录因子活化途径调节基因表达,而多不饱和脂肪酸主要从基因转录和mRNA的稳定性两个方面调节基因表达。文章综述了脂肪酸,尤其是多不饱和脂肪酸对基因表达的影响及调控机制。 相似文献
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多不饱和脂肪酸是所有细胞膜的重要成分,对机体的激素代谢和许多酶的活性起调控作用。动物和人自身不能合成亚油酸和亚麻酸,必需从外源食物中供给,因此对高多不饱和脂肪酸蛋的研究越来越受到关注。本文从鸡蛋中多不饱和脂肪酸的调控机制、多不饱和脂肪酸在鸡蛋中的富集、高多不饱和脂肪酸蛋的生产途径及研究应用现状等方面进行了简要综述,为其进一步开发研制提供参考。 相似文献
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In pigs fed a standard pig mash the contents of polyunsaturated fatty acids (PUFAs) of both the n-6 and n-3 series were significantly higher in the dark red mm adductores compared to the light coloured m longissimus lumborum. Perirenal fat had a higher concentration of saturated fatty acids (14:0,16:0, 18:0) than backfat, and a lower concentration of monounsaturated fatty acids, such as 16:ln-7 and 18:ln-9. Daily supplementation of 50 ml cod liver oil, rich in n-3 PUFAs, during the fourth and third week before slaughter led to a 1.4 to 1.7 times increase in the contents of n-3 PUFAs in muscles and fat depots. There was no difference between the incorporation of n-3 PUFAs in dark and light muscles. Perirenal fat contained more 20:5n-3 (EPA) and 22:6n-3 (DHA), but less 20:ln-9 (eicosenoic acid) than the backfat, after cod liver oil supplementation rich in these 3 fatty acids. Supplementation of cod liver oil reduced the n-6/n-3 fatty acid ratio in all anatomical locations examined. 相似文献
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Mast cells play a key role in the immune response. Thereby, the balance of oxidative metabolism is of importance in mast cell mediator synthesis and release. Fatty acids may modify mast cell function in several ways. In this study, we investigated the influence of polyunsaturated fatty acids (PUFAs) on oxidative parameters of a canine mastocytoma cell line. C2 cells were cultured in media supplemented with linoleic acid, arachidonic acid, alpha-linolenic acid and eicosapentaenoic acid, respectively. Production of reactive oxygen species (ROS) as well as lipid peroxides was tested. Furthermore, stressor-induced DNA damage was measured. Exposure of the cells to PUFAs resulted in a significant increase in the synthesis of both ROS and lipid peroxides. Distinct differences between the PUFAs tested underline the impact of the unsaturation degree of fatty acids as well as the position of double bonds on mast cells. 相似文献
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JE BAUER 《Australian veterinary journal》1994,71(10):342-345
SUMMARY The metabolism and clinical potential for dietary polyunsaturated fatty acids (PUFAs) modifications using oil supplements containing n-3 and n-6 fatty acids are reviewed. Their use in such disorders as renal disease, inflammatory and immune-related disorders, and dermatological conditions in dogs and cats is discussed. The influence of n-3 fatty acid-rich rations on the endotoxin response in horses is described. Progress has been made toward understanding the clinical potential for PUFAs in these species. However, they have not yet been shown to be efficacious in any of the conditions investigated. 相似文献
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长链多不饱和脂肪酸(LC PUFAs)在母猪营养中的作用经常被人们研究,因为猪场的盈利能力主要取决于母猪的繁殖性能。根据以往的研究结果,母猪妊娠期喂食ω-3 LC PUFAs可以减少前列腺素的合成,提高胚胎存活率和仔猪初生重;哺乳期饲喂ω-3 LC PUFAs可以提高乳汁中EPA和DHA含量,改善哺乳仔猪肠道健康和断奶重。文章论述了LC PUFAs(主要是ω-3)对现代高产母猪繁殖性能的影响,为在生产实践中合理添加应用LC PUFAs,提高母猪生产性能提供理论参考。 相似文献
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Expression analyses of candidate genes related to meat quality traits in squabs from two breeds of meat‐type pigeon 
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下载免费PDF全文 M. Ye M. Xu C. Chen Y. He M. Ding X. Ding W. Wei S. Yang B. Zhou 《Journal of animal physiology and animal nutrition》2018,102(3):727-735
In this study, meat quality traits were compared between squabs from two pigeon breeds: one Chinese indigenous breed, the Shiqi (SQ) meat‐type pigeon, and an imported breed, the white king (WK) meat‐type pigeon. Breed differences were detected in the content of intramuscular fat (IMF) in the breast muscle. SQ squabs had significantly higher IMF content than the WK birds. The shear force value (an objective measure of meat tenderness) of SQ birds was also relatively lower than that of the WK squabs. Further analysis of fatty acids profile revealed that SQ squabs exhibited significant advantage in the synthesis of polyunsaturated fatty acids, while WK squabs were significantly higher in the sum of monounsaturated fatty acids. Breast muscle in the SQ squabs was also significantly higher in the ratio of polyunsaturated fatty acids to saturated fatty acids, as well as the sum of omega 6 fatty acids. Variability of expression levels of functional genes in relation to fat accumulation and meat tenderness was analysed by qRT‐PCR. Gene expression analyses showed that the hepatic expression of LPL (lipoprotein lipase), FABP4 (fatty acid‐binding protein 4), and CAPN2 (calpain‐2) were significantly higher in the SQ squabs. In the breast muscle tissue, the FABP3 (fatty acid‐binding protein 3) and CAPN2mRNA abundance was significantly higher in SQ squabs. Our results suggested that these differentially expressed genes might be candidate genes used in the programmes of targeted selection for squabs with higher IMF content, tender meat, and more favourable fatty acids composition. 相似文献
