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1.
牛病毒性腹泻病毒(Boyine viral diarrhoea virus,BVDV)在我国发现有20多年,而在世界范围来讲已有近100年的历史.由于牛病毒性腹泻病毒造成奶牛生产性能下降、繁殖障碍、持续感染等,是导致集约化奶牛场严重亏损的重要原因.且牛病毒性腹泻导致的黏膜病致死率几乎100%,已经严重阻碍养牛业的发展,但目前我国对牛病毒性腹泻还没有好的防控措施.文章对牛病毒性腹泻的发生历史总结,便于在牛病毒性腹泻病毒的诊断和预防中参考.  相似文献   

2.
<正>牛病毒性腹泻的病原体是牛病毒性腹泻病毒(BVDV),病毒不仅可导致牛出现病毒性腹泻,同时,还会导致猪、羊等出现病毒性腹泻。牛在出现病毒性腹泻之后,比较容易出现腹泻、出血综合征、流产、肺炎等持续恶性感染的临床症状。我国首次发现该病是在20世纪80年代,是从国外引进的奶牛以及绵羊体内分离。随着我国养殖业的不断发展,牛病毒性腹泻对养殖业的影响也越来越严重。有研究表明,牛病毒性腹泻的情况不断加重,且  相似文献   

3.
牛病毒性腹泻的发病机理与诊治   总被引:5,自引:1,他引:4  
牛病毒性腹泻病毒是造成奶牛生产性能下降、繁殖障碍、持续感染等的一个主要原因,并能给养牛业造成严重的经济损失.牛病毒性腹泻导致的黏膜病致死率几乎为100%,严重阻碍了养牛业的发展,但目前我国对牛病毒性腹泻还没有好的防控措施.笔者对牛病毒性腹泻的发病机理、临床症状及诊治作了综述,便于在牛病毒性腹泻病的诊断和预防中参考.  相似文献   

4.
<正>1流行特点牛病毒性呼吸道疾病会导致牛出现严重的呼吸道症状,发生混合感染,死亡率增加。常见的病毒性呼吸道疾病有:牛传染性鼻气管炎,致病病毒为牛传染性鼻气管炎病毒(IBRV);犊牛病毒性肺炎,致病病毒为牛呼吸道合胞体病毒(BRSV);牛病毒性腹泻,致病病毒为牛病毒性腹泻病毒(BVDV);牛副流感,致病病毒为牛副流感病毒(BPIV)。牛病毒性呼吸道疾病秋冬、冬春交替时期较为流行。病毒能通过口腔、鼻腔、眼部分泌物,  相似文献   

5.
正犊牛病毒性腹泻是由牛病毒性腹泻病毒引起的一种养牛场常见而多发的传染病,也称黏膜病,我国将其列为二类传染病,以犊牛多发。犊牛病毒性腹泻分布广泛,全世界范围内均有发生。该病以发热、腹泻、脱水、流产等为主要临床症状,常呈持续性感染状态。犊牛病毒性腹泻严重危害养牛业的稳定生产,对世界各地的牛养殖业造成了巨大的经济损失。1流行特点牛病毒性腹泻在呈世界范围内分布,尤以养牛业发达的国家和地区最为严重。我国牛病毒性腹泻从上世纪80年代  相似文献   

6.
牛病毒性腹泻又称牛黏膜病,是由牛病毒性腹泻病毒引起的一种主要以黏膜发炎、糜烂、坏死、发热和腹泻为特征,发生于牛的热性传染病.由于牛病毒性腹泻分布广泛,流行性严重,是我国乃至国际贸易中一种重要的牛的传染病之一,严重危害我国养牛业的健康可持续发展,造成养牛业巨大的经济损失.为有效的防治牛病毒性腹泻,本文从流行病学、临床变化...  相似文献   

