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1.
为确定射干地龙颗粒防治鸡肾型传染性支气管炎的临床效果,将其用于鸡肾型传染性支气管炎病鸡群的防治。试验将27日龄的肾型传染性支气管炎病雏鸡1500只随机分成三组,每组500只。Ⅰ组用0.5%碳酸氢钠(Na HCO3)饮水,Ⅱ组为空白对照组,Ⅲ组以射干地龙颗粒0.5g/kg.体重饮水,连续治疗7 d。试验结果:Ⅰ组、Ⅱ组、Ⅲ组死亡率分别为5%(25/500)、23.8%(119/500)、3.4%(17/500)。试验证明,射干地龙颗粒治疗肾型传染性支气管炎具有较好疗效。  相似文献   

2.
鸡肾病变型传染性支气管炎的诊断与防治鸡肾病变型传染性支气管炎(简称肾型传炎)是一种急性,有高度接触性传染的呼吸道疾病,以气管罗音、咳嗽、打喷嚏、腹泻为特征。近年来,在专业户的规模饲养过程中,此病发生率逐渐增高,死亡率达20—40%,给养殖户造成较大的...  相似文献   

3.
近几年鸡肾型传染性支气管炎的发病率逐年增加,死亡率比较高。80%蛋鸡发病后会影响产蛋率,导致蛋鸡产蛋量达不到高峰。而且发病日龄越小,死亡率越高,对后期产蛋率影响越大,一般会导致产蛋率下降40%-60%不等,严重影响养禽业的生产。鸡肾型传染性支气管炎属传染性支气管炎的1种,是在特定的环境条件下,某些嗜肾性传染性支气管炎病毒在病鸡全身感染过程中对肾脏产生的损害作用。  相似文献   

4.
5组 12日龄雏鸡人工感染鸡肾型传染性支气管炎病毒 (IBV),攻毒后 36小时出现临床症状,此时分别按 3‰、 2‰、 1‰的浓度给鸡连续饮水投服肾复康治疗,连用 3天,同时选用“立服能” (Nephry1)作药物治疗对照,并测定了健康对照鸡、肾型 IB发病鸡、治愈鸡血清尿酸含量。从攻毒开始至 14天后试验结束,治疗组的死亡率分别为 3.3%、 6.6%、 13.3%,对照药物治疗组为 6.6%,人工发病未治疗组临床症状、病理变化都较典型,死亡率为 40%,健康对照组无死亡。由此可见,肾复康通过促进尿酸排泄,明显降低了鸡肾型传染性支气管炎的死亡率,且和“立服能”的疗效相近。  相似文献   

5.
中药治疗鸡肾型传染性支气管炎临床试验研究   总被引:5,自引:0,他引:5  
由两种兽用中药复方制剂禽族得乐和复方黄芪治疗鸡肾型传染性支气管炎,实验表明,禽族得乐治疗患肾型传染性支气管炎鸡群,其临床症状消失快于复方黄芪。  相似文献   

6.
本试验采取随机分组,病理模型复制的方法,试验中将14日龄AA肉雏鸡240只随机分为受试药物组(高、中、低3个剂量)、中药对照组、西药对照组、疫苗对照组、阴性对照组、健康对照组共8个组,每组30只,以验证中药荆芥组方对鸡肾型传染性支气管炎的效果。将试验鸡人工感染肾型传染性支气管炎病毒(IBV),观察中药组方对雏鸡保护作用。结果表明,本组方对肾型传染性支气管炎病毒感染雏鸡具有明显的保护作用,可以用于鸡肾型传染性支气管炎的预防和治疗。  相似文献   

7.
鸡肾型传染性支气管炎(以下简称肾传支)是由鸡传染性支气管炎致肾病变型毒株引起的一种鸡的急性、高度接触性传染病。通过对安宁渠及周围地区发生的肾传支的诊治,说明肾传支在本地区广泛存在且危害严重,送检病例中鸡肾型传染性支气管炎发病率20%,病死率30%~40%,主要因肾功能衰竭、自体中毒引起死亡。经诊治用以肾肿解毒药、抗病毒药物及中药为主的综合性防治措施治疗该病效果显著,用肾型传染性支气管炎弱毒苗配合油乳剂灭活苗防疫免疫保护有效。  相似文献   

