Exploitation of early rains by a traditional cultivation technique in the West African Savanna     

R.J. Dunham 《Soil & Tillage Research》1983,3(2):123-133

A traditional cultivation technique for cereals in the West African Savanna is described. Measurements of soil moisture showed that at the start of the rainy season when rainfall is erratic, the technique assists an early-planted crop to survive dry spells by providing the maximum amount of available water close to the planting position. This is achieved by the ingenious device of making planting hills in the furrows between existing ridges. The essential features of this hill-in-furrow technique could be retained advantageously in mechanised cultivation systems.  相似文献   

Characterization of porcine xenoreactive cytotoxic T lymphocytes.     

D M Dunham  E C Hahn 《Veterinary immunology and immunopathology》1992,34(3-4):209-220

Cytotoxic T lymphocytes (CTL) against mouse P815 cells were detected after stimulation of porcine peripheral blood mononuclear cells (PBMC) with irradiated Balb/c splenocytes. In vivo priming prior to in vitro stimulation slightly enhanced CTL activity, but lysis of targets was undetectable from lymphocytes from non-immune or immune animals that were not cultured with mouse splenocytes. After primary culture with Balb/c (H-2d) splenocytes, specific killing of P815 (H-2d) targets and not L929 (H-2k) targets indicated that recognition was specific for the H-2 locus. Similarly, CTL primed by mouse cells from either of two congenic strains recognized targets with alleles homologous to the stimulating cells. The anti-murine CTL was confirmed to be a CD8+ T cell based on studies using specific monoclonal antibodies to the porcine CD4 or CD8 cells. The cells responsible for the cytotoxicity of P815 targets lacked the characteristics of non-specific NK cells because (1) naive PBMC were unable to lyse NK targets (K562 cells) during the 4 h cytotoxic assay and (2) CTL killing of P815 targets increased with time after primary stimulation, whereas killing of K562 cells remained low at all times. These results suggest that porcine CTL can be readily generated against the xenogeneic mouse major histocompatibility complex.  相似文献   

Dog and cat keeping in the Australian Capital Territory, 1993     

DW PAXTON 《Australian veterinary journal》1994,71(1):27-28

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An attempt to prevent acute toxoplasmosis in macropods by vaccination with Hammondia hammondi     

GL REDDACLIFF  SJ PARKER  JP DUBEY  PJ NICHOLLS  AM JOHNSON  DW COOPER 《Australian veterinary journal》1993,70(1):33-35

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American academy of veterinary pharmacology and therapeutics 14th biennial symposium     

Martinez M  Clark J  Dunham B  Hunter RP  Langston C  Lucas A  Jordan D 《Journal of veterinary pharmacology and therapeutics》2005,28(5):495-498

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Limited efficacy of an inactivated feline immunodeficiency virus vaccine     

Dunham SP  Bruce J  MacKay S  Golder M  Jarrett O  Neil JC 《The Veterinary record》2006,158(16):561-562

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Interleukin‐31: its role in canine pruritus and naturally occurring canine atopic dermatitis     

Andrea J. Gonzales  William R. Humphrey  James E. Messamore  Timothy J. Fleck  Gregory J. Fici  John A. Shelly  Janet F. Teel  Gary F. Bammert  Steven A. Dunham  Troy E. Fuller  Robert B. McCall 《Veterinary dermatology》2013,24(1):48-e12

