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1.
周虚  董伟 《中国兽医学报》1994,14(4):350-353
本研究探讨了LRH-A3诱导初情期前北京黑猪发情排卵的效果及其内分泌机理。对6头150日龄母猪肌注LRH-A3,75μg/头。在注射后0,1,2,3和4h及注射后1,2,3和4d采血测定LH,FSH,E2和P4浓度。注射后10d取卵巢,根据卵巢上黄体数计算排卵率。结果表明:注射LRH-A3后,出现排卵和卵巢囊肿的母猪分别为4头(66.7%)和2头(33.7%)。4头排卵母猪中的3头和2头卵巢囊肿母  相似文献   

2.
五头断乳后非情期母猪分别在断乳后第2天(4头)和第36天(1头)肌注1,000IUhCG)H头猪都有单个或多个囊肿卵泡发生。4头母猪血浆E2在小范围内波动,表现安静发情.注射hCG后既不发情也不排卵的母猪没有出现排卵前LH峰,血浆孕酮水平很低(<1ng/ml)。结果表明用hCG治疗母猪卵巢功能低下,将诱导异常的卵泡生长和LH释放,导致排卵障碍和卵巢囊肿。  相似文献   

3.
五头断乳后非情期母猪分别在断乳后第2天(4头)和第36天(1头)肌注,1,000IUhUG)五头猪者有单个或多个囊肿卵泡发生,4头母猪血浆E2在小范围内波动,表现安静发情,注射hCG后既不发情也不排卵的母猪没有出现排卵前LH峰,血浆孕酮水平银低(<1ng/ml)。结果表明用hCG治疗母猪卵巢功能低下,将诱导异常的卵泡生长和LH释放,导致排卵障碍和卵巢囊肿。  相似文献   

4.
肌注PMSG+CHG、LRH-A或FSH+LH,能促使母果子狸发情、交配和产仔。PMSG500IU+HCG250IU,LRH-A50-100μgFSH160IU+LH100IU时催情效果较佳。使用上述药物,在每年1月30日在若进行第1次催情,果子狸可比自然状态提早约1个月于4月5日前后产下第1胎仔狸。仔狸20日龄断奶成活率较高。断奶后第15d对母猪第2次催情,7月中旬前后可产下第2胎仔狸,做到在较  相似文献   

5.
对45头供体母牛随机用FSH+LRH-A3和FSH进行超然处理。其中FSH+LRH-A3处理供体52头次,FSH处理供体22头次;FSH十LRH-A3处理组平均获得如数、可用胚胎数分别是10.1±8.0枚,7.4±6.9枚,与FSH处理组(二指标分别是9.3±6.2枚,3.6±2.7枚)相比,分别高8.6%、105.6%,且二组超排获得可用胚胎数差异显著(P<0.05)。  相似文献   

6.
肌注维生素促进停乳母猪同期发情试验   总被引:1,自引:0,他引:1  
试验选用长宁F1泌乳母猪72头,随机分为4组(VAD2,VE,VAD2+VE和对照组),每组18头,维生素处理的3组母猪,在停乳前1周,停乳当天分两次肌注VAD2,VE及VAD2+VE。经3个月的试验结果表明,VAS3组母猪停乳1周内的发情率,配种率为94.3%,停乳至发情的平均时间间隔为110h±8h ,配种后21d内的返情率为5.7%;VE组依次为87.7%,112h±14h,4.9%;VAD  相似文献   

7.
LRH—A3提高母猪繁殖力效应   总被引:1,自引:0,他引:1  
50头二产母猪(约×长)被随机均分为5组,Ⅰ组为空白对照组,Ⅱ,Ⅲ,Ⅳ,Ⅴ4个试验组分别于配种当天(0d)及配种后5,10和0+10d每头每次肌注LRH-A3(促黄体激素释放激素,促排3号)150μg,并在注药后当天及5,10,20,30和40d耳静脉采血,分离血浆;各组取2头分别于注药前及注药后0.5,1,2和4h采血,分离血清,测定其内分泌变化。结果,各试验组LH峰均在注药后2h,Ⅱ组峰值显著高于其他各组(P<0.05);配后10~30d,各试验组P4含量显著高于对照组;配后30d妊娠猪E1S含量达峰值,且与产仔数呈正相关(r=0.4032,n=46,P<0.01);产仔数及受胎率以Ⅴ组为最佳。  相似文献   