8.
鸡肾型传染性支气管炎(肾型IB)是由肾型鸡传染性支气管炎病毒(肾型IBV)所引起的鸡的一种以肾脏病变为主的高度接触性病毒性传染病。它可引起雏鸡死亡,产蛋鸡产蛋量和蛋的质量下降,是目前发生较多,流行范围广,雏鸡死亡高的一种严重传染病之一。该病给养鸡业造成了巨大的损失,因此,正确诊断和防治该病已成为广大养鸡户十分关注的问题。为此,笔者对某肉鸡场发生鸡肾型传染性支气管炎的诊治经验介绍一下,以供养鸡户借鉴。  相似文献   

9.
肾型传支发病鸡群传支抗体变化规律的研究   总被引:1,自引:0,他引:1  
鸡肾型传染性支气管炎是由冠状病毒属的禽传染性支气管炎病毒(IBV)引起的一种以侵害鸡肾脏为主的急性、高度接触性传染病,对呼吸道和泌尿生殖道造成损伤。由于本病无特异治疗方法,给养鸡业造成极大损失。为了监测肾型传支发病鸡群的抗体消长情况,  相似文献   

10.
近几年来,在鸡病的诊治中,发现有肾肿病变的病冽日益增多。引起鸡肾肿病变的病因很多,其中以肾型传染性支气针灸、鸡甘保罗病、营养代谢病引起的肾肿、尿酸盐沉积最为常见,现将部分来稿摘登如下。一、肾型传染性支气管炎引起的肾昨河南省淇县禽病防治所曲‘k林,山西省农科院兽研所王红宝、郭雪丽,河南省滑县高手良西鸡场席视本,陕西榆林畜牧兽医中心站薛长春,浙江省杭州币近江种鸡场徐伟华等来稿,阐述了引起鸡肾肿、尿酸盐沉积的病因,临诊表现,病理剖检变化及实验室的诊断方法。着重介绍了肾型传染性支气管炎的防治:1.不论什么…  相似文献   

11.
试验选用96头平均体重14.82 kg左右的杜×长×大断奶仔猪,随机分成4组,每组3栏,每栏8头(公母各半)。对照组饲喂基础日粮,试验1、2、3组分别添加1%80目白术、0.2%白术多糖和1%微米白术。试验期30 d。结果表明:在生长性能方面,与对照组相比,1%微米白术添加组可显著提高日增重(P0.05)、降低饲料增重比和腹泻率,而且效果优于1%80目白术组和0.2%白术多糖组,在肠道形态和肠道微生态区系方面,与对照组相比,日粮添加1%80目白术、0.2%白术多糖、1%微米白术均可不同程度的提高十二指肠和空肠的绒毛高度,加深十二指肠和空肠的隐窝深度,并且增加肠道微生态区系的多样性,其中以1%微米白术添加组的效果最佳。  相似文献   

12.
Sissay, M.M., Uggla, A. and Waller, P.J., XXXX. Prevalence and seasonal incidence of nematode parasites and fluke infections of sheep and goats in eastern Ethiopia. Tropical Animal Health and Production, XXXX. A 2-year abattoir survey was carried out to determine the prevalence, abundance and seasonal incidence of gastro-intestinal (GI) nematodes and trematodes (flukes) of sheep and goats in the semi-arid zone of eastern Ethiopia. During May 2003 to April 2005, viscera including liver, lungs and GI tracts were collected from 655 sheep and 632 goats slaughtered at 4 abattoirs located in the towns of Haramaya, Harar, Dire Dawa and Jijiga in eastern Ethiopia. All animals were raised in the farming areas located within the community boundaries for each town. Collected materials were transported within 24 h to the parasitology laboratory of Haramaya University for immediate processing. Thirteen species belonging to 9 genera of GI nematodes (Haemonchus contortus, Trichostrongylus axei, T. colubriformis, T. vitrinus, Nematodirus filicollis, N. spathiger, Oesophagostomum columbianum, O. venulosum, Strongyloides papillosus, Bunostomum trigonocephalum, Trichuris ovis, Cooperia curticei and Chabertia ovina), and 4 species belonging to 3 genera of trematodes (Fasciola hepatica, F. gigantica, Paramphistomum {Calicohoron} microbothrium and Dicrocoelium dendriticum) were recorded in both sheep and goats. All animals in this investigation were infected with multiple species to varying degrees. The mean burdens of adult nematodes were generally moderate in both sheep and goats and showed patterns of seasonal abundance that corresponded with the bi-modal annual rainfall pattern, with highest burdens around the middle of the rainy season. In both sheep and goats there were significant differences in the mean worm burdens and abundance of the different nematode species between the four geographic locations, with worm burdens in the Haramaya and Harar areas greater than those observed in the Dire Dawa and Jijiga locations. Similar seasonal variations were also observed in the prevalence of flukes. But there were no significant differences in the prevalence of each fluke species between the four locations. Overall, the results showed that Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Fasciola and Paramphistomum species were the most abundant helminth parasites of sheep and goats in eastern Ethiopia.  相似文献   

