Hyperlipemia and Ketonuria in an Alpaca and a Llama     

David E. Anderson  Peter D. Constable  Kathleen E. Yvorchuk  Neil V. Anderson  Guy St-Jean  Linda Rock 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》1994,8(3):207-211

An alpaca and a llama in late stages of gestation were evaluated for lethargy, anorexia, and recumbency. Both camelids had cloudy, white, turbid serum, elevated serum triglyceride (1564, 5658 mg/dL, respectively) and cholesterol (158, 297 mg/dL, respectively) concentrations, and ketonuria. Signs of fetal stress were evident ultrasonographically in the alpaca, and a live cria was delivered by Cesarean section performed under general anesthesia. The alpaca developed severe metabolic acidosis, hepatic lipidosis, and acute renal failure secondary to renal lipidosis and died 36 hours after admission despite medical therapy. Histopathology revealed renal and hepatic lipidosis and neutrophilic pancreatitis. The cria died 72 hours after birth. The llama responded to IV electrolyte, dextrose, and regular crystalline insulin therapy. The pregnancy was maintained, and the llama was discharged from the hospital 20 days after admission. Two months after discharge, the llama gave birth to a live, 5 kg cria. Findings of hypertriglyceridemia, hypercholesterolemia, elevated sorbitol dehydrogenase activity, metabolic acidosis, azotemia, and ketonuria occurred in these two camelids. Based on this report, camelids appear to be similar to both horses and cattle in their response to severe energy imbalances in late gestation.  相似文献   

Ollulanus tricuspis in domestic cats - prevalence and methods of post-mortem diagnosis     

Guy PA 《New Zealand veterinary journal》1984,32(6):81-84

Ollulanus tricuspus is a parasite of the stomach of domestic cats and other animals, with a worldwide distribution. It can sometimes cause severe gastritis. Fifty-five cat stomachs were examined for O.tricuspis using three techniques. O.tricuspis was found in seven stomachs (13%) from adult cats; the number of parasites recovered from individual cats ranged from 9 to 119 (mean 54). The prevalence was higher than that previously recorded in New Zealand. Repeated dilution and sedimentation of the stomach contents and mucosal washings was found to be the most reliable detection method, being positive in all of the detected infections. Pepsin/HCI digestion of the stomach mucosa detected only 71% and punch sampling of the mucosa only 29% of these infections. This contrasts with an overseas study indicating that, in heavily infected cats, these techniques are similar in sensitivity. No macroscopic lesions were seen in the stomachs of infected cats.  相似文献   

Blood coagulation parameters in clinically normal intensively farmed red deer (Cervus elaphus) and fallow deer (Dama dama)     

Sutherland RJ  Saunders BW  Guy LA 《New Zealand veterinary journal》1985,33(1-2):14-16

Reference ranges for five parameters of blood coagulation were established in clinically normal farmed fallow deer (Dama dama) and red deer (Cervus elaphus). Storage of plasma at -15 degrees C resulted in small increases in activated partial thromboplastin time (APTT) for both species, and in the one stage prothrombin time (OSPT) of fallow deer, between days 1 and 30. These times were then stable between days 30 and 60. The fibrinogen levels of fallow deer plasma showed a small apparent increase over 60 days. These storage artefacts were not of sufficient magnitude to preclude the use of such plasma for diagnostic purposes although they could limit its use in research. Levels of fibrin/fibrinogen degradation products (FDP) were not affected by storage at -15 degrees C. Rabbit brain thromboplastin appeared adequate for OSPT determination in both species. The activated clotting time (ACT) is recommended as a field test for screening the intrinsic and common pathways of blood coagulation in deer.  相似文献   

Perceptions and opinions of pet owners in the United Sates about surgery,pain management,and anesthesia in dogs and cats          下载免费PDF全文

Bradley T. Simon DVM  MSc  DACVAA  Elizabeth M. Scallan DVM  MBA  MS  CVA  CCRP  Dirsko J. F. Von Pfeil DVM  DACVS  DECVS  DACVSMR  Daniel T. Boruta DVM  DACVAA  Rick Wall DVM  DACVSMR  CCRP  Belle M. Nibblett DVM  MVSc  DACVIM  O Odette DVM  DACVAA  Guy Beauchamp PhD  Paulo V. Steagall DVM  MSc  PhD  DACVAA 《Veterinary surgery : VS》2018,47(2):277-284

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Treatment of contaminated radial fracture in Sprague-Dawley rats by application of a degradable polymer releasing gentamicin     

Yuval Ramot  Michal Steiner  Netanel Amouyal  Yossi Lavie  Guy Klaiman  Abraham J. Domb  Abraham Nyska  Tal Hagigit 《Journal of toxicologic pathology》2021,34(1):11

Fracture-related infections remain a leading cause of morbidity and mortality. We aimed to establish a simple contaminated radial osteotomy model to assess the efficacy of a biodegradable polymer poly(sebacic-co-ricinoleic acid) [p(SA-RA)] containing 20% w/w gentamicin. A unilateral transverse osteotomy was induced in Sprague-Dawley (SD) rats, followed by application of Staphylococcus aureus suspension over the fracture. After successfully establishing the contaminated open fracture model, we treated the rats either systemically (intraperitoneal cefuroxime), locally with p(SA-RA) containing gentamicin, or both. Control groups included non-contaminated group and contaminated groups that were either untreated or treated with the polymer alone. After 4 weeks, the bones were subjected to micro-CT scanning and microbiological and histopathology evaluations. Micro-CT analysis revealed similar changes in the group subjected to both local and systemic treatment as in the non-contaminated control group. Lack of detectable bacterial growth was noted in most animals of the group subjected to both local and systemic treatment, and all samples were negative for S. aureus. Histopathological evaluation revealed that all treatment modalities containing antibiotics were highly effective in reducing infection and promoting callus repair, resulting in early bone healing. While p(SA-RA) containing gentamicin treatment showed better results than cefuroxime, the combination of local and systemic treatment displayed the highest therapeutic potential in this model.  相似文献   