8.
GnRH类似物LRH—A3配合FSH对超排母牛胚胎质量的影响   总被引:5,自引:0,他引:5  
对45头供体母牛随机用FSH+LRH-A3和FSH进行超排处理。其中FSH+LRH-A3处理供体52头次,FSH处理供体22头次;FSH+LRH-A3头处理组平均获得卵数,可用胚胎数分别是10.1±8.0枚,7.4±6.9枚,与FSH处理组(二指标分别是9.3±6.2枚,3.6±2.7)相比,分别高8.6%,105.6%,且二组超排获得可用胚胎数差异显著(P<0.05)。  相似文献   

9.
促卵泡素3号(LRH-A3)、人绒毛膜促性腺激素(hCG)和孕马血清促性腺激素(PMSG)等3种外源性激素均可增加体外培养条件下牦牛垂体组织分泌LH和FSH的能力。培养液中LH和FSH含量与加入的LRH-A3量呈正相关,与加入的PMSG和hCG的量无显著关系  相似文献   

10.
促卵泡素3号(LRH-A3)、人绒毛膜促性腺激素(hCG)和孕马血清促性腺激素(PMSG)等3种外源性激素均可增加体外培养条件下牦牛垂体组织分泌LH和FSH的能力。培养液中LH和FSH含量与加入的LRH-A3量呈正相关,与加入的PMSG和hC的量无显著关系。  相似文献   

11.
试验选用96头平均体重14.82 kg左右的杜×长×大断奶仔猪,随机分成4组,每组3栏,每栏8头(公母各半)。对照组饲喂基础日粮,试验1、2、3组分别添加1%80目白术、0.2%白术多糖和1%微米白术。试验期30 d。结果表明:在生长性能方面,与对照组相比,1%微米白术添加组可显著提高日增重(P0.05)、降低饲料增重比和腹泻率,而且效果优于1%80目白术组和0.2%白术多糖组,在肠道形态和肠道微生态区系方面,与对照组相比,日粮添加1%80目白术、0.2%白术多糖、1%微米白术均可不同程度的提高十二指肠和空肠的绒毛高度,加深十二指肠和空肠的隐窝深度,并且增加肠道微生态区系的多样性,其中以1%微米白术添加组的效果最佳。  相似文献   

12.
Sissay, M.M., Uggla, A. and Waller, P.J., XXXX. Prevalence and seasonal incidence of nematode parasites and fluke infections of sheep and goats in eastern Ethiopia. Tropical Animal Health and Production, XXXX. A 2-year abattoir survey was carried out to determine the prevalence, abundance and seasonal incidence of gastro-intestinal (GI) nematodes and trematodes (flukes) of sheep and goats in the semi-arid zone of eastern Ethiopia. During May 2003 to April 2005, viscera including liver, lungs and GI tracts were collected from 655 sheep and 632 goats slaughtered at 4 abattoirs located in the towns of Haramaya, Harar, Dire Dawa and Jijiga in eastern Ethiopia. All animals were raised in the farming areas located within the community boundaries for each town. Collected materials were transported within 24 h to the parasitology laboratory of Haramaya University for immediate processing. Thirteen species belonging to 9 genera of GI nematodes (Haemonchus contortus, Trichostrongylus axei, T. colubriformis, T. vitrinus, Nematodirus filicollis, N. spathiger, Oesophagostomum columbianum, O. venulosum, Strongyloides papillosus, Bunostomum trigonocephalum, Trichuris ovis, Cooperia curticei and Chabertia ovina), and 4 species belonging to 3 genera of trematodes (Fasciola hepatica, F. gigantica, Paramphistomum {Calicohoron} microbothrium and Dicrocoelium dendriticum) were recorded in both sheep and goats. All animals in this investigation were infected with multiple species to varying degrees. The mean burdens of adult nematodes were generally moderate in both sheep and goats and showed patterns of seasonal abundance that corresponded with the bi-modal annual rainfall pattern, with highest burdens around the middle of the rainy season. In both sheep and goats there were significant differences in the mean worm burdens and abundance of the different nematode species between the four geographic locations, with worm burdens in the Haramaya and Harar areas greater than those observed in the Dire Dawa and Jijiga locations. Similar seasonal variations were also observed in the prevalence of flukes. But there were no significant differences in the prevalence of each fluke species between the four locations. Overall, the results showed that Haemonchus, Trichostrongylus, Nematodirus, Oesophagostomum, Fasciola and Paramphistomum species were the most abundant helminth parasites of sheep and goats in eastern Ethiopia.  相似文献   