13.
1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) is an alkylating agent in the nitrosourea subclass. A prospective evaluation of CCNU was done to determine the maximally tolerated dosage of CCNU in tumor-bearing cats. Response data were obtained when available. Twenty-five cats were treated with CCNU at a dosage of 50-60 mg/m3 body surface area. Complete hematologic data were available for 13 cats. Neutropenia was the acute dose-limiting toxicity. The median neutrophil count at the nadir was 1,000 cells/microL (mean, 2,433 cells/microL; range, 0-9,694 cells/microL). The time of neutrophil nadir was variable, occurring 7-28 days after treatment, and counts sometimes did not return to normal for up to 14 days after the nadir. Based on these findings, a 6-week dosing interval and weekly hematologic monitoring after the 1st treatment with CCNU are recommended. The nadir of the platelet count may occur 14-21 days after treatment. The median platelet count at the nadir was 43,500 cells/microL. No gastrointestinal, renal, or hepatic toxicities were observed after a single CCNU treatment, and additional studies to evaluate the potential for cumulative toxicity should be performed. Five cats with lymphoma and 1 cat with mast cell tumor had measurable responses to CCNU. Phase II studies to evaluate antitumor activity should be completed with a dosing regimen of 50-60 mg/m3 every 6 weeks.  相似文献   

14.
15.
Our particular attention in this article was given to natural mediators for macrophages isolated from the sites of tissue injury. A number of chemotactic factors, which may satisfy many criteria making them acceptable as inflammatory leucocyte chemotactic factors, has been separated. Among them, our laboratory has isolated three macrophage (monocyte) chemotactic factors (MCF-a, -b and -c). Their purification, characterization and functional specificity are discussed.  相似文献   

16.
Human and equine athletes are reported to have a high prevalence of gastric disease, and anecdotal evidence suggests a similar phenomenon applies to racing sled dogs. To investigate the prevalence of gastric disease in racing sled dogs, we conducted 2 gastroscopy studies on dogs competing in the annual Iditarod Sled Dog Race. A pilot study of dogs that were either dropped from the 2000 Iditarod Sled Dog Race because of illness or that finished the race indicated that, approximately 5 days after competing, 10 of 28 dogs (35%) had endoscopic evidence of gastric ulceration, erosion, or hemorrhage. The next year, an endoscopic study of 73 dogs participating in the 2001 Iditarod race was performed in order to evaluate a larger population of dogs. Data from 70 of these dogs could be used; 34 (48.5%) had ulceration, erosion, gastric hemorrhage, or some combination of these findings. When this group of 70 dogs was compared retrospectively to a control group of 87 dogs presented to the Texas A&M University (TAMU) Veterinary Medical Teaching Hospital, the Iditarod sled dogs had a significantly higher prevalence (P = .049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large.  相似文献   

17.
Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically significant difference in urine volume over 24 hours between methods; however, urine volume was significantly greater after CRI compared with IA during the first 8 hours ([median 25th percentile, 75th percentile]: 9.6 L [8.9, 14.4] for CRI versus 5.9 L [5.3, 6.0] for IA). CRI produced a more uniform urine flow, decreased fluctuations in plasma volume, and suppressed renal concentrating ability throughout the infusion period. Potassium, Ca, and Cl excretion was greater during CRI than IA (1,133 mmol [1.110, 1,229] versus 764 mmol [709, 904], 102.7 mmol [96.0, 117.2] versus 73.3 mmol [65.0, 73.5], and 1,776 mmol [1,657, 2.378] versus 1,596 mmol [1,457, 1,767], respectively). Elimination half-lives of furosemide were 1.35 and 0.47 hours for CRI and IA, respectively. The area under the excretion rate curve was 1,285.7 and 184.2 mL x mg/mL for CRI and IA, respectively. Furosemide CRI (0.12 mg/kg/h) for 8 hours, preceded by a loading dose (0.12 mg/kg), is recommended when profound diuresis is needed acutely in horses.  相似文献   

