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1.
纳米硒对肉鸡组织硒含量和谷胱甘肽过氧化物酶活性的影响   总被引:10,自引:0,他引:10  
本试验采用2×6因子完全随机设计,研究了纳米硒和亚硒酸钠2种硒源对肉鸡组织硒含量和谷胱甘肽过氧化物酶(GSH-Px)活性的影响。岭南黄公母混合雏780羽按饲养试验要求分为13组,每组4个重复,每个重复15羽。将纳米硒和亚硒酸钠2种硒源分别以0.1、0.2、0.3、0.4、0.5、1.0mg/kg6个硒水平添加到基础日粮中,配制成12种试验日粮,基础日粮作对照。结果显示:(1)亚硒酸钠添加浓度在0.2~0.4mg/kg硒添加水平范围内肉鸡生长性能和GSH-Px活性处于高峰平台,1.0mg/kg硒添加水平肉鸡生长性能和GSH-Px活性显著低于0.2~0.4mg/kg硒添加水平。纳米硒添加浓度在1.0mg/kg肉鸡生长性能和GSH-Px活性仍然保持在高峰平台。(2)硒源添加浓度在0.1~0.3mg/kg时,亚硒酸钠和纳米硒对肉鸡生长性能的影响无显著差异(P>0.05);硒源添加浓度在0.4~1.0mg/kg时,纳米硒组肉鸡生长性能显著高于亚硒酸钠组(P<0.05)。(3)硒源添加浓度在0.1~0.4mg/kg时,两种硒源对GSH-Px活性的影响无显著差异(P>0.05);在0.5和1.0mg/kg硒添加水平上,纳米硒组GSH-Px活性显著高于亚硒酸钠组(P<0.05)。(4)不加硒的空白组全血和组织硒含量显著低于硒添加组。在同一硒添加水平上,纳米硒组和亚硒酸钠组肉鸡全血硒浓度差异不显著,但是,组织硒含量却受硒源的影响。硒源添加  相似文献   

2.
本试验旨在考察不同硒源及硒水平对大鼠生长性能、血清抗氧化能力及组织硒沉积的影响,并以亚硒酸钠和商品酵母硒(酵母硒B)为参比,对本课题组用糖蜜和尿素为发酵底物研制的酵母硒(酵母硒A)生物学效价进行评定.将硒耗竭2周后的70只8周龄左右Wistar雌性大鼠称重,随机分到10个处理,每个处理7个重复,每个重复1只大鼠,分别饲喂不同处理的饲粮21d.处理1不添加任何形式的硒源,处理2~9在基础饲粮中分别以亚硒酸钠或酵母硒A的形式添加0.1、0.2、0.3和0.4mg/kg硒,处理10以酵母硒B形式添加0.3mg/kg硒.结果表明:1)不同硒源及硒水平对大鼠生长性能、血清谷胱甘肽过氧化物酶(GSH-Px)和超氧化物歧化酶活性影响不显著(P>0.05);2)组织硒含量随饲粮硒水平的升高极显著增加(P<0.01),添加酵母硒A组大鼠组织硒含量显著高于亚硒酸钠组(P<0.05);3)以亚硒酸钠为参比,血清GSH-Px活性及肝脏、肾脏和肌肉硒含量作为判定指标,酵母硒A的相对生物学效价分别为95.9%、127.5%、114.5%和101.2%;4)添加酵母硒A和酵母硒B对大鼠生长性能、血清抗氧化能力的影响不显著(P>0.05),但添加酵母硒A组大鼠肾脏硒含量极显著高于酵母硒B组(P<0.01),而酵母硒B在肌肉中有更多的硒沉积(P<0.01).结果提示:1)硒源对大鼠组织硒沉积有较大影响,酵母硒相对于亚硒酸钠具有更高的生物学效价,但不同酵母硒之间存在一定的差异;2)饲粮硒水平对大鼠血清抗氧化能力影响较小,以血清GSH-Px活性为衡量标准,0.1mg/kg硒的酵母硒和亚硒酸钠都能满足大鼠的需要,但更高水平的酵母硒可以使大鼠组织中有更多硒的储备.  相似文献   