7.
本研究旨在了解宁夏地区肉牛病毒性腹泻病原感染现状及流行特点,为牛腹泻病的防控工作提供科学依据。本研究采用RT-PCR方法对宁夏地区293份肉牛拭子样本进行牛病毒性腹泻病毒(BVDV)、牛冠状病毒(BCoV)、牛轮状病毒(BRV)、牛诺瓦病毒(BNoV)、牛星状病毒(BAstV)检测,并对其进行遗传进化分析。研究表明,该地区肉牛普遍存在腹泻病毒的感染及混合感染;散养模式下肉牛腹泻病毒的感染及混合感染情况较规模化养殖严重;病毒性腹泻在不同地区、不同病毒差异明显;遗传进化分析发现宁夏地区BVDV流行株为1e亚型,BRV流行株为G1亚型,BNoV流行株为GⅢ.2亚型,BCoV流行株与法国株遗传进化关系较近。结果显示,宁夏地区肉牛普遍存在腹泻相关病毒的感染,不同养殖模式、不同地区、不同病毒之间存在差异,且混合感染严重。  相似文献   

8.
牛病毒性腹泻的发病机理与诊治   总被引:1,自引:0,他引:1  
牛病毒性腹泻是造成奶牛生产性能下降、繁殖障碍、持续感染等的一个主要原因,并能给养牛业造成严重的经济损失。牛病毒性腹泻导致的黏膜病致死率几乎为100%,严重阻碍了养牛业的发展,但目前我国对牛病毒性腹泻还没有很好的防控措施。笔者对牛病毒性腹泻的发病机理、临床症状及诊治作一综述,便于同行在牛病毒性腹泻病的诊断和预防中予以参考。  相似文献   

9.
牛病毒性腹泻黏膜病由牛病毒性腹泻黏膜病病毒引起,该病普遍存在于世界各地的牛群中,给养牛业带来的主要影响有腹泻、黏膜病、持续感染、免疫抑制等,并伴随严重的经济损失。本文综述了该病疫苗在国内外使用情况及研究进展,为我国牛病毒性腹泻黏膜病疫苗研究提供依据。  相似文献   

10.
牛病毒性腹泻/黏膜病简称病毒性腹泻或黏膜病,1946年由Olafson等在纽约首次发现,牛病毒性腹泻病(BVD)是由牛病毒性腹泻病毒引起的牛传染病,其特征是急性糜烂性口炎、消化道黏膜糜烂坏死、胃肠炎和腹泻。在多数牛群中感染率高,但临床发病率低。本病呈全球性分布,各养牛业发达国家均有流行。我国存在着严重的污染。  相似文献   

11.
试验选用96头平均体重14.82 kg左右的杜×长×大断奶仔猪,随机分成4组,每组3栏,每栏8头(公母各半)。对照组饲喂基础日粮,试验1、2、3组分别添加1%80目白术、0.2%白术多糖和1%微米白术。试验期30 d。结果表明:在生长性能方面,与对照组相比,1%微米白术添加组可显著提高日增重(P0.05)、降低饲料增重比和腹泻率,而且效果优于1%80目白术组和0.2%白术多糖组,在肠道形态和肠道微生态区系方面,与对照组相比,日粮添加1%80目白术、0.2%白术多糖、1%微米白术均可不同程度的提高十二指肠和空肠的绒毛高度,加深十二指肠和空肠的隐窝深度,并且增加肠道微生态区系的多样性,其中以1%微米白术添加组的效果最佳。  相似文献   