18.
Genetic variations in chromosome Y are enabling researchers to identify paternal lineages, which are informative for introgressions and migrations. In this study, the male‐specific region markers, sex‐determining region‐Y (SRY), amelogenin (AMELY) and zinc finger (ZFY) were analysed in seven Turkish native goat breeds, Angora, Kilis, Hair, Honaml?, Norduz, Gürcü and Abaza. A SNP in the ZFY gene defined a new haplotype Y2C. All domestic haplogroups originate from Capra aegagrus, while the finding of Y1A, Y1B, Y2A and Y2C in 32, 4, 126 and 2 Turkish domestic goats, respectively, appears to indicate a predomestic origin of the major haplotypes. The occurrence of four haplotypes in the Hair goat and, in contrast, a frequency of 96% of Y1A in the Kilis breed illustrate that Y‐chromosomal variants have a more breed‐dependent distribution than mitochondrial or autosomal DNA. This probably reflects male founder effects, but a role in adaptation cannot be excluded.  相似文献   

19.
The objective of this report was to characterize 20-year changes in proportion of calcium oxalate (CaOx) calculi and struvite calculi in dogs, and associations with breed, age, and sex. In this retrospective study, results of analysis of urinary calculi from dogs were reviewed for specimens received between July 1, 1981, and December 31, 2001. Breed, sex, age, year of submission of the specimen, and mineral type(s) were analyzed statistically. CaOx or Struvite or both were contained in 18,966 of 20,884 (91%) specimens. For both sexes, a 20-year statistically significant increase was observed in the proportion of calculus specimens that contained CaOx. The increase in this proportion was greater in females (1% to 31%) than in males (18% to 82%). From 1998 to 2001, when proportions may have plateaued, the odds of specimens containing CaOx were markedly higher in 18 breeds, markedly lower in 5 breeds, and not significantly different in 13 breeds compared with crossbreds. For both sexes, a 20-year statistically significant decrease was observed in the proportion of calculus specimens that contained struvite. This decrease in proportion was greater for males (79-16%) than for females (97-68%). From 1998 to 2001, when proportions plateaued, the odds of calculi containing struvite were markedly lower in 20 breeds, markedly higher in 1 breed, and not significantly different in 15 breeds when compared with crossbreds. Breed, age, and sex were associated statistically with CaOx or struvite urolithiasis. In conclusion, there appears to have been a long-term increase in the proportion of specimens of canine urinary calculi that contain CaOx as well as a long-term decrease in the proportion of specimens of calculi that contain struvite for both male and female dogs. The rate of change appeared to begin leveling off in the period 1998 to 2001. The recent proportion of dogs with either CaOx- or struvite-associated urolithiasis may depend on breed, age, and sex, and on interactions among these 3 factors.  相似文献   

20.
The epidemiology of H. placei and of other gastrointestinal nematodes in yearling dairy cattle was examined on two farms in Kiambu District, central Kenya during each of 13 one-month periods from April 1993 to April 1994. On each farm, 32 newly weaned dairy calves were given a single dose of albendazole and then placed on experimental pastures. Twelve of the animals were designated for bi-monthly slaughter (n = 2) and analysis of worm population characteristics and 20 were designated for blood and faecal collection and for weighing. Two parasite-free tracer calves were grazed alongside the weaner calves each month throughout the study period and were also slaughtered for analysis of worm populations. Faecal egg counts, haematological and serum pepsinogen determinations, herbage larval counts, and animal live weight changes were recorded monthly. The study revealed that Haemonchus placei, Trichostrongylus axei, Cooperia spp. and Oesophagostomum radiatum were responsible for parasitic gastroenteritis and that H. placei was the predominant nematode present in the young cattle on both farms. Faecal egg counts from resident cattle and necropsy worm counts revealed that pasture larval levels were directly related to the amount of rainfall. The total worm burdens in the animals were highest during the rainy season (March–June and October–December) and lowest during the dry seasons (July–September and January–February). The very low recovery of immature larvae of H. placei from the tracer calves indicated that arrested development is not a feature of the life cycle of this parasite in central Kenya. The maintenance of the parasite population depended on continuous cycling of infection between the host and the pasture. The agroclimatic conditions of the study area were such that, in general, favourable weather conditions for the development and survival of the free-living stages of gastrointestinal nematodes existed all year round.  相似文献   

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