Reference intervals for plasma,urinary, and salivary concentrations of free metanephrines in dogs: Relevance to the diagnosis of pheochromocytoma     

Marit F. van den Berg  Hans S. Kooistra  Guy C. M. Grinwis  Sebastiaan A. van Nimwegen  Martijn van Faassen  Ido P. Kema  Erik Teske  Sara Galac 《Journal of veterinary internal medicine / American College of Veterinary Internal Medicine》2023,37(1):173-183

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Assessment of insecticidal effects and selectivity of CAPA‐PK peptide analogues against the peach‐potato aphid and four beneficial insects following topical exposure     

Shun‐Hua Gui  Clauvis NT Taning  Kristof De Schutter  Qun Yang  Pengyu Chen  Mohamad Hamshou  Ronald J Nachman  Aniruddha A Pandit  Julian AT Dow  Shireen Davies  Guy Smagghe 《Pest management science》2020,76(10):3451-3458

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Response of snails and slugs to fragmentation of lowland forests in NW Germany     

Heike Kappes  Kurt Jordaens  Frederik Hendrickx  Jean-Pierre Maelfait  Luc Lens  Thierry Backeljau 《Landscape Ecology》2009,24(5):685-697

Habitat fragmentation is a major cause for species loss, but its effect on invertebrates with low active dispersal power, like terrestrial gastropods, has rarely been studied. Such species can not cross a hostile habitat matrix, for which the predictions of island theory, such as positive relations between species richness and patch size, should apply. In order to test this prediction, we studied gastropod species diversity by assessing gastropod assemblage characteristics from 35 sites in 19 fragments of deciduous old-growth forests in the Lower Rhine Embayment, Germany. Assemblages differed between larger (≥700 ha) and smaller forests (<400 ha), those of large forests held a higher percentage of forest species. Although α-diversity was similar between the two forest size classes, small forests often comprised matrix species, resulting in a higher β-diversity. Edge effects on the species richness of matrix species were noticeable up to 250 m into the forest. Hierarchical partitioning revealed that distance to disturbances (external edge, internal edges like roads) explained most assemblage variables, whereas forest size and woodland cover within a 1 km radius from the sites explained only a few assemblage variables. Densities of two forest-associated species, Discus rotundatus and Arion fuscus, decreased with forest size. Yet, forest size was positively correlated with richness of typical forest species and densities of Limax cinereoniger. The latter species seems to need forests of >1,000 ha, i.e., well above the size of most fragments. In conclusion, the prediction is valid only for forest species. The response to fragmentation is species specific and seems to depend on habitat specialization and macroclimatic conditions. Jean-Pierre Maelfait: Deceased.  相似文献   

Effect of moisture content during dry-heating on selected physicochemical and functional properties of dried egg white     

Van der Plancken I  Van Loey A  Hendrickx M 《Journal of agricultural and food chemistry》2007,55(1):127-135

This article addresses the effect of moisture content (0.8-9.9%) during dry-heating (80 degrees C) on selected physicochemical (solubility, turbidity, residual denaturation enthalpy, aggregation, surface hydrophobicity, and sulfhydryl content) and functional (foaming ability, foam density, and stability) properties of freeze-dried egg white (FDEW). Moisture content during dry-heating proved to be a parameter determining the functionality of the resulting egg white powder. The degree of conformational changes induced in the egg white proteins by dry-heating was strongly dependent on the amount of water present. Preferentially, dry-heating at 80 degrees C should be performed on egg white powder with a moisture content below 6.8%, as the loss of protein solubility above this value is extensive. In addition to insoluble aggregates, soluble, strongly stabilized aggregates were also formed, especially at higher moisture contents. The decrease in denaturation enthalpy, increase in surface hydrophobicity, and exposure of SH groups previously hidden in the protein core and their subsequent oxidation were more pronounced at prolonged dry-heating times and at higher moisture contents. These conformational changes resulted in improved foaming ability and foams with lower density. No effect of dry-heating on the foam stability was observed.  相似文献   

Comparison of mass spectrometry-based electronic nose and solid phase microextraction gas chromatography-mass spectrometry technique to assess infant formula oxidation     

Fenaille F  Visani P  Fumeaux R  Milo C  Guy PA 《Journal of agricultural and food chemistry》2003,51(9):2790-2796

Two headspace techniques based on mass spectrometry detection (MS), electronic nose, and solid phase microextraction coupled to gas chromatography-mass spectrometry (SPME-GC/MS) were evaluated for their ability to differentiate various infant formula powders based on changes of their volatiles upon storage. The electronic nose gave unresolved MS fingerprints of the samples gas phases that were further submitted to principal component analysis (PCA). Such direct MS recording combined to multivariate treatment enabled a rapid differentiation of the infant formulas over a 4 week storage test. Although MS-based electronic nose advantages are its easy-to-use aspect and its meaningful data interpretation obtained with a high throughput (100 samples per 24 h), its greatest disadvantage is that the present compounds could not be identified and quantified. For these reasons, a SPME-GC/MS measurement was also investigated. This technique allowed the identification of saturated aldehydes as the main volatiles present in the headspace of infant milk powders. An isotope dilution assay was further developed to quantitate hexanal as a potential indicator of infant milk powder oxidation. Thus, hexanal content was found to vary from roughly 500 and 3500 microg/kg for relatively non-oxidized and oxidized infant formulas, respectively.  相似文献