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1.
为考察不同剂量的丹连花子宫灌注液对奶牛子宫内膜炎的临床治疗效果,选择患子宫内膜炎的患病奶牛50头,随机分为5组,每组10头,分别为丹连花子宫灌注液高、中、低剂量组,以及药物对照组和疾病对照组;另选健康奶牛10头作为健康对照。结果表明,丹连花子宫灌注液不同剂量组治疗后患病奶牛的临床症状明显改善,其中高、中剂量组奶牛子宫复旧完全,子宫颈黏液清亮,白细胞数明显减少,pH6.5~7.0,尿兰母检查阴性,治愈率60%,有效率90%,显著高于药物对照组(P<0.05),且血液白细胞数显著减少,其中中性粒细胞数极显著低于疾病对照组(P<0.01);不同剂量组血液生化指标无异常变化。表明丹连花子宫灌注液对奶牛子宫内膜炎有显著治疗效果,且使用安全,推荐临床使用剂量为100mL/次,子宫灌注给药,隔天1次,连用3次。  相似文献   

2.
目的 研究旨在通过试验观察中草药治疗奶牛子宫内膜炎疗效,以其为临床应用中草药治疗奶牛子宫内膜炎提供参考。方法 将60 头患子宫内膜炎奶牛,随机分成5 组,每组12 头,复方中草药高、中、低剂量组(分别子宫灌注150 mL/头、100 mL/头和50 mL/头)、土霉素组(子宫灌注50 mL/头)和对照组。结果 复方中草药中剂量组和高剂量组的总有效率为75.00%和83.33%,均高于土霉素组的总有效率66.67%;土霉素组在治疗结束后的平均发情天数缩短了14 d,所有复方中草药组的发情天数也缩短了11~19 d;3 个情期内土霉素组受胎率为50.00%,复方中草药组受胎率介于41.67%~66.67%之间。结论 复方中草药对奶牛子宫内膜炎的治疗效果优于土霉素,其中以高剂量组效果最佳。  相似文献   

3.
中草药“清宫促情灵”治疗奶牛子宫内膜炎的研究   总被引:1,自引:1,他引:0  
本试验采用复方中草药子宫灌注剂——"清宫促情灵"治疗各种类型的奶牛子宫内膜炎,以验证其治疗效果。具体方法是:用输精管将"清宫促情灵"注入子宫内,每次100mL,隔天一次。经对21头患有各种类型子宫内膜炎的奶牛进行治疗,病轻的1~3次即可治愈,病重的或慢性的病牛经4~5次治愈,严重的6~8次治愈。结果表明该药对奶牛子宫内膜炎疗效显著。  相似文献   

4.
选取临床自然发生子宫内膜炎的奶牛80头。将发病奶牛随机分为"宫康"高、中、低剂量组和青霉素对照组,采用子宫灌注途径给药,2日1次,连续3次给药后,停药观察7 d。结果"宫康"高剂量组与中剂量组对子宫内膜炎的疗效优于青霉素对照组和"宫康"低剂量组。"宫康"是中药制剂,对家畜无毒副作用,无刺激性,因此可作为治疗奶牛子宫内膜炎的首选药物。  相似文献   

5.
鱼腥草子宫灌注液对奶牛子宫内膜炎的临床效果观察   总被引:3,自引:0,他引:3  
为进一步评价鱼腥草子宫灌注液对奶牛子宫内膜炎的临床效果和安全性,在内蒙古呼和浩特和包头地区奶牛场开展了临床试验.该试验从呼和浩特和包头地区伊利、蒙牛乳业所属奶牛园区、奶牛养殖公司、奶牛联社的8家奶牛场选择377头有临床症状的子宫内膜炎患牛,对3个批次的药物进行临床药效观察.依据不同病情分为轻度、中度、重度子宫内膜炎3个治疗组,各组又用3个批次的药物进行相同给药处理,均按相同剂量60 mL/(次·头),一次性子宫内灌注药物原液,隔日给药1次,连续3次为1个疗程,给药后观察10d.统计分析鱼腥草子宫灌注液对不同程度子宫内膜炎的治疗效果及不同批次药效的差异性.结果表明,3个批次的鱼腥草子宫灌注液治疗同等程度奶牛子宫内膜炎,疗效基本相近,经x2检验,差异不显著(P >0.05),表明药物质量和药效稳定一致;鱼腥草子宫灌注液对奶牛子宫内膜炎的总有效率为94.7%,总显效率为86.2%;相同给药剂量和次数对轻度(卡他性子宫内膜炎)、中度(黏性脓性子宫内膜炎)、重度(脓性子宫内膜炎)的有效率分别为100%、90.1%、82.8%,显效率分别为94.5%、81.2%和63.8%,经x2检验表明,轻、重度2个病情组存在极显著差异(P<0.01).所有使用鱼腥草子宫灌注液的患牛,均未见全身或局部过敏反应及局部刺激性反应,具有较高的安全性.  相似文献   