3.
本试验旨在研究硒源和硒水平对军曹鱼幼鱼生长性能、肝脏和血清抗氧化指标及组织硒含量的影响,以确定军曹鱼幼鱼对不同硒源的最适需要量。在基础饲料中分别添加0(对照)、0.3、0.6、0.9和1.2 mg/kg(以硒计)的亚硒酸钠(Se-S)或蛋氨酸硒(Se-Met),配制9种试验饲料(共用对照饲料),饱食投喂初始体重为(22.18±0.35)g的军曹鱼幼鱼10周。每种试验饲料投喂3个网箱(重复),每个网箱放养30尾试验鱼。结果表明:1)硒水平对特定生长率(SGR)和增重率(WGR)有极显著影响(P0.01),但对成活率(SR)和饲料系数(FCR)无显著影响(P0.05);硒源及硒源与硒水平的交互作用对SGR、W GR、FCR和SR均无显著影响(P0.05)。SGR和W GR随着硒水平的升高先升高后降低。2)硒水平极显著影响肝脏谷胱甘肽过氧化物酶(GSH-Px)、谷胱甘肽还原酶(GR)活性和丙二醛(MDA)含量及血清GSH-Px活性(P0.01),并显著影响血清GR活性(P0.05);硒源极显著影响肝脏GR、总超氧化物歧化酶(T-SOD)、过氧化氢酶(CAT)活性和MDA含量及血清T-SOD活性(P0.01);硒源和硒水平的交互作用显著影响肝脏CAT活性和MDA含量及血清T-SOD活性(P0.05)。肝脏和血清GSH-Px活性随着硒水平的升高呈先升高后稳定趋势,GR活性呈先下降后稳定趋势。2种硒源均在添加量为0.9 mg/kg时有最高的肝脏GSH-Px活性,最低的肝脏GR活性。肝脏CAT活性随着硒水平的升高逐渐升高。3)脊椎骨、全鱼和肝脏硒含量随硒水平的升高而增加。硒源极显著影响脊椎骨硒含量(P0.01),硒源和硒水平的交互作用极显著影响肝脏和脊椎骨硒含量(P0.01)。以蛋氨酸硒和亚硒酸钠为硒源,通过二次回归曲线分析得出饲料硒水平分别为1.29和1.46 mg/kg时军曹鱼幼鱼可以获得最大SGR。以SGR和全鱼硒含量为判据,军曹鱼幼鱼对蛋氨酸硒的生物利用率分别相当于亚硒酸钠的1.20和2.90倍。  相似文献   

4.
不同硒源对蛋鸡组织硒含量及其抗氧化能力的影响   总被引:1,自引:0,他引:1  
本试验比较研究了富硒益生菌(Selenium-enriched probiotics,SP)和亚硒酸钠(Sodium selenite,SS)对蛋鸡肝脏、肾脏和心肌硒含量及其抗氧化能力的影响。选取800羽健康罗曼蛋鸡,随机均分为8组,将2硒源分别以3个硒水平(0.2、0.5和1.0mg·kg-1)添加到基础日粮中组成6种试验日粮,同时将益生菌添加到基础日粮中作为益生菌对照,基础日粮作为空白对照,进行为期28d的饲养试验。在试验结束时,杀鸡取肝脏、肾脏和心肌分别进行硒含量及其谷胱甘肽过氧化物酶(GSH-Px)活性、过氧化氢酶(CAT)活性、超氧化物歧化酶(SOD)活性和总抗氧化能力(T-AOC)的测定。结果表明,补硒能提高蛋鸡肝脏、肾脏、心肌的硒含量以及GSH-Px、CAT、SOD的活性和T-AOC(P0.05);且随着硒添加水平的升高,肝脏、肾脏和心肌的硒含量、GSH-Px活性均有显著升高(P0.05);添加SP在提高肝脏和心肌硒含量的能力上和在提高肝脏、肾脏和心肌的GSH-Px活性、CAT活性以及肾脏的SOD活性和T-AOC的能力上要优于或显著优于SS。结果提示,补充硒能提高蛋鸡组织硒含量及其抗氧化能力,特别提倡添加低中水平(0.2和0.5mg·kg-1)SP源硒。  相似文献   