12.
Sissay, M.M., Uggla, A. and Waller, P.J., XXXX. Prevalence and seasonal incidence of nematode parasites and fluke infections of sheep and goats in eastern Ethiopia. Tropical Animal Health and Production, XXXX. A 2-year abattoir survey was carried out to determine the prevalence, abundance and seasonal incidence of gastro-intestinal (GI) nematodes and trematodes (flukes) of sheep and goats in the semi-arid zone of eastern Ethiopia. During May 2003 to April 2005, viscera including liver, lungs and GI tracts were collected from 655 sheep and 632 goats slaughtered at 4 abattoirs located in the towns of Haramaya, Harar, Dire Dawa and Jijiga in eastern Ethiopia. All animals were raised in the farming areas located within the community boundaries for each town. Collected materials were transported within 24 h to the parasitology laboratory of Haramaya University for immediate processing. Thirteen species belonging to 9 genera of GI nematodes (Haemonchus contortus, Trichostrongylus axei, T. colubriformis, T. vitrinus, Nematodirus filicollis, N. spathiger, Oesophagostomum columbianum, O. venulosum, Strongyloides papillosus, Bunostomum trigonocephalum, Trichuris ovis, Cooperia curticei and Chabertia ovina), and 4 species belonging to 3 genera of trematodes (Fasciola hepatica, F. gigantica, Paramphistomum {Calicohoron} microbothrium and Dicrocoelium dendriticum) were recorded in both sheep and goats. All animals in this investigation were infected with multiple species to varying degrees. The mean burdens of adult nematodes were generally moderate in both sheep and goats and showed patterns of seasonal abundance that corresponded with the bi-modal annual rainfall pattern, with highest burdens around the middle of the rainy season. In both sheep and goats there were significant differences in the mean worm burdens and abundance of the different nematode species between the four geographic locations, with worm burdens in the Haramaya and Harar areas greater than those observed in the Dire Dawa and Jijiga locations. Similar seasonal variations were also observed in the prevalence of flukes. But there were no significant differences in the prevalence of each fluke species between the four locations. Overall, the results showed that Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Fasciola and Paramphistomum species were the most abundant helminth parasites of sheep and goats in eastern Ethiopia.  相似文献   

13.
14.
1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) is an alkylating agent in the nitrosourea subclass. A prospective evaluation of CCNU was done to determine the maximally tolerated dosage of CCNU in tumor-bearing cats. Response data were obtained when available. Twenty-five cats were treated with CCNU at a dosage of 50-60 mg/m3 body surface area. Complete hematologic data were available for 13 cats. Neutropenia was the acute dose-limiting toxicity. The median neutrophil count at the nadir was 1,000 cells/microL (mean, 2,433 cells/microL; range, 0-9,694 cells/microL). The time of neutrophil nadir was variable, occurring 7-28 days after treatment, and counts sometimes did not return to normal for up to 14 days after the nadir. Based on these findings, a 6-week dosing interval and weekly hematologic monitoring after the 1st treatment with CCNU are recommended. The nadir of the platelet count may occur 14-21 days after treatment. The median platelet count at the nadir was 43,500 cells/microL. No gastrointestinal, renal, or hepatic toxicities were observed after a single CCNU treatment, and additional studies to evaluate the potential for cumulative toxicity should be performed. Five cats with lymphoma and 1 cat with mast cell tumor had measurable responses to CCNU. Phase II studies to evaluate antitumor activity should be completed with a dosing regimen of 50-60 mg/m3 every 6 weeks.  相似文献   

15.
Our particular attention in this article was given to natural mediators for macrophages isolated from the sites of tissue injury. A number of chemotactic factors, which may satisfy many criteria making them acceptable as inflammatory leucocyte chemotactic factors, has been separated. Among them, our laboratory has isolated three macrophage (monocyte) chemotactic factors (MCF-a, -b and -c). Their purification, characterization and functional specificity are discussed.  相似文献   

16.
Human and equine athletes are reported to have a high prevalence of gastric disease, and anecdotal evidence suggests a similar phenomenon applies to racing sled dogs. To investigate the prevalence of gastric disease in racing sled dogs, we conducted 2 gastroscopy studies on dogs competing in the annual Iditarod Sled Dog Race. A pilot study of dogs that were either dropped from the 2000 Iditarod Sled Dog Race because of illness or that finished the race indicated that, approximately 5 days after competing, 10 of 28 dogs (35%) had endoscopic evidence of gastric ulceration, erosion, or hemorrhage. The next year, an endoscopic study of 73 dogs participating in the 2001 Iditarod race was performed in order to evaluate a larger population of dogs. Data from 70 of these dogs could be used; 34 (48.5%) had ulceration, erosion, gastric hemorrhage, or some combination of these findings. When this group of 70 dogs was compared retrospectively to a control group of 87 dogs presented to the Texas A&M University (TAMU) Veterinary Medical Teaching Hospital, the Iditarod sled dogs had a significantly higher prevalence (P = .049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large.  相似文献   