6.
清宫助孕液治疗奶牛子宫内膜炎临床试验   总被引:1,自引:0,他引:1  
为研究"清宫助孕液"治疗奶牛子宫内膜炎的临床疗效,本试验将临床确诊为子宫内膜炎的奶牛80头,随机分为"清宫助孕液"治疗组和药物对照组,每组分别为60头和20头,治疗组采用直肠把握法将清宫助孕液子宫灌注,每次100 mL,隔日一次,4次为一疗程;对照药物将青霉素100万单位、链霉素100万单位,用生理盐水50mL稀释后,子宫灌注,隔日一次,4次为一疗程。结果表明,试验组治疗60头,治愈52头,治愈率86.67%,显效3头,显效率5.0%;有效2头,有效率3.33%;无效3头,无效率5.0%,总有效率95.0%。三个情期受胎率86.67%。对照组治疗20头,治愈15头,治愈率75.0%,显效1头,显效率5.0%;有效2头,有效率10%;无效2头,无效率10%,总有效率90.0%。三个情期受胎率75.0%。可以得出,"清宫助孕液"对奶牛子宫内膜炎具有较好的治疗效果,可以提高情期受胎率。  相似文献   

7.
为了深入了解聚维酮碘凝胶的临床效果,探讨临床用药的最佳方式,本试验选择193头有临床症状的子宫内膜炎患牛,分成以聚维酮碘凝胶处理的治疗组和以金霉素和土霉素处理的对照组。治疗组分三个浓度梯度和两次处理给药。以探讨两因素对治疗效果的影响。结果表明:聚维酮碘凝胶治疗组的有效率和治愈率分别为98.0%和86.3%;金霉素对照组分别为66.1%和33.9%;土霉素对照组分别为71.9%和31.2%。治疗组与两个对照组差异显著(P<0.05)。通过对治疗组内各剂量处理结果进行分析,筛选出了临床用药的最佳剂量和方式,即子宫灌注100 mL聚维酮碘凝胶,隔天一次,连用2次,对于不同病情的子宫内膜炎都能达到较好的治愈效果。  相似文献   

8.
以双黄连灌注液和澳富龙(10%土霉素子宫注入剂)为对照药物,通过临床试验观察促孕灌注液对奶牛子宫内膜炎、产后胎衣不下和屡配不孕的防治作用。选取子宫内膜炎、胎衣不下和屡配不孕自然发病的奶牛随机分组,按照100mL/d的用量给药,分别以子宫内膜炎痊愈、胎衣排出和受胎率为指标对比促孕灌注液、双黄连灌注液和澳富龙对三种疾病的治疗效果。结果表明,促孕灌注液和双黄连灌注液连续使用3d对轻度子宫内膜炎的有效率分别为94.4%和100%,对胎衣不下的有效率均为100%;连续使用4d对重度子宫内膜炎的有效率分别为70.0%和75.0%,澳富龙对重度子宫内膜炎和胎衣不下的有效率分别为100%和50.0%。促孕灌注液和双黄连灌注液均可作为治疗奶牛子宫内膜炎和胎衣不下的有效药物。  相似文献   

9.
宫炎清灌注液治疗奶牛子宫内膜炎临床试验   总被引:1,自引:0,他引:1  
考察宫炎清灌注液治疗奶牛子宫内膜炎临床疗效。方法:选取临床上已发生子宫内膜炎的奶牛,将宫炎清灌注液加温至37℃左右,进行子宫灌注,100ml/次,隔日一次,四次为一个疗程。结果:宫炎清灌注液对奶牛子宫内膜炎的治疗其有效率为100%,治愈率为85.7%。  相似文献   

10.
通过临床试验,观察促孕灌注液对奶牛子宫内膜炎、产后胎衣不下和不孕症的治疗效果。选取子宫内膜炎、胎衣不下和不孕症自然发病的奶牛随机分组,以双黄连灌注液为对照药物,按照100m L/次的用量给药,分别以子宫内膜炎痊愈、胎衣排出和受胎率为指标对比促孕灌注液、双黄连灌注液对三种疾病的治疗效果。结果显示,促孕灌注液和双黄连灌注液连续使用3d对轻度子宫内膜炎和胎衣不下的有效率均为100%,连续使用3~7d对重度子宫内膜炎的有效率为100%。对于不孕症的治疗效果,因持久黄体导致不孕的用药后受胎率达到70%~80%,因屡配不孕导致的用药后受胎率达到70%。可以得出,促孕灌注液和双黄连灌注液均可作为治疗奶牛子宫内膜炎和胎衣不下的有效药物,对治疗因持久黄体和屡配不孕导致的不孕症也有很好的疗效。  相似文献   