5.
试验旨在研究日粮硒水平对4~6月龄绒山羊生长性能和组织抗氧化能力的影响,为确定绒山羊羔羊日粮中适宜的硒供给量提供依据。选用体况良好、体重接近的4月龄陕北白绒山羊羯羔羊24只,采用单因子随机区组设计分为4组,分别饲喂硒含量为0.11、0.21、0.41、0.61 mg/kg的4种试验日粮,试验期为60 d。结果表明:日粮硒水平对绒山羊羔羊平均日增重无显著影响(P>0.05)。肝脏和肌肉中的硒含量以及谷胱甘肽过氧化物酶(GSH-Px)活性随着日粮硒含量的提高而升高。当日粮硒含量在0.11~0.41 mg/kg范围内时,肝脏和肌肉组织中的硒含量以及GSH-Px活性均随日粮硒浓度的升高而显著升高(P<0.05);当日粮中硒含量在0.41~0.61 mg/kg范围内时,肝脏和肌肉组织中的硒含量以及GSH-Px活性不再随日粮硒水平的增大而继续显著增大(P>0.05);2种组织中的硒含量和GSH-Px活性之间存在高度正相关。肝脏和肌肉组织中的丙二醛(MDA)含量随着日粮硒含量的提高而降低。当日粮硒含量范围在0.41~0.61 mg/kg内时,肝脏和肌肉中MDA含量均保持在较稳定水平上。因此,4~6月龄绒山羊日粮中硒含量为0.41 mg/kg时,已经能够满足其维持较高水平生长性能和组织抗氧化能力对硒的需要。  相似文献   

6.
三种硒源对生长肥育猪组织硒沉积及抗氧化能力的影响   总被引:5,自引:0,他引:5  
将纳米硒、酵母硒和亚硒酸钠3种硒源分别以0.3、0.5、0.8mg/kg3个硒水平添加到基础日粮中,配制成试验日粮,基础日粮作对照,研究三种硒源对生长肥育猪组织硒沉积和抗氧化能力的影响。结果显示:①三种硒源添加浓度在0.3~0.8mg/kg水平范围内肥育猪的生长性能差异不显著(P>0.05),但酵母硒和纳米硒的添加能够较大幅度地提高日增重和降低料重比,有促进生长性能的趋势。②补加三种硒源的肥育猪,全血中GSH-Px的活性、SOD活性均极显著高于对照组;添加酵母硒和纳米硒组血清中MDA含量均显著或极显著低于对照组和亚硒酸钠组,但亚硒酸钠组和对照组差异不显著(P>0.05),纳米硒以0.5mg/kg添加量的效果较好。③3个补硒组的肝脏、肾脏中硒含量均显著或极显著高于对照组,其中纳米硒组肝脏中硒含量极显著高于亚硒酸钠组(P<0.01),与酵母硒组差异不显著(P>0.05)。  相似文献   

7.
本试验研究了利用富硒紫云英提高乳硒含量的效果及其对产奶量、乳脂、乳蛋白、乳中矿物质、全血GSH—Px活性的影响。试验表明:紫云英能促进奶牛对硒的吸收。以富硒紫云英的效果最好.可较大幅度增加乳中硒的含量;饲喂普通紫云英也可增加乳中硒的含量.添加无机硒也可增加乳中硒的含量.但利用率低。富硒紫云英、普通紫云英和无机硒对乳脂、乳糖和乳蛋白含量和乳中K^+、Na^+含量没有显著的影响。但对乳中Ca^2+、Mg^2+含量影响较大。全血GSH—Px活性受饲料中硒水平的影响显著。紫云英对奶牛血中GSH—Px活性比无机硒、对照组均明显提高.富硒紫云英、无机硒和普通紫云英处理组中GSH—Px活性比对照组分别提高了151.23%、87.15%和46.53%。富硒紫云英对产奶性能有较大的提高.生产周期相对延长。  相似文献   