Background – Interleukin‐31 (IL‐31) is a member of the gp130/interleukin‐6 cytokine family that is produced by cell types such as T helper 2 lymphocytes and cutaneous lymphocyte antigen positive skin homing T cells. When overexpressed in transgenic mice, IL‐31 induces severe pruritus, alopecia and skin lesions. In humans, IL‐31 serum levels correlate with the severity of atopic dermatitis in adults and children. Hypothesis/Objective – To determine the role of IL‐31 in canine pruritus and naturally occurring canine atopic dermatitis (AD). Animals – Purpose‐bred beagle dogs were used for laboratory studies. Serum samples were obtained from laboratory animals, nondiseased client‐owned dogs and client‐owned dogs diagnosed with naturally occurring AD. Methods – Purpose‐bred beagle dogs were administered canine interleukin‐31 (cIL‐31) via several routes (intravenous, subcutaneous or intradermal), and pruritic behaviour was observed/quantified via video monitoring. Quantitative immunoassay techniques were employed to measure serum levels of cIL‐31 in dogs. Results – Injection of cIL‐31 into laboratory beagle dogs caused transient episodes of pruritic behaviour regardless of the route of administration. When evaluated over a 2 h period, dogs receiving cIL‐31 exhibited a significant increase in pruritic behaviour compared with dogs that received placebo. In addition, cIL‐31 levels were detectable in 57% of dogs with naturally occurring AD (≥13 pg/mL) but were below limits of quantification (<13 pg/mL) in normal, nondiseased laboratory or client‐owned animals. Conclusions – Canine IL‐31 induced pruritic behaviours in dogs. Canine IL‐31 was detected in the majority of dogs with naturally occurring AD, suggesting that this cytokine may play an important role in pruritic allergic skin conditions, such as atopic dermatitis, in this species.  相似文献   

Correction to: Individual based modelling of fish migration in a 2-D river system: model description and case study     

Snyder  Marcía N.  Schumaker  Nathan H.  Ebersole  Joseph L.  Dunham  Jason B.  Comeleo  Randy L.  Keefer  Matthew L.  Leinenbach  Peter  Brookes  Allen  Cope  Ben  Wu  Jennifer  Palmer  John  Keenan  Druscilla 《Landscape Ecology》2019,34(5):1197-1197

Landscape Ecology - In the original publication of the article, the third author name has been misspelt. The correct name is given in this Correction. The original version of this article was revised.  相似文献   

The theropod ancestry of birds: new evidence from the late cretaceous of madagascar     

CA Forster  SD Sampson  LM Chiappe  DW Krause 《Science (New York, N.Y.)》1998,279(5358):1915-1919

A partial skeleton of a primitive bird, Rahona ostromi, gen. et sp. nov., has been discovered from the Late Cretaceous of Madagascar. This specimen, although exhibiting avian features such as a reversed hallux and ulnar papillae, retains characteristics that indicate a theropod ancestry, including a pubic foot and hyposphene-hypantra vertebral articulations. Rahona has a robust, hyperextendible second digit on the hind foot that terminates in a sicklelike claw, a unique characteristic of the theropod groups Troodontidae and Dromaeosauridae. A phylogenetic analysis places Rahona with Archaeopteryx, making Rahona one of the most primitive birds yet discovered.  相似文献   

Effects of cecropin peptides on bacteria pathogenic to fish   总被引：1，自引：0，他引：1  

A. K. Kjuul  E. E. Büllesbach  S. Espelid  R. Dunham  T. Ò. Jørgensen  G. W. Warr  . and  O. B. Styrvold 《Journal of fish diseases》1999,22(5):387-394

The antibacterial effects of synthetic cecropin B and cecropin P1 were tested against the fish-pathogenic bacteria Vibrio anguillarum, Vibrio salmonicida, Aeromonas salmonicida , Edwardsiella ictaluri and Yersinia ruckeri. Both cecropins were active against all bacteria tested, but the effect was strongly influenced by the growth media used. In brain heart infusion medium, the minimum inhibitory concentrations of cecropin B ranged from 0.3 to 1.3 μ m and from 0.3 to 1.0 μ m for cecropin P1, except for E. ictaluri , which was noticeably less sensitive to cecropin P1 (61 μ m ). The present authors have compared the bactericidal activity of these two peptides, showing that the killing rate for the selected bacteria was higher for cecropin B than for cecropin P1 . V. anguillarum was the most sensitive to the cecropins, and in the present study, no colony forming units were detected after 4 and 8 min of treatment with cecropin B and P1, respectively. Electron microscopy was performed to document the effect of cecropin on the bacterial surface.  相似文献