11.
1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) is an alkylating agent in the nitrosourea subclass. A prospective evaluation of CCNU was done to determine the maximally tolerated dosage of CCNU in tumor-bearing cats. Response data were obtained when available. Twenty-five cats were treated with CCNU at a dosage of 50-60 mg/m3 body surface area. Complete hematologic data were available for 13 cats. Neutropenia was the acute dose-limiting toxicity. The median neutrophil count at the nadir was 1,000 cells/microL (mean, 2,433 cells/microL; range, 0-9,694 cells/microL). The time of neutrophil nadir was variable, occurring 7-28 days after treatment, and counts sometimes did not return to normal for up to 14 days after the nadir. Based on these findings, a 6-week dosing interval and weekly hematologic monitoring after the 1st treatment with CCNU are recommended. The nadir of the platelet count may occur 14-21 days after treatment. The median platelet count at the nadir was 43,500 cells/microL. No gastrointestinal, renal, or hepatic toxicities were observed after a single CCNU treatment, and additional studies to evaluate the potential for cumulative toxicity should be performed. Five cats with lymphoma and 1 cat with mast cell tumor had measurable responses to CCNU. Phase II studies to evaluate antitumor activity should be completed with a dosing regimen of 50-60 mg/m3 every 6 weeks.  相似文献   

12.
Human and equine athletes are reported to have a high prevalence of gastric disease, and anecdotal evidence suggests a similar phenomenon applies to racing sled dogs. To investigate the prevalence of gastric disease in racing sled dogs, we conducted 2 gastroscopy studies on dogs competing in the annual Iditarod Sled Dog Race. A pilot study of dogs that were either dropped from the 2000 Iditarod Sled Dog Race because of illness or that finished the race indicated that, approximately 5 days after competing, 10 of 28 dogs (35%) had endoscopic evidence of gastric ulceration, erosion, or hemorrhage. The next year, an endoscopic study of 73 dogs participating in the 2001 Iditarod race was performed in order to evaluate a larger population of dogs. Data from 70 of these dogs could be used; 34 (48.5%) had ulceration, erosion, gastric hemorrhage, or some combination of these findings. When this group of 70 dogs was compared retrospectively to a control group of 87 dogs presented to the Texas A&M University (TAMU) Veterinary Medical Teaching Hospital, the Iditarod sled dogs had a significantly higher prevalence (P = .049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large.  相似文献   

13.
Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically significant difference in urine volume over 24 hours between methods; however, urine volume was significantly greater after CRI compared with IA during the first 8 hours ([median 25th percentile, 75th percentile]: 9.6 L [8.9, 14.4] for CRI versus 5.9 L [5.3, 6.0] for IA). CRI produced a more uniform urine flow, decreased fluctuations in plasma volume, and suppressed renal concentrating ability throughout the infusion period. Potassium, Ca, and Cl excretion was greater during CRI than IA (1,133 mmol [1.110, 1,229] versus 764 mmol [709, 904], 102.7 mmol [96.0, 117.2] versus 73.3 mmol [65.0, 73.5], and 1,776 mmol [1,657, 2.378] versus 1,596 mmol [1,457, 1,767], respectively). Elimination half-lives of furosemide were 1.35 and 0.47 hours for CRI and IA, respectively. The area under the excretion rate curve was 1,285.7 and 184.2 mL x mg/mL for CRI and IA, respectively. Furosemide CRI (0.12 mg/kg/h) for 8 hours, preceded by a loading dose (0.12 mg/kg), is recommended when profound diuresis is needed acutely in horses.  相似文献   