8.
富硒麦芽硒在鸡蛋中的分布及蛋鸡对其相对生物利用率   总被引:11,自引:1,他引:10  
采用短期饲喂试验研究了富硒麦芽硒在鸡蛋中的沉积以及蛋鸡对其相对生物利用率。将30羽70周龄,产蛋率60%的伊莎蛋鸡随机均分为3组,A组为对照组,饲以基础日粮(含硒0.23mg/kg);B、C组为试验组,B组饲以基础日粮加亚硒酸钠,日粮含硒(0.70±0.03)mg/kg,C组饲以基础日粮加富硒麦芽,日粮含硒(0.72±0.02)mg/kg。试验过程中观察蛋鸡的生产性能,定期从各组鸡所产蛋中随机抽取5枚测定蛋清、蛋黄硒含量,计算总硒量。试验结束时,每组鸡全部扑杀,测定其全血、肝、肾硒含量和GSH-Px的活性。结果显示,日粮中加硒可提高鸡蛋、肝、肾硒含量和全血、肝、肾GSH-Px活性,但对蛋鸡生产性能无显著影响;与亚硒酸钠一样,饲喂富硒麦芽鸡所产蛋中的硒主要存在于蛋黄中;以亚硒酸钠的相对生物利用率为100%计,富硒麦芽硒提高肝、肾硒含量和GSH-Px活性的相对生物利用率分别为86.4%、98%、116%、111%。  相似文献   

9.
试验通过在公鸡日粮中添加不同水平亚硒酸钠,研究硒在公鸡组织中的沉积和对血液抗氧化能力的影响,为亚硒酸钠在鸡养殖业中的应用提供参考依据。选取80只体重接近、健康无疾病的海兰白成年公鸡,随机分成4组,每组20只,分别在日粮中添加0、0.5、1、2 mg/kg的亚硒酸钠。试验结束时,采集肝脏、肾脏、心、肺、脾、睾丸以及血液,测定硒含量,并分析血液中的谷胱甘肽过氧化物酶(GSH-Px)活性、超氧化物歧化酶(SOD)活性和总抗氧化能力(T-AOC)等。结果表明:组织和血液中硒含量随日粮硒含量的增加而升高,除心肌组织以外,各组之间差异显著(P<0.05);血液中的SOD、T-AOC活性随着日粮硒含量的增加而逐渐增加,且各组之间差异显著(P<0.05);适量的硒元素可以提高GSH-Px的活性,但过量的硒元素又会增加脂质过氧化反应,造成MDA含量升高,从而对组织细胞造成不良影响。结果提示:适量的硒可以提高鸡组织和血液中的硒含量,也可以提高血液的抗氧化能力,且提倡适宜的浓度为0.5 mg/kg。  相似文献   

10.
本研究以酵母硒为原料制备了3种工艺的硒产品(颗粒硒、粉体硒和水解硒),并对比研究亚硒酸钠与颗粒硒、粉体硒和水解硒对育肥猪生长性能、血清抗氧化指标及硒在组织中沉积的影响。结果表明:颗粒硒、粉体硒和水解硒组的粗蛋白质、总硒含量无明显差异,但水解硒组的酸溶蛋白、氨基酸态氮和溶解率明显提高;从生长性能指标来看,不同硒源对育肥猪的平均日增重(ADG)、平均日采食量(ADFI)和料重比(F/G)无显著影响(P> 0.05);从抗氧化指标来看,相比亚硒酸钠组,水解硒组和粉体硒组谷胱甘肽过氧化物酶(GSH-Px)的含量显著提高(P <0.05);从血清、肝脏、和肌肉中硒含量来看,相比亚硒酸钠组,颗粒硒组、粉体硒组和水解硒组血清中硒的含量显著提高(P<0.05),并且粉体硒组和水解硒组的肝脏和肌肉总硒含量显著高于亚硒酸钠组(P <0.05)。综上所述,水解酵母硒能提高硒酵母的酸溶蛋白含量,同时提高育肥猪的抗氧化性能及硒在组织中的快速沉积。  相似文献   

