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地塞米松是一种长效糖皮质激素,其衍生物有氢化可地松、泼尼松等,具有是抗炎症、抗免疫、抗休克、抗毒素的作用,是临床上常用的药物之一。正确认识它的作用及禁忌,对于临床用药具有重要意义。 相似文献
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化学药物气雾免疫法是指借助雾化器使药物成为雾状,通过畜禽肺部吸收来治疗畜禽疾病的一种新方法。此法疗效快,而且省时、省力。一、气雾免疫疗法的常用药物及方法一般来说,可供注射的,能被畜禽肺部吸收而又无不良刺激的药物,均可采用气雾免疫法。目前,常用的药物有... 相似文献
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鸡球虫病是由一种或多种球虫寄生于鸡肠道黏膜上皮细胞内引起的一种急性流行性原虫病。本病分布广泛,在养鸡场是一种多发病,给养鸡业造成巨大损失。为了彻底解决药物防治所带来的日益严重的抗药性及药物残留问题,人们已逐渐重视球虫病的免疫防制策略。近年来,国内许多集约化养殖场已经开始应用球虫病疫苗。笔者结合自己的经验,谈一下球虫病疫苗的拌料免疫方法及注意事项。 相似文献
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免疫是机体识别自身物质和排除非自身物质的一种保护性生理反应.具有维持自身稳定,防止传染和免疫监视的作用。所以说免疫系统是生命的卫士.是机体的防御系统.它包括免疫器官、免疫细胞和免疫分子。机体免疫力的高低直接影响其抗病力和生产力。目前临床上应用的免疫调节剂多为一些化学药物,有些药物残留量大,既危害人类健康,又污染环境。因此,寻找安全可靠、无药物残留、用药浓度小、 相似文献
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荷兰科学家采用遗传工程技术 ,成功地培育出一种能从所产的牛乳中获得免疫药物的药用牛 ,并计划开办用这种牛的牛乳制药的制药厂 ,大量生产免疫药品。该药用牛是这样培育成功的 :先将人体所具有的乳铁蛋白质组成的遗传因子 ,植入牛的受精卵中 ,培育成一种名叫“海尔曼”的具有这种基因的公牛 ,然后再用“海尔曼”公牛的精液给母牛授精。母牛所产下的新一代母牛 ,牛乳中会含有此类基因的物质 ,可以用来制造免疫药物。研究证实 ,乳铁蛋白是一种可以用来抑制细菌的药物 ,能用于治疗免疫力衰退的患者 ,如果利用药用牛的乳汁制取 ,不仅原料丰富 ,… 相似文献
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沙门氏菌是一种具有侵袭性的传染性人兽共患病原菌。抗生素防治沙门氏菌病有一定的效果,但不能完全防止细菌感染,并且长期使用存在耐药性与药物残留等诸多问题。疫苗是降低畜禽病原感染的重要手段,但传统疫苗在免疫效力、安全性等方面存在一定问题。细菌菌蜕是一种只含有细菌内外膜完整结构的死菌体,但保留了完整细胞表面结构及成分,具有良好的免疫原性,相较于传统疫苗,菌蜕疫苗能刺激机体产生高水平的体液免疫、细胞免疫以及黏膜免疫,表现出更好的保护力。文章综述了沙门氏菌菌蜕的研究进展,总结了不同血清型沙门氏菌菌蜕作为灭活疫苗、抗原载体、药物载体和佐剂等方面的应用,为沙门氏菌病新型疫苗的开发提供科学参考。 相似文献
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该文就人工合成药和中草药对白细胞、单核一巨噬细胞系统、细胞免疫、体液免疫及细胞因子的促进作用进行了综述。药物对细胞的免疫促进作用主要是通过提高免疫细胞的数量和功能,药物对体液免疫的促进作用主要是通过刺激机体产生较高滴度的抗全和延长抗体的产生时间;药物对细胞因子的促进作用主要是促进具有调节机体免疫功能的细胞因子的产生。 相似文献
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一 磺胺类药物的作用
1防外源性的杆菌感染
如巴氏杆菌、痢疾杆菌、沙门氏杆菌、大肠杆菌引起的呼吸道肠道感染、拉稀、痢疾腹泻等。鸡食欲不振、发烧、拉稀的都可以用磺胺片拌料,每千克侗料加0.5克×2片,连吃4天就可控制病情。 相似文献
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Neidert E Saschenbrecker PW Patterson JR Fesser A 《The Canadian veterinary journal. La revue veterinaire canadienne》1985,26(9):282-284
Sulfonamide residues in the livers of wholesome carcasses of Canadian pork were monitored over the six year period ending March 31, 1985. The annual rate of violative residues decreased from 9.92% to 2.75% over the course of the six years. At present the incidence of violation in the livers is 2.35% and there is no significant difference within the various regions of Canada. This would result in a muscle violative rate of 0.8%.
The only sulfonamide found at violative levels was sulfamethazine. All violative samples were within the range 0.11-4.00 ppm. Over the period of the survey the incidence of violations at all levels decreased. Violations at higher levels decreased most rapidly resulting in a continuous reduction of the mean level in violative samples.