14.
The epidemiology of H. placei and of other gastrointestinal nematodes in yearling dairy cattle was examined on two farms in Kiambu District, central Kenya during each of 13 one-month periods from April 1993 to April 1994. On each farm, 32 newly weaned dairy calves were given a single dose of albendazole and then placed on experimental pastures. Twelve of the animals were designated for bi-monthly slaughter (n = 2) and analysis of worm population characteristics and 20 were designated for blood and faecal collection and for weighing. Two parasite-free tracer calves were grazed alongside the weaner calves each month throughout the study period and were also slaughtered for analysis of worm populations. Faecal egg counts, haematological and serum pepsinogen determinations, herbage larval counts, and animal live weight changes were recorded monthly. The study revealed that Haemonchus placei, Trichostrongylus axei, Cooperia spp. and Oesophagostomum radiatum were responsible for parasitic gastroenteritis and that H. placei was the predominant nematode present in the young cattle on both farms. Faecal egg counts from resident cattle and necropsy worm counts revealed that pasture larval levels were directly related to the amount of rainfall. The total worm burdens in the animals were highest during the rainy season (March–June and October–December) and lowest during the dry seasons (July–September and January–February). The very low recovery of immature larvae of H. placei from the tracer calves indicated that arrested development is not a feature of the life cycle of this parasite in central Kenya. The maintenance of the parasite population depended on continuous cycling of infection between the host and the pasture. The agroclimatic conditions of the study area were such that, in general, favourable weather conditions for the development and survival of the free-living stages of gastrointestinal nematodes existed all year round.  相似文献   

15.
The occurrence of ectoparasites in sheep flocks is frequently reported but seldom quantified. Sheep production used to be a predominantly family activity in the state of Sa~o Paulo (Brazil), but it began to become a commercial activity in the past decade. Thus, information about the ectoparasites existing in sheep flocks has become necessary. The present data were obtained by means of questionnaires sent to all sheep breeders belonging to the `Associaça~o Paulista de Criadores de Ovinos' (ASPACO; Sa~o Paulo State Association of Sheep Breeders). Response reliability was tested by means of random visits paid to 10.6% of the respondents. Most of the properties (89.5%) reported the presence of one or more ectoparasites. Screw-worm (Cochliomyia hominivorax) was the most frequent ectoparasite (72.5%), followed by bot fly larvae (Dermatobia hominis, 45.0%), ticks (Amblyomma cajennense) and Boophilus microplus, 31.3%) and finally lice (Damalinia ovis, 13.8%). Combined infestations also occurred, the most common one being screw-worm with bot fly larvae (36.0%) followed by bot fly larvae with ticks (13.9%), screw-worm with ticks (9.3%), bot fly larvae with lice (6.9%), and ticks with lice (5.0%). The most common triple combination was screw-worm, bot fly larvae and ticks (12.8%). Breeds raised for meat or wool were attacked by bot fly larvae and ticks more often than other breeds. Lice were only absent from animals of indigenous breeds. The relationships among these ectoparasites are discussed in terms of sheep breeds, flock size, seasonality and the ectoparasitic combinations on the host.  相似文献   

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17.
An experiment was conducted to study disappearance of C14 to C18 fatty acids, lag times and biohydrogenation (BH) rates of C18 fatty acids of ground soya bean and canola seeds in situ. Three ruminally fistulated Dallagh sheep were used to determine ruminal BH of unsaturated fatty acids (UFAs). Differences in the disappearance of fatty acids through the bags and lag times were observed between the oilseeds. We saw that the longer the incubation time of the oilseeds in the rumen, the lower the content of C18:2 and C18:3. Significantly higher lag times for both C18:2 and C18:3 were observed in ground canola compared to ground soya bean. BH rates of C18:2 and C18:3 fatty acids in soya bean were three times higher than those of canola. These results suggest that the fatty acid profile of fat source can affect the BH of UFAs by rumen micro‐organisms. So that UFAs of canola had higher ability to escape from ruminal BH. It seems that fatty acid profile of ruminant products is more affected by canola seed compared to soya bean seed.  相似文献   

18.
Serum biochemical values and the wet weight to dry weight ratios of tissues were determined in yaks in Shandan county of Gansu province. The liver, kidney, heart and muscle contents of seven elements in yaks were also analysed. Most serum biochemical values were similar to those of cattle, camels and sheep, but the calcium concentration was considerably above the normal range for other ruminants. The liver contained the highest concentrations of copper, manganese and cobalt and the kidney of selenium, iron and calcium.Abbreviations Alb albumin - ALT alanine aminotransferase - AST aspartate aminotransferase - BUN blood urea nitrogen - Chol cholesterol - Glob globulin - -GT -glutamyl transpeptidase - IP inorganic phosphorus - TP total protein  相似文献   

19.
正We are pleased to publish the second special issue on avian brood parasitism and to be responsible guest editors for the two special issues of Chinese Birds (Vol. 3, No. 4, 2012 and Vol. 4, No. 1, 2013), entitled "Avian Brood Parasitism - A Growing Research Area in Behavioral Ecology". The first issue was published in December 2012. The goal of the two special issues is to publish accumulated knowledge and some of the recent developments in  相似文献   

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