11.
A total of 64 weanling pigs was used in a randomized complete-block experiment to evaluate the efficacy of various inorganic Se levels on weekly Se balance measurements over a 5-wk post-weaning period. Four-week-old weaned pigs were fed a 20% protein, corn-soybean meal diet supplemented with 0, .3, .5 or 1.0 ppm Se from sodium selenite. Eight pigs were allotted by weight, litter and sex to each metabolism crate. A 2-d preliminary period followed by a 5-d collection period was conducted for five weekly periods. Feed intake was provided ad libitum but was similar between dietary Se levels. Fecal Se excretion increased each week and with increasing dietary Se level. Apparent digestibility of Se was relatively constant for each period when inorganic Se was fed, averaging approximately 70%, whereas it ranged between 30 to 40% for pigs fed the basal diet during wk 2 through 5. Urinary Se decreased during the postweaning periods for pigs fed the basal diet, but increased linearly as dietary Se increased during the initial 2-wk postweaning period and then quadratically during wk 3 through 5. There was a net loss of Se from the body when the Se-unsupplemented basal diet was fed during the initial 2 wk postweaning, whereupon, it became positive. Selenium retention in pigs supplemented with inorganic Se increased each week of the trial. When Se retention was expressed in relation to Se intake, the resulting regression was linear (R2 = .99), suggesting that Se retention in the postweaning pig increased in direct proportion to the amount consumed when diets contained up to 1.0 ppm Se.  相似文献   

12.
Monensin is an ionophoretic antibiotic, which selectively transports alkali metal cations across biological membranes. In growing swine, monensin toxicosis causes acute, degenerative cardiac and skeletal myopathy resembling vitamin E-selenium deficiency. Selenium is an essential trace element incorporated in glutathione peroxidase (GSH-Px), an antioxidant enzyme system that protects subcellular membranes. In our study, we examined the effects of monensin on body weight, Se balance, antioxidant status, and serum concentrations of selected minerals in growing pigs that were genetically hypo- or hyperselenemic (hypo-Se and hyper-Se, respectively). Three groups of eight 8-week-old pigs, each comprised of 4 hypo-Se and 4 hyper-Se pigs (76.4 +/- 3.0 and 106.3 +/- 10.3 ng of Se/ml of serum, respectively), were fed standard diets containing 0.1 mg of supplemental Se/kg of body weight, and either 0, 200, or 400 mg of monensin/kg for a 77-day period, followed by a 28-day monensin withdrawal period. On days 0, 7, 28, 56, 70, and 98, all pigs were weighed and blood was collected for determination of serum GSH-Px, creatine phosphokinase, and aspartate transaminase values, as well as serum concentrations of vitamin E, Se, Ca, Cu, Fe, K, Mg, Na, P, and Zn. Significance of main effects of monensin treatment, genetic Se status, and their interactions was tested by Fisher's variance ratio test, followed by conditional comparison of treatment means with a Bonferroni test. Signs of monensin toxicosis were not observed and monensin consumption had no effect on body weight, or serum creatine phosphokinase, aspartate transaminase, or Se values. However, pigs consuming monensin had consistently higher serum GSH-Px activities, possibly because of increased synthesis of this adaptive antioxidant enzyme. Interactions were not found between monensin and genetic Se status. Hyperselenemic pigs were heavier and had higher serum Se and GSH-Px values than hypo-Se pigs. Furthermore, hypo-Se and hyper-Se pigs were hypo- and hypercupremic, respectively, suggesting genetic regulation of copper status. It is likely that pigs with inadequate antioxidant status (hyposelenemia, hypocupremia) are more susceptible to diseases associated with cellular membrane damage, such as vitamin E-Se deficiency disease and monensin toxicosis.  相似文献   