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E Kokue M Shimoda R Suzuki 《Nippon juigaku zasshi. The Japanese journal of veterinary science》1989,51(3):485-490
The influence of ingested volume of a sulfa drug suspension, sodium sulfamonomethoxine (SMMNa), on the oral pharmacokinetics was studied in pigs, with regard to bioavailability and gastric emptying. Eighteen pigs, weighing 30-70 kg, were used. Phenol red solution was used for the evaluation of gastric emptying study. SMMNa suspension was used for pharmacokinetic study. Both of these fluids were administered by natural swallowing. Three experimental groups were constructed: G-I; 5 ml/kg of the test fluids to starved animals, G-II; 5 ml/kg of the test fluids to fed animals and G-III; 20 ml/kg of the fluids to fed animals. The glucose glycine electrolyte solution (GGES) was used as the vehicle for both the compounds. Six pigs, having duodenal cannula, were used for the study of gastric emptying. The gastric emptying rate was rapid in G-I, relatively rapid in G-III, and slow and variable in G-II. In agreement with the result of gastric emptying study, the values of Cmax and tmax were high and rapid in G-I, relatively high and rapid in G-III, and low and slow in G-II. Accordingly, the voluminous ingestion of drug suspension can facilitate the gastric emptying, in turn may make the oral absorption of the drug rapid-and-uniform. The 20 ml/kg volume of sulfa drug suspension may practically be recommended for the oral administration in pigs. 相似文献
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本文概述了猪的毛色类型、猪的毛色遗传模式,着重综述了猪毛色基因分子基础的研究进展,指出存在问题并就未来发展方向做了思考。 相似文献
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魏静 《四川畜牧兽医学院学报》2009,(4):28-32
在现代法律秩序中,商会自治规范是制定法的基础和必要的补充,甚至在某些方面替代了制定法;商会自治规范主要包括商会组织规范、行为规范、惩罚规范以及争端解决规范等;其效力仅及于其内部成员;商会自治规范和制定法之间存在冲突,但也存在整合的基础。 相似文献
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以国际标准强毒R株人工感染非免疫产蛋鸡,定时扑杀,分别从鼻窦、眶下孔、气管、肺、气囊、卵巢和输卵管分离MG,并收集感染鸡所产蛋分离MG。结果表明,人工感染48小时后上、下呼吸道及肺已被全面感染,96小时气囊已被感染,120小时输卵管已能分离到MG,卵巢始终分离不到MG。人工感染鸡自144小时便能在其所产蛋中分离出MG。药物治疗能在72小时内消除感染,油乳剂苗则需24天后逐渐降低蛋内MG分离率,药物卵内注射、种蛋药浴、高温处理均能杀死卵内MG,但以研制的种蛋浸泡剂药浴效果为最好。 相似文献
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Effects of size of ingestively masticated fragments of plant tissues on kinetics of digestion of NDF
Ingestively masticated fragments were collected and sized via sieving. Different sizes of esophageal masticate and ruminal digesta fragments, and ground fragments of larger masticated pieces were incubated in vitro, and undigested NDF remaining at intervals of up to 168 h of incubation was determined. The ruminal age-dependent time delay (tau) for onset of digestion of NDF was positively correlated (P < 0.004) with the mean sieve aperture estimated to retain 50% of the fragments between successive sieve apertures (MRA). Degradation rate of potentially degradable NDF (PDF) and level of indigestible NDF were not related (P > 0.10) to MRA of masticated and ground fragments. Estimates of tau were positively related to MRA, with slopes of bermudagrass < corn silage < ruminal fragments of corn silage. It was concluded that fragment size-, and consequently, ruminal age-dependent onset of PDF degradation of a mixture of different fragment sizes results in an age-dependent rate of degradation of the more rapidly degrading of two subentities of PDF. Models are proposed that assume a tau before onset of simultaneous degradation of PDF from two pools characterized as having gamma-modeled age-dependency and age-constant rates. The ruminal age-dependent pool seems to be associated with the faster-degrading pool, and its rate parameter increases with range in MRA in the population of fragments. Conceptually, the ruminal age-dependent rate parameter for PDF degradation seems to represent a composite of several effects: 1) effects of the size-dependent tau; 2) range in MRA of the population of ingestively masticated fragments; and 3) subentities of PDF that degrade via more rapid age-dependent rates compared with subentities of PDF that degrade via age-constant rates. The estimated fractional rates of ruminative comminution of ingestively masticated fragments (0.060 to 0.075/h) were of a magnitude similar to the mean fractional rates of PDF digestion (0.030 to 0.085/h), which implies that ruminative comminution may be first-limiting to fractional rate of PDF digestion. The in vivo roles of ingestive and ruminative mastication of fragments on PDF degradation must be considered in any kinetic system for estimating PDF digestion in the rumen. These results and others in the literature suggest that the rate of surface area exposure rather than intrinsic chemical attributes of PDF may be first-limiting to degradation rate of PDF in vivo. 相似文献