13.
14.
1-(2-Chloroethyl)3-cyclohexyl-1-nitrosourea (CCNU) is an alkylating agent in the nitrosourea subclass. A prospective evaluation of CCNU was done to determine the maximally tolerated dosage of CCNU in tumor-bearing cats. Response data were obtained when available. Twenty-five cats were treated with CCNU at a dosage of 50-60 mg/m3 body surface area. Complete hematologic data were available for 13 cats. Neutropenia was the acute dose-limiting toxicity. The median neutrophil count at the nadir was 1,000 cells/microL (mean, 2,433 cells/microL; range, 0-9,694 cells/microL). The time of neutrophil nadir was variable, occurring 7-28 days after treatment, and counts sometimes did not return to normal for up to 14 days after the nadir. Based on these findings, a 6-week dosing interval and weekly hematologic monitoring after the 1st treatment with CCNU are recommended. The nadir of the platelet count may occur 14-21 days after treatment. The median platelet count at the nadir was 43,500 cells/microL. No gastrointestinal, renal, or hepatic toxicities were observed after a single CCNU treatment, and additional studies to evaluate the potential for cumulative toxicity should be performed. Five cats with lymphoma and 1 cat with mast cell tumor had measurable responses to CCNU. Phase II studies to evaluate antitumor activity should be completed with a dosing regimen of 50-60 mg/m3 every 6 weeks.  相似文献   

15.
Our particular attention in this article was given to natural mediators for macrophages isolated from the sites of tissue injury. A number of chemotactic factors, which may satisfy many criteria making them acceptable as inflammatory leucocyte chemotactic factors, has been separated. Among them, our laboratory has isolated three macrophage (monocyte) chemotactic factors (MCF-a, -b and -c). Their purification, characterization and functional specificity are discussed.  相似文献   

16.
Human and equine athletes are reported to have a high prevalence of gastric disease, and anecdotal evidence suggests a similar phenomenon applies to racing sled dogs. To investigate the prevalence of gastric disease in racing sled dogs, we conducted 2 gastroscopy studies on dogs competing in the annual Iditarod Sled Dog Race. A pilot study of dogs that were either dropped from the 2000 Iditarod Sled Dog Race because of illness or that finished the race indicated that, approximately 5 days after competing, 10 of 28 dogs (35%) had endoscopic evidence of gastric ulceration, erosion, or hemorrhage. The next year, an endoscopic study of 73 dogs participating in the 2001 Iditarod race was performed in order to evaluate a larger population of dogs. Data from 70 of these dogs could be used; 34 (48.5%) had ulceration, erosion, gastric hemorrhage, or some combination of these findings. When this group of 70 dogs was compared retrospectively to a control group of 87 dogs presented to the Texas A&M University (TAMU) Veterinary Medical Teaching Hospital, the Iditarod sled dogs had a significantly higher prevalence (P = .049) of gastric lesions. These findings suggest that, similar to athletes of other species, elite canine athletes have an increased prevalence of gastric disease compared to the canine population at large.  相似文献   