13.
试验旨在研究氧化鱼油对育肥猪后期生产性能和冷藏生猪肉肉质的影响以及硒和维生素E的抗氧化作用。将40头DLY杂交猪(59.4kg)分为4个处理,对照组和3个添加剂组(0.3mg/kg硒,100mg/kg维生素E,0.3mg/kg硒+100mg/kg维生素E)。试猪平均体重为81.3kg时,将每个处理的10头猪各分为2组,分别在日粮中添加5%新鲜和氧化鱼油,试猪于平均体重109.8kg时屠宰取样。结果表明:①各处理组血清乳酸脱氢酶(LDH)和冷藏0~6d肉样的TVB-N、pH、L*无显著差异。②氧化鱼油显著提高肌肉丙二醛(MDA)含量,肉色b*值和血清尿素氮(BUN)、丙二醛(MDA)(P0.05);③油脂和添加剂在日增重(ADG)、滴水损失、肉色a*值、血清超氧化物歧化酶(SOD)和谷胱甘肽过氧化物酶(GPx)活性上表现显著的互作效应(P0.05)。本试验结果表明育肥后期添加5%氧化鱼油5周,对冷藏2d肉样b*值和2、4d肉样MDA含量有显著影响,硒和维生素E表现显著的抗氧化效应和与氧化鱼油的互作效应,硒+维生素E的添加在氧化鱼油组的作用效应大于新鲜鱼油组。  相似文献   

14.
不同硒水平对幼鲤生产性能和免疫功能的影响   总被引:1,自引:0,他引:1  
选择体重约10.4 g的健康幼鲤960尾,随机分为8组,每组3个重复,每个重复40尾,分别饲喂添加硒(亚硒酸钠,分析纯)0、0.1、0.2、0.3、0.4、0.5、0.6、0.7 mg/kg的8种不同饵料,试验期90 d。结果表明:随着饵料中硒添加水平的增加,幼鲤的增重和成活率提高,饵料系数降低,添加硒0.4mg/kg时,幼鲤生产性能最佳(P<0.05);添加0.3~0.5 mg/kg硒,可显著提高幼鲤头肾和脾脏重及其体指数,增加血液红细胞数量,降低白细胞数量,提高血清IgM水平和攻毒后成活率、血清溶菌酶活力及血清凝集抗体效价(P<0.05),从而增强幼鲤免疫功能和对疾病的抵抗力。幼鲤体增重、饵料系数、头肾重量、脾脏重量、血清溶菌酶活力和IgM抗体水平与饵料硒添加量呈显著的二次曲线相关。根据上述指标确定的最适硒水平为0.396~0.529 mg/kg。  相似文献   

15.
The effect of high dietary selenium (Se) on the reproductive performance, growth and health in pigs was examined. Addition of 0 to 16 mg Se per kg feed to sows and their piglets up to nine weeks of age did not cause any manifest toxic effect. None of the sows died due to the Se treatment. The piglets were all fullborn and showed no macroscopic abnormalities. The treatment did not influence neither the number of liveborn and stillborn piglets in the litter, nor the survival of the piglets until 9 weeks of age. The weight of the whole litter at birth was unaffected by the Se supplementation, while there was a significant difference in body weight of the piglets at 9 weeks of age. The weaned pigs receiving 8 or 16 mg Se per kg feed had a reduced feed intake. As the feed utilization was unaffected by treatment, these pigs had a significantly lower weight at 9 weeks of age.  相似文献   

16.
A randomized, blocked 23 factorial experiment was conducted with 48 young pigs. The treatment factors were: 2 levels of selenium (55 and 115 µg/kg), 2 levels of vitamin E (3 and 53 mg/kg) and 2 levels of the antioxidant feed additive Ethoxyquin (0 and 150 mg/kg). All pigs were kept in single pens and fed ad libitum throughout the experimental period of 9 weeks, i.e. from 3 to 12 weeks of age.Plasma, heart, liver and muscle Se levels as well as whole blood glutathione peroxidase activity (EC 1.11.1.9 GSH-Px) were significantly higher in pigs given a dietary supplement of Se than in pigs given no supplement of Se (P ≤ 0.001). The Se-supplemented pigs showed a tendency to lower mean serum transaminase activity (ASAT and ALAT) than unsupplemented pigs, but the influence was significant (P ≤ 0.05) only for the ALAT activity.Blood vit. E levels were higher for pigs receiving a supplement of vit. E than for unsupplemented pigs (P ≤ 0.001), and so was the resistance of red blood cells against lipid peroxidation (ELP), as expressed by lower ELP values.There were no effects of Ethoxyquin supplementation on the biochemical variables included in the study.The histological examination of heart muscle showed that the score for changes was negatively influenced by both Se and vit. E supplement (P ≤ 0.001) and to some extent also by Ethoxyquin supplement (P ≤ 0.05). The histological picture of m. long dorsi was influenced only by the vit. E supplement (P ≤ 0.01). No histological changes were found in the liver in this study. There were inverse relationships between whole blood GSH-Px defluorescence time and blood Se, and between ELP and whole blood vit. E (P ≤ 0.001).  相似文献   