17.
Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically significant difference in urine volume over 24 hours between methods; however, urine volume was significantly greater after CRI compared with IA during the first 8 hours ([median 25th percentile, 75th percentile]: 9.6 L [8.9, 14.4] for CRI versus 5.9 L [5.3, 6.0] for IA). CRI produced a more uniform urine flow, decreased fluctuations in plasma volume, and suppressed renal concentrating ability throughout the infusion period. Potassium, Ca, and Cl excretion was greater during CRI than IA (1,133 mmol [1.110, 1,229] versus 764 mmol [709, 904], 102.7 mmol [96.0, 117.2] versus 73.3 mmol [65.0, 73.5], and 1,776 mmol [1,657, 2.378] versus 1,596 mmol [1,457, 1,767], respectively). Elimination half-lives of furosemide were 1.35 and 0.47 hours for CRI and IA, respectively. The area under the excretion rate curve was 1,285.7 and 184.2 mL x mg/mL for CRI and IA, respectively. Furosemide CRI (0.12 mg/kg/h) for 8 hours, preceded by a loading dose (0.12 mg/kg), is recommended when profound diuresis is needed acutely in horses.  相似文献   

18.
Genetic variations in chromosome Y are enabling researchers to identify paternal lineages, which are informative for introgressions and migrations. In this study, the male‐specific region markers, sex‐determining region‐Y (SRY), amelogenin (AMELY) and zinc finger (ZFY) were analysed in seven Turkish native goat breeds, Angora, Kilis, Hair, Honaml?, Norduz, Gürcü and Abaza. A SNP in the ZFY gene defined a new haplotype Y2C. All domestic haplogroups originate from Capra aegagrus, while the finding of Y1A, Y1B, Y2A and Y2C in 32, 4, 126 and 2 Turkish domestic goats, respectively, appears to indicate a predomestic origin of the major haplotypes. The occurrence of four haplotypes in the Hair goat and, in contrast, a frequency of 96% of Y1A in the Kilis breed illustrate that Y‐chromosomal variants have a more breed‐dependent distribution than mitochondrial or autosomal DNA. This probably reflects male founder effects, but a role in adaptation cannot be excluded.  相似文献   

19.
The objective of this report was to characterize 20-year changes in proportion of calcium oxalate (CaOx) calculi and struvite calculi in dogs, and associations with breed, age, and sex. In this retrospective study, results of analysis of urinary calculi from dogs were reviewed for specimens received between July 1, 1981, and December 31, 2001. Breed, sex, age, year of submission of the specimen, and mineral type(s) were analyzed statistically. CaOx or Struvite or both were contained in 18,966 of 20,884 (91%) specimens. For both sexes, a 20-year statistically significant increase was observed in the proportion of calculus specimens that contained CaOx. The increase in this proportion was greater in females (1% to 31%) than in males (18% to 82%). From 1998 to 2001, when proportions may have plateaued, the odds of specimens containing CaOx were markedly higher in 18 breeds, markedly lower in 5 breeds, and not significantly different in 13 breeds compared with crossbreds. For both sexes, a 20-year statistically significant decrease was observed in the proportion of calculus specimens that contained struvite. This decrease in proportion was greater for males (79-16%) than for females (97-68%). From 1998 to 2001, when proportions plateaued, the odds of calculi containing struvite were markedly lower in 20 breeds, markedly higher in 1 breed, and not significantly different in 15 breeds when compared with crossbreds. Breed, age, and sex were associated statistically with CaOx or struvite urolithiasis. In conclusion, there appears to have been a long-term increase in the proportion of specimens of canine urinary calculi that contain CaOx as well as a long-term decrease in the proportion of specimens of calculi that contain struvite for both male and female dogs. The rate of change appeared to begin leveling off in the period 1998 to 2001. The recent proportion of dogs with either CaOx- or struvite-associated urolithiasis may depend on breed, age, and sex, and on interactions among these 3 factors.  相似文献   

20.
<正>1.INTRODUCTION Ensuring transportation network security is one Of the most daunting challenges confronting homeland security agencies today.Significant research has been dedicated.To model and analyze the vulnerability of transportation systems,while notably fewer studies propose specific strategies for deploying defensive technologies to safeguard these systems.  相似文献   

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