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aterina Vackova Darko Bosnakovski Bodil Bjrndal Penka Yonkova Natalia Grigorova Zhenya Ivanova Georgi Penchev Galina Simeonova Lyuba Miteva Anelya Milanova Tatyana Vachkova Spaska Stanilova Ivan Penchev Georgiev 《Journal of animal physiology and animal nutrition》2019,103(3):925-934
Adipose‐derived stem cells (ADSCs) possess multipotent properties, and their proper functionality is essential for further development of metabolic disorders. In the current study, we explored the impact of two n‐3 LC‐PUFAs (long‐chain polyunsaturated fatty acids, DHA—docosahexaenoic; C22:6, and EPA—eicosapentaenoic; C20:5) on a specific profile of lipolytic‐related gene expressions in the in vitro‐differentiated subcutaneous and visceral ADSCs from rabbits. The subcutaneous and visceral ADSCs were obtained from 28‐day‐old New Zealand rabbits. The primary cells were cultured up to passage 4 and were induced for adipogenic differentiation. Thereafter, the differentiated cells were treated with 100 µg EPA or DHA for 48 hr. The total mRNA was isolated and target genes expression evaluated by real‐time RCR. The results demonstrated that treatment of rabbit ADSCs with n‐3 PUFAs significantly enhanced mRNA expression of Perilipin A, while the upregulation of leptin and Rab18 genes was seen mainly in ADSCs from visceral adipose tissue. Moreover, the EPA significantly enhanced PEDF (Pigment Derived Epithelium Factor) mRNA expression only in visceral cells. Collectively, the results suggest activation of an additional lipolysis pathway most evident in visceral cells. The data obtained in our study indicate that in vitro EPA up‐regulates the mRNA expression of the studied lipolysis‐associated genes stronger than DHA mainly in visceral rabbit ADSCs. 相似文献
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The fatty acid profile of subcutaneous fat and blood plasma in pruritic dogs and dogs without skin problems. 总被引：1，自引：1，他引：0 下载免费PDF全文
下载免费PDF全文 The purpose of this study was to investigate the concentration of polyunsaturated fatty acids (PUFAs) in subcutaneous fat and the relative amounts of PUFAs in plasma in two groups of dogs. Group 1 included dogs with a good skin and coat condition. Group 2 was comprised of dogs with pruritus and compatible clinical signs of atopy. The fatty acid composition of the total lipid fraction was analyzed by gas chromatography. In subcutaneous fat, the concentration of adrenic acid (22:4n-6) was lower in the group of pruritic dogs compared to dogs with healthy skin. The amount of dihomogammalinolenic acid (20:3n-6; DGLA) in plasma lipids from pruritic dogs was higher than in dogs without skin problems. 相似文献
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The fatty acid components of the plasma triglycerides and the phospholipid fractions of the red blood cells of a captive group of two African (Loxodonta africana) and four Asian (Elephas maximus) elephants were investigated. All the animals received the same diet of hay, fruits and vegetables, and concentrates. A comparison with data from free-ranging African elephants or Asian work-camp elephants showed that the captive elephants had lower proportions of polyunsaturated fatty acids (PUFAs), and for several lipid fractions a higher n-6:n-3 ratio, than their counterparts in the wild or under the more natural, in terms of diet, work-camp conditions. The difference in PUFA content was smaller in the African than in the Asian elephants. The captive Asian elephants tended to have lower levels of n-3 and total unsaturated fatty acids in their red blood cells than the captive African elephants. 相似文献
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Lecchi C Invernizzi G Agazzi A Ferroni M Pisani LF Savoini G Ceciliani F 《Veterinary journal (London, England : 1997)》2011,189(3):353-355
The in vitro effects of the ω-3 polyunsaturated fatty acids (PUFAs) eicosapentanoic acid (EPA) and docosahexanoic acid (DHA) on phagocytosis and the extracellular respiratory burst in caprine monocytes were assessed. Blood monocytes incubated with increasing concentrations of EPA or DHA (25–200 μM) demonstrated increased phagocytosis compared to unexposed monocytes. Generation of reactive oxygen species (ROS) was not markedly affected in the presence of EPA and DHA, except at 200 μM, at which concentrations monocyte viability was also reduced. 相似文献