17.
Effects of zeolite a or clinoptilolite in diets of growing swine   总被引:1,自引:0,他引:1  
Growth, nutrient balance, plasma ammonia levels and urinary p-cresol excretion were evaluated in growing pigs fed diets containing various levels of zeolite A or clinoptilolite. In one growth trial, crossbred pigs averaging 25 kg initial body weight were assigned to diets containing no zeolite, .3% zeolite A or .5% clinoptilolite for a 6-wk growing phase trial. Average daily gain (ADG), average daily feed intake (ADF) and feed/gain (F/G) were unaffected by supplementation of either zeolite in the diet, but metabolizable energy (ME) utilization was improved by feeding diets containing either zeolite. A second growth trial utilized the same crossbred pigs, which averaged 65 kg initial body weight, and were assigned to diets containing no zeolite, 1% zeolite A or 5% clinoptilolite for an 8-wk finishing phase trial. Average daily gain, ADF, and ME utilization were unaffected by feeding either zeolite diet, while F/G was increased in pigs fed the diet containing 5% clinoptilolite. In two nutrient balance trials, 16 crossbred pigs averaging 7.5 kg in initial body weight were fed diets containing 0, 1, 2 or 3% zeolite A in one trial and 16 crossbred pigs averaging 7.0 kg initial body weight were fed diets containing 0, 2.5, 5.0 or 7.5% clinoptilolite in a second trial. In both trials, digestible energy, ME, N-corrected ME and ME corrected for N balance and zeolite levels were linearly reduced as increasing amounts of either zeolite were fed. Daily fecal N increased and apparent digestibility of N was linearly reduced by feeding increasing amounts of zeolite A or clinoptilolite. Biological value of protein was improved linearly as higher levels of zeolite A were fed, indicating that there may be some ammonia binding to zeolite A in the gastrointestinal tract. Net protein utilization was reduced by feeding increasing levels of clinoptilolite in the diet. Calcium, P, Mg, Na, K and Fe retentions were linearly reduced by feeding increasing amounts of zeolite A in the diet, while increasing levels of clinoptilolite caused only P retention to be linearly reduced. Both free and conjugated forms of urinary p-cresol were linearly reduced by feeding increasing levels of clinoptilolite. Plasma ammonia levels were reduced at subsequent bleedings after a meal and by increasing levels of clinoptilolite.  相似文献   

18.
Selenium toxicosis was diagnosed in feeder pigs on a central Michigan farm. Use of a commercial supplement, found to contain approximately 20 times the intended Se concentration, resulted in a Se concentration of 8.1 mg/kg of the complete feed. This was fed for 34 days during which daily feed consumption decreased approximately 35%, several pigs developed weakness and forelimb paresis, and 1 pig died. The highest serum Se concentration measured was 1,550 ng/ml (normal range, 140 to 190 ng/ml). Normal feed consumption returned when an alternative feed was provided. Mean serum Se concentrations of representative pigs, monitored over the subsequent 26 days, decreased from 905 to 258 ng/ml. Histologic examination of a recovering pig revealed skeletal and cardiac myopathy and bilaterally symmetric malacia of the gray matter of the ventral horns of the spinal cord. During the developing toxicosis, the pigs consumed an estimated 11.4 mg of Se/pig/d.  相似文献   

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