17.
Continuous rate infusion (CRI) of furosemide in humans is considered superior to intermittent administration (IA). This study examined whether furosemide CRI, compared with IA, would increase diuretic efficacy with decreased fluid and electrolyte fluctuations and activation of the renin-angiotensin-aldosterone system (RAAS) in the horse. Five mares were used in a crossover-design study. During a 24-hour period, each horse received a total of 3 mg/kg furosemide by either CRI (0.12 mg/kg/h preceded by a loading dose of 0.12 mg/kg IV) or IA (1 mg/kg IV q8h). There was not a statistically significant difference in urine volume over 24 hours between methods; however, urine volume was significantly greater after CRI compared with IA during the first 8 hours ([median 25th percentile, 75th percentile]: 9.6 L [8.9, 14.4] for CRI versus 5.9 L [5.3, 6.0] for IA). CRI produced a more uniform urine flow, decreased fluctuations in plasma volume, and suppressed renal concentrating ability throughout the infusion period. Potassium, Ca, and Cl excretion was greater during CRI than IA (1,133 mmol [1.110, 1,229] versus 764 mmol [709, 904], 102.7 mmol [96.0, 117.2] versus 73.3 mmol [65.0, 73.5], and 1,776 mmol [1,657, 2.378] versus 1,596 mmol [1,457, 1,767], respectively). Elimination half-lives of furosemide were 1.35 and 0.47 hours for CRI and IA, respectively. The area under the excretion rate curve was 1,285.7 and 184.2 mL x mg/mL for CRI and IA, respectively. Furosemide CRI (0.12 mg/kg/h) for 8 hours, preceded by a loading dose (0.12 mg/kg), is recommended when profound diuresis is needed acutely in horses.  相似文献   

18.
Genetic variations in chromosome Y are enabling researchers to identify paternal lineages, which are informative for introgressions and migrations. In this study, the male‐specific region markers, sex‐determining region‐Y (SRY), amelogenin (AMELY) and zinc finger (ZFY) were analysed in seven Turkish native goat breeds, Angora, Kilis, Hair, Honaml?, Norduz, Gürcü and Abaza. A SNP in the ZFY gene defined a new haplotype Y2C. All domestic haplogroups originate from Capra aegagrus, while the finding of Y1A, Y1B, Y2A and Y2C in 32, 4, 126 and 2 Turkish domestic goats, respectively, appears to indicate a predomestic origin of the major haplotypes. The occurrence of four haplotypes in the Hair goat and, in contrast, a frequency of 96% of Y1A in the Kilis breed illustrate that Y‐chromosomal variants have a more breed‐dependent distribution than mitochondrial or autosomal DNA. This probably reflects male founder effects, but a role in adaptation cannot be excluded.  相似文献   

19.
The objective of this report was to characterize 20-year changes in proportion of calcium oxalate (CaOx) calculi and struvite calculi in dogs, and associations with breed, age, and sex. In this retrospective study, results of analysis of urinary calculi from dogs were reviewed for specimens received between July 1, 1981, and December 31, 2001. Breed, sex, age, year of submission of the specimen, and mineral type(s) were analyzed statistically. CaOx or Struvite or both were contained in 18,966 of 20,884 (91%) specimens. For both sexes, a 20-year statistically significant increase was observed in the proportion of calculus specimens that contained CaOx. The increase in this proportion was greater in females (1% to 31%) than in males (18% to 82%). From 1998 to 2001, when proportions may have plateaued, the odds of specimens containing CaOx were markedly higher in 18 breeds, markedly lower in 5 breeds, and not significantly different in 13 breeds compared with crossbreds. For both sexes, a 20-year statistically significant decrease was observed in the proportion of calculus specimens that contained struvite. This decrease in proportion was greater for males (79-16%) than for females (97-68%). From 1998 to 2001, when proportions plateaued, the odds of calculi containing struvite were markedly lower in 20 breeds, markedly higher in 1 breed, and not significantly different in 15 breeds when compared with crossbreds. Breed, age, and sex were associated statistically with CaOx or struvite urolithiasis. In conclusion, there appears to have been a long-term increase in the proportion of specimens of canine urinary calculi that contain CaOx as well as a long-term decrease in the proportion of specimens of calculi that contain struvite for both male and female dogs. The rate of change appeared to begin leveling off in the period 1998 to 2001. The recent proportion of dogs with either CaOx- or struvite-associated urolithiasis may depend on breed, age, and sex, and on interactions among these 3 factors.  相似文献   

20.
<正>1.INTRODUCTION Ensuring transportation network security is one Of the most daunting challenges confronting homeland security agencies today.Significant research has been dedicated.To model and analyze the vulnerability of transportation systems,while notably fewer studies propose specific strategies for deploying defensive technologies to safeguard these systems.  相似文献   

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